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基于通博文化的初中生行动学习实践探索
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作者 王克强 《课堂内外(教师版)(中等教育)》 2020年第11期11-12,共2页
通博是清代学者李兆洛在推进书院教育时所提出的理念,在以通博文化为主导的书院教育中,教师先明确一个方向,然后激励学生自主学习,广泛阅读相关资料,进而抛出问题引发讨论,学生在争鸣中习得知识,形成新见解。基于通博文化的初中生行动... 通博是清代学者李兆洛在推进书院教育时所提出的理念,在以通博文化为主导的书院教育中,教师先明确一个方向,然后激励学生自主学习,广泛阅读相关资料,进而抛出问题引发讨论,学生在争鸣中习得知识,形成新见解。基于通博文化的初中生行动学习实践,主要围绕通博课程展开。建构通博课程框架,关键在于传承优秀传统文化,然后与时俱进,精准定位,结合教育教学规律形成可操作的内容。 展开更多
关键词 通博 传统文化 初中生 行动学习 课程
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通博益脑片人体药动学及生物等效性研究
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作者 刘建存 肖志勇 《长沙医学院学报》 2008年第2期32-36,共5页
目的:研究德康产通博益脑片与通博益脑胶囊在正常人体的药动学与生物等效性。方法: 18名健康男性志愿受试者随机交叉口服40mg受试制剂通博益脑片和参比制剂通博益脑胶囊40mg后,采用高效液相色谱法,以卡马西平为内标,测定两种制剂的血浆... 目的:研究德康产通博益脑片与通博益脑胶囊在正常人体的药动学与生物等效性。方法: 18名健康男性志愿受试者随机交叉口服40mg受试制剂通博益脑片和参比制剂通博益脑胶囊40mg后,采用高效液相色谱法,以卡马西平为内标,测定两种制剂的血浆药物浓度。结果:受试制剂和参比制剂均符合一级吸收开放性一室模型,主要药物代谢动力学参数0-12h药-时曲线下面积(AUC_(012))分别为(2719.9±1551.7)和(2820.8±1668.1)ngh/mL;锋浓度(C_(max))分别为(820.1±420.1)和(760.0±415.4)ng/mL;达峰时间(T_(max))分别为(2.4±0.6)和(2.5±0.6)h;血浆半衰期(T_(1/2))分别为(2.2±0.8)和(2.4±0.9)h。相对生物利用度为(99.69±13.51)%。结论:通博益脑片与通博益脑胶囊为生物等效制剂。 展开更多
关键词 通博益脑片 通博益脑胶囊 药动学 生物等效性
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通博益脑胶囊治疗高血压的疗效分析
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作者 刘建存 蒋先莲 +3 位作者 叶冠男 李云贵 王响群 肖志勇 《长沙医学院学报》 2005年第2期37-39,52,共4页
目的:评价通博益脑胶囊(CTB)治疗高血压病的临床疗效。方法:选择高血压病患者200例,随机分为4组,分别服用CTB(0.6~1.5g,3/d),硝苯地平控释片(5mg~10mg,2/d)、卡托普利(12.5mg,25mg,3/d)及阿替洛尔(6.25mg~25mg,3/d),连续30d,每5d1次... 目的:评价通博益脑胶囊(CTB)治疗高血压病的临床疗效。方法:选择高血压病患者200例,随机分为4组,分别服用CTB(0.6~1.5g,3/d),硝苯地平控释片(5mg~10mg,2/d)、卡托普利(12.5mg,25mg,3/d)及阿替洛尔(6.25mg~25mg,3/d),连续30d,每5d1次观察临床疗效、降压幅度和心率变化。结果:CTB组降压有效率为86.0%,略低于硝苯地平控释片组(90.0%)和卡托普利组(88.0%),高于阿替洛尔组(72.0%)。CTB组降压达到正常范围的时间迟于硝苯地平控释片和卡托普利组,早于阿替洛尔组,但无明显副作用。结论:通博益脑胶囊治疗高血压疗效确切,较硝苯地平控释片、卡托普利及阿替洛尔适用范围广。 展开更多
关键词 通博益脑胶囊 高血压病 疗效
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通博:抓住时机 超前做强
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作者 周文宝 《家庭影院技术》 2006年第5期51-51,共1页
通博近年的业绩在音响市场以20%-30%的年增长率迅速发展。这是由于我们投入大资金调查市场、分析市场。以求定位市场、决策市场、把握市场。1999年开始当音响市场逐渐走向低迷。不少名牌按捺不住浮躁之心。争相生产低廉产品打击市场... 通博近年的业绩在音响市场以20%-30%的年增长率迅速发展。这是由于我们投入大资金调查市场、分析市场。以求定位市场、决策市场、把握市场。1999年开始当音响市场逐渐走向低迷。不少名牌按捺不住浮躁之心。争相生产低廉产品打击市场、扩大代理争夺市场份额时,我们反道而行之:收缩代理,放弃低端(市场)。整饬制度。规范操作。当年一下缩减1/3的代理。事实证明这样的决策很有远见,经销商纷纷投入合作。商店门面统一高档设计装潢。 展开更多
关键词 音响市场 年增长率 市场份额 规范操作 代理 经销商 决策 业绩 资金 名牌 通博
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Effect of captopril or verapamil on intracellular sodium in cultured vascular smooth muscle cells
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作者 QI JIAN HUA LU ZHANG +3 位作者 JUN WANG MIN LU XIN MING WANG ZHENG JUN JIN(Shanghai Institute of Cell Biology, Chinese Academy of Sciences, Shanghai 200031, China.)(Department of Pharmacology, Shanghai Second Medical University, Shanghai 200025, China.) 《Cell Research》 SCIE CAS CSCD 1996年第1期47-53,共7页
The effects of captopril (Cap) and verapamil (Ver)alone and in combination on intracellular Na+ concentration ([Na+]i) in cultured aortic smooth muscle cells (ASMC) of rabbits was evaluated by a direct measurement of ... The effects of captopril (Cap) and verapamil (Ver)alone and in combination on intracellular Na+ concentration ([Na+]i) in cultured aortic smooth muscle cells (ASMC) of rabbits was evaluated by a direct measurement of [Na+]i with fluorescent dye sodium-binding benzofuran isophthalate (SBFI) combined with digital image. [Na+]i in resting cells was found to be 11.9 ± 0. 7 mmol/L. Angiotensin II (Ang-II, 0.1-10μmol/L) induced an increase of [Na+]i in concentration-dependent manner. Ver (0.1-10μmol/L) inhibited Ang-II (1 μmol/L)-induced increase in [Na+]i, while Cap enhanced Ang-II-induced increase in [Na+]i at 10μmol/L but not at 0.1-1μmol/L. Ver (0.1-1μmol/L)abolished enhancement of Ang-II-induced increase in [Na+]i by Cap. Thus, the inhibition of Capenhanced [Na+]i by Ver may provide a new hypothesis for the underlying molecular mechanism of synergistic effect of the combination of Ca2+ antagonists and angiotensinconverting enzyme inhibitors in controlling blood pressure. 展开更多
关键词 Cultured aortic smooth muscle cells angiotensin CAPTOPRIL VERAPAMIL sodiumbinding benzofuran isophthalate
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From Transcendence to "Altercendence"?
