[Objective] The aim was to analyze sugar components in fermented rice wine by ion chromatography. [Method] The optimal condition for chromatography system of sugar analysis was selected by measuring sugars in fermente...[Objective] The aim was to analyze sugar components in fermented rice wine by ion chromatography. [Method] The optimal condition for chromatography system of sugar analysis was selected by measuring sugars in fermented rice wine with ion chromatography and pulsed amperometric detection. [Result] The optimal measurement conditions were as follows: Leacheate (Leachate), consisting of NaOH and CH3COONa, was eluted by gradient concentrations, with column temperature at 35 ℃ and flow rate at 0.4 ml/min. In the condition, sugars in rice wine were ana- lyzed and the results showed that the method is featured by low detection limit, good repetition and high recovery rate. [Conclusion] The research establishes and determines the approaches and optimum conditions for sugar analysis in rice wine by ion chromatography and pulsed amperometric detection, providing references for advancement of research on quality improvement of fermented rice wine.展开更多
Since there are many factors affecting the quality of wine, total 17 factors were screened out using principle component analysis. The difference test was conducted on the evaluation data of the two groups of testers....Since there are many factors affecting the quality of wine, total 17 factors were screened out using principle component analysis. The difference test was conducted on the evaluation data of the two groups of testers. The results showed that the evaluation data of the second group were more reliable compared with those of the first group. At the same time, the KM algorithm was optimized using the QPSO algorithm. The wine classification model was established. Compared with the other two algorithms, the QPSO-KM algorithm was more capable of searching the globally optimum solution, and it could be used to classify the wine samples. In addition,the QPSO-KM algorithm could also be used to solve the issues about clustering.展开更多
Objective] This study was conducted to further explore the diversity of Saccharomyces cerevisiae_from Chateau Changyu Moser XV and realize better de-velopment and utilization of Saccharomyces cerevisiae resources. [Me...Objective] This study was conducted to further explore the diversity of Saccharomyces cerevisiae_from Chateau Changyu Moser XV and realize better de-velopment and utilization of Saccharomyces cerevisiae resources. [Method] ln this study, the wine grape regions of Chateau Changyu Moser XV were taken as the research object. The Saccharomycetes_in the soil was isolated, screened and ob-served in the natural fermentation process of grape berry epidermis and the fruit. The 32 Saccharomycetes strains were preliminarily classified based on WL nutrient agar, and 26S rDNA D1/D2 sequence analysis was conducted. [Result] Total y, 4 kinds of Saccharomycetes were identified in this study, including Pichia kluyveri, Hanseniaspora uvarum, Saccharomyces cerevisiae_and Cryptococcus magnus. [Con-clusion] The main species of Saccharomycetes in the wine grape region of Chateau Changyu Moser XV were preliminarily determined, which provides theoretical basis and research basis for the brewing of wine with special characteristics.展开更多
A method for preparing D-valine from L-valine by racemization and chemical resolution is presented. The resolving reagent, D-2,3-dibenzoyl tartaric acid was obtained by hydrolyzation of D-2,3-dibenzoyl tartaric anhydr...A method for preparing D-valine from L-valine by racemization and chemical resolution is presented. The resolving reagent, D-2,3-dibenzoyl tartaric acid was obtained by hydrolyzation of D-2,3-dibenzoyl tartaric anhydride prepared by reaction of benzoyl chloride with D-tartaric acid. DL-valine was prepared by racemization of L-valine in the presence of aldehyde in a medium of acetic acid at 100 to 110°C for 3 h. In the presence of mineral acid, reaction of D-2,3-dibenzoyl tartaric acid with DL-valine formed diastreroisomeric salts at 84 to 95°C. Salt composed of D-2,3-dibenzoyl tartaric acid and D-valine precipitated when the diastreroisomeric salts mixtures were cooled to 15°C. The salt was reacted with base giving D-valine with yield of 70% to 80% and optical purity of over 98%.展开更多
