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糖尿病慢传输运动结肠Cajal间质细胞和干细胞因子的变化 被引量:20
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作者 罗云 林琳 +3 位作者 张红杰 李学良 吴高珏 王美峰 《世界华人消化杂志》 CAS 北大核心 2007年第5期458-463,共6页
目的:了解Cajal间质细胞(ICC)、干细胞因子(SCF)在糖尿病大鼠结肠慢传输运动模型中的变化,探讨其作用及可能的调控机制.方法:54只♂SD大鼠分为糖尿病和正常对照组,经腹腔注射链脲佐菌素建立糖尿病大鼠模型,于造模后6,8,10wk各组分别处死... 目的:了解Cajal间质细胞(ICC)、干细胞因子(SCF)在糖尿病大鼠结肠慢传输运动模型中的变化,探讨其作用及可能的调控机制.方法:54只♂SD大鼠分为糖尿病和正常对照组,经腹腔注射链脲佐菌素建立糖尿病大鼠模型,于造模后6,8,10wk各组分别处死9只大鼠,以免疫组化、透射电镜研究近端结肠组织中ICC的变化,以Westernblot方法检测近端结肠组织中膜结合型干细胞因子的表达,以ELISA测定血清中可溶型SCF的浓度,分析他们之间的相关性.结果:糖尿病大鼠血糖随时间增加而升高,而胃肠推进率却降低(P>0.05).免疫组化结果显示,6,8,10wk时的糖尿病大鼠肌间ICC表达较对照组明显减少(P<0.05),且糖尿病大鼠近端结肠ICC数量随时间推移有逐渐降少的趋势.透射电镜显示糖尿病大鼠结肠ICC线粒体肿胀、空泡样变,细胞器数量明显减少.与对照组相比,糖尿病大鼠血清中可溶型SCF显著降低(6wk:0.93±0.53μg/Lvs1.87±0.92μg/L,P<0.05;8wk:0.78±0.21μg/Lvs1.76±0.94μg/L,P<0.05;10wk:0.73±0.20μg/Lvs1.82±0.96μg/L,P<0.05),而结肠组织中的膜结合型SCF无明显差异(P>0.05),且可溶型干细胞因子与ICC具有相同的变化趋势.结论:糖尿病胃肠动力障碍大鼠存在血清中可溶性干细胞因子浓度下降以及结肠组织中ICC数量减少和结构破坏,这些变化及其可能存在的序贯性调控作用可能是糖尿病出现结肠慢传输变化的基础. 展开更多
关键词 干细胞因子 糖尿病 结肠慢传输运动 CAJAL间质细胞
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慢传输运动小鼠结肠组织中Cajal间质细胞的改变 被引量:16
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作者 林琳 姜柳琴 +3 位作者 张红杰 胡晔东 林征 黄峻 《胃肠病学》 2006年第8期462-467,共6页
背景:慢传输型便秘的发病机制尚不清楚。近年Cajal间质细胞(interstitialcellsofCajal,ICC)对胃肠平滑肌的起搏作用和介导神经递质的作用已被人们所认识,且在一些胃肠动力障碍性疾病中存在ICC数量和结构的异常改变。目的:探讨ICC在慢传... 背景:慢传输型便秘的发病机制尚不清楚。近年Cajal间质细胞(interstitialcellsofCajal,ICC)对胃肠平滑肌的起搏作用和介导神经递质的作用已被人们所认识,且在一些胃肠动力障碍性疾病中存在ICC数量和结构的异常改变。目的:探讨ICC在慢传输运动小鼠结肠组织中的改变。方法:经吗啡诱导建立结肠慢传输运动小鼠模型,采用免疫组化法观察各组小鼠结肠组织ICC的表达和分布;采用Westernblot蛋白印迹试验和逆转录聚合酶链反应(RT-PCR)分析各组小鼠结肠组织c-Kit蛋白和c-kitmRNA的表达。结果:①45天后两实验组小鼠近端结肠组织免疫组化c-kit阳性细胞较对照组显著减少(P<0.01),实验组Ⅱ较实验组Ⅰc-kit阳性细胞减少更明显(P<0.01);60天后停吗啡组的c-kit阳性细胞较纳洛酮阻断组和对照组显著减少(P<0.01)。小鼠远端结肠组织c-kit阳性细胞在所有组别之间无显著差异。②45天后两实验组小鼠近端结肠组织c-Kit蛋白和c-kitmRNA的表达较对照组均显著减少(P均<0.01);60天后停吗啡组近端结肠组织c-Kit蛋白和c-kitmRNA的表达仍较纳洛酮阻断组和对照组显著减少(P<0.05和P<0.01)。结论:吗啡诱导的慢传输运动小鼠近端结肠组织中ICC数量下降,c-Kit蛋白和c-kitmRNA的表达明显减少,提示近端结肠ICC减少可能是结肠慢传输运动的原因之一;停用吗啡未能逆转ICC的变化,结肠慢传输运动也无改善。纳洛酮阻断后,ICC的变化基本恢复,结肠动力改善,纳洛酮可能阻止和恢复吗啡诱导的ICC数量的变化。 展开更多
关键词 小鼠 结肠 传输运动 CAJAL间质细胞 原癌基因蛋白质c—kit RNA 信使
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结肠慢传输运动小鼠模型建立的初步探讨 被引量:8
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作者 林琳 姜柳琴 +4 位作者 张红杰 胡晔东 林征 王美峰 黄峻 《诊断学理论与实践》 2006年第1期31-34,共4页
目的:建立结肠慢传输运动实验动物模型,为探讨慢传输型便秘发病学提供基础。方法:小鼠皮下注射吗啡建立结肠慢传输运动实验模型,比较各组小鼠日平均粪便重量、粪便性状及活性炭悬液推进试验。结果:①日平均粪便重量:a吗啡组比对照组减少... 目的:建立结肠慢传输运动实验动物模型,为探讨慢传输型便秘发病学提供基础。方法:小鼠皮下注射吗啡建立结肠慢传输运动实验模型,比较各组小鼠日平均粪便重量、粪便性状及活性炭悬液推进试验。结果:①日平均粪便重量:a吗啡组比对照组减少(P<0.05);b停吗啡组仍较对照组减少(P<0.01),纳洛酮阻断后各组与对照组无差异,但大剂量吗啡组恢复较慢;②粪便性状:吗啡组较对照组明显干硬;停吗啡组无改善,纳洛酮阻断后粪便性状改善;③肠道推进率:a吗啡组比对照组减少(P<0.01);b停用吗啡组仍较对照组减低(P<0.01),纳洛酮阻断后各组较对照组无差异,但大剂量吗啡组恢复不理想。结论:吗啡诱导的小鼠结肠慢传输运动模型日平均粪便重量减少、粪便性状变干硬、肠道推进率明显减慢。停药后未使肠道运动逆转;而纳洛酮阻断后可以使肠道运动功能基本恢复。该模型基本符合慢传输型便秘临床特征。 展开更多
关键词 结肠慢传输运动 吗啡 纳洛酮 肠道推进率 小鼠
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扩频通信技术及其在远动信号传输中的应用 被引量:1
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作者 富璇 王彤 《沈阳工程学院学报(自然科学版)》 1999年第1期53-55,共3页
本文简要叙述了扩展频谱通信系统的工作原理,分析了扩频通信的主要特点及技术指标,指出了扩频通信在未来的通信领域中的广阔发展前景,特别是在电力系统远动信号传输中的应用,使得调度通信网的远程监控系统更加灵活、方便、可靠。
关键词 扩展频谱通信 直接序列扩频 运动信号传输
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基于深度信息的人体运动识别方法 被引量:2
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作者 陈力 王俊凯 张玉玺 《太赫兹科学与电子信息学报》 2016年第3期443-448,共6页
