The multigene families undergo birth-and-death evolution and thus contribute to biological innovations. The APETALA2-1ike genes belong to the euAP2 group of the AP2 gene family. These genes are characterized by severa...The multigene families undergo birth-and-death evolution and thus contribute to biological innovations. The APETALA2-1ike genes belong to the euAP2 group of the AP2 gene family. These genes are characterized by several distinct motifs and exist in ferns, gymnosperms, and angiosperms. The phylogenetic analysis indicated that these genes have undergone the birth-and-death evolution. The five APETALA2-1ike genes in rice （Oryza sativa L.） display redundant but distinct expression patterns as demonstrated by RT-PCR and in situ hybridization. The potential functions of these genes were discussed on the basis of phylogenetic and expression pattern.展开更多
Objective： To determine the effect of dipeptide of glutamine and alanine on patients with severe traumatic brain injury. Methods： A total of 46 patients （31 males and 15 females, aged 7-68 years, （ 47 ± 9. 6...Objective： To determine the effect of dipeptide of glutamine and alanine on patients with severe traumatic brain injury. Methods： A total of 46 patients （31 males and 15 females, aged 7-68 years, （ 47 ± 9. 6 ） years on average ） with severe traumatic brain injury were randomized into two groups： Group G （n=23） and Group C （n =23）. The patients in Group G received nutritional remedy with the dipeptide of glutamine and alanine, whereas the patients in Group C received routine nutritional therapy only. GCS changes, the length of stay in the neurosurgical intensive care unit （NICU）, the mortality, the count of lymphocytes, related complications including lung infection and hemorrhage of alimentary tracts, etc, were examined and recorded. Results： The fatality rate and the length of stay in NICU in Group G was lower than these in Group C （P〈0.05）, but no obvious difference was found in GCS changes of the patients between the two groups （ P 〉 0.05 ）. The patients with lung infection and alimentary tract hemorrhage in Group G were less than those in Group C （P〈0.05）. The count of lymphocytes in Group G was more than that in Group C （P 〈0.05）, but no difference was found in other nutritional data. Conclusions： Dipeptide of glutamine and alanine can increase the resisting stress and anti-infection ability of patients with severe traumatic brain injury, which can also lower the mortality and shorten the NICU stay.展开更多
Objective： To detect the influencing factors for posttraumatic hydrocephalus in patients with severe traumatic brain injuries and provide theoretical reference for clinical treatment. Methods ： Retrospective study ...Objective： To detect the influencing factors for posttraumatic hydrocephalus in patients with severe traumatic brain injuries and provide theoretical reference for clinical treatment. Methods ： Retrospective study was made on 139 patients with severe traumatic brain injuries in our hospital. The patients were divided into two groups： hydrocephalus group and non-hydrocephalus group. Single factor analysis and multiple factor analysis were used to determine the related factors and hydrocephalus. Multiple factor analysis was conducted with logistic regression. Results： Posttraumatic hydrocephalus was found in 19.42% of patients. Age （ OR=1.050, 95% CI： 1.012-1. 090 ）, decompressive craniectomy （ OR =4.312, 95 %CI ： 1. 127-16.503 ）, subarachnoid hemorrhage （ OR = 43.421, 95 % CI ： 7. 835-240. 652 ） and continuous lumbar drainage of cerebrospinal fluid （ OR =0.045, 95%CI： 0. 011-0. 175） were screened out from nine factors as the influencing factors for posttraumatic hydrocephalus. Conclusions ： Risk factors for PTH are as follows： age, deeompressive eranieetomy and subaraehnoid hemorrhage （SAH）. Continuous lumbar drainage of eerebrospinal fluid can greatly reduce posttraumatic hydrocephalus.展开更多
基金the National Natural Science Foundation of China (No. 30600034 and 30621001)Chinese Acad-emy of Sciences (No. CXTD-S2005-2).
文摘The multigene families undergo birth-and-death evolution and thus contribute to biological innovations. The APETALA2-1ike genes belong to the euAP2 group of the AP2 gene family. These genes are characterized by several distinct motifs and exist in ferns, gymnosperms, and angiosperms. The phylogenetic analysis indicated that these genes have undergone the birth-and-death evolution. The five APETALA2-1ike genes in rice （Oryza sativa L.） display redundant but distinct expression patterns as demonstrated by RT-PCR and in situ hybridization. The potential functions of these genes were discussed on the basis of phylogenetic and expression pattern.
文摘Objective： To determine the effect of dipeptide of glutamine and alanine on patients with severe traumatic brain injury. Methods： A total of 46 patients （31 males and 15 females, aged 7-68 years, （ 47 ± 9. 6 ） years on average ） with severe traumatic brain injury were randomized into two groups： Group G （n=23） and Group C （n =23）. The patients in Group G received nutritional remedy with the dipeptide of glutamine and alanine, whereas the patients in Group C received routine nutritional therapy only. GCS changes, the length of stay in the neurosurgical intensive care unit （NICU）, the mortality, the count of lymphocytes, related complications including lung infection and hemorrhage of alimentary tracts, etc, were examined and recorded. Results： The fatality rate and the length of stay in NICU in Group G was lower than these in Group C （P〈0.05）, but no obvious difference was found in GCS changes of the patients between the two groups （ P 〉 0.05 ）. The patients with lung infection and alimentary tract hemorrhage in Group G were less than those in Group C （P〈0.05）. The count of lymphocytes in Group G was more than that in Group C （P 〈0.05）, but no difference was found in other nutritional data. Conclusions： Dipeptide of glutamine and alanine can increase the resisting stress and anti-infection ability of patients with severe traumatic brain injury, which can also lower the mortality and shorten the NICU stay.
文摘Objective： To detect the influencing factors for posttraumatic hydrocephalus in patients with severe traumatic brain injuries and provide theoretical reference for clinical treatment. Methods ： Retrospective study was made on 139 patients with severe traumatic brain injuries in our hospital. The patients were divided into two groups： hydrocephalus group and non-hydrocephalus group. Single factor analysis and multiple factor analysis were used to determine the related factors and hydrocephalus. Multiple factor analysis was conducted with logistic regression. Results： Posttraumatic hydrocephalus was found in 19.42% of patients. Age （ OR=1.050, 95% CI： 1.012-1. 090 ）, decompressive craniectomy （ OR =4.312, 95 %CI ： 1. 127-16.503 ）, subarachnoid hemorrhage （ OR = 43.421, 95 % CI ： 7. 835-240. 652 ） and continuous lumbar drainage of cerebrospinal fluid （ OR =0.045, 95%CI： 0. 011-0. 175） were screened out from nine factors as the influencing factors for posttraumatic hydrocephalus. Conclusions ： Risk factors for PTH are as follows： age, deeompressive eranieetomy and subaraehnoid hemorrhage （SAH）. Continuous lumbar drainage of eerebrospinal fluid can greatly reduce posttraumatic hydrocephalus.
