The Fe-containing intermetallic compounds with high melting point in hypereutectic Al-Si alloys can improve the heat resistance and wear resistance at elevated temperatures. However, the long needle-like Fe-containing...The Fe-containing intermetallic compounds with high melting point in hypereutectic Al-Si alloys can improve the heat resistance and wear resistance at elevated temperatures. However, the long needle-like Fe-containing compounds in the alloys produced by conventional casting process are detrimental to the strength of matrix. The effect of ultrasonic vibration (USV) on the morphology change of Fe-containing intermetallic compounds in the hypereutectic Al-17Si-xFe (x=2, 3, 4, 5) alloys was systematically studied. The results show that, the Fe-containing intermetallic compounds are mainly composed of long needle-like β-Al5FeSi phase with a small amount of plate-like δ-Al4FeSi2 phase in Al-17Si-2Fe alloy produced by conventional casting process. With the increase of Fe content from 2% to 5% in the alloys, the amount of plate-like or coarse needle-like δ-Al4FeSi2 phase increases while the amount of long needle-like β-Al5FeSi phases decreases. In Al-17Si-5Fe alloy, the Fe-containing intermetallic compounds exist mainly as coarse needle-like δ-Al4FeSi2 phase. After USV treatment, the Fe-containing compounds in the Al-17Si-xFe alloys are refined and exist mainly as δ-Al4FeSi2 particles, with average grain size ranging from 26 μm to 37 μm, and only a small amount of β-Al5FeSi phases remain. The mechanism of USV on the morphology of Fe-containing intermetallic compounds was also discussed.展开更多
A swash plate for air conditioning compressor of cars was formed by rheo-squeeze casting with semi-solid Al-Si alloy slurry prepared by ultrasonic vibration process, and the microstructure of this alloy was investigat...A swash plate for air conditioning compressor of cars was formed by rheo-squeeze casting with semi-solid Al-Si alloy slurry prepared by ultrasonic vibration process, and the microstructure of this alloy was investigated. Besides the microstructures of primary Si particles and α(Al)+β-Si eutectic phases, non-equilibrium α(Al) particles or dendrites are discovered in the microstructure of the Al-20Si-2Cu-0.4Mg-1Ni alloy. Rapid cooling generated by squeeze casting process rather than the pressure is considered as the main reason for the formation of non-equilibrium α(Al) phase. The sound pressurizing effect of ultrasonic vibration also enables the non-equilibrium α(Al) phases to form above eutectic temperature and grow into non-dendritic spheroids in the process of semi-solid slurry preparation. Non-equilibrium α(Al) phases formed in the hypereutectic Al-Si alloy with ultrasonic vibration treatment, consist of round α(Al) grains formed above the eutectic temperature and a small amount of fine α(Al) dendrites formed under the eutectic temperature. The volume fraction of primary Si particles is decreased significantly by the effect of ultrasonic vibration through increasing the solid solubility of Si atoms in α(Al) matrix and decreasing the forming temperature range of primary Si particles. The average particle diameter and the volume fraction of primary Si particles in microstructure of the swash-plate by rheo-squeeze casting are 24.3 μm and 11.1%, respectively.展开更多
O432.1 94020775双光子共振激发产生的钾原子紫外辐射=UV radiationgenerated by two-photon resonantexcitation in potassium vapor[刊,中]/梁吉平,贾锁堂,王钢(山西大学物理系)//山西大学学报(自然科学版).-1993,16(4).-395~398报...O432.1 94020775双光子共振激发产生的钾原子紫外辐射=UV radiationgenerated by two-photon resonantexcitation in potassium vapor[刊,中]/梁吉平,贾锁堂,王钢(山西大学物理系)//山西大学学报(自然科学版).-1993,16(4).-395~398报道了钾原子在双光子共振激发下,通过共振电离复合、碰撞能量转换过程、混频过程产生的红外受激辐射和紫外辐射。图4参4(许锦贤)O482.31 94020776多孔硅光致发光研究的最新进展=Recent developmentin research on photoluminescence展开更多
Anal fistula surgery is a commonly performed procedure.The diverse anatomy of anal fistulae and their proximity to anal sphincters make accurate preoperative diagnosis essential to avoid recurrence and fecal incontine...Anal fistula surgery is a commonly performed procedure.The diverse anatomy of anal fistulae and their proximity to anal sphincters make accurate preoperative diagnosis essential to avoid recurrence and fecal incontinence.Despite the fact that proper preoperative diagnosis can be reached in the majority of patients by simple clinical examination,endoanal ultrasound or magnetic resonance imaging,on many occasions,unexpected findings can be encountered during surgery that can make the operation difficult and correct decision-making crucial.In this article we discuss the difficulties and unexpected findings that can be encountered during anal fistula surgery and how to overcome them.展开更多