近年来,可见光视频序列的人体运动识别研究已经取得了一定的进展。由于这些数据源容易受到目标颜色、光照强度和背景杂波的影响,因此将深度信息应用于人体运动识别。本文首先采用了基于时空兴趣点的人体运动的局部表征方法,分别实现了Ha... 近年来,可见光视频序列的人体运动识别研究已经取得了一定的进展。由于这些数据源容易受到目标颜色、光照强度和背景杂波的影响,因此将深度信息应用于人体运动识别。本文首先采用了基于时空兴趣点的人体运动的局部表征方法,分别实现了Harris时空兴趣点与基于Gabor滤波器的时空兴趣点(STIPs)检测方法在深度信息上的应用。然后对相应结果进行立方体描述并提取了深度立方体相似特征(DCSF)。最后利用基于时空码本的支持向量机(SVM)动作分类器完成对动作的分类。实验表明,基于Gabor滤波器的检测方法在深度数据集上取得了更好的识别效果。 展开更多
关键词 分层传输运动分析 运动识别 时空兴趣点 运动表征 SVM分类
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基于序列图像的排种器性能检测方法 被引量:23
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作者 胡少兴 查红彬 马成林 《农业机械学报》 EI CAS CSCD 北大核心 2004年第1期52-55,64,共5页
通过分析序列图像的特点和种子目标的运动规律 ,提出了基于序列图像的排种器性能检测方法。包括种子的初速度确定、空间位置坐标变换、离开排种口的时间、图像采集间隔的求取、序列图像空间点的递推拼合、种子水平间距的确定 ,进而获得... 通过分析序列图像的特点和种子目标的运动规律 ,提出了基于序列图像的排种器性能检测方法。包括种子的初速度确定、空间位置坐标变换、离开排种口的时间、图像采集间隔的求取、序列图像空间点的递推拼合、种子水平间距的确定 ,进而获得表征排种均匀度的各种特征量。实验证明 ,基于计算机视觉的排种器性能检测系统的结果可靠 。 展开更多
关键词 序列图像 排种器 性能检测 匀速直线运动传输
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环法自行车赛电视转播方案介绍 被引量:5
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作者 伯纳德.皮查特 《现代电视技术》 2004年第4期69-70,75,共3页
环法自行车赛从1903年开始到今天已有百年历史,中央电视台自2001年开始也进行了电视转播报道.从电视转播中我们不仅目睹了运动员的风采,而且通过镜头欣赏到了法国的秀美景色.这些都是通过什么手段实现的呢?
关键词 电视转播 环法自行车赛 运动拍摄 运动传输 电视节目制作
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内源性一氧化碳和Cajal间质细胞在糖尿病结肠功能紊乱中的作用
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作者 吴高珏 林琳 《国际内科学杂志》 CAS 2007年第10期593-596,共4页
糖尿病胃肠功能紊乱是糖尿病常见的并发症,严重影响患者的生活质量和血糖的控制。胃肠道一氧化碳和Cajal间质细胞在维持胃肠功能中发挥重要作用,两者在糖尿病结肠组织中均有异常改变,影响糖尿病结肠运动。本文就其在糖尿病结肠功能紊乱... 糖尿病胃肠功能紊乱是糖尿病常见的并发症,严重影响患者的生活质量和血糖的控制。胃肠道一氧化碳和Cajal间质细胞在维持胃肠功能中发挥重要作用,两者在糖尿病结肠组织中均有异常改变,影响糖尿病结肠运动。本文就其在糖尿病结肠功能紊乱中的作用作一综述。 展开更多
关键词 内源性一氧化碳 CAJAL间质细胞 糖尿病 结肠功能紊乱 传输运动
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Hydrodynamic Instabilities Driven by Acid-base Neutralization Reaction in Immiscible System 被引量:1
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作者 Asad Ahemd 杨雅辉 +1 位作者 柴川 吴江涛 《Chinese Journal of Chemical Physics》 SCIE CAS CSCD 2010年第5期513-520,621,共9页
The hydrodynamic instabilities driven by an acid-base neutralization reaction, in contact along a plane interface, placed in a Hele-Shaw cell under the gravitational field are reported. The system consists of the heav... The hydrodynamic instabilities driven by an acid-base neutralization reaction, in contact along a plane interface, placed in a Hele-Shaw cell under the gravitational field are reported. The system consists of the heavier aqueous tetramethyle-ammonium hydroxide below the lighter layer of organic phase with propionic acid as reacting specie. The effect of chemical composition on hydrodynamic instabilities during interfacial mass transfer accompanied by a neutralization reaction is investigated. Depending on the initial concentration of the reacting species, Marangoni convection in the form of roll ceils or trains of waves is observed. Mach- Zehnder interferometer is used to measure the change in base concentration at the time of instability formation. The results show that the instabilities resulted from the convection flow are more efficient to the mechanism of mass transfer and can drastically alter pattern formation in the system. 展开更多
关键词 Fluid dynamics Convective transport DIFFUSION INTERFACE Mass transfer Chemical reactor
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Mixed convective heat and mass transfer analysis for peristaltic transport in an asymmetric channel with Soret and Dufour effects 被引量:5
