Although metastatic breast cancer is considered as an incurable disease, various biological drivers influence the outcomes. The use of trastuzumab in patients overexpressing HER(human epidermal growth factor recepto...Although metastatic breast cancer is considered as an incurable disease, various biological drivers influence the outcomes. The use of trastuzumab in patients overexpressing HER(human epidermal growth factor receptor 2)-2 increases long-term survival even in those patients who developed brain metastasis. Nevertheless, special attention must be paid to the risk of cardiotoxicity. We report the case of a young woman with HER-2-positive breast cancer with bone and lung disease who developed brain metastasis during treatment with trastuzumab. The treatment has been continued and she is alive and in complete remission after 16 years.展开更多
We consider a class of stochastic Boussinesq equations driven by L6vy processes and establish the uniqueness of its invariant measure. The proof is based on the progressive stopping time technique.
文摘Although metastatic breast cancer is considered as an incurable disease, various biological drivers influence the outcomes. The use of trastuzumab in patients overexpressing HER(human epidermal growth factor receptor 2)-2 increases long-term survival even in those patients who developed brain metastasis. Nevertheless, special attention must be paid to the risk of cardiotoxicity. We report the case of a young woman with HER-2-positive breast cancer with bone and lung disease who developed brain metastasis during treatment with trastuzumab. The treatment has been continued and she is alive and in complete remission after 16 years.
基金supported by National Natural Science Foundation of China (Grant Nos.10971225 and 11101427)Natural Science Foundation of Hunan Province (Grant No. 11JJ3004)the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State the Ministry of Education of China
文摘We consider a class of stochastic Boussinesq equations driven by L6vy processes and establish the uniqueness of its invariant measure. The proof is based on the progressive stopping time technique.