Objective To quantitatively evaluate the metabolic changes of benign prostatic hyperplasia(BPH) and prostate cancer in the transitional zone using magnetic resonance spectroscopic imaging(MRSI),and to analyze the char...Objective To quantitatively evaluate the metabolic changes of benign prostatic hyperplasia(BPH) and prostate cancer in the transitional zone using magnetic resonance spectroscopic imaging(MRSI),and to analyze the characteristics and differences of the spectra in this zonal area.Methods Eighteen patients with prostate cancer in the transitional zone underwent magnetic resonance imaging(MRI)/MRSI examinations.The(Choline+Creatine)/Citrate(CC/Ci) ratio and the Choline/Creatine(Cho/Cr) ratio were evaluated in each voxel with cancer or BPH confirmed by pathological results.Discriminant analysis was used to determine the power of the two ratios in differentiation between cancer and BPH.Results The CC/Ci ratio and Cho/Cr ratio for cancer voxels were significantly higher than those in the voxels with BPH in the transitional zone(CC/Ci:2.36±1.31 vs.0.85±0.29,P<0.01;Cho/Cr:4.14±1.79 vs.1.26±0.45,P<0.01).As for the discriminant function with the CC/Ci ratio and the Cho/Cr ratio,the specificity,sensitivity,and accuracy were 98.6%,85.7%,92.9% respectively for the differentiation between cancer and BPH.Conclusions The prostate cancer is characterized by higher CC/Ci ratio and Cho/Cr ratio compared to BPH in the transitional zone.Both CC/Ci ratio and Cho/Cr ratio have high specificity,sensitivity,and accuracy in their discriminative power between cancer and BPH in this zonal area.展开更多
The structure, spectroscopic properties and chemical stability of [VS4-(CuPPh3)3 (CuCl)Br2] in CDCl3 solution have been studied by multinuclear NMR tech-nique. Two peaks with relative intensity of 1: 4 are found in th...The structure, spectroscopic properties and chemical stability of [VS4-(CuPPh3)3 (CuCl)Br2] in CDCl3 solution have been studied by multinuclear NMR tech-nique. Two peaks with relative intensity of 1: 4 are found in the31P-{1H} spectra.Some 13C-{1H} and 1H NMR peaks have the same integral intensity ratio. These com-plemented the results of 31P-{1H} NMR. The experimental results demonstrates that the PPh3 ligand bound to Cu(6) is not equivalent with the four PPh3 ligands bound toCu(2) ~Cu (5 )- It affords an evidence that the title compound in the solution keepssimilar structure to solid state.展开更多
Objective:To study the diagnostic value of T2*-weighted first-pass perfusion imaging in breast tumors.Methods: We analyzed the magnetic resonance imaging(MRI)information along with the pathological and immunohistochem...Objective:To study the diagnostic value of T2*-weighted first-pass perfusion imaging in breast tumors.Methods: We analyzed the magnetic resonance imaging(MRI)information along with the pathological and immunohistochemistry re- sults.Magnetic resonance imaging was performed in 28 patients with breast tumor.The time to signal intensity curves were generated according to the T2*-weighted first-pass perfusion imaging.The curve’s maximal signal intensity drop rate and maximal signal intensity decrease time were analyzed and compared with the pathological diagnoses after surgery.Results: Malignant breast lesions showed higher maximal signal intensity drop rate(44.69%±17.07 vs.17.22%±7.49,P<0.001) than benign lesions,but there was no significant difference of maximal signal decrease time between those two lesions(23.94 s±4.92 vs.20.02 s±6.83,P>0.05).Conclusion:The T2*-weighted first-pass perfusion imaging has enough sensitivity and specificity in breast tumor diagnosis.展开更多
The basic-nitrogen aromatic compounds in feedstocks and liquid products from the micro-reactor and soluble components of coke obtained during fluid catalytic cracking (FCC) process were analyzed by the micro-electro...The basic-nitrogen aromatic compounds in feedstocks and liquid products from the micro-reactor and soluble components of coke obtained during fluid catalytic cracking (FCC) process were analyzed by the micro-electrospray ioniza- tion (ESI) 9.4T Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) with an average mass resolving power of 300 000 at a mass range of 100--1 200. The analytical results revealed that the coker gas oil (CGO) contained a higher abundance of basic-nitrogen aromatic compounds with the type of-SN to -9N compared with those in deasphalted oil (DAO) and mixed FCC feedstock. After catalytic cracking, the abundance of lowly condensed basic-nitrogen aromatic compounds was much less than those of highly condensed aromatics in the liquid products, with the carbon number mainly ranging from 6 to 25 and the average carbon number of the side-chains equating to 1--5. On the contrary, with respect to the soluble components of coke, the abundance of lowly condensed basic-nitrogen aromatic compounds was more than those of highly condensed aromatics, and the carbon number ranged from 12 to 30, which was much smaller than that of the mixed FCC feedstock but slightly larger than that of the cracked liquid products. These results have provided some fundamental information on FCC process.展开更多
