In conventional source-filter models, voiced and unvoiced components were considered independently. However, in practice it was difficult to separate the source into two parts. An actual source consists of a mixture o...In conventional source-filter models, voiced and unvoiced components were considered independently. However, in practice it was difficult to separate the source into two parts. An actual source consists of a mixture of two sources and the ratio varies according to the content or the intention of speaker. It had been investigated to separate the voiced and unvoiced components for different source models. Source signals were modeled based on the residual signal measured from inverse filtering. Three different source models were assumed. The parameters of each model were optimized for the original speech signal using a genetic algorithm. The resulting parameters were compared in terms of the mel-cepstral distance to the original signal, the spectrogram and the spectral envelope from the synthesized signal. The optimization method achieves an improvement of 15% for the Klatt model, but there is little improvement in the modified residual case.展开更多
The filter-based reactive packet filtering is a key technology in attack traffic filtering for defending against the Denial-of- Service （DOS） attacks. Two kinds of relevant schemes have been proposed as victim- end ...The filter-based reactive packet filtering is a key technology in attack traffic filtering for defending against the Denial-of- Service （DOS） attacks. Two kinds of relevant schemes have been proposed as victim- end filtering and source-end filtering. The first scheme prevents attack traffic from reaching the victim, but causes the huge loss of legitimate flows due to the scarce filters （termed as collateral damages）; the other extreme scheme can obtain the sufficient filters, but severely degrades the network transmission performance due to the abused filtering routers. In this paper, we propose a router based packet filtering scheme, which provides relatively more filters while reducing the quantity of filtering touters. We implement this scheme on the emulated DoS scenarios based on the synthetic and real-world Internet topologies. Our evaluation results show that compared to the previous work, our scheme just uses 20% of its filtering routers, but only increasing less than 15 percent of its collateral damage.展开更多
A transmission bottleneck occurs during each human immunodeficiency virus(HIV) transmission event, which allows only a few viruses to establish new infection. However, the genetic characteristics of the transmitted vi...A transmission bottleneck occurs during each human immunodeficiency virus(HIV) transmission event, which allows only a few viruses to establish new infection. However, the genetic characteristics of the transmitted viruses that are preferentially selected have not been fully elucidated. Here, we analyzed amino acids changes in the envelope protein during simian immunodeficiency virus(SIV)/HIV deep transmission history and current HIV evolution within the last 15–20 years. Our results confirmed that the V1V2 region of gp120 protein, particularly V1, was preferentially selected. A shorter V1 region was preferred during transmission history, while during epidemic, HIV may evolve to an expanded V1 region gradually and thus escape immune recognition. We then constructed different HIV-1 V1 mutants using different HIV-1 subtypes to elucidate the role of the V1 region in envelope function. We found that the V1 region, although highly variable, was indispensable for virus entry and infection, probably because V1 deletion mutants exhibited impaired processing of gp160 into mature gp120 and gp41. Additionally, the V1 region affected Env incorporation. These results indicated that the V1 region played a critical role in HIV transmission and infection.展开更多
基金supported by the Second Stage of Brain Korea 21 Projects
文摘In conventional source-filter models, voiced and unvoiced components were considered independently. However, in practice it was difficult to separate the source into two parts. An actual source consists of a mixture of two sources and the ratio varies according to the content or the intention of speaker. It had been investigated to separate the voiced and unvoiced components for different source models. Source signals were modeled based on the residual signal measured from inverse filtering. Three different source models were assumed. The parameters of each model were optimized for the original speech signal using a genetic algorithm. The resulting parameters were compared in terms of the mel-cepstral distance to the original signal, the spectrogram and the spectral envelope from the synthesized signal. The optimization method achieves an improvement of 15% for the Klatt model, but there is little improvement in the modified residual case.
基金supported in part by the funding agencies of china:the Doctoral Fund of Northeastern University of Qinhuangdao(Grant No.XNB201410)the Fundamental Research Funds for the Central Universities(Grant No.N130323005)
文摘The filter-based reactive packet filtering is a key technology in attack traffic filtering for defending against the Denial-of- Service （DOS） attacks. Two kinds of relevant schemes have been proposed as victim- end filtering and source-end filtering. The first scheme prevents attack traffic from reaching the victim, but causes the huge loss of legitimate flows due to the scarce filters （termed as collateral damages）; the other extreme scheme can obtain the sufficient filters, but severely degrades the network transmission performance due to the abused filtering routers. In this paper, we propose a router based packet filtering scheme, which provides relatively more filters while reducing the quantity of filtering touters. We implement this scheme on the emulated DoS scenarios based on the synthetic and real-world Internet topologies. Our evaluation results show that compared to the previous work, our scheme just uses 20% of its filtering routers, but only increasing less than 15 percent of its collateral damage.
基金supported by the International Science & Technology Cooperation Program of China (2011DFA31030)Deutsche Forschungsgemeinschaft (Transregio TRR60),National Natural Science Foundation of China (No.81461130019)
文摘A transmission bottleneck occurs during each human immunodeficiency virus(HIV) transmission event, which allows only a few viruses to establish new infection. However, the genetic characteristics of the transmitted viruses that are preferentially selected have not been fully elucidated. Here, we analyzed amino acids changes in the envelope protein during simian immunodeficiency virus(SIV)/HIV deep transmission history and current HIV evolution within the last 15–20 years. Our results confirmed that the V1V2 region of gp120 protein, particularly V1, was preferentially selected. A shorter V1 region was preferred during transmission history, while during epidemic, HIV may evolve to an expanded V1 region gradually and thus escape immune recognition. We then constructed different HIV-1 V1 mutants using different HIV-1 subtypes to elucidate the role of the V1 region in envelope function. We found that the V1 region, although highly variable, was indispensable for virus entry and infection, probably because V1 deletion mutants exhibited impaired processing of gp160 into mature gp120 and gp41. Additionally, the V1 region affected Env incorporation. These results indicated that the V1 region played a critical role in HIV transmission and infection.
