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驻极体促进水杨酸甲酯的体外透皮释药 被引量:16
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作者 崔黎丽 江键 +3 位作者 张利 宋诚荣 赵卫权 林锦明 《第二军医大学学报》 CAS CSCD 北大核心 2001年第5期415-417,共3页
目的 :研究负极性驻极体对水杨酸甲酯透皮扩散的影响。方法 :用改进的 Franz扩散池和高效液相色谱 (HPL C)法测定水杨酸甲酯通过离体小鼠皮肤的通透流量。结果 :与对照组相比 ,负极性驻极体组水杨酸甲酯的皮肤通透流量增加 1.5 5倍 ,且... 目的 :研究负极性驻极体对水杨酸甲酯透皮扩散的影响。方法 :用改进的 Franz扩散池和高效液相色谱 (HPL C)法测定水杨酸甲酯通过离体小鼠皮肤的通透流量。结果 :与对照组相比 ,负极性驻极体组水杨酸甲酯的皮肤通透流量增加 1.5 5倍 ,且有显著性差异 (P<0 .0 5 )。 结论 :负极性驻极体对水杨酸甲酯的透皮扩散有促进作用。 展开更多
关键词 驻极体 皮扩散 水杨酸甲酯 通透流量 体外皮释药
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Experimental and CFD Study on the Role of Fluid Flow Pattern on Membrane Permeate Flux 被引量:7
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作者 A. Parvareh M. Rahimi +1 位作者 S. S. Madaeni A. A. Alsairafi 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2011年第1期18-25,共8页
This paper reports a study on the role of fluid flow pattern and dynamic pressure on the permeate flux through a micro filtration membrane in laboratory scale.For this purpose,a dead-end membrane cell equipped with a ... This paper reports a study on the role of fluid flow pattern and dynamic pressure on the permeate flux through a micro filtration membrane in laboratory scale.For this purpose,a dead-end membrane cell equipped with a marine type impeller was used.The impeller was set to rotate in the clockwise and counter clockwise directions with the same angular velocities in order to illustrate the effect of rotation direction on permeate flux.Consequently, permeate fluxes were measured at various impeller rotational speeds.The computational fluid dynamics(CFD)predicted dynamic pressure was related to the fluxes obtained in the experiments.Using the CFD modeling,it is proven that the change in dynamic pressure upon the membrane surface has direct effect on the permeate flux. 展开更多
关键词 MEMBRANE MICROFILTRATION computational fluid dynamics modeling permeate flux
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Finite element simulation on percolation of low permeability reservoir with permeability anisotropy 被引量:2
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作者 ZHI Qingong ZHAO Yizhong +2 位作者 CHENG Yuanfang SUN Dexu DU Peng 《Global Geology》 2012年第4期265-269,共5页
In low permeability porous media which permeability anisotropy is ubiquitous,the percolation of fluid no longer follows linear Darcy’s Law.Oil-water two phase flow equation of low permeability reservoir with permeabi... In low permeability porous media which permeability anisotropy is ubiquitous,the percolation of fluid no longer follows linear Darcy’s Law.Oil-water two phase flow equation of low permeability reservoir with permeability anisotropy is established based on generalized Darcy’s law and starting pressure gradient,corresponding finite element program is developed and simulated based on the Finite Element Program Generator system (FEPG).The results show that energy-gathering exists in the flow event of flowing area front in low permeability reservoir.In the process of energy-gathering,the flow velocity changed little but increased rapidly as soon as the pressure gradient exceeded the starting pressure gradient of the reservoir,then gradually stabilized.The greater the starting pressure gradient is,the greater the near wellbore pressure drop is,the smaller the area influenced by the reservoir pressure changes caused by water injection and oil recovery.The greater the starting pressure gradient is,the lower the water saturation in same point of the reservoir is,the smaller the water flood swept area is.There will be more difficulties in water injection to the same extent. 展开更多
关键词 ANISOTROPY low permeability PERCOLATION finite element SIMULATION
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