Locally recurrent rectal cancer(LRRC) is a complex disease with far-reaching implications for the patient. Until recently, research was limited regarding surgical techniques that can increase the ability to perform an...Locally recurrent rectal cancer(LRRC) is a complex disease with far-reaching implications for the patient. Until recently, research was limited regarding surgical techniques that can increase the ability to perform an en bloc resection with negative margins. This has changed in recent years and therefore outcomes for these patients have improved. Novel radical techniques and adjuncts allow for more radical resections thereby improving the chance of negative resection margins and outcomes. In the past contraindications to surgery included anterior involvement of the pubic bone, sacral invasions above the level of S2/S3 and lateral pelvic wall involvement. However, current data suggests that previously unresectable cases may now be feasible with novel techniques, surgical approaches and reconstructive surgery. The publications to date have only reported small patient pools with the research conducted by highly specialised units. Moreover, the short and long-term oncological outcomes are currently under review. Therefore although surgical options for LRRC have expanded significantly, one should balance the treatment choices available against the morbidity associated with the procedure and select the right patient for it.展开更多
Extended pelvic side wall excision is a useful technique for treatment of recurrent or advanced rectal cancer involving sciatic notch and does not compromise the dissection of major pelvic vessels and vascular control.
Patterns of brachiopod paleobiogeographic regionalization in Central Asia reveal a coevolution between brachiopod paleobiogeography and tectonopaleogeography during the Early Devonian,Early Carboniferous,Late Carbonif...Patterns of brachiopod paleobiogeographic regionalization in Central Asia reveal a coevolution between brachiopod paleobiogeography and tectonopaleogeography during the Early Devonian,Early Carboniferous,Late Carboniferous,Early Permian,and Middle Permian.The coevolutionary relationship reasonably accounts for the formation mechanisms of brachiopod paleobiogeography in this region,and also provides a basis for studies on the location and configuration of oceans and plates(blocks)during the late Paleozoic in Central Asia.展开更多
The Yanshan Basin,located in northern North China,underwent three primary stages in the Mesoproterozoic,and corresponding biotas have been summarized for each stage in the present study.The three stages are stage A(th...The Yanshan Basin,located in northern North China,underwent three primary stages in the Mesoproterozoic,and corresponding biotas have been summarized for each stage in the present study.The three stages are stage A(the lower part of the Changcheng Group which dominated by clastic sediments),stage B(the upper part of the Changcheng Group to the Jixian Group which characterized by carbonate sediments),and stage C(the upper part of the Jixian Group which dominated by clastic sediments).This paper will focus on the evolution of biota during stage B.Microbiota of the stage B exhibits a high level of diversity and abundance.Planktonic microfossils have various forms and complex decorations.Most microfossils are small.In stage B,there was great variation in the biotic abundance and diversity,the average diameter of spherical benthic microfossils,and the maximum diameter of the spherical microfossils.We analyzed these parameters and identified two typical biotic events,and both biotic events were corresponded with geological events.The first event occurred in the third member of the Dahongyu Formation.In this era,the maximum diameter of the silicified microfossils significantly increased,and large,spherical planktonic specimens are abundant.The flourishing of large organisms in the strata is presumably related to volcanic activity.The second event occurred in the third member of the Gaoyuzhuang Formation.During this era,the microfossil assemblage changed significantly.The changes correspond with a decline in stromatolites as well as the transformations of the carbon isotope ratios and the elemental geochemistry.展开更多
Fluvial terraces are important geomorphic markers for modern valley development.When coupled with numeric ages,terraces can provide abundant information about tectonic,climatic,paleohydrological and the paleoenvironme...Fluvial terraces are important geomorphic markers for modern valley development.When coupled with numeric ages,terraces can provide abundant information about tectonic,climatic,paleohydrological and the paleoenvironmental changes.On the basis of the paleomagnetic,electron spin resonance(ESR) and optically stimulated luminescence(OSL) dating,in addition to an investigation of local loess-paleosol sequences,we confirmed that 13 fluvial terraces were formed,and then preserved,along the course of the Upper Weihe River in the Sanyangchuan Basin over the past 1.2 Ma.Analyses of the characteristics and genesis of these terraces indicate that they resulted from the response of this particular river system to climate change over an orbital scale.These changes can further be placed within the context of local and regional tectonic uplift,and represent an alternation between lateral migration and vertical incision,dependent upon the predominance of climatic and tectonic controls during different periods.Most of the terraces are strikingly similar in that they have several meters of paleosols which have developed directly on top of fluvial deposits located on the terrace treads,suggesting that the abandonment of terraces due to river incision occurred during the transitions from glacial to interglacial climates.The temporal and spatial differences in the distribution patterns of terraces located on either side of the river valley indicate that a tectonic inversion occurred in Sanyangchuan Basin at-0.62 Ma,and that this was characterized by a transition from overall uplift to depression induced by fault activity.Synthesized studies of the Basin's terraces indicate that formation of the modern valley of the Upper Weihe River may have begun in the late Early Pleistocene between1.4-1.2 Ma.展开更多
文摘Locally recurrent rectal cancer(LRRC) is a complex disease with far-reaching implications for the patient. Until recently, research was limited regarding surgical techniques that can increase the ability to perform an en bloc resection with negative margins. This has changed in recent years and therefore outcomes for these patients have improved. Novel radical techniques and adjuncts allow for more radical resections thereby improving the chance of negative resection margins and outcomes. In the past contraindications to surgery included anterior involvement of the pubic bone, sacral invasions above the level of S2/S3 and lateral pelvic wall involvement. However, current data suggests that previously unresectable cases may now be feasible with novel techniques, surgical approaches and reconstructive surgery. The publications to date have only reported small patient pools with the research conducted by highly specialised units. Moreover, the short and long-term oncological outcomes are currently under review. Therefore although surgical options for LRRC have expanded significantly, one should balance the treatment choices available against the morbidity associated with the procedure and select the right patient for it.