Lignins were isolated and purified from alkali treated prehydrolysate of corn stover. The paper presents the structural features of lignins in a series purification processes. Fourier transform infrared spectroscopy, ...Lignins were isolated and purified from alkali treated prehydrolysate of corn stover. The paper presents the structural features of lignins in a series purification processes. Fourier transform infrared spectroscopy, ultraviolet-vis spectroscopy and proton nuclear magnetic resonance spectroscopy were used to analyze the chemical structure. Thermogravimetric analysis was applied to follow the thermal degradation, and wet chemical method was used to determine the sugar content. The results showed that the crude lignin from the prehydrolysate of corn stover was a heterogeneous material of syringyl, guaiacyl and p-hydroxyphenyl units, containing associated polysaccharides, lipids, and melted salts. Some of the crude lignin was chemically linked to hemicelluloses (mainly xylan). The lipids in crude lignin were probably composed of saturated and/or unsaturated long carbon chains, fatty acids, tdterpenols, waxes, and derivatives of aromatic. The sugar content of purified lignin was less than 2.11%, mainly composed of guaiacyl units. DTGmax of purified lignin was 359 ℃. The majority of the hydroxyl groups were phenolic hydroxyl groups. The main type of linkages in purified lignin was β-O-4. Other types of linkages included β-5, β-β and α-O-4.展开更多
The effects of pouring temperature,vibration frequency,and the number of curves in a serpentine channel,on themicrostructure and mechanical properties of Al-30%Si alloy processed by rheo-diecasting(RDC)were investigat...The effects of pouring temperature,vibration frequency,and the number of curves in a serpentine channel,on themicrostructure and mechanical properties of Al-30%Si alloy processed by rheo-diecasting(RDC)were investigated.The semisolidAl-30%Si alloy slurry was prepared by vibration serpentine channel pouring(VSCP)process in the RDC process.The results showthat the pouring temperature,the vibration frequency,and the number of the curves strongly affect the microstructure and mechanicalproperties of Al-30%Si alloy.Under experimental conditions of a pouring temperature of850°C,a twelve-curve copper channel anda vibration frequency of80Hz,the primary Si grains are refined into fine compact grains with average grain size of about24.6μm inthe RDC samples assisted with VSCP.Moreover,the ultimate tensile strength(UTS),elongation and hardness of the RDC sample are296MPa,0.87%and HB155,respectively.It is concluded that the VSCP process can effectively refine the primary Si grains.Therefinement of primary Si grains is the major cause for the improvement of the mechanical properties of the RDC sample.展开更多
Some unsaturated compounds with the required (Z,Z)-double bonds configuration are synthesized through controlled ozonolysis process of 1,5,9-cyclododecatriene by determining the necessary amount of ozone passing thr...Some unsaturated compounds with the required (Z,Z)-double bonds configuration are synthesized through controlled ozonolysis process of 1,5,9-cyclododecatriene by determining the necessary amount of ozone passing through to selectively guarantee the breakage of a double bond while leaving other two bonds as (Z,Z). The products were diagnosed by using NMR spectrum, infrared (IR) and mass spectrometer techniques. It is concluded that these products could widely be used in the synthesis of insect pheromones instead of insecticides and as useful intermediate compounds in many chemical reactions.展开更多
Starting from famous Schrodinger equation within the framework of semi-c/assicai theory of light-matter interaction, we firstly obtain the anaiytical non-resonant solutions of the driven bipartite system's entangleme...Starting from famous Schrodinger equation within the framework of semi-c/assicai theory of light-matter interaction, we firstly obtain the anaiytical non-resonant solutions of the driven bipartite system's entanglement dynamics in independent and coherent double pathways. Numerical simulations show that under non-resonant condition, entanglement sudden death and revival between these transition patterns behave quite differently, indicating the utmost importance of transition pathways' interference. Furthermore, the laser pulse's area and detuning exert significant but quite distinct influences on the entanglement dynamics. Our analyses are helpful in manipulating entanglement in current experimental technology.展开更多