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作者 F.M.Abbasi A.Alsaedi T.Hayat 《Journal of Central South University》 SCIE EI CAS 2014年第12期4585-4591,共7页
The present investigation addresses the simultaneous effects of heat and mass transfer in the mixed convection peristaltic flow of viscous fluid in an asymmetric channel. The channel walls exhibit the convective bound... The present investigation addresses the simultaneous effects of heat and mass transfer in the mixed convection peristaltic flow of viscous fluid in an asymmetric channel. The channel walls exhibit the convective boundary conditions. In addition, the effects due to Soret and Dufour are taken into consideration. Resulting problems are solved for the series solutions. Numerical values of heat and mass transfer rates are displayed and studied. Results indicate that the concentration and temperature of the fluid increase whereas the mass transfer rate at the wall decreases with increase of the mass transfer Biot number. Furthermore, it is observed that the temperature decreases with the increase of the heat transfer Biot number. 展开更多
关键词 peristaltic transport heat and mass transfer Soret and Dufour effects convective boundary conditions
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Brownian Ratchet Driven by a Rocking Forcing with Broken Temporal Symmetry
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作者 LIUFeng-Zhi LIXiao-Wen 《Communications in Theoretical Physics》 SCIE CAS CSCD 2003年第2期173-176,共4页
The ratchet motion of a Brownian particle in a symmetric periodic potential under a rocking force thatbreaks the temporal symmetry is studied. As long as the relaxation time in the thermal background is much shorter t... The ratchet motion of a Brownian particle in a symmetric periodic potential under a rocking force thatbreaks the temporal symmetry is studied. As long as the relaxation time in the thermal background is much shorter thanthe forcing period, the unidirectional transport can be analytically treated. By solving the Fokker-Planck equations, weget an analytical expression of the current. This result indicates that with an appropriate match between the potentialfield, the asymmetric ac force and the thermal noise, a net current can be achieved. The current versus thermal noiseexhibits a stochastic-resonance-like behavior. 展开更多
关键词 Brownian ratchet directed transport stochastic resonance Fokker-Planck equation
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Generation of a Four-Particle Cluster State and Perfect Teleportation of an Arbitrary Two-Particle State in an Ion-Trap System 被引量:1
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作者 WANG Xin-Wen YANG Guo-Jian 《Communications in Theoretical Physics》 SCIE CAS CSCD 2009年第10期588-592,共5页
We propose a scheme for generating a four-particle cluster state in an ion-trap system.The scheme isinsensitive to the thermal motion of the ions,and needs less operations than previous ones.With such a setup,we alsod... We propose a scheme for generating a four-particle cluster state in an ion-trap system.The scheme isinsensitive to the thermal motion of the ions,and needs less operations than previous ones.With such a setup,we alsodemonstrate a procedure for perfectly teleporting an arbitrary two-particle state via a single multipartite entanglementchannel,a four-particle cluster state. 展开更多
