The presence of cystic fibrosis (CF)-related diabetes was evaluated in 19 adolescents with CF by continuous glucose monitoring system (CGMS) and oral glucose tolerance testing. CGMS confirmed diabetic glucose excursio...The presence of cystic fibrosis (CF)-related diabetes was evaluated in 19 adolescents with CF by continuous glucose monitoring system (CGMS) and oral glucose tolerance testing. CGMS confirmed diabetic glucose excursions in 7/19 subjects deemed diabetic on oral glucose tolerance testing. CGMS is a useful tool for detecting hyperglycemia in CF.展开更多
妊娠期糖尿病(gestational diabetes mellitus,GDM)是指妊娠期发生的不同程度的糖耐量异常,不包括妊娠前已存在的糖尿病,是一种常见的妊娠期并发症[1,2]。孕期胎盘分泌产生的人胎盘催乳素、胎盘胰岛素酶,尤其肿瘤坏死因子等物质...妊娠期糖尿病(gestational diabetes mellitus,GDM)是指妊娠期发生的不同程度的糖耐量异常,不包括妊娠前已存在的糖尿病,是一种常见的妊娠期并发症[1,2]。孕期胎盘分泌产生的人胎盘催乳素、胎盘胰岛素酶,尤其肿瘤坏死因子等物质均可拮抗胰岛素的降糖作用,随着妊娠周数增加,拮抗胰岛素作用增强,若孕前即存在胰岛素分泌受限情况,或孕期无法代偿这一作用,则会出现 GDM。因妊娠期母体需消耗葡萄糖为胎儿提供能量,以及母体肾血流量及肾小球滤过率增加从而导致经尿液排出葡萄糖增多等原因,妊娠期女性血糖水平较非孕期下降。肖温温等通过测定正常孕妇早、中、晚孕期空腹血糖水平,发现结果均低于正常非孕妇女[3]。通过高血糖与妊娠不良结局(the hyperglycemia and adverse pregnancy outcome study,HAPO)的流行病学研究[4,5],美国糖尿病协会(American Diabetes Association,ADA)与国际妊娠合并糖尿病研究组织(International Association of diabetes and pregnancy study groups,IADPSG)推荐GDM 诊断新标准,见本期相关内容[6]。孕期将孕前糖尿病以及 GDM 孕妇血糖控制在妊娠期正常水平至关重要,在临床工作中主要有以下几种监测孕妇血糖水平的方法。展开更多
文摘The presence of cystic fibrosis (CF)-related diabetes was evaluated in 19 adolescents with CF by continuous glucose monitoring system (CGMS) and oral glucose tolerance testing. CGMS confirmed diabetic glucose excursions in 7/19 subjects deemed diabetic on oral glucose tolerance testing. CGMS is a useful tool for detecting hyperglycemia in CF.
文摘妊娠期糖尿病(gestational diabetes mellitus,GDM)是指妊娠期发生的不同程度的糖耐量异常,不包括妊娠前已存在的糖尿病,是一种常见的妊娠期并发症[1,2]。孕期胎盘分泌产生的人胎盘催乳素、胎盘胰岛素酶,尤其肿瘤坏死因子等物质均可拮抗胰岛素的降糖作用,随着妊娠周数增加,拮抗胰岛素作用增强,若孕前即存在胰岛素分泌受限情况,或孕期无法代偿这一作用,则会出现 GDM。因妊娠期母体需消耗葡萄糖为胎儿提供能量,以及母体肾血流量及肾小球滤过率增加从而导致经尿液排出葡萄糖增多等原因,妊娠期女性血糖水平较非孕期下降。肖温温等通过测定正常孕妇早、中、晚孕期空腹血糖水平,发现结果均低于正常非孕妇女[3]。通过高血糖与妊娠不良结局(the hyperglycemia and adverse pregnancy outcome study,HAPO)的流行病学研究[4,5],美国糖尿病协会(American Diabetes Association,ADA)与国际妊娠合并糖尿病研究组织(International Association of diabetes and pregnancy study groups,IADPSG)推荐GDM 诊断新标准,见本期相关内容[6]。孕期将孕前糖尿病以及 GDM 孕妇血糖控制在妊娠期正常水平至关重要,在临床工作中主要有以下几种监测孕妇血糖水平的方法。