In order to f urther improve the photosensitizing activity of hypocrellin B(HB), the complex o f 5,8 di Br HB with Al 3+ was designed and synthesized in high yield. Th e complex of aluminium ion with 5,8 di Br HB is a...In order to f urther improve the photosensitizing activity of hypocrellin B(HB), the complex o f 5,8 di Br HB with Al 3+ was designed and synthesized in high yield. Th e complex of aluminium ion with 5,8 di Br HB is a new water soluble perylene quinonoid derivative with enhanced absorption over HB in the phototherapeutic wi ndow (600-900 nm). Electron paramagnetic resonance (EPR) measurement and 9,10 diphenyl anthracene bleaching methods were used to investigate the photosensiti zing activity of [Al 2(5,8 di Br HB)Cl 4] n in the prese nce of oxygen. Singlet oxygen, superoxide anion radical, hydroxyl radical can be generated by [Al 2(5,8 di Br HB)Cl 4] n photosensit ization. The results showed that the production of hydroxyl radical ( · OH) by [Al 2(5,8 di Br HB)Cl 4] n photosensitization comes from the Fenton Haber Weiss reaction and the decom position of DMPO 1O 2 adduct. Formation of H 2O 2 as one of main intermedi ates in the photogeneration of hydroxyl radical was detected by using the cataly zed oxidation of the DPD reagent by the POD enzyme method. Moreover, the experim ents of EPR spin trap and catalase enzyme excluded the effect of organoperoxide on DPD oxidization. These results further support the proposed mechanism of · OH formation.展开更多
Time-resolved (TR)photoluminescence (PL) technique has shown great promise in ultrasensitive biodetection and high-resolution bioimaging.Hitherto,almost all the TRPL bioprobes are based on the parity-forbidden f→f tr...Time-resolved (TR)photoluminescence (PL) technique has shown great promise in ultrasensitive biodetection and high-resolution bioimaging.Hitherto,almost all the TRPL bioprobes are based on the parity-forbidden f→f transition of lanthanide ions.Herein,we report TRPL biosensing by taking advantage of the d→d transition of transition metal (TM)Mn^2+ ion.We demonstrate that the Forster resonance energy transfer (FRET)signal can be distinguished from that of radiative reabsorption process through measuring the PL lifetime of Mn^2+,thus establishing a reliable method for Mn^2+ in homogeneous TR-FRET biodetection.We also demonstrate the biotin receptor-targeted cancer cell imaging by utilizing biotinylated CaF2:Ce,Mn nanoprobes.Furthermore,we show in a proof-of-concept experiment the appli- cation of the long-lived PL of Mn^2+ for TRPL bioimaging through the burst shot with a cell phone.These findings provide a general approach for exploiting the long-lived PL of TM ions for TRPL biosensing,thereby opening up a new avenue for the exploration of novel and versatile applications of TM ions.展开更多
In this paper,we discuss the influences of channel blocks on the spiking regularity in a clustered neuronal network by applying stochastic Hodgkin-Huxley neuronal models as the building blocks.With the aid of simulati...In this paper,we discuss the influences of channel blocks on the spiking regularity in a clustered neuronal network by applying stochastic Hodgkin-Huxley neuronal models as the building blocks.With the aid of simulation results,we reveal that the spiking regularity of the clustered neuronal network could be resonantly enhanced via fine-tuning of the non-blocked potassium channel fraction xK.While the non-blocked sodium channel fraction xNa can enhance the spiking regularity of the clustered neuronal network in most cases.These results indicate that not only sodium channel blocks but also potassium channel blocks could have great influences on the regularity of spike timings in the clustered neuronal networks.Considering the importance of spike timings in neuronal information transforming processes,our results may give some implications for understanding the nonnegligible role of randomness in ion channels in neuronal systems.展开更多
Herein we investigated the electronic properties of layered transition-metal oxides NazTi2Sb2O by 23Na nuclear magnetic reso- nance (NMR) measurement. The resistivity, susceptibility and specific heat measurements s...Herein we investigated the electronic properties of layered transition-metal oxides NazTi2Sb2O by 23Na nuclear magnetic reso- nance (NMR) measurement. The resistivity, susceptibility and specific heat measurements show a phase transition at approxi- mately 114 K (TA). No splitting or broadening in the central line of 23Na NMR spectra is observed below and above the transi- tion temperature indicating no internal field being detected. The spin-lattice relaxation rate divided by T (I/T1T) shows a sharp drop at about 110 K which suggests a gap opening behavior. Below the phase transition temperature zone, I/T1T shows Fermi liquid behavior but with much smaller value indicating the loss of large part of electronic density of states (DOS) because of the gap. No signature of the enhancement of spin fluctuations or magnetic order is found with the decreasing temperature. These results suggest a commensurate charge-density-wave (CDW) phase transition occurring.展开更多