文摘Extended pelvic side wall excision is a useful technique for treatment of recurrent or advanced rectal cancer involving sciatic notch and does not compromise the dissection of major pelvic vessels and vascular control.
基金supported by Project of China Geological Survey(Grant No.1212011120153-3)
文摘Patterns of brachiopod paleobiogeographic regionalization in Central Asia reveal a coevolution between brachiopod paleobiogeography and tectonopaleogeography during the Early Devonian,Early Carboniferous,Late Carboniferous,Early Permian,and Middle Permian.The coevolutionary relationship reasonably accounts for the formation mechanisms of brachiopod paleobiogeography in this region,and also provides a basis for studies on the location and configuration of oceans and plates(blocks)during the late Paleozoic in Central Asia.
基金supported by National Basic Research Program of China (Grant No. 2011CB808800)National Natural Science Foundation of China (Grant No. 41272015)
文摘The Yanshan Basin,located in northern North China,underwent three primary stages in the Mesoproterozoic,and corresponding biotas have been summarized for each stage in the present study.The three stages are stage A(the lower part of the Changcheng Group which dominated by clastic sediments),stage B(the upper part of the Changcheng Group to the Jixian Group which characterized by carbonate sediments),and stage C(the upper part of the Jixian Group which dominated by clastic sediments).This paper will focus on the evolution of biota during stage B.Microbiota of the stage B exhibits a high level of diversity and abundance.Planktonic microfossils have various forms and complex decorations.Most microfossils are small.In stage B,there was great variation in the biotic abundance and diversity,the average diameter of spherical benthic microfossils,and the maximum diameter of the spherical microfossils.We analyzed these parameters and identified two typical biotic events,and both biotic events were corresponded with geological events.The first event occurred in the third member of the Dahongyu Formation.In this era,the maximum diameter of the silicified microfossils significantly increased,and large,spherical planktonic specimens are abundant.The flourishing of large organisms in the strata is presumably related to volcanic activity.The second event occurred in the third member of the Gaoyuzhuang Formation.During this era,the microfossil assemblage changed significantly.The changes correspond with a decline in stromatolites as well as the transformations of the carbon isotope ratios and the elemental geochemistry.
基金supported by the National Natural Science Foundation of China(Grant Nos.41471008,91125008 and 41330745the Fundamental Research Funds for the Central Universities(Grant No.LZUJBKY-2016-161).
文摘Fluvial terraces are important geomorphic markers for modern valley development.When coupled with numeric ages,terraces can provide abundant information about tectonic,climatic,paleohydrological and the paleoenvironmental changes.On the basis of the paleomagnetic,electron spin resonance(ESR) and optically stimulated luminescence(OSL) dating,in addition to an investigation of local loess-paleosol sequences,we confirmed that 13 fluvial terraces were formed,and then preserved,along the course of the Upper Weihe River in the Sanyangchuan Basin over the past 1.2 Ma.Analyses of the characteristics and genesis of these terraces indicate that they resulted from the response of this particular river system to climate change over an orbital scale.These changes can further be placed within the context of local and regional tectonic uplift,and represent an alternation between lateral migration and vertical incision,dependent upon the predominance of climatic and tectonic controls during different periods.Most of the terraces are strikingly similar in that they have several meters of paleosols which have developed directly on top of fluvial deposits located on the terrace treads,suggesting that the abandonment of terraces due to river incision occurred during the transitions from glacial to interglacial climates.The temporal and spatial differences in the distribution patterns of terraces located on either side of the river valley indicate that a tectonic inversion occurred in Sanyangchuan Basin at-0.62 Ma,and that this was characterized by a transition from overall uplift to depression induced by fault activity.Synthesized studies of the Basin's terraces indicate that formation of the modern valley of the Upper Weihe River may have begun in the late Early Pleistocene between1.4-1.2 Ma.