The two-parameter Weibull model is used to describe the fiber strength distribution.The stress carried by the intact and fracture fibers on the matrix crack plane during unloading/reloading is determined based on the ...The two-parameter Weibull model is used to describe the fiber strength distribution.The stress carried by the intact and fracture fibers on the matrix crack plane during unloading/reloading is determined based on the global load sharing criterion.The axial stress distribution of intact fibers upon unloading and reloading is determined based on the mechanisms of fiber sliding relative to matrix in the interface debonded region.The interface debonded length,unloading interface counter slip length,and reloading interface new slip length are obtained by the fracture mechanics approach.The hysteresis loops corresponding to different stresses considering fiber failure are compared with the cases without considering fiber failure.The effects of fiber characteristic strength and fiber Weibull modulus on the fiber failure,the shape,and the area of the hysteresis loops are analyzed.The predicted quasi-static unloading/reloading hysteresis loops agree well with experimental data.展开更多
The CBM (chromoblastomycosis) is a disease caused by dematiaceous fungi, which has the species Fonsecaea pedrosoi as main agent. This fungus is found in warm and moist climates, characteristically found in the amazo...The CBM (chromoblastomycosis) is a disease caused by dematiaceous fungi, which has the species Fonsecaea pedrosoi as main agent. This fungus is found in warm and moist climates, characteristically found in the amazonic lands of the region, where its environmental isolation was once described. This research aimed to identify the healthy population exposed to agent F. pedrosoi in four villages located in the Legal Amazon. In order to clarify the risk factors for allergic immune exposure, a survey was conducted by the technique of delayed skin reaction (IDR) with the metabolic antigen (chromomycin) in 449 healthy individuals. The results showed that 14.9% (67 subjects) were IDR positive, with induration 〉 5 mm. Multivariate analysis with logistic regression for risk factors: living in the village of Z6 Pedro (municipality of Bacabeira in the state of Maranhao, Brazil),展开更多
Underwater acoustic scattering echoes have time–space structures and are aliasing in time and frequency domains. Different series of echoes properties are not identified when incident angle is unknown. This article i...Underwater acoustic scattering echoes have time–space structures and are aliasing in time and frequency domains. Different series of echoes properties are not identified when incident angle is unknown. This article investigates variations in target echoes of monostatic sonar to address this problem. The mother wavelet with similar structures has been proposed on the basis of preprocessing signal waveform using matched filter, and the theoretical expressions between delay factor and incident angle are derived in the wavelet domain. Analysis of simulation data and experimental results in free-field pool show that this method can effectively separate geometrical scattering components of target echoes. The time delay estimation obtained from geometrical echoes at a single angle is consistent with target geometrical features, which provides a basis for object recognition without angle information. The findings provide valuable insights for analyzing elastic scattering echoes in actual ocean environment.展开更多
The control effect of recycled noise,generated by the superposition of a primary Gaussian noise source and a secondary source with a constant delay,has been studied in an excitable FitzHugh-Nagumo system.We mainly foc...The control effect of recycled noise,generated by the superposition of a primary Gaussian noise source and a secondary source with a constant delay,has been studied in an excitable FitzHugh-Nagumo system.We mainly focus on the performance of noise-induced spike and coherence resonance in a parameter region sub-threshold to supercritical Hopf bifurcation.For fixed noise intensity,simulations show that the coherence(quantitatively measured by R,which is defined as the mean value of the spike interval time T normalized to its mean square root) and the emission velocity of the noise-induced spikes exhibit damped oscillations with the variation of delay time,demonstrating a new kind of multi-resonance phenomenon.Furthermore,the optimal delay times for resonance and the fast emission velocity are related to the inherent frequency of the system.It seems that there are some synchronization effects between the dynamic character of the system and the delay time of recycled noise.Our results give clear information about how one can control the coherence and emission velocity of the noise-induced spike in a rather effective way,by deliberately adjusting the delay time and the fraction of the secondary noise.展开更多
Modeling genetic regulatory networks is an important research topic in genomic research and computationM systems biology. This paper considers the problem of constructing a genetic regula- tory network (GRN) using t...Modeling genetic regulatory networks is an important research topic in genomic research and computationM systems biology. This paper considers the problem of constructing a genetic regula- tory network (GRN) using the discrete dynamic system (DDS) model approach. Although considerable research has been devoted to building GRNs, many of the works did not consider the time-delay effect. Here, the authors propose a time-delay DDS model composed of linear difference equations to represent temporal interactions among significantly expressed genes. The authors also introduce interpolation scheme and re-sampling method for equalizing the non-uniformity of sampling time points. Statistical significance plays an active role in obtaining the optimal interaction matrix of GRNs. The constructed genetic network using linear multiple regression matches with the original data very well. Simulation results are given to demonstrate the effectiveness of the proposed method and model.展开更多
基金Supported by the National Natural Science Foundation of China(51075204)the Graduate Innovation Foundation of Jiangsu Province(CX08B-133Z)the Doctoral Innovation Foundation of Nanjing University of Aeronautics and Astronautics(BCXJ08-05)~~
文摘The two-parameter Weibull model is used to describe the fiber strength distribution.The stress carried by the intact and fracture fibers on the matrix crack plane during unloading/reloading is determined based on the global load sharing criterion.The axial stress distribution of intact fibers upon unloading and reloading is determined based on the mechanisms of fiber sliding relative to matrix in the interface debonded region.The interface debonded length,unloading interface counter slip length,and reloading interface new slip length are obtained by the fracture mechanics approach.The hysteresis loops corresponding to different stresses considering fiber failure are compared with the cases without considering fiber failure.The effects of fiber characteristic strength and fiber Weibull modulus on the fiber failure,the shape,and the area of the hysteresis loops are analyzed.The predicted quasi-static unloading/reloading hysteresis loops agree well with experimental data.
