论通感性意象的语言呈现

钱钟书先生的《通感》一文,为我们开启了通感艺术的大门,此后,一些有心人试图探索通感艺术的奥秘。但,迄今为止,仍有许多学者认为通感是一种修辞格,他们想在修辞格中给通感一席之地。笔者认为,通感是一种心理现象,是审美主体在接受各种现象时,各个感官道(视觉、听觉、味觉等)在心理感受上产生的等价。这种心理活动不能同修辞格混为一谈,它只是修辞格的心理基础。借用一句时髦的话说:“通感”只能是某些修辞格的“深层结构”。

留白:英美意象派诗歌与茶道精神气质的相通之处

意象派诗歌以极端姿态表现了意象对于诗歌的重要作用,在英美现代诗歌舞台上虽短暂却意义非凡,开启诗歌内容自由的先河。在诸多鲜明的特点之中,对意境的追求和留白的隐藏是意象派诗歌最迷人的亮点。东方茶道文化对意境和留白的运用,都与意象派诗歌不谋而合。因此在意象派诗歌中寻找东方文化元素也就不足为奇。以不同的文化角度欣赏诗歌,从而见微知著,让读者以全新思维审视和欣赏意象派诗歌,从而更好地理解意象派诗歌的境界。

治疗性沟通对老年脑卒中病人自我感受负担的影响

[目的]探讨治疗性沟通对老年脑卒中病人自我感受负担(SPB)的影响。[方法]采用随机数字表法将60例存在SPB的老年脑卒中病人分夫妇为为两组各30例,对照组给予常规护理及一般性沟通,干预组在此基础上给予治疗性沟通,采用自我感受负担量表(SPBS)评价干预效果。[结果]干预后两组病人SPB总分、照护负担维度、情感负担维度得分以及SPB程度比较差异有统计学意义(P<0.01或P<0.05)。[结论]治疗性沟通能有效减轻老年脑卒中病人的自我感受负担。

从诗歌的开头透视象征主义的基本特征

作家们极为重视一部作品的开头,无论是小说家、散文家还是诗人无一例外,因为它将奠定作品的"总体语言和叙事方式还有风格,更重要的是展开叙事的角度与起点。"本文通过对象征主义诗歌开头部分的阐释,分析该派的象征性、通感性和音乐性等基本特征。

通信感知一体化的信息理论极限

无线感知已成为通信产业界广泛公认的、下一代无线网络中的原生能力.通信感知一体化将通信和感知功能集成在同一个无线系统中,能够提高资源利用率,减少基础设施开销,并增强通信和感知各自的性能.通信与感知间的性能折衷是通感一体化的关键基础理论问题之一.本文首先指出通感性能极限和可达性能边界是研究通感性能折衷的重要手段,然后从容量–失真理论、基于均方误差的通感性能边界理论、基于感知等效速率的通感性能边界理论,以及面向目标检测的通感性能边界理论4个方面出发,对相关的当前研究进展进行了详细总结与分析.文中指出通感性能折衷可进一步划分为确定–随机折衷和子空间折衷,并详细讨论了现有研究工作中与之相关的结论.在此基础上,讨论了基于实际的5G NR协议与帧结构的通感性能边界理论.最后,本文对通感一体化的信息理论极限中仍需关注和进一步研究的开放问题进行了总结.

Pinacidil reduces neuronal apoptosis following cerebral ischemia-reperfusion in rats through both mitochondrial and death-receptor signal pathways

Objective To investigate effect of pinacidil, an ATP sensitive potassium channel （KATP） opener, on the neuronal apoptosis and its signaling transduction mechanism following focal cerebral ischemia-reperfusion in rats. Methods One hundred male Wistar rats were randomly divided into four groups： A, sham-operated group; B, ischemia-reperfusion group; C, KATe opener treatment group; and D, KATe opener and blocker treatment group. The middle cerebral artery occlusion （MCAO） model was established by using the intraluminal suture occlusion method, neuronal apoptosis was determined by TUNEL staining, and expressions of caspase-8, caspase-9 and caspase-3 mRNA were detected by in situ hybridization. Results （1） The numbers of apoptotic neurons at 12 h, 24 h, 48 h, and 72 h were significantly less in group C than in groups B and D （P 〈 0.01 or P 〈 0.05）; and there was no difference between groups B and D at all time points （P 〉 0.05）. （2） The expressions of caspase-3 mRNA and caspase-8 mRNA at all times and the expressions of caspase-9 mRNA at 12 h, 24 h, 48 h, 72 h were significantly lower in group C than in groups B and D （P 〈 0.01 or P 〈 0.05）; and there were no differences between groups B and D at all time points （P 〉 0.05）. Conclusions KATP opener can significantly decrease the neuronal apoptosis and the expressions of caspase-3, caspase-8 and caspase-9 mRNAs following cerebral ischemiareperfusion. The neuronal apoptosis may be decreased by the inhibition of both mitochondrial and death-receptor signal pathways.