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作者 Pierre Leichner 《Journal of Literature and Art Studies》 2012年第7期730-739,共10页
There seems to be a renewed interest in the last couple decades in studying and writing about consciousness. Consciousness may be the most difficult question humans are trying to resolve. Yet eliciting transcendence, ... There seems to be a renewed interest in the last couple decades in studying and writing about consciousness. Consciousness may be the most difficult question humans are trying to resolve. Yet eliciting transcendence, a phenomenon that rises above, or goes beyond, normal limits of consciousness, has been an identified goal for many artists in the past, possibly even in cave art. Drawing on works shown in the 2006 Art Gallery of Hamilton exposition called Sublime Embrace: Experiencing Consciousness in Contemporary Art and in the 2002 Houston Contemporary Art Museum 2002 show called THE INWARD EYE: Transcendence in Contemporary Art, the author will explore the biological, psychological, cultural, and spiritual facets of transcendence. Perhaps, with the renewed symbiotic relationship between the sciences and art, the convergence of digital media, and the emergence of global communication networks, we are at the verge of art that will create a change, an alteration in our consciousness, and an altercendent state. What this change will be is yet a mystery. 展开更多
关键词 CONSCIOUSNESS TRANSCENDENCE bioart
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Hidden Crises and Communication: An Interactional Analysis of Hidden Crises
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作者 Annette Klarenbeek 《Journalism and Mass Communication》 2011年第3期168-184,共17页
In this paper I describe the ways in which the communication discipline can make a hidden crisis transparent. For this purpose I examine the concept of crisis entrepreneurship from a communication point of view. Using... In this paper I describe the ways in which the communication discipline can make a hidden crisis transparent. For this purpose I examine the concept of crisis entrepreneurship from a communication point of view. Using discourse analysis, I analyse the discursive practices of crisis entrepreneurs in the domain of education in the Netherlands. This paper is part of my Ph.D. project in which I examine the dilemmas encountered by crisis entrepreneurs and the interactional solutions they choose in addressing a crisis. In my Ph.D. project I have analysed how crisis entrepreneurs use discursive practices: (1) to show thefactuality of the problem. For example, the way the problem is presented is too theoretical and is not a problem in reality; (2) to present the credibility of the messenger as an authentic, legitimate spokesman. Crisis entrepreneurs may be accused of wanting to attract attention to their own cause; (3) to create the accountability for the problem and the solution. For example, crisis entrepreneurs can be accused of nursing personal grievances or of drawing attention to the issue without actively attempting to solve it. The conclusion is that a communication professional is able to recognize a problem raised by crisis entrepreneurs. Knowledge of interactional dilemmas helps communication professionals understand the potential of crisis entrepreneurs. A communication professional can therefore contribute to the recognition of crises by acknowledging that a crisis entrepreneur is someone who can have a strong hand in the public agenda, i.e., public affairs that are important to the authorities. 展开更多
关键词 hidden crisis crisis communication crisis entrepreneurs discourse analyses INTERACTION
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The Transmigrating Evil Genius: From Boothby to Rohmer to Fleming
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作者 Tom Mack 《Journal of Literature and Art Studies》 2012年第8期751-757,共7页
Literary characters possess a genealogy. Indeed, stock characters like the evil genius or super villain boast family trees that readers can trace not only through time--in this case, starting in the late 19th century-... Literary characters possess a genealogy. Indeed, stock characters like the evil genius or super villain boast family trees that readers can trace not only through time--in this case, starting in the late 19th century--but also across borders. This study traces the genealogical roots of the modern super villain by examining, in turn, Ian Fleming's characters Ernst Blofeld and Dr. Julius No, Sax Rohmer's Dr. Fu Manchu, and Guy Boothby's Dr. Antonio Nikola. In "Orientalism", the author contends that the modern super villain is the embodiment of these writers' orientalist fantasies and fears. Finally, in "Mad Science", the argument is made that the evil geniuses of Fleming, Rohmer, and Boothby may very well be the offspring of an earlier stock character, the mad scientist, who trades monomania for megalomania. 展开更多
关键词 Guy Boothby Sax Rohmer Ian Fleming stock character ORIENTALISM mad scientist
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