酶促酮酸酯还原合成(S)-2-乙酰氧基十三烷

S)-2-Acetoxyltridecane, which is the aggregation pheromone of Drosophila Mulleric and the sex pheromone component of the pea midge (Contarinia pisi), was synthesized from ethyl acetoacetate by enzymatic reduction with bakers yeast in the presence of ethyl chloroacetate as a key step. The optical purity of the target product is about 98%e.e.

亚硒酸钠对心血管疾病的影响

硒是人和动物的必需微量元素,作为谷胱甘肽过氧化物酶(GPX)的活性中心组分,参与机体脂质过氧化物和过氧化氢的酶促还原反应,在机体的抗过氧化作用中起重要作用。血小板富含硒和GPX,均受饮食硒水平的影响。心肌含硒量亦较高,主要存在于肌球蛋白中,DNA和RNA中均含硒。硒及其化合物亚硒酸钠通过抗氧化作用和改变血小板功能及花生四烯酸代谢而影响心血管功能。