目的利用速度向量成像技术(velocity vector imaging,VVI)分析慢性肾小球肾炎(chronic glomerulonephritis,CGN)患者左心房功能和储备期运动同步性改变及两者相关性。方法选取2020年12月至2021年7月在南京市中医院经胸心脏超声检查的52...目的利用速度向量成像技术(velocity vector imaging,VVI)分析慢性肾小球肾炎(chronic glomerulonephritis,CGN)患者左心房功能和储备期运动同步性改变及两者相关性。方法选取2020年12月至2021年7月在南京市中医院经胸心脏超声检查的52例CGN患者,分为A组(n=26,2~3期)和B组(n=26,4~5期),另选取健康志愿者50名为C组(对照组),采用VVI获得左心房功能指标和储备期运动同步性指标,比较三组各项指标的差异并分析两者的相关性。结果①三组除血肌酐、收缩压(systolic blood pressure,SBP)比较差异有统计学意义(P<0.05)外,余一般临床资料比较差异无统计学意义(P>0.05);②三组的左心房功能指标比较差异有统计学意义(P<0.05);③三组的左心房顶部峰值时间(peak time of left atrial roof,TP-LAR)比较差异无统计学意义(P>0.05),三组的平均左心房侧壁峰值时间(peak time of left atrial lateral wall,TP-LALW)、房间隔峰值时间(peak time of atrial septum,TP-AS)、任意两节段应变率最大峰值时间差(maximum peak time difference of strain rate of any two segments,TSR-MAX)比较,差异有统计学意义(P<0.05);④收缩期峰值应变率(peak systolic strain rate,SRS)、舒张早期峰值应变率(early diastolic peak strain rate,SRE)、舒张末期峰值应变率(late diastolic peak strain rate,SRA)与mTP-LALW、mTP-AS、mTSR-MAX呈负相关(P<0.05),与mTP-LAR无相关性(P>0.05)。结论CGN患者左心房的储存、通道和泵血功能随肾功能不全进展减低;左心房储备期mTP-LALW、mTP-AS及mTSR-MAX随肾功能不全进展增加,存在左房运动非同步性;左房功能与储备期运动同步性具有相关性,左房功能损害伴随着电传导异常。展开更多
To realize the data synchronization between the inertial measurement unit （IMU） and the global positioning system （GPS）, the synchronization technology in the IMU/GPS integrated measurement system of vehicle motio...To realize the data synchronization between the inertial measurement unit （IMU） and the global positioning system （GPS）, the synchronization technology in the IMU/GPS integrated measurement system of vehicle motion parameters is studied. According to the characteristics of the output signals of the IMU and the GPS, without the IMU synchronization signal, the synchronization circuit based on CPLD is designed and developed, which need not alter the configurations of the IMU and GPS. Experiments of measuring vehicle motion parameters, which rely on the synchronization circuit to realize IMU/GPS data synchronization, are made. The driving routes in experiments comprise a curve and a straight line. Experimental results show that the designed circuit can accurately measure the synchronization time difference and the IMU period, and can effectively solve the data synchronization in IMU/GPS integration. Furthermore, the IMU/GPS integrated measurement system based on the synchronization circuit can measure and calculate many vehicle motion parameters in high frequency mode.展开更多
AIM:To compare the demographic and clinical features of different manometric subsets of ineffective oesophageal motility(IOM;defined as ≥ 30% wet swallows with distal contractile amplitude < 30 mmHg) ,and to deter...AIM:To compare the demographic and clinical features of different manometric subsets of ineffective oesophageal motility(IOM;defined as ≥ 30% wet swallows with distal contractile amplitude < 30 mmHg) ,and to determine whether the prevalence of gastro-oesophageal reflux differs between IOM subsets. METHODS:Clinical characteristics of manometric subsets were determined in 100 IOM patients(73 female,median age 58 years) and compared to those of 100 age-and gender-matched patient controls with oesophageal symptoms,but normal manometry. Supine oesophageal manometry was performed with an eight-channel DentSleeve water-perfused catheter,and an ambulatory pH study assessed gastro-oesophageal reflux. RESULTS:Patients in the IOM subset featuring a majority of low-amplitude simultaneous contractions(LASC) experienced less heartburn(prevalence 26%) ,but more dysphagia(57%) than those in the IOM subset featuring low-amplitude propagated contractions(LAP;heartburn 70%,dysphagia 24%;both P ≤ 0.01) . LASC patients also experienced less heartburn and more dysphagia than patient controls(heartburn 68%,dysphagia 11%;both P < 0.001) . The prevalence of heartburn and dysphagia in IOM patients featuring a majority of non-transmitted sequences(NT) was 54%(P = 0.04 vs LASC) and 36%(P < 0.01 vs controls) ,respectively. No differences inage and gender distribution,chest pain prevalence,acid exposure time(AET) and symptom/reflux association existed between IOM subsets,or between subsets and controls. CONCLUSION:IOM patients with LASC exhibit a different symptom profile to those with LAP,but do not differ in gastro-oesophageal reflux prevalence. These findings raise the possibility of different pathophysiological mechanisms in IOM subsets,which warrants further investigation.展开更多