An optimized recording method to characterize biophysical and pharmacological properties of acid-sensing ion channel

Objective To re-confirm and characterize the biophysical and pharmacological properties of endogenously expressed human acid-sensing ion channel 1a （hASIC1a） current in HEK293 cells with a modified perfusion methods. Methods With cell floating method, which is separating the cultured cell from coverslip and putting the cell in front of perfusion tubing, whole cell patch clamp technique was used to record hASICla currents evoked by low pH external solution. Results Using cell floating method, the amplitude of hASICla currents activated by pH 5.0 in HEK293 cells is twice as large as that by the conventional method where the cells remain attached to coverslip. The time to reach peak at two different recording conditions is （21±5） ms and （270±25） ms, respectively. Inactivation time constants are （496±23） ms and （2284±120） ms, respectively. The cell floating method significantly increases the amiloride potency of block on hASIC 1 a [IC50 is （3.4± 1.1 ） μmol/L and （2.4± 0.9） μmol/L, respectively]. Both recording methods have similar pH activation ECs0 （6.6±0.6, 6.6±0.7, respectively）. Conclusion ASICs channel activation requires fast exchange of extracellular solution with the different pH values. With cell floating method, the presence of hASIC la current was re-confirmed and the biophysical and pharmacological properties of hASIC la channel in HEK293 cells was precisely characterized. This method could be used to study all ASICs and other ligand-gated channels that require fast extracellular solution exchange.

直觉型意象——诗的意象类型简论之一

本文论述直觉型意象是以诗人对客观存在的感知为基础,径直地写出诗人对事物的印象.它既为事物传神,也体现诗人的审美情趣。它又可分为直赋性意象.错觉性意象.通感性意象.

ATP-sensitive potassium channels:novel potential roles in Parkinson's disease

The ATP-sensitive potassium（KATP）channels which extensively distribute in diverse tissues（e.g.vascular smooth muscle,cardiac cells,and pancreas）are well-established for characteristics like vasodilatation,myocardial protection against ischemia,and insulin secretion.The aim of this review is to get insight into the novel roles of KATPchannels in Parkinson＇s disease（PD）,with consideration of the specificities KATPchannels in the central nervous system（CNS）, such as the control of neuronal excitability,action potential,mitochondrial function and neurotransmitter release.

Examples of Clinical Application of Fengchi

Fengchi (GB 20) is a point of the Gallbladder Channel of Foot-Shaoyang. Just as its name implies that it is a place where the pathogenic wind converges. So, the point is regarded as an important point to dispel wind since it has the functions of clearing heat and brightening the eye, dispelling wind and inducing resuscitation.

Effect of the ginsenoside Rb1 on the spontaneous contraction of intestinal smooth muscle in mice

AIM: To investigate the effect and the possible mechanism of ginsenoside Rb1 on small intestinal smooth muscle motility in mice. METHODS: Intestinal smooth muscle strips were isolated from male ICR mice (5 wk old), and the effect of ginsenoside Rb1 on spontaneous contraction was recorded with an electrophysiolograph. The effect of ginsenoside Rb1 on ion channel currents, including the voltage-gated K + channel current (IK V ), calcium-activated potassium channel currents (IK Ca ), spontaneous transient outward currents and ATP-sensitive potassium channel current (IK ATP ), was recorded on freshly isolated single cells using the whole-cell patch clamp technique. RESULTS: Ginsenoside Rb1 dose-dependently inhibited the spontaneous contraction of intestinal smooth muscle by 21.15% ± 3.31%, 42.03% ± 8.23% and 67.23% ± 5.63% at concentrations of 25 μmol/L, 50 μmol/L and 100 μmol/L, respectively (n=5,P<0.05). The inhibitory effect of ginsenoside Rb1 on spontaneous contraction was significantly but incompletely blocked by 10 mmol/L tetraethylammonium or 0.5 mmol/L 4-aminopyridine, respectively (n=5, P<0.05). However, the inhibitory effect of ginsenoside Rb1 on spontaneous contraction was not affected by 10 μmol/L glibenclamide or 0.4 μmol/L tetrodotoxin. At the cell level, ginsenoside Rb1 increased outward potassium currents, and IK V was enhanced from 1137.71 ± 171.62 pA to 1449.73 ± 162.39 pA by 50 μmol/L Rb1 at +60 mV (n=6, P<0.05). Ginsenoside Rb1 increased IK Ca and enhanced the amplitudes of spontaneous transient outward currents from 582.77 ± 179.09 mV to 788.12 ± 278.34 mV (n=5, P<0.05). However, ginsenoside Rb1 (50 μmol/L) had no significant effect on IK ATP (n=3, P<0.05). CONCLUSION: These results suggest that ginsenoside Rb1 has an inhibitory effect on the spontaneous contraction of mouse intestinal smooth muscle mediated by the activation of IK V and IK Ca , but the K ATP channel was not involved in this effect.

