Objective To explore the effective therapy for deficiency syndrome in the maintenance hemodialysis patients of end-stage renal disease. Methods Ninety-seven maintenance hemodialysis patients of end-stage renal disease...Objective To explore the effective therapy for deficiency syndrome in the maintenance hemodialysis patients of end-stage renal disease. Methods Ninety-seven maintenance hemodialysis patients of end-stage renal disease were divided into an observation group （51 cases） and a control group （46 cases） randomly, and routine western medicines were used in both groups. On this base, moxibustion was given at Zusanli （足三里 ST 36） and Sanyijiao （三阴交 SP 6） with a paper-tube-moxibustion equipment in the observation group. The therapeutic effects on syndromes were evaluated by comparing the symptom scores in two groups before and after treatment. Results After treatment, all the symptom scores in the observation group were improved significantly （all P〈0.05）, with fatigue and weakness, short breath and aversion to talking, poor appetite, lassitude in loin and knees, aversion to cold, cool extremities and so on most obviously improved, and the total effective rate on the syndrome in observation group （64.7%, 33/51） was significantly higher than that in control group （23.9%, 11/46）, with a significant difference between the two groups （P〈0.05）. Conclusion Moxibustion can improve the clinical symptoms of maintenance hemodialysis patients of end-stage renal disease, and it has some therapeutic effect on the deficiency syndrome.展开更多
Objective To observe the effect of acupuncture at Quchi(LI11)on the serum interleukin-2(IL-2)level and the severity of uremic pruritus(UP)in hemodialysis patients.Methods Sixty hemodialysis patients with UP were rando...Objective To observe the effect of acupuncture at Quchi(LI11)on the serum interleukin-2(IL-2)level and the severity of uremic pruritus(UP)in hemodialysis patients.Methods Sixty hemodialysis patients with UP were randomized into an acupuncture group and a control group,with 30 cases in each group.In the acupuncture group,patients were treated with acupuncture at Quchi(LI11)twice a week for six weeks.In the control group,each patient received a placebo treatment(sham acupuncture).Before and after the intervention,the pruritis severity was examined using a 5-D scale,and the serum IL-2 level was measured using an enzyme-linked immunosorbent assay kit.Results There were no statistically significant differences in the demographic or clinical factors between the control group and the acupuncture group at baseline.The reduction in pruritus severity in patients was more significant in the acupuncture group(P=0.027).Acupuncture therapy also significantly decreased the serum IL-2 level in the patients(P=0.011).Throughout the acupuncture procedures,the incidence of pain and mild bleeding was 3.6%and 2.5%,respectively.Conclusion Six-week acupuncture treatment at Quchi(LI11)can effectively decrease the severity of UP and the serum IL-2 level.Large-scale,long-duration,and multi-center studies are needed to fully understand the role of IL-2 in inflammation and neuroimmune stimulation during acupuncture.展开更多
基金Supported by the second lot TCM superior diseases clinical research items of China Academy of Chinese Medical Sciences: CACMS07Y0019
文摘Objective To explore the effective therapy for deficiency syndrome in the maintenance hemodialysis patients of end-stage renal disease. Methods Ninety-seven maintenance hemodialysis patients of end-stage renal disease were divided into an observation group （51 cases） and a control group （46 cases） randomly, and routine western medicines were used in both groups. On this base, moxibustion was given at Zusanli （足三里 ST 36） and Sanyijiao （三阴交 SP 6） with a paper-tube-moxibustion equipment in the observation group. The therapeutic effects on syndromes were evaluated by comparing the symptom scores in two groups before and after treatment. Results After treatment, all the symptom scores in the observation group were improved significantly （all P〈0.05）, with fatigue and weakness, short breath and aversion to talking, poor appetite, lassitude in loin and knees, aversion to cold, cool extremities and so on most obviously improved, and the total effective rate on the syndrome in observation group （64.7%, 33/51） was significantly higher than that in control group （23.9%, 11/46）, with a significant difference between the two groups （P〈0.05）. Conclusion Moxibustion can improve the clinical symptoms of maintenance hemodialysis patients of end-stage renal disease, and it has some therapeutic effect on the deficiency syndrome.
文摘Objective To observe the effect of acupuncture at Quchi(LI11)on the serum interleukin-2(IL-2)level and the severity of uremic pruritus(UP)in hemodialysis patients.Methods Sixty hemodialysis patients with UP were randomized into an acupuncture group and a control group,with 30 cases in each group.In the acupuncture group,patients were treated with acupuncture at Quchi(LI11)twice a week for six weeks.In the control group,each patient received a placebo treatment(sham acupuncture).Before and after the intervention,the pruritis severity was examined using a 5-D scale,and the serum IL-2 level was measured using an enzyme-linked immunosorbent assay kit.Results There were no statistically significant differences in the demographic or clinical factors between the control group and the acupuncture group at baseline.The reduction in pruritus severity in patients was more significant in the acupuncture group(P=0.027).Acupuncture therapy also significantly decreased the serum IL-2 level in the patients(P=0.011).Throughout the acupuncture procedures,the incidence of pain and mild bleeding was 3.6%and 2.5%,respectively.Conclusion Six-week acupuncture treatment at Quchi(LI11)can effectively decrease the severity of UP and the serum IL-2 level.Large-scale,long-duration,and multi-center studies are needed to fully understand the role of IL-2 in inflammation and neuroimmune stimulation during acupuncture.
