AIM:To clarify which method has accuracy:2nd gen-eration contrast-enhanced ultrasound or biopsy of portal vein thrombus in the differential diagnosis of portal vein thrombosis.METHODS:One hundred and eighty-six patien...AIM:To clarify which method has accuracy:2nd gen-eration contrast-enhanced ultrasound or biopsy of portal vein thrombus in the differential diagnosis of portal vein thrombosis.METHODS:One hundred and eighty-six patients with hepatocellular carcinoma and portal vein thrombosis underwent in blinded fashion a 2nd generation contrast-enhanced ultrasound and biopsy of portal vein thrombus;both results were examined on the basis of the follow-up of patients compared to reference-standard.RESULTS:One hundred and eight patients completed the study.Benign thrombosis on 2nd generation contrast-enhanced ultrasound was characterised by progressive hypoenhancing of the thrombus;in malignant portal vein thrombosis there was a precocious homo-geneous enhancement of the thrombus.On follow-up there were 50 of 108 patients with benign thrombosis:all were correctly diagnosed by both methods.There were 58 of 108 patients with malignant thrombosis:amongst these,52 were correctly diagnosed by both methods,the remainder did not present malignant cells on portal vein thrombus biopsy and showed on 2nd generation contrast-enhanced ultrasound an inho-mogeneous enhancement pattern.A new biopsy during the follow-up,guided to the area of thrombus that showed up on 2nd generation contrast-enhanced ultra-sound,demonstrated an enhancing pattern indicating malignant cells.CONCLUSION:In patients with hepatocellular carcinoma complicated by portal vein thrombosis,2nd generation contrast-enhanced ultrasound of portal vein thrombus is very useful in assessing the benign or malignant nature of the thrombus.Puncture biopsy of thrombus is usually accurate but presents some sampling errors,so,when pathological results are required,2nd generation contrast-enhanced ultrasound could guide the sampling needle to the correct area of the thrombus.展开更多
In the present study, the effect of electroacupuncture (EA) of acupoints of Ren, Spleen and Stomach Meridians on artificial abortion induced side effects was observed in 100 artificial abortion women. In comparison wi...In the present study, the effect of electroacupuncture (EA) of acupoints of Ren, Spleen and Stomach Meridians on artificial abortion induced side effects was observed in 100 artificial abortion women. In comparison with 45 artificial abortion women in the control group (who had not accepted EA treatment), EA possessed significant effects in relieving abdominal pain, reducing vaginal bleeding duration, lowering infection rate and infertility rate after artificial abortion operation.展开更多
Stress distribution of holed geotextile cross-section under uniaxial and double-axial tension is analyzed with the boundary element method (BEM). The calculation results indicate that stress distribution of holed geot...Stress distribution of holed geotextile cross-section under uniaxial and double-axial tension is analyzed with the boundary element method (BEM). The calculation results indicate that stress distribution of holed geotextile cross-section is greatly related to the dimension of the specimen, the size of the hole, the shape of the hole and the tensile condition, and the stress concentration area of holed geotextile from the side of the hole to 3-4 times of the hole diameter should be strengthened in order to improve quality of the projects. These results could provide guidance for engineering application of geotextiles.展开更多
Objective To investigate the direct effect of leptin on osteoblast-like cell line MG63. Methods Human osteoblast-like cell line MG63 was incubated with leptin of different doses for 24, 48 and 72 h, respectively. The ...Objective To investigate the direct effect of leptin on osteoblast-like cell line MG63. Methods Human osteoblast-like cell line MG63 was incubated with leptin of different doses for 24, 48 and 72 h, respectively. The proliferation of MG63 was determined by methylene blue assay. Alphal （1） collagen gene expression in MG63 was determined by real time flourescenee quantitive PCR （FQ-PCR）, both with 17β-E2 as positive control. Results Leptin accelerated the proliferation and differentiation of MG63 in dose and time-dependent manners, with the best effect at 10^-7 mol/L at 72 h. Compared with 17β-E2, leptin showed a weaker promoting effect at all of the three time point： 24, 48 and 72 h. While the effects of the two hormones have an approaching trend the time prolonged. Conclusion Leptin has the effects of accelerating the proliferation and differentiation of MG63 cells in vitro, which is more enduring and later than that of 17β-E2.展开更多
The polar motion excited by the fluctuation of global atmospheric angular momentum (AAM) is investigated. Based on the global AAM data, numerical results demonstrate that the fluctuation of AAM can excite the seasonal...The polar motion excited by the fluctuation of global atmospheric angular momentum (AAM) is investigated. Based on the global AAM data, numerical results demonstrate that the fluctuation of AAM can excite the seasonal wobbles (e.g., the 18-month wobble) and the Chandler wobble, which agree well with previous studies. In addition, by filtering the dominant low frequency components, some distinct polar wobbles corresponding to some great diurnal and semi-diurnal atmospheric tides are found.展开更多