The effects of noise and a periodic signal on a synthetic gene network have been investigated. By tuning the distance of a parameter from the Hopf bifurcation point, both implicit internal signal stochastic resonance ...The effects of noise and a periodic signal on a synthetic gene network have been investigated. By tuning the distance of a parameter from the Hopf bifurcation point, both implicit internal signal stochastic resonance and explicit internal signal stochastic resonance can be induced by noise. Furthermore, a switch process can also be elicited. When a periodic signal is coupled to the gene network, two interesting phenomena occur with the modulation of the frequency of the signal: the effect of noise amplifying cellular signal can be inhibited or even destroyed, and "locked" coherence resonance occurs.展开更多
基金Project(2012CB619600)supported by the National Basic Research Program of ChinaProject(50775086)supported by the National Natural Science Foundation of China
文摘The Fe-containing intermetallic compounds with high melting point in hypereutectic Al-Si alloys can improve the heat resistance and wear resistance at elevated temperatures. However, the long needle-like Fe-containing compounds in the alloys produced by conventional casting process are detrimental to the strength of matrix. The effect of ultrasonic vibration (USV) on the morphology change of Fe-containing intermetallic compounds in the hypereutectic Al-17Si-xFe (x=2, 3, 4, 5) alloys was systematically studied. The results show that, the Fe-containing intermetallic compounds are mainly composed of long needle-like β-Al5FeSi phase with a small amount of plate-like δ-Al4FeSi2 phase in Al-17Si-2Fe alloy produced by conventional casting process. With the increase of Fe content from 2% to 5% in the alloys, the amount of plate-like or coarse needle-like δ-Al4FeSi2 phase increases while the amount of long needle-like β-Al5FeSi phases decreases. In Al-17Si-5Fe alloy, the Fe-containing intermetallic compounds exist mainly as coarse needle-like δ-Al4FeSi2 phase. After USV treatment, the Fe-containing compounds in the Al-17Si-xFe alloys are refined and exist mainly as δ-Al4FeSi2 particles, with average grain size ranging from 26 μm to 37 μm, and only a small amount of β-Al5FeSi phases remain. The mechanism of USV on the morphology of Fe-containing intermetallic compounds was also discussed.
基金Project (2009ZX04013-033) supported by the Major Scientific and Technological Special Project of ChinaProject (50775086) supported by the National Natural Science Foundation of China
文摘A swash plate for air conditioning compressor of cars was formed by rheo-squeeze casting with semi-solid Al-Si alloy slurry prepared by ultrasonic vibration process, and the microstructure of this alloy was investigated. Besides the microstructures of primary Si particles and α(Al)+β-Si eutectic phases, non-equilibrium α(Al) particles or dendrites are discovered in the microstructure of the Al-20Si-2Cu-0.4Mg-1Ni alloy. Rapid cooling generated by squeeze casting process rather than the pressure is considered as the main reason for the formation of non-equilibrium α(Al) phase. The sound pressurizing effect of ultrasonic vibration also enables the non-equilibrium α(Al) phases to form above eutectic temperature and grow into non-dendritic spheroids in the process of semi-solid slurry preparation. Non-equilibrium α(Al) phases formed in the hypereutectic Al-Si alloy with ultrasonic vibration treatment, consist of round α(Al) grains formed above the eutectic temperature and a small amount of fine α(Al) dendrites formed under the eutectic temperature. The volume fraction of primary Si particles is decreased significantly by the effect of ultrasonic vibration through increasing the solid solubility of Si atoms in α(Al) matrix and decreasing the forming temperature range of primary Si particles. The average particle diameter and the volume fraction of primary Si particles in microstructure of the swash-plate by rheo-squeeze casting are 24.3 μm and 11.1%, respectively.
文摘O432.1 94020775双光子共振激发产生的钾原子紫外辐射=UV radiationgenerated by two-photon resonantexcitation in potassium vapor[刊,中]/梁吉平,贾锁堂,王钢(山西大学物理系)//山西大学学报(自然科学版).-1993,16(4).-395~398报道了钾原子在双光子共振激发下,通过共振电离复合、碰撞能量转换过程、混频过程产生的红外受激辐射和紫外辐射。图4参4(许锦贤)O482.31 94020776多孔硅光致发光研究的最新进展=Recent developmentin research on photoluminescence
文摘Anal fistula surgery is a commonly performed procedure.The diverse anatomy of anal fistulae and their proximity to anal sphincters make accurate preoperative diagnosis essential to avoid recurrence and fecal incontinence.Despite the fact that proper preoperative diagnosis can be reached in the majority of patients by simple clinical examination,endoanal ultrasound or magnetic resonance imaging,on many occasions,unexpected findings can be encountered during surgery that can make the operation difficult and correct decision-making crucial.In this article we discuss the difficulties and unexpected findings that can be encountered during anal fistula surgery and how to overcome them.
