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抗菌药物血脑屏障通透能力的研究进展 被引量:5
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作者 孔小清 张凤娥 《药品评价》 CAS 2019年第19期7-8,12,共3页
本研究对抗菌药物通过血脑屏障的能力及其影响因素进行分析总结,发现磺胺类、利奈唑胺、氧氟沙星、硝唑类、吡嗪酰胺、异烟肼以及部分喹诺酮类药物等抗菌药物脑膜炎时血脑屏障通透率较为理想,效果显著,安全性高。
关键词 抗菌药物 血脑屏障 通透能力
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Negative effect improvement of accelerated curing on chloride penetration resistance of ordinary concrete
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作者 李果 董雷 +1 位作者 王丹 颜成华 《Journal of Southeast University(English Edition)》 EI CAS 2017年第1期79-85,共7页
Four mineral admixture concrete specimens werefabricated to study the negative effect improvements ofaccelerated curing on the chloride penetration resistance ofordinary concrete. After reaching different initial stre... Four mineral admixture concrete specimens werefabricated to study the negative effect improvements ofaccelerated curing on the chloride penetration resistance ofordinary concrete. After reaching different initial strengths, the specimens were placed in 40, 60, or 80 t water tanks foraccelerated curing. The Coulomb values of the specimens weemeasured with ASTM C1202 experiment at 28, 100, 200, ad300 d. Partial specimens were also selected for rapid chlorideion migration coefficient and mercury intrusion porosimetryexperiments. The experimental results show that theaccelerated curing for ordinary concrete linealy deterioratesthe chloride penetration resistance, whereas the incorporationof mineral admixtures improves the concrete microscopic pore-structures and negative effects. An upper temperature limit of60 t of the accelerated curing is suitable for obtainingsuperior chloride penetration resistance for the mineraladmixture concrete. Pre-curing at a normal temperature of 20t is beneficial for improving the negative effect, which isalso aieviated with increasing testing age as a result of thesuccessive hydration of binder materials in concrete. 展开更多
关键词 negative effect improvement chloride penetration resistance ordinay concrete accelerated curing
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血必净联合胸腺肽治疗重症肺炎100例临床效果分析 被引量:4
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作者 谢国林 《临床医学》 CAS 2016年第3期47-48,共2页
目的分析血必净与胸腺肽联合治疗重症肺炎的效果。方法选取100例重症肺炎患者为研究对象,随机分组分为观察组与对照组,每组50例,观察组给予胸腺肽+血必净联合治疗,对照组给予单纯胸腺肽治疗。结果观察组患者治疗有效率为96.0%,明显高于... 目的分析血必净与胸腺肽联合治疗重症肺炎的效果。方法选取100例重症肺炎患者为研究对象,随机分组分为观察组与对照组,每组50例,观察组给予胸腺肽+血必净联合治疗,对照组给予单纯胸腺肽治疗。结果观察组患者治疗有效率为96.0%,明显高于对照组(86.0%,P<0.05);治疗后观察组患者白细胞计数和C-反应蛋白水平分别为(8.16±3.02)×109/L、(31.60±9.55)mg/L,对照组分别为(9.28±3.05)×109/L(37.79±10.87)mg/L,差异有统计学意义(P<0.05);治疗后观察组患者氧分压明显高于对照组,二氧化碳分压、心率低于对照组(P<0.05);治疗后观察组患者血管通透水平为(0.52±0.02)g/L,明显低于对照组的(0.58±0.01)g/L(P<0.05);观察组患者肺部顺应能力为(209.78±21.44)ml/cm H2O(1 cm H2O=0.098 k Pa),对照组为(201.57±20.58)ml/cm H2O,两组比较差异有统计学意义(P<0.05)。结论应用胸腺肽+血必净联合治疗重症肺炎效果明显,值得临床推广使用。 展开更多
关键词 血必净 胸腺肽 重症肺炎 炎性因子指标 血管通透能力
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