关键词 cluster state TELEPORTATION ION-TRAP
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MULTI-EPIPOLAR LINES MATCHING-BASED RAY-SPACE INTERPOLATION FOR FREE VIEWPOINT VIDEO SYSTEM
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作者 Fan Liangzhong Jiang Gangyi +1 位作者 Yu Mei Yong-deak Kim 《Journal of Electronics(China)》 2008年第2期204-208,共5页
Ray-space based arbitrary viewpoint rendering without complex object segmentation or model construction is the main technology to realize Free Viewpoint Video(FVV) system for complex scenes. Ray-space interpolation an... Ray-space based arbitrary viewpoint rendering without complex object segmentation or model construction is the main technology to realize Free Viewpoint Video(FVV) system for complex scenes. Ray-space interpolation and compression are two key techniques for the solution. In this paper,correlation among multiple epipolar lines in ray-space data is analyzed,and a new method of ray-space interpolation with multi-epipolar lines matching is proposed. Comparing with the pixel-based matching interpolation method and the block-based matching interpolation method,the proposed method can achieve higher Peak Signal to Noise Ratio(PSNR) in interpolating rayspace data and rendering arbitrary viewpoint images. 展开更多
关键词 Ray-space Free Viewpoint Video (FVV) Ray-space interpolation Multi-epipolar lines matching
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AN EFFICIENT BIT RATE ALLOCATION ALGORITHM FOR MOTION JPEG2000 TRANSPORT IN TILE ENCODING
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作者 Liu Jieyu Zhang Deyun Wang Yue Li Zhe 《Journal of Electronics(China)》 2008年第2期200-203,共4页
An efficient bit rate allocation algorithm for video sequence transmission in motion JPEG2000 is presented. In many cases,the moving portions of video are often the interested regions. Based on tile encoding of JPEG20... An efficient bit rate allocation algorithm for video sequence transmission in motion JPEG2000 is presented. In many cases,the moving portions of video are often the interested regions. Based on tile encoding of JPEG2000,the important regions are discerned by two parameters. One is the complexity of a tile;the other is the motion activity of a tile. Thus an adaptive rate-allocation is re-alized in a lower complexity and the perceptive quality of a frame is improved. Experimental results show the effectiveness of this algorithm. 展开更多
关键词 Motion JPEG2000 TILE Regions-Of-Interest (ROI) Bit rate allocation
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Peristaltic transport of MHD Williamson fluid in an inclined asymmetric channel through porous medium with heat transfer 被引量:1
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作者 K.Ramesh M.Devakar 《Journal of Central South University》 SCIE EI CAS CSCD 2015年第8期3189-3201,共13页
