Three artificial gynogenetic clones of silver carp were produced for the analysis of restriction enzyme digestion patterns of ND5-ND6 region from mtDNA of the clones. It is revealed that all intraclonal individuals sh...Three artificial gynogenetic clones of silver carp were produced for the analysis of restriction enzyme digestion patterns of ND5-ND6 region from mtDNA of the clones. It is revealed that all intraclonal individuals shared completely the same digestion patterns but among interclonal individuals did not. The three clones were mixed and cultured in a pond together for two years, and restriction endonuclease digestion patterns of ND5-ND6 were used as genetic markers to assess the growth performance of each clone.展开更多
Current knowledge of the origin and population history of Tibetan highlanders is still very much in its infancy and controversial.Who are the Tibetans?How long have they been living on the Tibetan Plateau,the 'Roo...Current knowledge of the origin and population history of Tibetan highlanders is still very much in its infancy and controversial.Who are the Tibetans?How long have they been living on the Tibetan Plateau,the 'Roof of the World'?Who were the early highlanders?Were they modern human or non-modern human species?Whether is there a genetic continuity,展开更多
Research led by scientists from University College London(UCL),Queen Mary University of London(QMUL)and Dr.Andrew E.Teschendorff from the CAS-MPG Partner Institute for Computational Biology(PICB),Shanghai Institutes f...Research led by scientists from University College London(UCL),Queen Mary University of London(QMUL)and Dr.Andrew E.Teschendorff from the CAS-MPG Partner Institute for Computational Biology(PICB),Shanghai Institutes for Biological Sciences(SIBS),Chinese Academy of Sciences(CAS)has identified epigenetic changes in three types of immune cells that展开更多
文摘旨在探讨鸡不同杂交组合线粒体控制区(mtDNA D-loop区)的遗传多样性和单倍型特性。选取固始鸡和隐性白羽鸡及其正、反交F1代、藏鸡以及F2代等6个群体共387个个体的mtDNA D-loop区进行测序,分析其遗传规律和单倍型特性,并与不同红色原鸡亚种进行聚类,分析其母系起源。结果显示,6个群体D-loop区全序列大小为1 231 bp,共检测到28个多态位点和1个C碱基缺失,共构成19种单倍型,分为A、B、C和E 4个单倍型群,其中,固始鸡和反交F1代主要为A、C单倍型,固始鸡A、C单倍型比例分别为53.42%和46.58%,反交F1代A、C单倍型比例分别为50.75%和49.25%;隐性白羽鸡、正交F1代和F2代优势单倍型均为E单倍型,占比分别为 48.89%、48.84%和50.00%。6个鸡群体单倍型多样度( Hd )在0.496~0.729之间,核苷酸多样度( Pi )在0.003 40 ~0.005 41之间, Hd 值和 Pi 值最大的均为正交F1代,其次为隐性白羽鸡和F2代,固始鸡和反交F1代群体遗传多样性接近。聚类分析显示,A、B单倍型群与滇南亚种交叉聚为一枝;E单倍型群与印度亚种交叉聚为一枝;C单倍型群与印度亚种、指名亚种、印尼亚种以及滇南亚种聚为一枝。结果提示,mtDNA D-loop区遵循严格的母系遗传,后代的遗传多样性和单倍型比例与其母本基本一致;我国家鸡群体具有多个红色原鸡母系起源,且主要起源于原鸡滇南亚种。
基金Project supported by the National Natural Science Foundation of China (No. 39830300).
文摘Three artificial gynogenetic clones of silver carp were produced for the analysis of restriction enzyme digestion patterns of ND5-ND6 region from mtDNA of the clones. It is revealed that all intraclonal individuals shared completely the same digestion patterns but among interclonal individuals did not. The three clones were mixed and cultured in a pond together for two years, and restriction endonuclease digestion patterns of ND5-ND6 were used as genetic markers to assess the growth performance of each clone.
基金Supported by the Strategic Priority Research Program of the Chinese Academy of SciencesNational Natural Science Foundation of China grantsthe Science and Technology Commission of Shanghai Municipality
文摘Current knowledge of the origin and population history of Tibetan highlanders is still very much in its infancy and controversial.Who are the Tibetans?How long have they been living on the Tibetan Plateau,the 'Roof of the World'?Who were the early highlanders?Were they modern human or non-modern human species?Whether is there a genetic continuity,
基金the International Human Epigenome Consortium(IHEC)of which the EU-FP7 Project BLUEPRINT is a memberfunded by SIBS+1 种基金sponsored by CASthe Royal Society Newton International Fellowship
文摘Research led by scientists from University College London(UCL),Queen Mary University of London(QMUL)and Dr.Andrew E.Teschendorff from the CAS-MPG Partner Institute for Computational Biology(PICB),Shanghai Institutes for Biological Sciences(SIBS),Chinese Academy of Sciences(CAS)has identified epigenetic changes in three types of immune cells that
