针刺造影P-糖蛋白抑制胃肠肿瘤耐药作用分析

目的：研究针刺造影P-糖蛋白抑制抗胃肠肿瘤耐药作用,为胃肠肿瘤患者的康复治疗提供药物辅助治疗方案.方法：选择相关指标进行测试,采用小肠X射线气钡双重对比造影、纤维小肠镜、肠系膜上动脉造影等方法进行抑制抗胃肠肿瘤耐药作用评估.结果：以[P〈0.05]为差异均表示统计学上的显著性差异特征.观测指标包括胃肠分泌的6-乙酸苄酯己内酯、PEO链段上亚甲基氢,采用LOAD-max对比,与P〈0.05和P〈0.01.分析得出DP,PP,MAP的显著性差异P〈0.05,统计结果显示,在肿瘤半衰期代谢时间为20-30 h,得出患者的抗药变性检测形态变化曲线.结论：通过针刺造影P-糖蛋白抑制抗胃肠肿瘤耐药性作用分析,患者的胃肠肿瘤块缩小,可以有效提高患者的免疫能力,降低赖药性,提高抵抗力,促进患者康复.

针刺法低张静脉肾盂造影诊断肾癌50例分析

目的:探讨在针灸穴位刺激下,使泌尿系平滑肌松弛,达低张状态后,对肾癌的造影显示价值。方法:分析50例经手术与病理证实的肾癌患者应用针刺法低张造影的准备和操作方法以及检查结果。结果:50例患者中,显影优良率为58%,比654-2低张法显影优良率52%有所提高。结论:针刺法低张静脉肾盂造影诊断肾癌是一种有价值的泌尿系检查方法,它避免了临床上常用抗胆碱药物654-2的毒副作用,扩大了肾癌的检查范围,使过去不能进行造影的患者,做到早期发现与诊断,保证了其生存质量,因而,可作为临床对肾癌的常规检查方法加以推广。

经周围静脉Sono Vue超声造影诊断肾动脉狭窄价值的探讨

目的 探讨经周围静脉SonoVue超声造影对肾动脉狭窄诊断的作用。方法 对临床疑有肾动脉狭窄而超声基础显像不佳的 6例患者进行经静脉超声造影检查 ,与血管造影结果对比。结果 静脉注射SonoVue后 ,在全部病例中观察到肾动脉彩色血流信号增强 ,增强时间平均为 (72 0± 2 0 )s。造影后血流显像的评分提高。超声造影后导致3例患者的诊断和治疗方式改变 ,其余 3例造影结论未对患者的诊疗方法产生影响。结论 经周围静脉注入SonoVue超声造影剂后 ,多普勒信号增强时间可以满足临床工作的需要 ,选择造影的适应证可以提高造影剂应用价值 ,分析造影结果时需正确认识造影伪像。

针刺低张双对比造影对原发性胃肠道淋巴瘤的影像诊断作用分析

目的:探讨针刺低张双对比造影在原发性胃肠道淋巴瘤的影像学检查和诊断中的作用。方法:选择经手术和病理证实的胃肠道淋巴瘤患者30例,采用CT与胃肠道低张双对比造影的方法进行检查。结果:30例患者中,浸润型16例,占53.3%;肿块型11例,占36.7%;溃疡型2例,占6.7%;多发结节型1例,占3.3%,以浸润型最多见。其诊断结果与手术和病理诊断结果基本一致。结论:针刺低张双对比造影具有简便易行、无毒副作用等优点,并可扩大低张造影的适应症范围,为提高胃肠道淋巴瘤诊断正确率的有效方法。

Contrast-enhanced sonography versus biopsy for the differential diagnosis of thrombosis in hepatocellular carcinoma patients

AIM:To clarify which method has accuracy:2nd gen-eration contrast-enhanced ultrasound or biopsy of portal vein thrombus in the differential diagnosis of portal vein thrombosis.METHODS:One hundred and eighty-six patients with hepatocellular carcinoma and portal vein thrombosis underwent in blinded fashion a 2nd generation contrast-enhanced ultrasound and biopsy of portal vein thrombus;both results were examined on the basis of the follow-up of patients compared to reference-standard.RESULTS:One hundred and eight patients completed the study.Benign thrombosis on 2nd generation contrast-enhanced ultrasound was characterised by progressive hypoenhancing of the thrombus;in malignant portal vein thrombosis there was a precocious homo-geneous enhancement of the thrombus.On follow-up there were 50 of 108 patients with benign thrombosis:all were correctly diagnosed by both methods.There were 58 of 108 patients with malignant thrombosis:amongst these,52 were correctly diagnosed by both methods,the remainder did not present malignant cells on portal vein thrombus biopsy and showed on 2nd generation contrast-enhanced ultrasound an inho-mogeneous enhancement pattern.A new biopsy during the follow-up,guided to the area of thrombus that showed up on 2nd generation contrast-enhanced ultra-sound,demonstrated an enhancing pattern indicating malignant cells.CONCLUSION:In patients with hepatocellular carcinoma complicated by portal vein thrombosis,2nd generation contrast-enhanced ultrasound of portal vein thrombus is very useful in assessing the benign or malignant nature of the thrombus.Puncture biopsy of thrombus is usually accurate but presents some sampling errors,so,when pathological results are required,2nd generation contrast-enhanced ultrasound could guide the sampling needle to the correct area of the thrombus.

造影剂肾病发病机制研究进展

目前对造影剂肾病的发病机制还不完全清楚，虽然相关的动物和细胞实验研究较多，但临床研究偏少，认识不充分，而且多数动物实验为了成功建造CIN模型，都预先使用了损害肾脏的药物（如非甾体抗炎药等），因此不能完全模拟临床造影剂肾病的病理生理状态，同时也限制了这些研究结果推广到临床，希望今后能有更科学更严谨的研究关注于此。