文摘Objective To quantitatively evaluate the metabolic changes of benign prostatic hyperplasia(BPH) and prostate cancer in the transitional zone using magnetic resonance spectroscopic imaging(MRSI),and to analyze the characteristics and differences of the spectra in this zonal area.Methods Eighteen patients with prostate cancer in the transitional zone underwent magnetic resonance imaging(MRI)/MRSI examinations.The(Choline+Creatine)/Citrate(CC/Ci) ratio and the Choline/Creatine(Cho/Cr) ratio were evaluated in each voxel with cancer or BPH confirmed by pathological results.Discriminant analysis was used to determine the power of the two ratios in differentiation between cancer and BPH.Results The CC/Ci ratio and Cho/Cr ratio for cancer voxels were significantly higher than those in the voxels with BPH in the transitional zone(CC/Ci:2.36±1.31 vs.0.85±0.29,P<0.01;Cho/Cr:4.14±1.79 vs.1.26±0.45,P<0.01).As for the discriminant function with the CC/Ci ratio and the Cho/Cr ratio,the specificity,sensitivity,and accuracy were 98.6%,85.7%,92.9% respectively for the differentiation between cancer and BPH.Conclusions The prostate cancer is characterized by higher CC/Ci ratio and Cho/Cr ratio compared to BPH in the transitional zone.Both CC/Ci ratio and Cho/Cr ratio have high specificity,sensitivity,and accuracy in their discriminative power between cancer and BPH in this zonal area.
文摘The structure, spectroscopic properties and chemical stability of [VS4-(CuPPh3)3 (CuCl)Br2] in CDCl3 solution have been studied by multinuclear NMR tech-nique. Two peaks with relative intensity of 1: 4 are found in the31P-{1H} spectra.Some 13C-{1H} and 1H NMR peaks have the same integral intensity ratio. These com-plemented the results of 31P-{1H} NMR. The experimental results demonstrates that the PPh3 ligand bound to Cu(6) is not equivalent with the four PPh3 ligands bound toCu(2) ~Cu (5 )- It affords an evidence that the title compound in the solution keepssimilar structure to solid state.
基金a grant from the Medicine Scientific Development Foun-dation of Nanjing(No.zkx05021).
文摘Objective:To study the diagnostic value of T2*-weighted first-pass perfusion imaging in breast tumors.Methods: We analyzed the magnetic resonance imaging(MRI)information along with the pathological and immunohistochemistry re- sults.Magnetic resonance imaging was performed in 28 patients with breast tumor.The time to signal intensity curves were generated according to the T2*-weighted first-pass perfusion imaging.The curve’s maximal signal intensity drop rate and maximal signal intensity decrease time were analyzed and compared with the pathological diagnoses after surgery.Results: Malignant breast lesions showed higher maximal signal intensity drop rate(44.69%±17.07 vs.17.22%±7.49,P<0.001) than benign lesions,but there was no significant difference of maximal signal decrease time between those two lesions(23.94 s±4.92 vs.20.02 s±6.83,P>0.05).Conclusion:The T2*-weighted first-pass perfusion imaging has enough sensitivity and specificity in breast tumor diagnosis.
基金supported by the National Basic Research Program of China (2010CB226901)
文摘The basic-nitrogen aromatic compounds in feedstocks and liquid products from the micro-reactor and soluble components of coke obtained during fluid catalytic cracking (FCC) process were analyzed by the micro-electrospray ioniza- tion (ESI) 9.4T Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) with an average mass resolving power of 300 000 at a mass range of 100--1 200. The analytical results revealed that the coker gas oil (CGO) contained a higher abundance of basic-nitrogen aromatic compounds with the type of-SN to -9N compared with those in deasphalted oil (DAO) and mixed FCC feedstock. After catalytic cracking, the abundance of lowly condensed basic-nitrogen aromatic compounds was much less than those of highly condensed aromatics in the liquid products, with the carbon number mainly ranging from 6 to 25 and the average carbon number of the side-chains equating to 1--5. On the contrary, with respect to the soluble components of coke, the abundance of lowly condensed basic-nitrogen aromatic compounds was more than those of highly condensed aromatics, and the carbon number ranged from 12 to 30, which was much smaller than that of the mixed FCC feedstock but slightly larger than that of the cracked liquid products. These results have provided some fundamental information on FCC process.