The intention of this investigation is to study the effects of heat transfer and inclined magnetic field on the peristaltic flow of Williamson fluid in an asymmetric channel through porous medium. The governing two-di... The intention of this investigation is to study the effects of heat transfer and inclined magnetic field on the peristaltic flow of Williamson fluid in an asymmetric channel through porous medium. The governing two-dimensional equations are simplified under the assumption of long wavelength approximation. The simplified equations are solved for the stream function, temperature, and axial pressure gradient by using a regular perturbation method. The expression for pressure rise is computed numerically. The profiles of velocity, pressure gradient, temperature, heat transfer coefficient and stream function are sketched and interpreted for various embedded parameters and also the behavior of stream function for various wave forms is discussed through graphs. It is observed that the peristaltic velocity increases from porous medium to non-porous medium, the magnetic effects have increasing effect on the temperature, and the size of the trapped bolus decreases with the increasing of magnetic effects while the trend is reversed with the increasing of Darcy number. Moreover, limiting solutions of our problem are in close agreement with the corresponding results of the Newtonian fluid model. 展开更多
关键词 Williamson fluid heat transfer inclined magnetic field porous medium inclined asymmetric channel
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Simulation of Near-Fault Strong Ground Motion in the Beijing Region
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作者 Pan Bo Xu Jiandong +1 位作者 Haruko Sekigguchi He Honglin 《Earthquake Research in China》 2007年第3期281-292,共12页
On the basis of previous study of the 1679 Sanhe-Pinggu(M8.0) earthquake,the biggest event in history ever recorded in Beijing and its adjacent area,we made a 3-D strong ground motion simulation utilizing the staggere... On the basis of previous study of the 1679 Sanhe-Pinggu(M8.0) earthquake,the biggest event in history ever recorded in Beijing and its adjacent area,we made a 3-D strong ground motion simulation utilizing the staggered-grid finite differences method to study the distributions of peak ground velocity with different earthquake source models in the Beijing region.In the paper,earthquake source models and a transmission medium velocity model are established and the corresponding parameters are given in accordance to the results from a related previous study.Then,using a three-dimensional finite difference computing program of near-fault strong ground motion developed by Graves,the peak ground velocity caused by a destructive earthquake in the Beijing area is simulated.In our computation model,the earthquake source is 3km in depth,and a total number of 21,679 observation points on the ground surface are figured out.The transmission medium velocity model is composed of four stratums which are the Quaternary deposit,the upper crust,the upper part of the middle crust and the lower part of the middle crust.With the minimum grid spacing of 0.15km,a total of 2.28×106 grids are generated.Using a time step of 0.02 seconds we calculated the peak ground velocity for a duration of 8 seconds.After the analysis of the simulation results,we observed some basic characteristics of near-fault strong ground motion such as the concentration effect of near-fault peak ground velocity,rupture directivity effect,hanging wall effect,and basin effect.The results from our simulation and analysis suggest that the source and transmitting medium parameters in our model are suitable and the finite difference method is applicable to estimate the distribution of strong ground motion in the study region. 展开更多
