Two protected single amino acid chelates,N~α-Fmoc-N~ε,N~ε-di((2,2-dimethyl-1,3-dithian-5-yl)methyl)-L-lysine(7) and N~α-Fmoc-N~ε-(2,2-dimethyl-1,3-dithian-5-yl)methyl,N~ε-Boc-L-lysine(9),were synthesized by modi...Two protected single amino acid chelates,N~α-Fmoc-N~ε,N~ε-di((2,2-dimethyl-1,3-dithian-5-yl)methyl)-L-lysine(7) and N~α-Fmoc-N~ε-(2,2-dimethyl-1,3-dithian-5-yl)methyl,N~ε-Boc-L-lysine(9),were synthesized by modifying the side chain of lysine with 1,3-dithiane through direct reductive N-alkylation protocol.These amino acids have potential uses in peptide chemistry.展开更多
文摘Two protected single amino acid chelates,N~α-Fmoc-N~ε,N~ε-di((2,2-dimethyl-1,3-dithian-5-yl)methyl)-L-lysine(7) and N~α-Fmoc-N~ε-(2,2-dimethyl-1,3-dithian-5-yl)methyl,N~ε-Boc-L-lysine(9),were synthesized by modifying the side chain of lysine with 1,3-dithiane through direct reductive N-alkylation protocol.These amino acids have potential uses in peptide chemistry.
