Eight N 5 (3 carboxy 1,2,4 triazolyl) N ′ aroyl ureas have been synthesized from 3 amino 1,2,4 triazolyl 5 carboxylic acid and substituted benzoylisocyanates in yields of 59 6%～55 9% with mp>300 ℃. The structure...Eight N 5 (3 carboxy 1,2,4 triazolyl) N ′ aroyl ureas have been synthesized from 3 amino 1,2,4 triazolyl 5 carboxylic acid and substituted benzoylisocyanates in yields of 59 6%～55 9% with mp>300 ℃. The structures of the title compounds were confirmed by IR, 1H NMR and elemental analysis. The room temperature biological activity tests showed that some target compounds have a good activity as plant growth regulator, the best of them appeared compounds Ⅱ b and Ⅱ c(for auxin).展开更多
Chlorothalonil 1 was treated with anhydrous KF in DMF at 110 ℃ to give the corresponding crystalline fluorine-containing 1,3-benzenedicarbonitrile 2. KF was used in an equivalent to the number of chlorine atoms to be...Chlorothalonil 1 was treated with anhydrous KF in DMF at 110 ℃ to give the corresponding crystalline fluorine-containing 1,3-benzenedicarbonitrile 2. KF was used in an equivalent to the number of chlorine atoms to be substituted. Compound 2 was subsequently reacted with ammonia to yield compound 3. In addition, halobenzamide 4 were refluxed with oxalyl chloride in anhydrous 1,2-dichloroethane(DCE) to yield benzoylisocyanates 5. Finally, seven novel BPUs chitin inhibitors 6a—6g were synthesized via the selective reaction of compound 3 with benzoylisocyanate derivatives 5, the total yield is over 30%—50%.展开更多
Seven novel N-(5-tetrazolyl) -N-(aryloxyacetyl)ureas have been synthesized by the additive reaction of 5-amino-1H-1,2,3,4-tetrazole with aryloxyacetyl isocyanate. Their structures were confirmed by IR, 1H NMR and el...Seven novel N-(5-tetrazolyl) -N-(aryloxyacetyl)ureas have been synthesized by the additive reaction of 5-amino-1H-1,2,3,4-tetrazole with aryloxyacetyl isocyanate. Their structures were confirmed by IR, 1H NMR and elemental analysis. The biological activity tests show the target compounds have a good activity as plant growth regulator, and N-(5-tetrazolyl)-N-(3-chlorophenyloxyacetyl)-urea and N-(5-tetrazolyl)-N-(1-naphthyloxyacetyl)-urea have a activity close to cytokinin.展开更多
文摘Eight N 5 (3 carboxy 1,2,4 triazolyl) N ′ aroyl ureas have been synthesized from 3 amino 1,2,4 triazolyl 5 carboxylic acid and substituted benzoylisocyanates in yields of 59 6%～55 9% with mp>300 ℃. The structures of the title compounds were confirmed by IR, 1H NMR and elemental analysis. The room temperature biological activity tests showed that some target compounds have a good activity as plant growth regulator, the best of them appeared compounds Ⅱ b and Ⅱ c(for auxin).
文摘Chlorothalonil 1 was treated with anhydrous KF in DMF at 110 ℃ to give the corresponding crystalline fluorine-containing 1,3-benzenedicarbonitrile 2. KF was used in an equivalent to the number of chlorine atoms to be substituted. Compound 2 was subsequently reacted with ammonia to yield compound 3. In addition, halobenzamide 4 were refluxed with oxalyl chloride in anhydrous 1,2-dichloroethane(DCE) to yield benzoylisocyanates 5. Finally, seven novel BPUs chitin inhibitors 6a—6g were synthesized via the selective reaction of compound 3 with benzoylisocyanate derivatives 5, the total yield is over 30%—50%.
文摘Seven novel N-(5-tetrazolyl) -N-(aryloxyacetyl)ureas have been synthesized by the additive reaction of 5-amino-1H-1,2,3,4-tetrazole with aryloxyacetyl isocyanate. Their structures were confirmed by IR, 1H NMR and elemental analysis. The biological activity tests show the target compounds have a good activity as plant growth regulator, and N-(5-tetrazolyl)-N-(3-chlorophenyloxyacetyl)-urea and N-(5-tetrazolyl)-N-(1-naphthyloxyacetyl)-urea have a activity close to cytokinin.