文摘目的利用速度向量成像技术(velocity vector imaging,VVI)分析慢性肾小球肾炎(chronic glomerulonephritis,CGN)患者左心房功能和储备期运动同步性改变及两者相关性。方法选取2020年12月至2021年7月在南京市中医院经胸心脏超声检查的52例CGN患者,分为A组(n=26,2~3期)和B组(n=26,4~5期),另选取健康志愿者50名为C组(对照组),采用VVI获得左心房功能指标和储备期运动同步性指标,比较三组各项指标的差异并分析两者的相关性。结果①三组除血肌酐、收缩压(systolic blood pressure,SBP)比较差异有统计学意义(P<0.05)外,余一般临床资料比较差异无统计学意义(P>0.05);②三组的左心房功能指标比较差异有统计学意义(P<0.05);③三组的左心房顶部峰值时间(peak time of left atrial roof,TP-LAR)比较差异无统计学意义(P>0.05),三组的平均左心房侧壁峰值时间(peak time of left atrial lateral wall,TP-LALW)、房间隔峰值时间(peak time of atrial septum,TP-AS)、任意两节段应变率最大峰值时间差(maximum peak time difference of strain rate of any two segments,TSR-MAX)比较,差异有统计学意义(P<0.05);④收缩期峰值应变率(peak systolic strain rate,SRS)、舒张早期峰值应变率(early diastolic peak strain rate,SRE)、舒张末期峰值应变率(late diastolic peak strain rate,SRA)与mTP-LALW、mTP-AS、mTSR-MAX呈负相关(P<0.05),与mTP-LAR无相关性(P>0.05)。结论CGN患者左心房的储存、通道和泵血功能随肾功能不全进展减低;左心房储备期mTP-LALW、mTP-AS及mTSR-MAX随肾功能不全进展增加,存在左房运动非同步性;左房功能与储备期运动同步性具有相关性,左房功能损害伴随着电传导异常。
文摘To realize the data synchronization between the inertial measurement unit （IMU） and the global positioning system （GPS）, the synchronization technology in the IMU/GPS integrated measurement system of vehicle motion parameters is studied. According to the characteristics of the output signals of the IMU and the GPS, without the IMU synchronization signal, the synchronization circuit based on CPLD is designed and developed, which need not alter the configurations of the IMU and GPS. Experiments of measuring vehicle motion parameters, which rely on the synchronization circuit to realize IMU/GPS data synchronization, are made. The driving routes in experiments comprise a curve and a straight line. Experimental results show that the designed circuit can accurately measure the synchronization time difference and the IMU period, and can effectively solve the data synchronization in IMU/GPS integration. Furthermore, the IMU/GPS integrated measurement system based on the synchronization circuit can measure and calculate many vehicle motion parameters in high frequency mode.
文摘AIM:To compare the demographic and clinical features of different manometric subsets of ineffective oesophageal motility(IOM;defined as ≥ 30% wet swallows with distal contractile amplitude < 30 mmHg) ,and to determine whether the prevalence of gastro-oesophageal reflux differs between IOM subsets. METHODS:Clinical characteristics of manometric subsets were determined in 100 IOM patients(73 female,median age 58 years) and compared to those of 100 age-and gender-matched patient controls with oesophageal symptoms,but normal manometry. Supine oesophageal manometry was performed with an eight-channel DentSleeve water-perfused catheter,and an ambulatory pH study assessed gastro-oesophageal reflux. RESULTS:Patients in the IOM subset featuring a majority of low-amplitude simultaneous contractions(LASC) experienced less heartburn(prevalence 26%) ,but more dysphagia(57%) than those in the IOM subset featuring low-amplitude propagated contractions(LAP;heartburn 70%,dysphagia 24%;both P ≤ 0.01) . LASC patients also experienced less heartburn and more dysphagia than patient controls(heartburn 68%,dysphagia 11%;both P < 0.001) . The prevalence of heartburn and dysphagia in IOM patients featuring a majority of non-transmitted sequences(NT) was 54%(P = 0.04 vs LASC) and 36%(P < 0.01 vs controls) ,respectively. No differences inage and gender distribution,chest pain prevalence,acid exposure time(AET) and symptom/reflux association existed between IOM subsets,or between subsets and controls. CONCLUSION:IOM patients with LASC exhibit a different symptom profile to those with LAP,but do not differ in gastro-oesophageal reflux prevalence. These findings raise the possibility of different pathophysiological mechanisms in IOM subsets,which warrants further investigation.
