An analytical method in a quasi-static fiber grating sensing system under transverse uniform press is proposed based on genetic algorithm The effect of population size, generations, crossover ratio and mutation ratio ...An analytical method in a quasi-static fiber grating sensing system under transverse uniform press is proposed based on genetic algorithm The effect of population size, generations, crossover ratio and mutation ratio to genetic algorithm, and the optimization parameters of genetic algorithm were given. The relevant experimental system is constructed. The simulation and experiments show that the analytical method proposed can be applied to analyze the reflective spectra of the quasistatic FBG sensing system at transverse uniform press, the strain measurement with high-precision of 0.91% can be realized展开更多
Ibn Batuta＇s book The Rihla gives us a unique insight into life of a 14th C travelling scholar in the golden age of Dar AI Islam （the world of Islam）. This paper is a reflection on Ibn Battuta focusing on three cur...Ibn Batuta＇s book The Rihla gives us a unique insight into life of a 14th C travelling scholar in the golden age of Dar AI Islam （the world of Islam）. This paper is a reflection on Ibn Battuta focusing on three curious things we don＇t know about him. First, we don＇t know what he looks like--what does this tell us about visual culture, ethnicity and the idea of self-image in 14th Century. Second, we don＇t know if he really went to China--if not why would this section be included？ Third, we don＇t know how his story became lost to history, which it certainly was for close to 400 years--what does this tell us about the man, the book, it＇s intended audience and the changes happening within Dar AI Islam at that time.展开更多
Objective To investigate the interaction between the genes required for the functions of AWA olfactory neuron and insulin/IGF signaling in regulating the longevity of nematode Caenorhabditis elegans （C. elegans）. Me...Objective To investigate the interaction between the genes required for the functions of AWA olfactory neuron and insulin/IGF signaling in regulating the longevity of nematode Caenorhabditis elegans （C. elegans）. Methods The mutants that had loss-of-function mutation of the genes required for AWA, AWC, ASE, and AFD sensory neurons were employed. Lifespan, the speed of pharynx pumping, the intestinal autofluorescence, the dauer formation, and the brood size were examined. Rescue experiments were performed to confrm the role of the genes required for the functions of AWA neuron in regulating lifespan. Moreover, genetic interactions between genes required for the functions of AWA neuron and insulin/ IGF signaling were investigated. Results Mutations of odr-7, odr-2, and odr-3 genes required for the functions of AWA neuron significantly increased the mean lifespan of nematodes and slowed the accumulation of intestinal autofluorescence. Besides, these mutations were closely associated with higher pumping rates during aging. However, mutation of odr-7, odr- 2, or odr-3 did not obviously affect the brood size or the dauer formation, and the regulation of longevity by odr-7, odr-2, and odr-3 was temperature-independent. In contrast, mutations of genes required for the functions of ASE, AWC, and AFD sensory neurons did not infuence the nematode lifespan. Moreover, expression of odr-7, odr-2 and odr-3 in AWA neuron could completely or largely restore the altered lifespan in odr-7, odr-2 and odr-3 mutants. Furthermore, genetic interaction assay demonstrated that the extended lifespan in odr-7 mutant could be suppressed by daf-16 mutation and enhanced by daf- 2 or age-1 mutation, whereas mev-1 and pha-4 were not required for the long lifespan of odr-7 mutant. Conclusion The genes required for the function of AWA sensory neuron could regulate the nematode longevity in an insulin/IGF signaling-dependent fashion in C. elegans.展开更多
Objective： To investigate the community promotion feasibility of superficial needling plus club swing for post-stroke motion impairment of the shoulder joint. Methods：A total of 180 cases （duration 〈1.5 years） wi...Objective： To investigate the community promotion feasibility of superficial needling plus club swing for post-stroke motion impairment of the shoulder joint. Methods：A total of 180 cases （duration 〈1.5 years） with post-stroke motion impairment of the shoulder joint were recruited from three community health centers in Changning District, 60 from each community. They were randomly allocated into an observation group （n=90） and a control group （n=90）. Patients in both groups received standard internal and rehabilitation care. Patients in the observation group received additional superficial needling plus club swing. The visual analogue scale （VAS） was conducted before and 60 d after the treatment to evaluate the severity of shoulder pain. The active movement of the shoulder joint and activities of daily living （ADL） were also observed. Results：There were no between-group statistical differences before the treatment （allP〉0.05）. After a 60-day treatment, the shoulder pain severity, active range of motion of the shoulder joint and ADL in the observation group were significantly improved than those in the control group （allP〈0.01）. In addition, no adverse events were reported by participants in the observation group. Conclusion：Superficial needling plus club swing plays a positive role in improving post-stroke motion impairment of the shoulder joint. This safe, reliable and economical therapy has good patient compliance and is suitable for community promotion.展开更多
文摘An analytical method in a quasi-static fiber grating sensing system under transverse uniform press is proposed based on genetic algorithm The effect of population size, generations, crossover ratio and mutation ratio to genetic algorithm, and the optimization parameters of genetic algorithm were given. The relevant experimental system is constructed. The simulation and experiments show that the analytical method proposed can be applied to analyze the reflective spectra of the quasistatic FBG sensing system at transverse uniform press, the strain measurement with high-precision of 0.91% can be realized
文摘Ibn Batuta＇s book The Rihla gives us a unique insight into life of a 14th C travelling scholar in the golden age of Dar AI Islam （the world of Islam）. This paper is a reflection on Ibn Battuta focusing on three curious things we don＇t know about him. First, we don＇t know what he looks like--what does this tell us about visual culture, ethnicity and the idea of self-image in 14th Century. Second, we don＇t know if he really went to China--if not why would this section be included？ Third, we don＇t know how his story became lost to history, which it certainly was for close to 400 years--what does this tell us about the man, the book, it＇s intended audience and the changes happening within Dar AI Islam at that time.