AIM: To identify risk factors for nonalcoholic steatohepatitis following pancreaticoduodenectomy, with a focus on factors related to pancreatic secretions. METHODS: The medical records of 228 patients who had a pancre...AIM: To identify risk factors for nonalcoholic steatohepatitis following pancreaticoduodenectomy, with a focus on factors related to pancreatic secretions. METHODS: The medical records of 228 patients who had a pancreaticoduodenectomy over a 16-mo period were reviewed retrospectively. The 193 patients who did not have fatty liver disease preoperatively were included in the final analysis. Hepatic steatosis was diagnosed using the differences between splenic and hepatic attenuation and liver-to-spleen attenuation as measured by non-enhanced computed tomography. RESULTS: Fifteen patients (7.8%) who showed postoperative hepatic fatty changes were assigned to Group A, and the remaining patients were assigned to Group B. Patient demographics, preoperative laboratory findings (including levels of C-peptide, glucagon, insulin and glucose tolerance test results), operation types, and final pathological findings did not differ significantly between the two groups; however, the frequency of pancreatic fistula (P = 0.020) and the method of pancreatic duct stenting (P = 0.005) showed significant differences between the groups. A multivari- ate analysis identified pancreatic fistula (HR = 3.332, P = 0.037) and external pancreatic duct stenting (HR = 4.530, P = 0.017) as independent risk factors for the development of postoperative steatohepatitis. CONCLUSION: Pancreatic fistula and external pancreatic duct stenting were identified as independent risk factors for the development of steatohepatitis following pancreaticoduodenectomy.展开更多
AIM:To evaluate the noninvasive parameters and hepatic fibrosis scores in obese children with nonalcoholic fatty liver disease(NAFLD).METHODS:A total of 77 children diagnosed with NAFLD via liver biopsy were included ...AIM:To evaluate the noninvasive parameters and hepatic fibrosis scores in obese children with nonalcoholic fatty liver disease(NAFLD).METHODS:A total of 77 children diagnosed with NAFLD via liver biopsy were included and divided into 2 subgroups according to the histopathologic staging of hepatic fibrosis:mild(stage 0-1)vs significant fibrosis(stage 2-4).Clinical and laboratory parameters were evaluated in each patient.The aspartate aminotransferase(AST)/alanine aminotransferase(ALT)ratio,AST/platelet ratio index(APRI),PGA index,Forns index,FIB-4,NAFLD fibrosis score,and pediatric NAFLD fibrosis index(PNFI)were calculated.RESULTS:No clinical or biochemical parameter exhibited a significant difference between patients with mild and significant fibrosis.Among noninvasive hepatic fibrosis scores,only APRI and FIB4 revealed a significant difference between patients with mild and significant fibrosis(APRI:0.67±0.54 vs 0.78±0.38,P=0.032 and FIB4:0.24±0.12 vs 0.31±0.21,P=0.010).The area under the receiving operating characteristic curve of FIB4 was 0.81,followed by Forns index(0.73),APRI(0.70),NAFLD fibrosis score(0.58),AST/ALT ratio(0.53),PGA score(0.45),and PNFI(0.41).CONCLUSION:APRI and FIB4 might be useful noninvasive hepatic fibrosis scores for predicting hepatic fibrosis in children with NAFLD.展开更多
The reasonable development and utilization of mountainous regions closely relates to local economic development and ecological security. The wine production region in the eastern foothills of the Helan Mountains in Ni...The reasonable development and utilization of mountainous regions closely relates to local economic development and ecological security. The wine production region in the eastern foothills of the Helan Mountains in Ningxia, Ningxia Hui Autonomous Region, with its excellent terroir, is emerging as one of China's three major geographical attractions. Based on surveys of tourism resources and spatial analysis for this wine producing region, we propose a highly representative and practicable path for wine tourism development. Based on China's national standard in Classification, Investigation and Evaluation of Tourism Resources(GB/T 18972-2003), which recommended the types and grades of tourism resources in one area, we conduct an analysis of resource characteristics and the current state of development. Using Arc GIS software, spatialautocorrelation analysis, average nearest neighbor analysis, as well as clustering and outlier analysis, we are able to derive the spatial distribution characteristics of tourism resources. Our survey showed that tourism resources in this area are relatively abundant and have good quality and clear combination advantages. Nonetheless, there are resources shortage for wine tourism and poor integration of wine production with the tourism industry. Regarding the spatial distribution of resources, we revealed the current states of and issues surrounding regions with concentrated resources, as well as characteristics of this clustering. Finally, we proposed a development path for wine tourism in this region based on the five dimensions of management mode, industrial path, product development, spatial optimization, and market development.展开更多
