目的观察运脾益肾中药及营养、运动、穴位按摩、器械训练和运动体操等综合干预治疗学龄期特发性矮小症(idiopathic short stature,ISS)的疗效。方法将确诊为ISS的95例学龄期ISS患儿随机分为两组:治疗组给予运脾益肾中药及营养、运动、...目的观察运脾益肾中药及营养、运动、穴位按摩、器械训练和运动体操等综合干预治疗学龄期特发性矮小症(idiopathic short stature,ISS)的疗效。方法将确诊为ISS的95例学龄期ISS患儿随机分为两组:治疗组给予运脾益肾中药及营养、运动、穴位按摩、器械训练和运动体操等综合干预治疗;对照组给予重组人生长激素皮下注射,两组患儿干预及治疗时间均为12个月。分别于治疗前、治疗后6个月、12个月测定患儿身高、体重和骨龄,并计算年骨龄变化量。结果两组治疗6个月后身高比较差异无统计学意义(P>0.05):治疗组(125.3±7.2)cm、对照组(126.7±7.2)cm;治疗12个月后身高比较差异无统计学意义(P>0.05):治疗组(130.1±7.1)cm、对照组(130.3±6.8)cm。两组在治疗12个月之中,前6个月身高增长量治疗组落后于对照组,后6个月身高增长量治疗组优于对照组,差异均有统计学意义(P<0.05);两组身高年增长量无显著性差异;两组年骨龄变化量无显著性差异;两组体重增加治疗组大于对照组,差异均有统计学意义(P<0.05),但未出现肥胖儿,治疗组体重更接近于同年龄同性别平均值,对照组体重仍落后于同年龄同性别平均值。结论综合干预在ISS治疗中疗效显著,且无不良反应,价格相对较低,在ISS患儿的治疗中值得推广。展开更多
Objective To observe the clinical efficacy of pediatric Tuina(Chinese therapeutic massage)plus oral administration of Chinese medication for pediatric anorexia due to spleen failing in transportation.Methods A total o...Objective To observe the clinical efficacy of pediatric Tuina(Chinese therapeutic massage)plus oral administration of Chinese medication for pediatric anorexia due to spleen failing in transportation.Methods A total of 94 children with anorexia due to spleen failing in transportation were randomized into an observation group and a control group by the random number table method at a ratio of 1:1,with 47 cases in each group.The control group was treated with modified Bu Huan Jin Zheng Qi San,and the observation group was treated with additional Tuina manipulation of Yun Shui Ru Tu based on the treatment in the control group.After 4 weeks of treatment,the clinical efficacy of the two groups was observed,and the traditional Chinese medicine(TCM)symptom score,serum leptin,neuropeptide Y,and serum zinc and calcium levels were compared.Results After 4 weeks of treatment,the total effective rate of the observation group was 87.2%,and that of the control group was 74.5%.The difference between the two groups was statistically significant( P<0.05).After treatment,the TCM symptom scores in both groups decreased significantly(P<0.05),and the scores in the observation group were lower than those in the control group(P<0.05).After treatment,the serum leptin level in both groups decreased,and the level in the observation group was lower than that in the control group(P<0.05).The serum neuropeptide Y,zinc,and calcium levels in both groups increased after treatment,and the levels in the observation group were higher than those in the control group(P<0.05).Conclusion Tuina manipulation of Yun Shui Ru Tu plus oral administration of Chinese medication is significantly effective in treating pediatric anorexia due to spleen failing in transportation,which can improve the appetite of children and improve the symptoms of anorexia,and the curative effect is better than that of oral administration of Chinese medication alone.展开更多
文摘目的观察运脾益肾中药及营养、运动、穴位按摩、器械训练和运动体操等综合干预治疗学龄期特发性矮小症(idiopathic short stature,ISS)的疗效。方法将确诊为ISS的95例学龄期ISS患儿随机分为两组:治疗组给予运脾益肾中药及营养、运动、穴位按摩、器械训练和运动体操等综合干预治疗;对照组给予重组人生长激素皮下注射,两组患儿干预及治疗时间均为12个月。分别于治疗前、治疗后6个月、12个月测定患儿身高、体重和骨龄,并计算年骨龄变化量。结果两组治疗6个月后身高比较差异无统计学意义(P>0.05):治疗组(125.3±7.2)cm、对照组(126.7±7.2)cm;治疗12个月后身高比较差异无统计学意义(P>0.05):治疗组(130.1±7.1)cm、对照组(130.3±6.8)cm。两组在治疗12个月之中,前6个月身高增长量治疗组落后于对照组,后6个月身高增长量治疗组优于对照组,差异均有统计学意义(P<0.05);两组身高年增长量无显著性差异;两组年骨龄变化量无显著性差异;两组体重增加治疗组大于对照组,差异均有统计学意义(P<0.05),但未出现肥胖儿,治疗组体重更接近于同年龄同性别平均值,对照组体重仍落后于同年龄同性别平均值。结论综合干预在ISS治疗中疗效显著,且无不良反应,价格相对较低,在ISS患儿的治疗中值得推广。
文摘Objective To observe the clinical efficacy of pediatric Tuina(Chinese therapeutic massage)plus oral administration of Chinese medication for pediatric anorexia due to spleen failing in transportation.Methods A total of 94 children with anorexia due to spleen failing in transportation were randomized into an observation group and a control group by the random number table method at a ratio of 1:1,with 47 cases in each group.The control group was treated with modified Bu Huan Jin Zheng Qi San,and the observation group was treated with additional Tuina manipulation of Yun Shui Ru Tu based on the treatment in the control group.After 4 weeks of treatment,the clinical efficacy of the two groups was observed,and the traditional Chinese medicine(TCM)symptom score,serum leptin,neuropeptide Y,and serum zinc and calcium levels were compared.Results After 4 weeks of treatment,the total effective rate of the observation group was 87.2%,and that of the control group was 74.5%.The difference between the two groups was statistically significant( P<0.05).After treatment,the TCM symptom scores in both groups decreased significantly(P<0.05),and the scores in the observation group were lower than those in the control group(P<0.05).After treatment,the serum leptin level in both groups decreased,and the level in the observation group was lower than that in the control group(P<0.05).The serum neuropeptide Y,zinc,and calcium levels in both groups increased after treatment,and the levels in the observation group were higher than those in the control group(P<0.05).Conclusion Tuina manipulation of Yun Shui Ru Tu plus oral administration of Chinese medication is significantly effective in treating pediatric anorexia due to spleen failing in transportation,which can improve the appetite of children and improve the symptoms of anorexia,and the curative effect is better than that of oral administration of Chinese medication alone.