关键词 Strong ground motion Source parameter Transmitting medium parameter Concentration effect Rupture directivity effect Hanging wall effect basin effect
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Effect of Force Adaptation in Mechanics
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作者 Konstantin Samson Ivanov 《Journal of Mechanics Engineering and Automation》 2011年第3期163-180,共18页
Discovery of effect of force adaptation in mechanics is presented. The discovery is based on use of the mobile closed mechanical contour for force transfer from the mechanism input link to an output link, According to... Discovery of effect of force adaptation in mechanics is presented. The discovery is based on use of the mobile closed mechanical contour for force transfer from the mechanism input link to an output link, According to discovery the motion transfer can be carried out by Assur structural group in the form of the mobile closed contour, and the output link is the link with one degree of freedom. The received mechanical system includes an input link, an output link and the closed contour placed between them as fourth class Assur structural group. The kinematic chain has two degrees of freedom. However the closed contour imposes an additional constraint on relative motion of its links. The carried out discovery allows providing the variable transfer ratio only due to the variable external load. Mechanical properties of the closed contour allow providing the required transfer ratio independently, smart and automatically. 展开更多
关键词 Force adaptation closed contour constraint.
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优异性能来自嵌入式设计 新型E4/4-轻型拖链:轻量、安静及更稳定
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《国内外机电一体化技术》 2005年第6期90-90,共1页
无论是在经常的短行程高速运行或其它各种情况下,能量的运动传输和保护都需确保其高效和稳定性。此时,用户就需要一个既轻量又稳定的柔性能量供应系统。例如:对于机床,填充物重量在逐渐增加,悬空使用时需要更好的导向。为了满足这... 无论是在经常的短行程高速运行或其它各种情况下,能量的运动传输和保护都需确保其高效和稳定性。此时,用户就需要一个既轻量又稳定的柔性能量供应系统。例如:对于机床,填充物重量在逐渐增加,悬空使用时需要更好的导向。为了满足这些不胜枚举的实际应用,易格斯(igus)公司新近开发了一款新的拖链系统——E4/4-轻型拖链系统。它是一个薄壁和紧凑设计的新系统。E4/4-轻型的推出填补了易格斯产品系列中E4/4系统(高稳定性)和E4-轻型(高轻量)之间的产品空白。 展开更多
关键词 E4/4-轻型拖链 嵌入式设计 运动传输 稳定性 安装空间
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Peristaltic transport of hydromagnetic Jeffrey fluid with temperature-dependent viscosity and thermal conductivity
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作者 Q. Hussain S. Asghar +1 位作者 T. Hayat A. Alsaedi 《International Journal of Biomathematics》 2016年第2期199-220,共22页
In this paper, we investigate the effects of variable viscosity and thermal conductivity on peristaltic flow of Jeffrey fluid in an asymmetric channel. The inclined magnetic field, viscous dissipation and Joule heatin... In this paper, we investigate the effects of variable viscosity and thermal conductivity on peristaltic flow of Jeffrey fluid in an asymmetric channel. The inclined magnetic field, viscous dissipation and Joule heating are also considered. Wave frame and long wave-length approximations are made to formulate the problem. Pressure gradient, pressure drop per wavelength, velocity and temperature profiles are calculated analytically and discussed graphically. Comparison is made with the previous work for reliability. 展开更多
关键词 Peristaltic flow inclined magnetic field temperature-dependent properties Joule heating.
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