基金Supported by the National Natural Science Foundation of China (20876078, 21176124), the National High Technology Research and Development Program of China (2011AA02A207), the National Basic Research Program of China (2009CB724700), the Key Program of the National Natural Science Foundation of China (20936002), and the Independent Innovation Project of Jiangsu Province (CX(11)2051).
文摘Lignins were isolated and purified from alkali treated prehydrolysate of corn stover. The paper presents the structural features of lignins in a series purification processes. Fourier transform infrared spectroscopy, ultraviolet-vis spectroscopy and proton nuclear magnetic resonance spectroscopy were used to analyze the chemical structure. Thermogravimetric analysis was applied to follow the thermal degradation, and wet chemical method was used to determine the sugar content. The results showed that the crude lignin from the prehydrolysate of corn stover was a heterogeneous material of syringyl, guaiacyl and p-hydroxyphenyl units, containing associated polysaccharides, lipids, and melted salts. Some of the crude lignin was chemically linked to hemicelluloses (mainly xylan). The lipids in crude lignin were probably composed of saturated and/or unsaturated long carbon chains, fatty acids, tdterpenols, waxes, and derivatives of aromatic. The sugar content of purified lignin was less than 2.11%, mainly composed of guaiacyl units. DTGmax of purified lignin was 359 ℃. The majority of the hydroxyl groups were phenolic hydroxyl groups. The main type of linkages in purified lignin was β-O-4. Other types of linkages included β-5, β-β and α-O-4.
基金Project(5077400) supported by the National Natural Science Foundation of China
文摘The effects of pouring temperature,vibration frequency,and the number of curves in a serpentine channel,on themicrostructure and mechanical properties of Al-30%Si alloy processed by rheo-diecasting(RDC)were investigated.The semisolidAl-30%Si alloy slurry was prepared by vibration serpentine channel pouring(VSCP)process in the RDC process.The results showthat the pouring temperature,the vibration frequency,and the number of the curves strongly affect the microstructure and mechanicalproperties of Al-30%Si alloy.Under experimental conditions of a pouring temperature of850°C,a twelve-curve copper channel anda vibration frequency of80Hz,the primary Si grains are refined into fine compact grains with average grain size of about24.6μm inthe RDC samples assisted with VSCP.Moreover,the ultimate tensile strength(UTS),elongation and hardness of the RDC sample are296MPa,0.87%and HB155,respectively.It is concluded that the VSCP process can effectively refine the primary Si grains.Therefinement of primary Si grains is the major cause for the improvement of the mechanical properties of the RDC sample.
文摘Some unsaturated compounds with the required (Z,Z)-double bonds configuration are synthesized through controlled ozonolysis process of 1,5,9-cyclododecatriene by determining the necessary amount of ozone passing through to selectively guarantee the breakage of a double bond while leaving other two bonds as (Z,Z). The products were diagnosed by using NMR spectrum, infrared (IR) and mass spectrometer techniques. It is concluded that these products could widely be used in the synthesis of insect pheromones instead of insecticides and as useful intermediate compounds in many chemical reactions.
基金Supported by the National Basic Research Program(973 Program)of China under Grant No.2012CB921900the National Natural Science Foundation of China under Grant No.10574166the Guangdong Natural Science Foundation under Grant No.8151027501000062
文摘Starting from famous Schrodinger equation within the framework of semi-c/assicai theory of light-matter interaction, we firstly obtain the anaiytical non-resonant solutions of the driven bipartite system's entanglement dynamics in independent and coherent double pathways. Numerical simulations show that under non-resonant condition, entanglement sudden death and revival between these transition patterns behave quite differently, indicating the utmost importance of transition pathways' interference. Furthermore, the laser pulse's area and detuning exert significant but quite distinct influences on the entanglement dynamics. Our analyses are helpful in manipulating entanglement in current experimental technology.
文摘In order to f urther improve the photosensitizing activity of hypocrellin B(HB), the complex o f 5,8 di Br HB with Al 3+ was designed and synthesized in high yield. Th e complex of aluminium ion with 5,8 di Br HB is a new water soluble perylene quinonoid derivative with enhanced absorption over HB in the phototherapeutic wi ndow (600-900 nm). Electron paramagnetic resonance (EPR) measurement and 9,10 diphenyl anthracene bleaching methods were used to investigate the photosensiti zing activity of [Al 2(5,8 di Br HB)Cl 4] n in the prese nce of oxygen. Singlet oxygen, superoxide anion radical, hydroxyl radical can be generated by [Al 2(5,8 di Br HB)Cl 4] n photosensit ization. The results showed that the production of hydroxyl radical ( · OH) by [Al 2(5,8 di Br HB)Cl 4] n photosensitization comes from the Fenton Haber Weiss reaction and the decom position of DMPO 1O 2 adduct. Formation of H 2O 2 as one of main intermedi ates in the photogeneration of hydroxyl radical was detected by using the cataly zed oxidation of the DPD reagent by the POD enzyme method. Moreover, the experim ents of EPR spin trap and catalase enzyme excluded the effect of organoperoxide on DPD oxidization. These results further support the proposed mechanism of · OH formation.