Cooperative Spectrum Sensing Exploiting a Certain Number of CR Users Based on Multi- Antennas in Cognitive Radio Networks

In this paper,a cooperative spectrum sensing scheme,which is based on cooperation of a certain number of secondary users and cooperative diversity under multi-antenna scenario,is proposed.Under multi-antenna scenario,we set a targeted detection probability and optimize the false alarm probability of the network by choosing a certain number of secondary users with the highest primary user’s signal to noise ratio.The detection performance of the network is also evaluated when all the secondary users are cooperating to illustrate the benefits of the proposed scheme as a contrast.In addition,how to choose the detection threshold of the secondary user is analyzed for the purpose of decreasing the average risk.Theory analysis and simulation results show that the optimum false alarm probability can be derived by cooperating a certain number of secondary users rather than all the secondary users and the detection performance of the network can be further improved if secondary users are equipped with multiple antennas.Also,a minimum average risk can be obtained by optimizing the detection threshold.

Role of JNK signaling pathway in sensitivity to radiotherapy of nasopharyngeal carcinoma

Objective:The aim of the study was to investigate the effect of c-Jun N-terminal protein kinase(JNK) signaling pathway on influencing the sensitivity to radiotherapy of human nasopharyngeal carcinoma CNE cells.Methods:Human nasopharyngeal carcinoma CNE multicellular spheroids(MCS) were constructed with three dimensional cell culture methods.Western blot was employed to analyze the activity of JNK signaling pathway in MCS after X-ray irradiation,and the expression of caspase-3 protein before and after using SP600125(a special inhibitor of JNK).X-ray induced cell apoptosis in MCS before and after treated with SP600125 were detected by TUNEL.Results:The level of JNK phosphorylation in MCS was a dynamic course after radiation,and there was a phosphorylation peaks at 2 h later,the apoptotic rate of MCS(P < 0.05) and the expression of caspase-3 protein(P < 0.05) were significantly increased after treated with SP600125.Conclusion:The transient activation of JNK played a important role in sensitivity to radiotherapy of CNE MCS via mediating survival signals,blocking this pathway accelerate cell apoptosis,which may be related to the increased expression of caspase-3.

Has the Drake Passage Played an Essential Role in the Cenozoic Cooling?

The Drake Passage is the seaway between South America and Antarctica. It is widely believed that the thermal isolation effects caused by the opening of the Drake Passage played an important role in the abrupt cooling that occurred at the Eocene-Oligocene boundary in the Cenozoic. These effects are also thought to be independent of the geometry of the passage. Here, the authors demonstrate that the climate impacts of the Drake Passage depend on the passage geometry by comparing the climate's sensitivity to the opening of the Drake Passage under the present and the Early Eocene land-sea configurations. These experiments show that the thermal isolation effects caused by the passage are much stronger under the present land-sea configuration. In comparison, under the Early Eocene land-sea configuration, the weak anomalies in heat transport caused by the opening of the narrow and shallow Drake Passage are not strong enough to thermally insulate Antarctica. The climate effects of the Drake Passage on the Cenozoic cooling have been overestimated in previous sensitivity studies carried out using the present land-sea configuration. Thus, it is unlikely that the opening of the Drake Passage played an essential role in the abrupt Cenozoic cooling, especially in the abrupt cooling at the Eocene-Oligocene boundary.

Network Coding-Aware Cooperative Relaying for Downlink Cellular Relay Networks

In this paper, we first overview some traditional relaying technologies, and then present a Network Coding-Aware Cooperative Relaying （NC2R） scheme to improve the performance of downlink transmission for relayaided cellular networks. Moreover, systematic performance analysis and extensive simulations are performed for the proposed NC2R and traditional relaying and non-relaying schemes. The results show that NCR outperforms conventional relaying and non-relaying schemes in terms of blocking probability and spectral efficiency, especially for cell-edge users. Additionally, the location selections for relays with NCR are also discussed. These results will provide some insights for incorporating network coding into next-generation broadband cellular relay mobile systems.

