期刊文献+
共找到3篇文章
< 1 >
每页显示 20 50 100
孟鲁司特钠片酸降解未知杂质结构及来源分析 被引量:1
1
作者 张琳琳 刘阿利 +2 位作者 张继环 王雪 张贵民 《中南药学》 CAS 2022年第7期1564-1568,共5页
目的对孟鲁司特钠片酸降解试验中出现的两个未知杂质峰进行结构及来源分析,以保证药品质量与安全。方法采用Waters XBridge phenyl柱(4.6 mm×150 mm,3.5μm),以0.01 mol·L^(-1)醋酸铵(用冰醋酸调节pH值至5.5)-乙腈(45∶55)为... 目的对孟鲁司特钠片酸降解试验中出现的两个未知杂质峰进行结构及来源分析,以保证药品质量与安全。方法采用Waters XBridge phenyl柱(4.6 mm×150 mm,3.5μm),以0.01 mol·L^(-1)醋酸铵(用冰醋酸调节pH值至5.5)-乙腈(45∶55)为流动相对孟鲁司特钠片酸降解未知杂质进行分离,电喷雾离子源正负离子模式测定未知杂质分子量,进行结构鉴定;通过高效液相色谱进一步确认未知杂质结构和来源。结果2个未知杂质为同一分子结构的两种存在型式,且为孟鲁司特钠与溶剂甲醇反应所得,并非孟鲁司特钠片自身酸降解产物。结论通过对孟鲁司特钠片酸降解未知杂质进行研究,为后续质量控制提供参考和指导。 展开更多
关键词 高效液相色谱串联质谱法 高效液相色谱法 孟鲁司特钠片 酸降解试验 未知杂质
下载PDF
Phthalate Esters Biodegradation by Fusarium Oxysporum in Vegetable Soil 被引量:1
2
作者 LV Hui-ying LI Gao-yang +3 位作者 FANG Zhi-hui ZHANG Fan LIANG Zeng-enni SHAN Yang 《Agricultural Science & Technology》 CAS 2018年第3期52-57,共6页
In this research, soil samples were frst polluted with 6 PAEs (i.e. DMP, DEP, DIBP, DBP, DEHP, and BBP) at 3 different concentration gradients (0, 10, and 20 mg/kg) and then treated with a highly-efficient degrada... In this research, soil samples were frst polluted with 6 PAEs (i.e. DMP, DEP, DIBP, DBP, DEHP, and BBP) at 3 different concentration gradients (0, 10, and 20 mg/kg) and then treated with a highly-efficient degradation fungus, Fusarium oxysporum (PO-Yi), to investigate the biodegradation of PAEs in pepper and eggplant soil. The findings revealed that PO-Yi can accelerate the degradation of PAEs in vegetable soils including pepper and eggplant soil to varying degrees. The highest absolute degradation rate (up to 39.5%) was observed in DEP-treated soils at the high pollution level (20 mg/kg), which was 14.2% higher than that at the middle pollution level (10 mg/kg). The degradation effect in the pepper soil was superior to that in the eggplant soil. Vegetable soil, either pepper soil or eggplant soil, which was polluted by various PAEs at different pollution gradients and then treated with PO-Yi fungus presented good bioremediation results. In the pepper and eggplant soil, 76.8% and 63.1% of the PAEs with a total volume of 60 mg/kg were degraded within 30 d respectively. PO-Yi, indigenous microorganisms, and the vegetables, i.e. pepper and eggplant had good synergistic effects on the degradation of compound PAEs in PAE-polluted pot soil. 展开更多
关键词 Fusarium oxysporum (PO-Yi) PHTHALATES SOIL BIODEGRADATION Pot experiment
下载PDF
Phthalate Esters Biodegradation by Fusarium oxysporum in Vegetable Soil
3
作者 LV Hui-ying LI Gao-yang +3 位作者 FANG Zhi-hui ZHANG Fan LIANG Zeng-enni SHAN Yang 《Agricultural Science & Technology》 CAS 2019年第1期37-41,54,共6页
In this research, soil samples were first polluted with 6 PAEs (i.e. DMP, DEP, DIBP, DBP, DEHP, and BBP) at 3 different concentration gradients (0, 10, and 20 mg/kg) and then treated with a highly-efficient degradatio... In this research, soil samples were first polluted with 6 PAEs (i.e. DMP, DEP, DIBP, DBP, DEHP, and BBP) at 3 different concentration gradients (0, 10, and 20 mg/kg) and then treated with a highly-efficient degradation fungus, Fusarium oxysporum (PO-Yi), to investigate the biodegradation of PAEs in pepper and eggplant soil. The findings revealed that PO-Yi can accelerate the degradation of PAEs in vegetable soils including pepper and eggplant soil to varying degrees. The highest absolute degradation rate (up to 39.5%) was observed in DEP-treated soils at the high pollution level (20 mg/kg), which was 14.2% higher than that at the middle pollution level (10 mg/kg). The degradation effect in the pepper soil was superior to that in the eggplant soil. Vegetable soil, either pepper soil or eggplant soil, which was polluted by various PAEs at different pollution gradients and then treated with PO-Yi fungus presented good bioremediation results. In the pepper and eggplant soil, 76.8% and 63.1% of the PAEs with a total volume of 60 mg/kg were degraded within 30 d respectively. PO-Yi, indigenous microorganisms, and the vegetables, i.e. pepper and eggplant had good synergistic effects on the degradation of compound PAEs in PAEpolluted pot soil. 展开更多
关键词 Fusarium oxysporum (PO-Yi) PHTHALATES SOIL BIODEGRADATION Pot experiment
下载PDF
上一页 1 下一页 到第
使用帮助 返回顶部