基金supported by the National Natural Science Foundation of China (No. 30771113,30870810)the Program for New Century Excellent Talents in University
文摘Objective To investigate the interaction between the genes required for the functions of AWA olfactory neuron and insulin/IGF signaling in regulating the longevity of nematode Caenorhabditis elegans （C. elegans）. Methods The mutants that had loss-of-function mutation of the genes required for AWA, AWC, ASE, and AFD sensory neurons were employed. Lifespan, the speed of pharynx pumping, the intestinal autofluorescence, the dauer formation, and the brood size were examined. Rescue experiments were performed to confrm the role of the genes required for the functions of AWA neuron in regulating lifespan. Moreover, genetic interactions between genes required for the functions of AWA neuron and insulin/ IGF signaling were investigated. Results Mutations of odr-7, odr-2, and odr-3 genes required for the functions of AWA neuron significantly increased the mean lifespan of nematodes and slowed the accumulation of intestinal autofluorescence. Besides, these mutations were closely associated with higher pumping rates during aging. However, mutation of odr-7, odr- 2, or odr-3 did not obviously affect the brood size or the dauer formation, and the regulation of longevity by odr-7, odr-2, and odr-3 was temperature-independent. In contrast, mutations of genes required for the functions of ASE, AWC, and AFD sensory neurons did not infuence the nematode lifespan. Moreover, expression of odr-7, odr-2 and odr-3 in AWA neuron could completely or largely restore the altered lifespan in odr-7, odr-2 and odr-3 mutants. Furthermore, genetic interaction assay demonstrated that the extended lifespan in odr-7 mutant could be suppressed by daf-16 mutation and enhanced by daf- 2 or age-1 mutation, whereas mev-1 and pha-4 were not required for the long lifespan of odr-7 mutant. Conclusion The genes required for the function of AWA sensory neuron could regulate the nematode longevity in an insulin/IGF signaling-dependent fashion in C. elegans.
基金supported by Appropriate Technology of Traditional Chinese Medicine Promotion Project in the Community of Shanghai No.ZYSNXD-YL-SYJS-2Special Project of Science and Technology Committee of Changning District in Shanghai No.CNKW2014J06~~
文摘Objective： To investigate the community promotion feasibility of superficial needling plus club swing for post-stroke motion impairment of the shoulder joint. Methods：A total of 180 cases （duration 〈1.5 years） with post-stroke motion impairment of the shoulder joint were recruited from three community health centers in Changning District, 60 from each community. They were randomly allocated into an observation group （n=90） and a control group （n=90）. Patients in both groups received standard internal and rehabilitation care. Patients in the observation group received additional superficial needling plus club swing. The visual analogue scale （VAS） was conducted before and 60 d after the treatment to evaluate the severity of shoulder pain. The active movement of the shoulder joint and activities of daily living （ADL） were also observed. Results：There were no between-group statistical differences before the treatment （allP〉0.05）. After a 60-day treatment, the shoulder pain severity, active range of motion of the shoulder joint and ADL in the observation group were significantly improved than those in the control group （allP〈0.01）. In addition, no adverse events were reported by participants in the observation group. Conclusion：Superficial needling plus club swing plays a positive role in improving post-stroke motion impairment of the shoulder joint. This safe, reliable and economical therapy has good patient compliance and is suitable for community promotion.
