Mesenchymal stromal cells(MSCs) are adult multipotent stem cells residing as pericytes in various tissues and organs where they can differentiate into specialized cells to replace dying cells and damaged tissues. Thes...Mesenchymal stromal cells(MSCs) are adult multipotent stem cells residing as pericytes in various tissues and organs where they can differentiate into specialized cells to replace dying cells and damaged tissues. These cells are commonly found at injury sites and in tumors that are known to behave like "wounds that do not heal." In this article, we discuss the mechanisms of MSCs in migrating, homing, and repairing injured tissues. We also review a number of reports showing that tumor microenvironment triggers plasticity mechanisms in MSCs to induce malignant neoplastic tissue formation, maintenance, and chemoresistance, as well as tumor growth. The antitumor properties and therapeutic potential of MSCs are also discussed.展开更多
Both of slow-moving traffic and motor traffic have an impact on waterfront development. Waterfront traffic has to based on analysis of local transport and land- scaping, road analysis vertically, horizontally and cros...Both of slow-moving traffic and motor traffic have an impact on waterfront development. Waterfront traffic has to based on analysis of local transport and land- scaping, road analysis vertically, horizontally and cross-section, as well as road space, structuring and the beauty of art. The target is to build waterfront traffic full of city characters.展开更多
文摘Mesenchymal stromal cells(MSCs) are adult multipotent stem cells residing as pericytes in various tissues and organs where they can differentiate into specialized cells to replace dying cells and damaged tissues. These cells are commonly found at injury sites and in tumors that are known to behave like "wounds that do not heal." In this article, we discuss the mechanisms of MSCs in migrating, homing, and repairing injured tissues. We also review a number of reports showing that tumor microenvironment triggers plasticity mechanisms in MSCs to induce malignant neoplastic tissue formation, maintenance, and chemoresistance, as well as tumor growth. The antitumor properties and therapeutic potential of MSCs are also discussed.
文摘Both of slow-moving traffic and motor traffic have an impact on waterfront development. Waterfront traffic has to based on analysis of local transport and land- scaping, road analysis vertically, horizontally and cross-section, as well as road space, structuring and the beauty of art. The target is to build waterfront traffic full of city characters.
