While lifestyle modifications are currently used as firstline treatment for subjects with gastroesophageal reflux disease (GERD), the pathogenetic role of lifestyle factors and consequently, the efficacy of lifestyle ...While lifestyle modifications are currently used as firstline treatment for subjects with gastroesophageal reflux disease (GERD), the pathogenetic role of lifestyle factors and consequently, the efficacy of lifestyle measures is controversial. Our aim was to systematically review the pathogenetic link between overweight/ obesity, dietary habits, physical activity and GERD, and the beneficial effect of specific recommended changes, by means of the available literature from the 1999 to the present. Obesity, in particular, abdominal obesity, plays a key role in determining GERD symptoms and complications through mechanical and metabolic effects. Controlled weight loss (by diet or surgery) is effective in improving GERD symptoms. No definitive data exist regarding the role of diet and, in particular, of specific foods or drinks, in influencing GERD clinical manifestations. Moderate physical activity seems to be beneficial for GERD, while vigorous activity may be dangerous in predisposed individuals. In conclusion, being obese/overweight and GERD-specific symptoms and endoscopic features are related, and weight loss significantly improves GERD clinical-endoscopic manifestations. The role of dietary behavior, mainly in terms of specific dietary components, remains controversial. Mild routine physical activity in association with diet modifications, i.e. a diet rich in fiber and low in fat, is advisable in preventing reflux symptoms.展开更多
OBJECTIVE： To evaluate the effect of a basic Chi- nese traditional diet （BTCD） in overweight patients on body mass index （BMI）, lean mass, sense of hun- ger, and eating behaviour. METHODS： A total of 694 enrolle...OBJECTIVE： To evaluate the effect of a basic Chi- nese traditional diet （BTCD） in overweight patients on body mass index （BMI）, lean mass, sense of hun- ger, and eating behaviour. METHODS： A total of 694 enrolled subjects （218 male and 476 female） were divided into two groups： group A undergoing a 1200-Kcal BTCD, and group B undergoing a 1200-Kcal standard western diet. RESULTS： From TO （before treatment） to T1 （6 weeks after treatment）, BMI was lowered in group A from （32.33±5.51） to （31.96±5.56） kg/m2, and in group B from （31.62±6.29） to （31.36±6.47） kglm2. After treatment, patients in group A lost more weight （0.37±0.52） kg than group B （0.26±0.79） kg （P=0.0044）. From TO to TI, the mean lean mass of group A decreased from （16.48±5.50） to （16.27± 5.45） kg. In group B, mean lean mass decreased from （16.93 ± 6.49） to （16.44 ± 6.29） kg. The differ- ence was significant （P=0.0078）. CONCLUSION： The two diets could lead to lowerBMI, improve lean mass as well as eating behaviour and sense of hunger. However, the BTCD was signif- icantly better than the western standard diet.展开更多
文摘While lifestyle modifications are currently used as firstline treatment for subjects with gastroesophageal reflux disease (GERD), the pathogenetic role of lifestyle factors and consequently, the efficacy of lifestyle measures is controversial. Our aim was to systematically review the pathogenetic link between overweight/ obesity, dietary habits, physical activity and GERD, and the beneficial effect of specific recommended changes, by means of the available literature from the 1999 to the present. Obesity, in particular, abdominal obesity, plays a key role in determining GERD symptoms and complications through mechanical and metabolic effects. Controlled weight loss (by diet or surgery) is effective in improving GERD symptoms. No definitive data exist regarding the role of diet and, in particular, of specific foods or drinks, in influencing GERD clinical manifestations. Moderate physical activity seems to be beneficial for GERD, while vigorous activity may be dangerous in predisposed individuals. In conclusion, being obese/overweight and GERD-specific symptoms and endoscopic features are related, and weight loss significantly improves GERD clinical-endoscopic manifestations. The role of dietary behavior, mainly in terms of specific dietary components, remains controversial. Mild routine physical activity in association with diet modifications, i.e. a diet rich in fiber and low in fat, is advisable in preventing reflux symptoms.
文摘OBJECTIVE： To evaluate the effect of a basic Chi- nese traditional diet （BTCD） in overweight patients on body mass index （BMI）, lean mass, sense of hun- ger, and eating behaviour. METHODS： A total of 694 enrolled subjects （218 male and 476 female） were divided into two groups： group A undergoing a 1200-Kcal BTCD, and group B undergoing a 1200-Kcal standard western diet. RESULTS： From TO （before treatment） to T1 （6 weeks after treatment）, BMI was lowered in group A from （32.33±5.51） to （31.96±5.56） kg/m2, and in group B from （31.62±6.29） to （31.36±6.47） kglm2. After treatment, patients in group A lost more weight （0.37±0.52） kg than group B （0.26±0.79） kg （P=0.0044）. From TO to TI, the mean lean mass of group A decreased from （16.48±5.50） to （16.27± 5.45） kg. In group B, mean lean mass decreased from （16.93 ± 6.49） to （16.44 ± 6.29） kg. The differ- ence was significant （P=0.0078）. CONCLUSION： The two diets could lead to lowerBMI, improve lean mass as well as eating behaviour and sense of hunger. However, the BTCD was signif- icantly better than the western standard diet.