文摘The CBM (chromoblastomycosis) is a disease caused by dematiaceous fungi, which has the species Fonsecaea pedrosoi as main agent. This fungus is found in warm and moist climates, characteristically found in the amazonic lands of the region, where its environmental isolation was once described. This research aimed to identify the healthy population exposed to agent F. pedrosoi in four villages located in the Legal Amazon. In order to clarify the risk factors for allergic immune exposure, a survey was conducted by the technique of delayed skin reaction (IDR) with the metabolic antigen (chromomycin) in 449 healthy individuals. The results showed that 14.9% (67 subjects) were IDR positive, with induration 〉 5 mm. Multivariate analysis with logistic regression for risk factors: living in the village of Z6 Pedro (municipality of Bacabeira in the state of Maranhao, Brazil),
基金Foundation item: Supported by the National Natural Science Foundation of China(Grant No.51279033) and Natural Science Foundation of Heilongjiang Province, China(Grant No.F201346 )
文摘Underwater acoustic scattering echoes have time–space structures and are aliasing in time and frequency domains. Different series of echoes properties are not identified when incident angle is unknown. This article investigates variations in target echoes of monostatic sonar to address this problem. The mother wavelet with similar structures has been proposed on the basis of preprocessing signal waveform using matched filter, and the theoretical expressions between delay factor and incident angle are derived in the wavelet domain. Analysis of simulation data and experimental results in free-field pool show that this method can effectively separate geometrical scattering components of target echoes. The time delay estimation obtained from geometrical echoes at a single angle is consistent with target geometrical features, which provides a basis for object recognition without angle information. The findings provide valuable insights for analyzing elastic scattering echoes in actual ocean environment.
基金supported by the National Natural Science Foundation of China (21073232)the Fundamental Research Funds for the Central Universities (2010QNA16)the Research Fund of China University of Mining and Technology
文摘The control effect of recycled noise,generated by the superposition of a primary Gaussian noise source and a secondary source with a constant delay,has been studied in an excitable FitzHugh-Nagumo system.We mainly focus on the performance of noise-induced spike and coherence resonance in a parameter region sub-threshold to supercritical Hopf bifurcation.For fixed noise intensity,simulations show that the coherence(quantitatively measured by R,which is defined as the mean value of the spike interval time T normalized to its mean square root) and the emission velocity of the noise-induced spikes exhibit damped oscillations with the variation of delay time,demonstrating a new kind of multi-resonance phenomenon.Furthermore,the optimal delay times for resonance and the fast emission velocity are related to the inherent frequency of the system.It seems that there are some synchronization effects between the dynamic character of the system and the delay time of recycled noise.Our results give clear information about how one can control the coherence and emission velocity of the noise-induced spike in a rather effective way,by deliberately adjusting the delay time and the fraction of the secondary noise.
基金supported in part by HKRGC GrantHKU Strategic Theme Grant on Computational SciencesNational Natural Science Foundation of China under Grant Nos.10971075 and 11271144
文摘Modeling genetic regulatory networks is an important research topic in genomic research and computationM systems biology. This paper considers the problem of constructing a genetic regula- tory network (GRN) using the discrete dynamic system (DDS) model approach. Although considerable research has been devoted to building GRNs, many of the works did not consider the time-delay effect. Here, the authors propose a time-delay DDS model composed of linear difference equations to represent temporal interactions among significantly expressed genes. The authors also introduce interpolation scheme and re-sampling method for equalizing the non-uniformity of sampling time points. Statistical significance plays an active role in obtaining the optimal interaction matrix of GRNs. The constructed genetic network using linear multiple regression matches with the original data very well. Simulation results are given to demonstrate the effectiveness of the proposed method and model.