Distribution behavior of ketoprofen enantiomers was examined in methanol aqueous and organic solvent mixture containing tartaric esters. The influence of length of alkyl chain of tartaric esters, concentration of L-ta...Distribution behavior of ketoprofen enantiomers was examined in methanol aqueous and organic solvent mixture containing tartaric esters. The influence of length of alkyl chain of tartaric esters, concentration of L-tartaric esters and methanol aqueous, kind of organic solvent on partition ratio and separation factors was investigated. The results show that L-tartaric and D-tartaric esters have different chiral recognition abilities. S-ketoprofen is easily extracted by L-tartaric esters, and R-ketoprofen is easily extracted by D-tartaric esters. L-tartaric esters form more stable diastereomeric complexes with S-enantiomer than that with R-enantiomer. This distribution behavior is consistent with chiral recognition mechanism. With the increase of the concentration of tartaric ester from 0 to 0.3 mol/L, partition coefficient K and separation factor a increase. Also, the kind of organic solvent and the concentration of the methanol aqueous have significant influence on K and a.展开更多
Objective To assess the relationships between iodine biological exposure and subclinical thyroid dysfunctions. Methods The cross-sectional survey was performed to obtain the epidemiologic data of population in three ...Objective To assess the relationships between iodine biological exposure and subclinical thyroid dysfunctions. Methods The cross-sectional survey was performed to obtain the epidemiologic data of population in three communities with different iodine biological exposure: mild iodine deficiency [median urinary iodine concentration (MUI) of 50-99 μg/L], more than adequate iodine intake (MUI of 200-299 μg/L), and excessive iodine intake (MUI over 300 μg/L). Univariate and multivariate analysis (logistic regression analysis) were used to analyze the risk factors of subclinical hypothyroidism and subclinical hyperthyroidism. Logistic regression analysis with sex and age controlled suggested that more than adequate iodine intake (OR = 3.172, P = 0.0004) and excessive iodine intake (OR = 6.391, P = 0.0001) increased the risk of subclinical hypothyroidism, while excessive iodine intake decreased the risk of subclinical hyperthyroidism (OR = 0.218, P= 0.0001). Logistic regression analysis including interaction of iodine intake and antibodies [tryroid peroxidase antibody (TPOAb) and thyroglobulin antibody (TgAb)] suggested that excessive iodine intake was an independent risk factor of subclinical hypothyroidism (OR = 6.360, P= 0.0001), but independent protect factor of subclinical hyperthyroidism (OR = 0.193, P= 0.0001). More than adequate iodine intake and it's interaction with TgAb increased the risk of subclinical hypothyroidism independently, in addition, it decreased the risk of subclinical hyperthyroidism at the present of TPOAb. Conclusion Both excessive iodine intake and more than adequate iodine intake could increase risk of subclinical hypothyroidism, supplement of iodine should be controlled to ensure MUI within the safe range.展开更多
For the four-bar beating-up mechanism of air-jet loom,the plain bearing of linkage is the bearing with dynamic load,and is immersed in the lubricant-box.If the joint clearance is considered,the research on linkage mov...For the four-bar beating-up mechanism of air-jet loom,the plain bearing of linkage is the bearing with dynamic load,and is immersed in the lubricant-box.If the joint clearance is considered,the research on linkage movement could be very complicated.In this paper,the kinematic characteristics of four-bar beating-up mechanism with joint clearance were studied by analyzing the trace of journal center and the balance of radial,tangential forces,and bearing load.The region of principal vibration and its forming causes were discussed.And the results could interpret the measuring curves of four-bar beating-up mechanism completely.展开更多
AIM: To explore the change of intestinal mucosa barrier function in the progress of non-alcoholic steatohepatitis (NASH) in rats. METHODS: Thirty-two Sprague-Dawley (SD) rats were randomly divided into control group a...AIM: To explore the change of intestinal mucosa barrier function in the progress of non-alcoholic steatohepatitis (NASH) in rats. METHODS: Thirty-two Sprague-Dawley (SD) rats were randomly divided into control group and model group. Rats in the control group were given normal diet, and rats in the model group were given fat-rich diet. Eight rats in each group were killed at end of the 8th and 12th wk, respectively. The levels of endotoxin, D-xylose, TG, TC, ALT and AST, intestinal tissue SOD and MDA as well as intestinal mucus secretory IgA (sIgA) were measured. The pathology of liver was observed by HE staining. RESULTS: At end of the 8th wk, there was no marked difference in the levels of endotoxin, D-xylose and sIgA between the two groups. At end of the 12th wk, rats in the model group developed steatohepatitis and had a higher serum level of endotoxin (P = 0.01) and D-xylose (P = 0.00) and a lower serum level of sIgA (P = 0.007). CONCLUSION: Intestinal mucosa barrier malfunction may exist in NASH rats and may be an important promoter of NASH in rats.展开更多