Coordinated node scheduling for energy-conserving in large wireless sensor networks

Aiming at developing a node scheduling protocol for sensor networks with fewer active nodes,we propose a coordinated node scheduling protocol based on the presentation of a solution and its optimization to determine whether a node is redundant.The proposed protocol can reduce the number of working nodes by turning off as many redundant nodes as possible without degrading the coverage and connectivity.The simulation result shows that our protocol outperforms the peer with respect to the working node number and dynamic coverage percentage.

Model for the Vaccination against the Poliomyelitis

The poliomyelitis is an acute infection produced by the polio virus that affects the human central nervous system. It is transmitted by fecal-oral and respiratory contact.There are two types of vaccine, OPV （live attenuated virus） and IPV （inactivated polio virus）. Currently, there is a plan of vaccination until the age of 5 with OPV. The children vaccinated expel a virus （derived from the vaccine） to the environment, and some of the people that have oral contact with them, get vaccinated by the herd behavior. Nevertheless, taking into account the lately observed facts about the reversion to virulence of the oral polio vaccine during its circulation in the environment, a change in the current vaccination schedule is being contemplated, where the oral polio vaccine can be replaced by the inactivated vaccine. Nowadays, In Colombia the inactivated oral polio vaccine is recommended for children presenting immune deficiency who are vaccinated with IPV. These children do not expel poliovirus to the environment. This work presents a mathematical model that describes the dynamics of the infection in a population where the two types of vaccination are carried out. The population is divided into two groups of age and Michaelis-Menten interactions. Different strategies of vaccination are simulated and analyzed.

论《青年艺术家的肖像》的语言艺术

《青年艺术家的肖像》的语言极富活力和魔力,这主要源自它的对应性、通感性、音乐性、隐喻性和象征性。本文从文本入手,结合具体的语言实例,剖析了《肖像》语言的五大特征。

Myocardial protection with pinacidil induced hyperpolarized arrest during cardiopulmonary bypass

Objective To investigate the myocardial protective effects of pinacidil induced hyperpolarized arrest and compare with those afforded by conventional depolarized hyperkalemic arrestMethods Eighteen dogs were equally divided into three groups: normothermic hyperpolarized group (Group A), hypothermic hyperpolarized group (Group B), and hyperkalemic group (Group C) Pinacidil (50μmol/L) containing 37℃ St Thomas solution (K+5mmol/L, 10ml/kg), pinacidil (50μmol/L, Sigma, USA) containing 4℃ St Thomas solution (K+ 5mmol/L, 10ml/kg) and 4℃ standard St Thomas solution (K+ 16mmol/L, 10ml/kg) were infused respectively through the aortic root after aorticclamping Heart arrest and its recovery, ultrastructure of the myocardium, the level of serum myocardial enzymes, and lipid peroxide and adenine cleotide of the myocardium were measuredHemodynamics during ischemia and after reperfusion were observedResults The percentages of normal mitochondria and glycogen did not change much during ischemia (except at 60 min) and after reperfusion in B Group, but declined markedly in Group C 30 min and 60 min after ischemia and 20 min after reperfusion (P<0.01) In Group A,they were lower than those of Group B before ischemia, but higher than those of Group C The recoveries of CO, SV, CI, LVSW, RVSW and MAP in Group B were significantly better than those in other two groups 15 min and 30 min after reperfusion (P<0.05and0.01, respectively) However, they were still better in Group A than those in Group C(P<0.05 and 0.01, respectively)The onset of heart arrest was faster in Groups C and B than that in Group A Highly elevated serum myocardial enzymes were observed 60 min after ischemia and 20 min after reperfusion in Group C, while they were only mild in the hyperpolarized groups, especially in Group B, and their recoveries were rapid Adenine nucleotides of the myocardium were better preserved in Group B than in other two groups 30 min, 60 min after ischemia, and 20 min after reperfusion (P<0.05 and 0.01, respectively)They were also much better in Group A than in GroupC(P<0.05and0.01,respectively)Lipid peroxide of the myocardium were significantly lower in Group B than in other groups 20 min after reperfusion (P<0.01),and they were lower in Group A than in Group C(P<0.05) Conclusions Myocardial protection for global ischemia during cardiopulmonary bypass (CPB) could be achieved with hyperpolarized heart arrest induced by pinacidil, an ATP sensitive potassium channel opener,especially in the hypothermic state The protection is weaker in normothermia but is still superior to that with traditional depolarized hyperkalemic arrest