基金supported by National Program on Key Basic Research Project (973 Program, 2014CB845605) the Strategic Priority Research Program of the CAS (XDB20000000)+3 种基金 the National Natural Science Foundation of China (21325104, 11774345, 21771185, 21501180 and 21650110462)the CAS/SAFEA International Partnership Program for Creative Re-search Teams, the Youth Innovation Promotion Association (2016277)the Chunmiao Project of Haixi Institutes of the CAS (CMZX-2016-002)Natural Science Foundation of Fujian Province (2017I0018 and 2017J05095)
文摘Time-resolved (TR)photoluminescence (PL) technique has shown great promise in ultrasensitive biodetection and high-resolution bioimaging.Hitherto,almost all the TRPL bioprobes are based on the parity-forbidden f→f transition of lanthanide ions.Herein,we report TRPL biosensing by taking advantage of the d→d transition of transition metal (TM)Mn^2+ ion.We demonstrate that the Forster resonance energy transfer (FRET)signal can be distinguished from that of radiative reabsorption process through measuring the PL lifetime of Mn^2+,thus establishing a reliable method for Mn^2+ in homogeneous TR-FRET biodetection.We also demonstrate the biotin receptor-targeted cancer cell imaging by utilizing biotinylated CaF2:Ce,Mn nanoprobes.Furthermore,we show in a proof-of-concept experiment the appli- cation of the long-lived PL of Mn^2+ for TRPL bioimaging through the burst shot with a cell phone.These findings provide a general approach for exploiting the long-lived PL of TM ions for TRPL biosensing,thereby opening up a new avenue for the exploration of novel and versatile applications of TM ions.
基金supported by the National Natural Science Foundation of China(Grant Nos.1110209411272065)the Fundamental Research Funds for the Central University of China(Grant No.2013RC0904)
文摘In this paper,we discuss the influences of channel blocks on the spiking regularity in a clustered neuronal network by applying stochastic Hodgkin-Huxley neuronal models as the building blocks.With the aid of simulation results,we reveal that the spiking regularity of the clustered neuronal network could be resonantly enhanced via fine-tuning of the non-blocked potassium channel fraction xK.While the non-blocked sodium channel fraction xNa can enhance the spiking regularity of the clustered neuronal network in most cases.These results indicate that not only sodium channel blocks but also potassium channel blocks could have great influences on the regularity of spike timings in the clustered neuronal networks.Considering the importance of spike timings in neuronal information transforming processes,our results may give some implications for understanding the nonnegligible role of randomness in ion channels in neuronal systems.
基金supported by the National Natural Science Foundation of China(Grant No.11025422)the National Basic Research Program of China(Grant No.2011CB921701)
文摘Herein we investigated the electronic properties of layered transition-metal oxides NazTi2Sb2O by 23Na nuclear magnetic reso- nance (NMR) measurement. The resistivity, susceptibility and specific heat measurements show a phase transition at approxi- mately 114 K (TA). No splitting or broadening in the central line of 23Na NMR spectra is observed below and above the transi- tion temperature indicating no internal field being detected. The spin-lattice relaxation rate divided by T (I/T1T) shows a sharp drop at about 110 K which suggests a gap opening behavior. Below the phase transition temperature zone, I/T1T shows Fermi liquid behavior but with much smaller value indicating the loss of large part of electronic density of states (DOS) because of the gap. No signature of the enhancement of spin fluctuations or magnetic order is found with the decreasing temperature. These results suggest a commensurate charge-density-wave (CDW) phase transition occurring.
基金supported by the National Natural Science Foundation of China (20905009 and 21003010)the Logistics Management & Engineering Platform of Beijing Area Logistics System & Technology Major Laboratory, and Excellent Young Scholars Research Fund of Beijing Institute of Technology (2009 Y1017)
文摘The effects of noise and a periodic signal on a synthetic gene network have been investigated. By tuning the distance of a parameter from the Hopf bifurcation point, both implicit internal signal stochastic resonance and explicit internal signal stochastic resonance can be induced by noise. Furthermore, a switch process can also be elicited. When a periodic signal is coupled to the gene network, two interesting phenomena occur with the modulation of the frequency of the signal: the effect of noise amplifying cellular signal can be inhibited or even destroyed, and "locked" coherence resonance occurs.