The impact of different phases of shipment (at sea and at port) on two German white wines of two vintages and the lasting effects of the temperature regimes over time was investigated. The wines were subjected to th...The impact of different phases of shipment (at sea and at port) on two German white wines of two vintages and the lasting effects of the temperature regimes over time was investigated. The wines were subjected to three temperature programs--control (15 ℃), linear increase (15℃ steadily increasing to 45 ℃), and diurnal fluctuation (15 ℃/40 ℃)--in both movement and non-movement conditions. The wines were analyzed for chemical, physical and sensorial changes at one and eight months post-treatment. Changes in temperature and pressure were recorded within the bottles, which correlated with the temperature programs: +0.04 bar/℃ in the linear increase program and +0.08 bar/℃ in the diurnal fluctuation program. The oxygen levels in the headspace and in the wine were monitored during all of the treatments. The oxygen development in the bottles was similar between the diurnal and linear programs, and was found to be distinctive from the control program. The chemical analysis revealed that there were significant differences related to the experimental treatments of the wines for the following parameters: tartaric acid, free sulfur dioxide, total sulfur dioxide and percent cork weight loss measurements. Difference sensory testing found very few differences. After eight months storage, significant differences were found in the Diurnal Non-movement treatment compared to Linear Non-movement and control treatments, as well as Diurnal Movement and Control treatments for the 2014 Miiller-Thurgau wine. Sensory descriptive analysis of the wines found that the wines could be differentiated by variety, but could not be distinguished according to experimental treatment after one month storage. These results indicate that wines of these types are more robust to shipping conditions than previously found.展开更多
[Objective] The aim was to to enhance the technology to brew better the traditional grape wine, which provided theoretical basis for the development of Wuling Mountain grape wine. [Method] Taking grapes in Wuling Moun...[Objective] The aim was to to enhance the technology to brew better the traditional grape wine, which provided theoretical basis for the development of Wuling Mountain grape wine. [Method] Taking grapes in Wuling Mountain as the row materials, Saccharomyces cerevisiae of different wines was chosen and brewed. The quality of grape wine was studied and the sensory evaluation was analyzed by dint of GC-MS. [Result] Result illustrated that the ethanol concentration of the wine brewed by exploration craft A was 68.5 g/L and that brewed by exploration craft B was 59.5 g/L; the higher alcohol content of craft A was 37.86% while that of craft B is 35.99%; craft A's percentage content of esters was 28.82% while that of B was 27.10%; craft A's percentage content of acids was 2.20% while that of B was 1.24%; the gamma-aminobutyric acid content of craft A was 33.2 g/100 ml while that of craft B was 35.4 g/100 ml. the essential amino-acid content of craft A was 11.8 g/100 ml while that of craft B was 13.9 g/100 ml .The result indicates that the wine brewed by craft A was aromatic and had special flavor. [Conclusion] In this case, the grape wine has particular flavor and has good property, which can be exploited.展开更多
基金Supported by Changsha Key Project in Hunan Province(K1005007-21)~~
文摘[Objective] The aim was to analyze sugar components in fermented rice wine by ion chromatography. [Method] The optimal condition for chromatography system of sugar analysis was selected by measuring sugars in fermented rice wine with ion chromatography and pulsed amperometric detection. [Result] The optimal measurement conditions were as follows: Leacheate (Leachate), consisting of NaOH and CH3COONa, was eluted by gradient concentrations, with column temperature at 35 ℃ and flow rate at 0.4 ml/min. In the condition, sugars in rice wine were ana- lyzed and the results showed that the method is featured by low detection limit, good repetition and high recovery rate. [Conclusion] The research establishes and determines the approaches and optimum conditions for sugar analysis in rice wine by ion chromatography and pulsed amperometric detection, providing references for advancement of research on quality improvement of fermented rice wine.
文摘Since there are many factors affecting the quality of wine, total 17 factors were screened out using principle component analysis. The difference test was conducted on the evaluation data of the two groups of testers. The results showed that the evaluation data of the second group were more reliable compared with those of the first group. At the same time, the KM algorithm was optimized using the QPSO algorithm. The wine classification model was established. Compared with the other two algorithms, the QPSO-KM algorithm was more capable of searching the globally optimum solution, and it could be used to classify the wine samples. In addition,the QPSO-KM algorithm could also be used to solve the issues about clustering.
