We analyzed the infrared 0R）-near infrared （NIR） 2D correlation spectra of drugs perturbed by temperature. By identification of functional groups by IR spectrum and by the correlation analysis of IR-NIR spectrum, w...We analyzed the infrared 0R）-near infrared （NIR） 2D correlation spectra of drugs perturbed by temperature. By identification of functional groups by IR spectrum and by the correlation analysis of IR-NIR spectrum, we identified the characteristic spectral bands that were closely related to the structure of a drug substance of interest. These characteristic spectral bands were relatively less interfered by other ingredients for analysis by the NIR correlation coefficient method. With these characteristic spectral bands, the accuracy of screening illegally added Sildenafil citrate, Tadalafil and Metforrnin hydrochloride in Chinese patent drugs and healthcare products reached about 90%, which met the requirements of rapid screening.展开更多
Chang’E-1(CE-1)Interference Imaging Spectrometer(IIM)dataset suffers from the weak response in the near infrared(NIR)bands,which are the important wavelength for retrieving the minerals and elements of the Moon.In th...Chang’E-1(CE-1)Interference Imaging Spectrometer(IIM)dataset suffers from the weak response in the near infrared(NIR)bands,which are the important wavelength for retrieving the minerals and elements of the Moon.In this paper,the cross-calibration was implemented to the IIM hyperspectral data for improving the weak response in NIR bands.The results show that the cross-calibrated IIM spectra were consistent to the Earth-based telescopic spectra,which suggests that the cross-calibration yields acceptable results.For further validating the influence of the cross-calibration on the FeO inversion and searching the optimal bands to retrieve lunar FeO contents,four band selection schemes were designed to retrieve FeO using the original and cross-calibrated IIM spectra.By comparing the distribution patterns and histograms of the IIM derived FeO contents with the Clementine derived FeO,the IIM 891 nm band after cross-calibration showed a higher accuracy in the FeO inversion,hence most useful for lunar FeO inversion.展开更多
基金National Key Technology R & D Program-On-site Rapid Identification of Drug Research Project (Grant No. 2008BAI55B06)
文摘We analyzed the infrared 0R）-near infrared （NIR） 2D correlation spectra of drugs perturbed by temperature. By identification of functional groups by IR spectrum and by the correlation analysis of IR-NIR spectrum, we identified the characteristic spectral bands that were closely related to the structure of a drug substance of interest. These characteristic spectral bands were relatively less interfered by other ingredients for analysis by the NIR correlation coefficient method. With these characteristic spectral bands, the accuracy of screening illegally added Sildenafil citrate, Tadalafil and Metforrnin hydrochloride in Chinese patent drugs and healthcare products reached about 90%, which met the requirements of rapid screening.
基金supported by the National Basic Research Program of China (Grant No. 2010CB951603)Shanghai Science and Technology Support Program Special for EXPO (Grant No. 10DZ0581600)+2 种基金the Open Research Funding Program of KLGIS (Grant No. KLGIS2011A09)the National Natural Science Foundation of China (Grant No. 41172296)the Program for New Century Excellent Talents in University (Grant No. NCET-11-0242)
文摘Chang’E-1(CE-1)Interference Imaging Spectrometer(IIM)dataset suffers from the weak response in the near infrared(NIR)bands,which are the important wavelength for retrieving the minerals and elements of the Moon.In this paper,the cross-calibration was implemented to the IIM hyperspectral data for improving the weak response in NIR bands.The results show that the cross-calibrated IIM spectra were consistent to the Earth-based telescopic spectra,which suggests that the cross-calibration yields acceptable results.For further validating the influence of the cross-calibration on the FeO inversion and searching the optimal bands to retrieve lunar FeO contents,four band selection schemes were designed to retrieve FeO using the original and cross-calibrated IIM spectra.By comparing the distribution patterns and histograms of the IIM derived FeO contents with the Clementine derived FeO,the IIM 891 nm band after cross-calibration showed a higher accuracy in the FeO inversion,hence most useful for lunar FeO inversion.
