Six indigenous folk medicinal plants growing wild in the area of Tabuk, Saudi Arabia which were selected for the study of their phytochemistry as well as their biological activities as antitumor and antifolate agents....Six indigenous folk medicinal plants growing wild in the area of Tabuk, Saudi Arabia which were selected for the study of their phytochemistry as well as their biological activities as antitumor and antifolate agents. Antitumor activities of methanol extracts of the six plants were measured in vitro using three human tumor cell lines （breast, lung and CNS cancers） while antifolate activities were assessed using commercial dihyrofolate reductase obtained from Sigma Co. Among the six plant extracts tested, the most remarkable were those of Caralluma sinaica and Fagonia tenuifolia. Caralluma extract showed strong antitumor activity （low GIso） against the three human tumor cell lines. Fagonia extract, on the other hand, was quite inhibitory to the growth of CNS cancer and breast cancer cell lines but much less so against lung cancer cells. Extracts of both Sonchus oleraceus and Caralluma sinaica were strongly inhibitory to DHFR. These results suggest that the mechanism of anticancer activity of Caralluma plant is through DHFR inhibition but that of Fagonia may follow a different path.展开更多
This paper presents some thoughts about the Maison du Bresil. The objective is to research this temporary residency for researchers through the meanings that characterize it as a Brazilian territory in Paris and throu...This paper presents some thoughts about the Maison du Bresil. The objective is to research this temporary residency for researchers through the meanings that characterize it as a Brazilian territory in Paris and through the very belonging to the category elite as a peculiarity of its residents. The author wish to analyze the international circulation of students and researchers that live there and have an educational experience of multiple dimensions as experiences of deterritorialization of identities and its consequences in a housing space which is at the same time in public and private. Based on documental analysis and ethnographic fieldwork, the paper presents some aspects of the history and the everyday life of the Maison du Bresil and Paris＇ Cite Internationale Universitaire. Also, it intends to show how the meanings of Brazilianness are used as support for the identity crisis lived by the members of a supposed Brazilian elite in Paris, as it analyzes the particularities of the mediations established by the residents of the Maison du Bresil, in the formation and international insertion of some researchers.展开更多
The aim of this study is to observe the prospect of kingship in Nepal. It presents an analysis of the people＇s perspective on dismissed monarchy and challenges faced by Nepal. There was little voice on Nepali monarch...The aim of this study is to observe the prospect of kingship in Nepal. It presents an analysis of the people＇s perspective on dismissed monarchy and challenges faced by Nepal. There was little voice on Nepali monarchy system, yet many individuals and researcher expressed the need for monarchy to build nation and keep its culture, tradition, and nation unity. To promote the democratic system, political parties should practice democratic norms and respect rules of law in real life rather than just in talk. For the express of people voice and envision prosperous Nepal, this paper attempts to contribute to the need of monarchy back in Nepal far its savereignty and unity. The paper gives a historical overview of kingship in Nepal and discusses incompetent political parties and the importance of monarchy in Nepal. It identifies that to unite the Nepal and Nepali and give the nation social cultural identity, and it needs any form of monarchy in Nepal. The past and present, despite of political systems, social movement, and practice seen from the political parties were failed several times to fulfill people＇s mandate, such as holding election, writing constitution. The fields discussed in the paper include apathetic attitude of the political parties toward establishing peace and stability in Nepal.展开更多
文摘Six indigenous folk medicinal plants growing wild in the area of Tabuk, Saudi Arabia which were selected for the study of their phytochemistry as well as their biological activities as antitumor and antifolate agents. Antitumor activities of methanol extracts of the six plants were measured in vitro using three human tumor cell lines （breast, lung and CNS cancers） while antifolate activities were assessed using commercial dihyrofolate reductase obtained from Sigma Co. Among the six plant extracts tested, the most remarkable were those of Caralluma sinaica and Fagonia tenuifolia. Caralluma extract showed strong antitumor activity （low GIso） against the three human tumor cell lines. Fagonia extract, on the other hand, was quite inhibitory to the growth of CNS cancer and breast cancer cell lines but much less so against lung cancer cells. Extracts of both Sonchus oleraceus and Caralluma sinaica were strongly inhibitory to DHFR. These results suggest that the mechanism of anticancer activity of Caralluma plant is through DHFR inhibition but that of Fagonia may follow a different path.
文摘This paper presents some thoughts about the Maison du Bresil. The objective is to research this temporary residency for researchers through the meanings that characterize it as a Brazilian territory in Paris and through the very belonging to the category elite as a peculiarity of its residents. The author wish to analyze the international circulation of students and researchers that live there and have an educational experience of multiple dimensions as experiences of deterritorialization of identities and its consequences in a housing space which is at the same time in public and private. Based on documental analysis and ethnographic fieldwork, the paper presents some aspects of the history and the everyday life of the Maison du Bresil and Paris＇ Cite Internationale Universitaire. Also, it intends to show how the meanings of Brazilianness are used as support for the identity crisis lived by the members of a supposed Brazilian elite in Paris, as it analyzes the particularities of the mediations established by the residents of the Maison du Bresil, in the formation and international insertion of some researchers.
文摘The aim of this study is to observe the prospect of kingship in Nepal. It presents an analysis of the people＇s perspective on dismissed monarchy and challenges faced by Nepal. There was little voice on Nepali monarchy system, yet many individuals and researcher expressed the need for monarchy to build nation and keep its culture, tradition, and nation unity. To promote the democratic system, political parties should practice democratic norms and respect rules of law in real life rather than just in talk. For the express of people voice and envision prosperous Nepal, this paper attempts to contribute to the need of monarchy back in Nepal far its savereignty and unity. The paper gives a historical overview of kingship in Nepal and discusses incompetent political parties and the importance of monarchy in Nepal. It identifies that to unite the Nepal and Nepali and give the nation social cultural identity, and it needs any form of monarchy in Nepal. The past and present, despite of political systems, social movement, and practice seen from the political parties were failed several times to fulfill people＇s mandate, such as holding election, writing constitution. The fields discussed in the paper include apathetic attitude of the political parties toward establishing peace and stability in Nepal.