基金Supported by Scientific Research Project of Ningxia Grape and Wine Technology Innovation Center(1505)District-level Undergraduate Innovation Program of Northem University for Nationalities(QJCX-2015-028)~~
文摘Objective] This study was conducted to further explore the diversity of Saccharomyces cerevisiae_from Chateau Changyu Moser XV and realize better de-velopment and utilization of Saccharomyces cerevisiae resources. [Method] ln this study, the wine grape regions of Chateau Changyu Moser XV were taken as the research object. The Saccharomycetes_in the soil was isolated, screened and ob-served in the natural fermentation process of grape berry epidermis and the fruit. The 32 Saccharomycetes strains were preliminarily classified based on WL nutrient agar, and 26S rDNA D1/D2 sequence analysis was conducted. [Result] Total y, 4 kinds of Saccharomycetes were identified in this study, including Pichia kluyveri, Hanseniaspora uvarum, Saccharomyces cerevisiae_and Cryptococcus magnus. [Con-clusion] The main species of Saccharomycetes in the wine grape region of Chateau Changyu Moser XV were preliminarily determined, which provides theoretical basis and research basis for the brewing of wine with special characteristics.
文摘A method for preparing D-valine from L-valine by racemization and chemical resolution is presented. The resolving reagent, D-2,3-dibenzoyl tartaric acid was obtained by hydrolyzation of D-2,3-dibenzoyl tartaric anhydride prepared by reaction of benzoyl chloride with D-tartaric acid. DL-valine was prepared by racemization of L-valine in the presence of aldehyde in a medium of acetic acid at 100 to 110°C for 3 h. In the presence of mineral acid, reaction of D-2,3-dibenzoyl tartaric acid with DL-valine formed diastreroisomeric salts at 84 to 95°C. Salt composed of D-2,3-dibenzoyl tartaric acid and D-valine precipitated when the diastreroisomeric salts mixtures were cooled to 15°C. The salt was reacted with base giving D-valine with yield of 70% to 80% and optical purity of over 98%.
文摘AIM: To identify risk factors for nonalcoholic steatohepatitis following pancreaticoduodenectomy, with a focus on factors related to pancreatic secretions. METHODS: The medical records of 228 patients who had a pancreaticoduodenectomy over a 16-mo period were reviewed retrospectively. The 193 patients who did not have fatty liver disease preoperatively were included in the final analysis. Hepatic steatosis was diagnosed using the differences between splenic and hepatic attenuation and liver-to-spleen attenuation as measured by non-enhanced computed tomography. RESULTS: Fifteen patients (7.8%) who showed postoperative hepatic fatty changes were assigned to Group A, and the remaining patients were assigned to Group B. Patient demographics, preoperative laboratory findings (including levels of C-peptide, glucagon, insulin and glucose tolerance test results), operation types, and final pathological findings did not differ significantly between the two groups; however, the frequency of pancreatic fistula (P = 0.020) and the method of pancreatic duct stenting (P = 0.005) showed significant differences between the groups. A multivari- ate analysis identified pancreatic fistula (HR = 3.332, P = 0.037) and external pancreatic duct stenting (HR = 4.530, P = 0.017) as independent risk factors for the development of postoperative steatohepatitis. CONCLUSION: Pancreatic fistula and external pancreatic duct stenting were identified as independent risk factors for the development of steatohepatitis following pancreaticoduodenectomy.
文摘AIM:To evaluate the noninvasive parameters and hepatic fibrosis scores in obese children with nonalcoholic fatty liver disease(NAFLD).METHODS:A total of 77 children diagnosed with NAFLD via liver biopsy were included and divided into 2 subgroups according to the histopathologic staging of hepatic fibrosis:mild(stage 0-1)vs significant fibrosis(stage 2-4).Clinical and laboratory parameters were evaluated in each patient.The aspartate aminotransferase(AST)/alanine aminotransferase(ALT)ratio,AST/platelet ratio index(APRI),PGA index,Forns index,FIB-4,NAFLD fibrosis score,and pediatric NAFLD fibrosis index(PNFI)were calculated.RESULTS:No clinical or biochemical parameter exhibited a significant difference between patients with mild and significant fibrosis.Among noninvasive hepatic fibrosis scores,only APRI and FIB4 revealed a significant difference between patients with mild and significant fibrosis(APRI:0.67±0.54 vs 0.78±0.38,P=0.032 and FIB4:0.24±0.12 vs 0.31±0.21,P=0.010).The area under the receiving operating characteristic curve of FIB4 was 0.81,followed by Forns index(0.73),APRI(0.70),NAFLD fibrosis score(0.58),AST/ALT ratio(0.53),PGA score(0.45),and PNFI(0.41).CONCLUSION:APRI and FIB4 might be useful noninvasive hepatic fibrosis scores for predicting hepatic fibrosis in children with NAFLD.