文摘AIM:To clarify which method has accuracy:2nd gen-eration contrast-enhanced ultrasound or biopsy of portal vein thrombus in the differential diagnosis of portal vein thrombosis.METHODS:One hundred and eighty-six patients with hepatocellular carcinoma and portal vein thrombosis underwent in blinded fashion a 2nd generation contrast-enhanced ultrasound and biopsy of portal vein thrombus;both results were examined on the basis of the follow-up of patients compared to reference-standard.RESULTS:One hundred and eight patients completed the study.Benign thrombosis on 2nd generation contrast-enhanced ultrasound was characterised by progressive hypoenhancing of the thrombus;in malignant portal vein thrombosis there was a precocious homo-geneous enhancement of the thrombus.On follow-up there were 50 of 108 patients with benign thrombosis:all were correctly diagnosed by both methods.There were 58 of 108 patients with malignant thrombosis:amongst these,52 were correctly diagnosed by both methods,the remainder did not present malignant cells on portal vein thrombus biopsy and showed on 2nd generation contrast-enhanced ultrasound an inho-mogeneous enhancement pattern.A new biopsy during the follow-up,guided to the area of thrombus that showed up on 2nd generation contrast-enhanced ultra-sound,demonstrated an enhancing pattern indicating malignant cells.CONCLUSION:In patients with hepatocellular carcinoma complicated by portal vein thrombosis,2nd generation contrast-enhanced ultrasound of portal vein thrombus is very useful in assessing the benign or malignant nature of the thrombus.Puncture biopsy of thrombus is usually accurate but presents some sampling errors,so,when pathological results are required,2nd generation contrast-enhanced ultrasound could guide the sampling needle to the correct area of the thrombus.
文摘In the present study, the effect of electroacupuncture (EA) of acupoints of Ren, Spleen and Stomach Meridians on artificial abortion induced side effects was observed in 100 artificial abortion women. In comparison with 45 artificial abortion women in the control group (who had not accepted EA treatment), EA possessed significant effects in relieving abdominal pain, reducing vaginal bleeding duration, lowering infection rate and infertility rate after artificial abortion operation.
文摘Stress distribution of holed geotextile cross-section under uniaxial and double-axial tension is analyzed with the boundary element method (BEM). The calculation results indicate that stress distribution of holed geotextile cross-section is greatly related to the dimension of the specimen, the size of the hole, the shape of the hole and the tensile condition, and the stress concentration area of holed geotextile from the side of the hole to 3-4 times of the hole diameter should be strengthened in order to improve quality of the projects. These results could provide guidance for engineering application of geotextiles.
基金Supported by grants from Bureau of Health of Guangdong Province, China(A2002293).
文摘Objective To investigate the direct effect of leptin on osteoblast-like cell line MG63. Methods Human osteoblast-like cell line MG63 was incubated with leptin of different doses for 24, 48 and 72 h, respectively. The proliferation of MG63 was determined by methylene blue assay. Alphal （1） collagen gene expression in MG63 was determined by real time flourescenee quantitive PCR （FQ-PCR）, both with 17β-E2 as positive control. Results Leptin accelerated the proliferation and differentiation of MG63 in dose and time-dependent manners, with the best effect at 10^-7 mol/L at 72 h. Compared with 17β-E2, leptin showed a weaker promoting effect at all of the three time point： 24, 48 and 72 h. While the effects of the two hormones have an approaching trend the time prolonged. Conclusion Leptin has the effects of accelerating the proliferation and differentiation of MG63 cells in vitro, which is more enduring and later than that of 17β-E2.
基金Supported by the Special Project Fund of State Key Laboratory of Information Engineering in Surveying,Mapping and Remote Sensing(China)the Ph.D.Candidates Self-research(including1+4)Program of Wuhan Unversity in2008(No.49)+1 种基金the Engagement Fund of Outstanding Doctoral Dissertation of Wuhan University(No.22)the Open Fund of Key Laboratory of Geospace Environment and Geodesy,Ministry of Education,China(No.08-02-02)
文摘The polar motion excited by the fluctuation of global atmospheric angular momentum (AAM) is investigated. Based on the global AAM data, numerical results demonstrate that the fluctuation of AAM can excite the seasonal wobbles (e.g., the 18-month wobble) and the Chandler wobble, which agree well with previous studies. In addition, by filtering the dominant low frequency components, some distinct polar wobbles corresponding to some great diurnal and semi-diurnal atmospheric tides are found.
