Data stream management system (DSMS) provides convenient solutions to the problem of processing continuous queries on data streams.Previous approaches for scheduling these queries and their operators assume that each ...Data stream management system (DSMS) provides convenient solutions to the problem of processing continuous queries on data streams.Previous approaches for scheduling these queries and their operators assume that each operator runs in separate thread or all operators combine in one query plan and run in a single thread.Both approaches suffer from severe drawbacks concerning the thread overhead and the stalls due to expensive operators.To overcome these drawbacks,a novel approach called clustered operators scheduling (COS) is proposed that adaptively clusters operators of the query plan into a number of groups based on their selectivity and computing cost using S-mean clustering.Experimental evaluation is provided to demonstrate the potential benefits of COS scheduling over the other scheduling strategies.COS can provide adaptive,flexible,reliable,scalable and robust design for continuous query processor.展开更多
TSdb (http://tsdb.cbi.pku.edu.cn) is the first manually curated central repository that stores formatted information on the substrates of transporters. In total, 37608 transporters with 15075 substrates from 884 organ...TSdb (http://tsdb.cbi.pku.edu.cn) is the first manually curated central repository that stores formatted information on the substrates of transporters. In total, 37608 transporters with 15075 substrates from 884 organisms were curated from UniProt functional annotation. A unique feature of TSdb is that all the substrates are mapped to identifiers from the KEGG Ligand com- pound database. Thus, TSdb links current metabolic pathway schema with compound transporter systems via the shared compounds in the pathways. Furthermore, all the transporter substrates in TSdb are classified according to their biochemical properties, biological roles and subcellular localizations. In addition to the functional annotation of transporters, extensive compound annotation that includes inhibitor information from the KEGG Ligand and BRENDA databases has been integrated, making TSdb a useful source for the discovery of potential inhibitory mechanisms linking transporter substrates and metabolic enzymes. User-friendly web interfaces are designed for easy access, query and download of the data. Text and BLAST searches against all transporters in the database are provided. We will regularly update the substrate data with evidence from new publications.展开更多
By using the dimension-free Harnack inequality, the coupling method, and Bakry-Emery＇s argument, some explicit lower bounds are presented for the constant of the Beckner type inequality on compact manifolds. As appli...By using the dimension-free Harnack inequality, the coupling method, and Bakry-Emery＇s argument, some explicit lower bounds are presented for the constant of the Beckner type inequality on compact manifolds. As applications, the Beckner inequality and the transportation cost inequality are established for a class of continuous spin systems. In particular, some results in [1, 2] are generalized.展开更多
基金Project(50275150) supported by the National Natural Science Foundation of ChinaProject(20040533035) supported by the National Research Foundation for the Doctoral Program of Higher Education of China
文摘Data stream management system (DSMS) provides convenient solutions to the problem of processing continuous queries on data streams.Previous approaches for scheduling these queries and their operators assume that each operator runs in separate thread or all operators combine in one query plan and run in a single thread.Both approaches suffer from severe drawbacks concerning the thread overhead and the stalls due to expensive operators.To overcome these drawbacks,a novel approach called clustered operators scheduling (COS) is proposed that adaptively clusters operators of the query plan into a number of groups based on their selectivity and computing cost using S-mean clustering.Experimental evaluation is provided to demonstrate the potential benefits of COS scheduling over the other scheduling strategies.COS can provide adaptive,flexible,reliable,scalable and robust design for continuous query processor.
基金supported by the National High Technology Research and Development Program of China (Grant Nos. 2006AA02Z334, 2006AA02Z314, 2006AA02A312 and 2007AA02Z165)the National Basic Research Program of China (Grant Nos. 2006CB910404 and 2007CB946904)support of the K. C. Wong Education Foundation, Hong Kong
文摘TSdb (http://tsdb.cbi.pku.edu.cn) is the first manually curated central repository that stores formatted information on the substrates of transporters. In total, 37608 transporters with 15075 substrates from 884 organisms were curated from UniProt functional annotation. A unique feature of TSdb is that all the substrates are mapped to identifiers from the KEGG Ligand com- pound database. Thus, TSdb links current metabolic pathway schema with compound transporter systems via the shared compounds in the pathways. Furthermore, all the transporter substrates in TSdb are classified according to their biochemical properties, biological roles and subcellular localizations. In addition to the functional annotation of transporters, extensive compound annotation that includes inhibitor information from the KEGG Ligand and BRENDA databases has been integrated, making TSdb a useful source for the discovery of potential inhibitory mechanisms linking transporter substrates and metabolic enzymes. User-friendly web interfaces are designed for easy access, query and download of the data. Text and BLAST searches against all transporters in the database are provided. We will regularly update the substrate data with evidence from new publications.
基金Project supported by the National Natural Scienoe Fbundation of China (No.10121101)the Research Fund for the Doctoral Program of Higher Education (No.20040027009).
文摘By using the dimension-free Harnack inequality, the coupling method, and Bakry-Emery＇s argument, some explicit lower bounds are presented for the constant of the Beckner type inequality on compact manifolds. As applications, the Beckner inequality and the transportation cost inequality are established for a class of continuous spin systems. In particular, some results in [1, 2] are generalized.