基金supported by the National Natural Science Foundation of China (Grant Nos. 41071110 41701620)
文摘The reasonable development and utilization of mountainous regions closely relates to local economic development and ecological security. The wine production region in the eastern foothills of the Helan Mountains in Ningxia, Ningxia Hui Autonomous Region, with its excellent terroir, is emerging as one of China's three major geographical attractions. Based on surveys of tourism resources and spatial analysis for this wine producing region, we propose a highly representative and practicable path for wine tourism development. Based on China's national standard in Classification, Investigation and Evaluation of Tourism Resources(GB/T 18972-2003), which recommended the types and grades of tourism resources in one area, we conduct an analysis of resource characteristics and the current state of development. Using Arc GIS software, spatialautocorrelation analysis, average nearest neighbor analysis, as well as clustering and outlier analysis, we are able to derive the spatial distribution characteristics of tourism resources. Our survey showed that tourism resources in this area are relatively abundant and have good quality and clear combination advantages. Nonetheless, there are resources shortage for wine tourism and poor integration of wine production with the tourism industry. Regarding the spatial distribution of resources, we revealed the current states of and issues surrounding regions with concentrated resources, as well as characteristics of this clustering. Finally, we proposed a development path for wine tourism in this region based on the five dimensions of management mode, industrial path, product development, spatial optimization, and market development.
基金Project(20376085) supportecd by the National Natural Science Foundation of China
文摘Distribution behavior of ketoprofen enantiomers was examined in methanol aqueous and organic solvent mixture containing tartaric esters. The influence of length of alkyl chain of tartaric esters, concentration of L-tartaric esters and methanol aqueous, kind of organic solvent on partition ratio and separation factors was investigated. The results show that L-tartaric and D-tartaric esters have different chiral recognition abilities. S-ketoprofen is easily extracted by L-tartaric esters, and R-ketoprofen is easily extracted by D-tartaric esters. L-tartaric esters form more stable diastereomeric complexes with S-enantiomer than that with R-enantiomer. This distribution behavior is consistent with chiral recognition mechanism. With the increase of the concentration of tartaric ester from 0 to 0.3 mol/L, partition coefficient K and separation factor a increase. Also, the kind of organic solvent and the concentration of the methanol aqueous have significant influence on K and a.
基金Supported by the National Natural Science Foundation of China(39970350 )and China Medical Board Fund (98-688 IITD).
文摘Objective To assess the relationships between iodine biological exposure and subclinical thyroid dysfunctions. Methods The cross-sectional survey was performed to obtain the epidemiologic data of population in three communities with different iodine biological exposure: mild iodine deficiency [median urinary iodine concentration (MUI) of 50-99 μg/L], more than adequate iodine intake (MUI of 200-299 μg/L), and excessive iodine intake (MUI over 300 μg/L). Univariate and multivariate analysis (logistic regression analysis) were used to analyze the risk factors of subclinical hypothyroidism and subclinical hyperthyroidism. Logistic regression analysis with sex and age controlled suggested that more than adequate iodine intake (OR = 3.172, P = 0.0004) and excessive iodine intake (OR = 6.391, P = 0.0001) increased the risk of subclinical hypothyroidism, while excessive iodine intake decreased the risk of subclinical hyperthyroidism (OR = 0.218, P= 0.0001). Logistic regression analysis including interaction of iodine intake and antibodies [tryroid peroxidase antibody (TPOAb) and thyroglobulin antibody (TgAb)] suggested that excessive iodine intake was an independent risk factor of subclinical hypothyroidism (OR = 6.360, P= 0.0001), but independent protect factor of subclinical hyperthyroidism (OR = 0.193, P= 0.0001). More than adequate iodine intake and it's interaction with TgAb increased the risk of subclinical hypothyroidism independently, in addition, it decreased the risk of subclinical hyperthyroidism at the present of TPOAb. Conclusion Both excessive iodine intake and more than adequate iodine intake could increase risk of subclinical hypothyroidism, supplement of iodine should be controlled to ensure MUI within the safe range.
文摘For the four-bar beating-up mechanism of air-jet loom,the plain bearing of linkage is the bearing with dynamic load,and is immersed in the lubricant-box.If the joint clearance is considered,the research on linkage movement could be very complicated.In this paper,the kinematic characteristics of four-bar beating-up mechanism with joint clearance were studied by analyzing the trace of journal center and the balance of radial,tangential forces,and bearing load.The region of principal vibration and its forming causes were discussed.And the results could interpret the measuring curves of four-bar beating-up mechanism completely.
文摘AIM: To explore the change of intestinal mucosa barrier function in the progress of non-alcoholic steatohepatitis (NASH) in rats. METHODS: Thirty-two Sprague-Dawley (SD) rats were randomly divided into control group and model group. Rats in the control group were given normal diet, and rats in the model group were given fat-rich diet. Eight rats in each group were killed at end of the 8th and 12th wk, respectively. The levels of endotoxin, D-xylose, TG, TC, ALT and AST, intestinal tissue SOD and MDA as well as intestinal mucus secretory IgA (sIgA) were measured. The pathology of liver was observed by HE staining. RESULTS: At end of the 8th wk, there was no marked difference in the levels of endotoxin, D-xylose and sIgA between the two groups. At end of the 12th wk, rats in the model group developed steatohepatitis and had a higher serum level of endotoxin (P = 0.01) and D-xylose (P = 0.00) and a lower serum level of sIgA (P = 0.007). CONCLUSION: Intestinal mucosa barrier malfunction may exist in NASH rats and may be an important promoter of NASH in rats.
文摘The impact of different phases of shipment (at sea and at port) on two German white wines of two vintages and the lasting effects of the temperature regimes over time was investigated. The wines were subjected to three temperature programs--control (15 ℃), linear increase (15℃ steadily increasing to 45 ℃), and diurnal fluctuation (15 ℃/40 ℃)--in both movement and non-movement conditions. The wines were analyzed for chemical, physical and sensorial changes at one and eight months post-treatment. Changes in temperature and pressure were recorded within the bottles, which correlated with the temperature programs: +0.04 bar/℃ in the linear increase program and +0.08 bar/℃ in the diurnal fluctuation program. The oxygen levels in the headspace and in the wine were monitored during all of the treatments. The oxygen development in the bottles was similar between the diurnal and linear programs, and was found to be distinctive from the control program. The chemical analysis revealed that there were significant differences related to the experimental treatments of the wines for the following parameters: tartaric acid, free sulfur dioxide, total sulfur dioxide and percent cork weight loss measurements. Difference sensory testing found very few differences. After eight months storage, significant differences were found in the Diurnal Non-movement treatment compared to Linear Non-movement and control treatments, as well as Diurnal Movement and Control treatments for the 2014 Miiller-Thurgau wine. Sensory descriptive analysis of the wines found that the wines could be differentiated by variety, but could not be distinguished according to experimental treatment after one month storage. These results indicate that wines of these types are more robust to shipping conditions than previously found.
基金Supported by Wuling Mountaionus Area Study Center Opening Fund( WLYF-2012002)
文摘[Objective] The aim was to to enhance the technology to brew better the traditional grape wine, which provided theoretical basis for the development of Wuling Mountain grape wine. [Method] Taking grapes in Wuling Mountain as the row materials, Saccharomyces cerevisiae of different wines was chosen and brewed. The quality of grape wine was studied and the sensory evaluation was analyzed by dint of GC-MS. [Result] Result illustrated that the ethanol concentration of the wine brewed by exploration craft A was 68.5 g/L and that brewed by exploration craft B was 59.5 g/L; the higher alcohol content of craft A was 37.86% while that of craft B is 35.99%; craft A's percentage content of esters was 28.82% while that of B was 27.10%; craft A's percentage content of acids was 2.20% while that of B was 1.24%; the gamma-aminobutyric acid content of craft A was 33.2 g/100 ml while that of craft B was 35.4 g/100 ml. the essential amino-acid content of craft A was 11.8 g/100 ml while that of craft B was 13.9 g/100 ml .The result indicates that the wine brewed by craft A was aromatic and had special flavor. [Conclusion] In this case, the grape wine has particular flavor and has good property, which can be exploited.