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针刺“百会”透“曲鬓”穴拮抗急性脑出血大鼠炎性损伤的机制研究 被引量:27
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作者 陈秋欣 邹伟 +7 位作者 孙晓伟 于学平 戴晓红 牛明明 滕伟 包宇 于薇薇 马慧慧 《针刺研究》 CAS CSCD 北大核心 2016年第5期410-416,共7页
目的:探讨针刺"百会"透"曲鬓"穴拮抗急性脑出血大鼠炎性损伤的作用机制。方法:54只Wistar大鼠随机分为假手术组、模型组及针刺组,每组按造模后1、3、7d分为3个亚组,每组6只。采用自体血注入法建立脑出血大鼠模型。... 目的:探讨针刺"百会"透"曲鬓"穴拮抗急性脑出血大鼠炎性损伤的作用机制。方法:54只Wistar大鼠随机分为假手术组、模型组及针刺组,每组按造模后1、3、7d分为3个亚组,每组6只。采用自体血注入法建立脑出血大鼠模型。针刺组取"百会"透患侧"曲鬓"进行治疗,24h治疗1次。采用Longa评分法及肢体对称实验评分法对脑出血后大鼠神经功能进行评估,采用免疫组化法检测脑出血组织Toll样受体4(TLR-4)、肿瘤坏死因子(TNF-α)、白介素(IL)-6的阳性表达。结果:模型组大鼠脑出血损伤后出现不同程度的神经功能缺损症状表现,术后3d大鼠神经功能缺损最重;针刺后神经功能缺损明显减轻,针刺组各时间点与模型组比较差异有统计学意义(P<0.01)。在各时间点假手术组大鼠脑组织可见少量TNF-α、TLR-4、IL-6阳性表达;模型组在各时间点TNF-α、TLR-4、IL-6阳性表达均高于假手术组(P<0.01);针刺组在各时间点与模型组比较,TNF-α、TLR-4、IL-6阳性表达明显下调(P<0.01)。TLR-4与IL-6表达呈正相关,TLR-4与TNF-α表达呈正相关。结论:针刺"百会"透"曲鬓"穴可以抑制TLR-4蛋白的表达,降低血肿组织中炎性因子TNF-α、IL-6的含量,减轻脑出血后炎性损伤,改善大鼠神经功能缺损表现。 展开更多
关键词 () 脑出血 肿瘤坏死因子-α 白介素-6 TOLL样受体4
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Effect of complex reinforcing-reducing manipulation on lower limb motion and balance disorder in patients with subacute combined degeneration of the spinal cord 被引量:2
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作者 张朝红 李旗 《Journal of Acupuncture and Tuina Science》 CSCD 2015年第3期189-193,共5页
Objective:To observe the effect of complex reinforcing [Shao Shan Huo (Mountain-burning Fire)] and reducing [Tou Tian Liang (Heaven-penetrating Cooling)] manipulations on motion and balance of the lower limbs in ... Objective:To observe the effect of complex reinforcing [Shao Shan Huo (Mountain-burning Fire)] and reducing [Tou Tian Liang (Heaven-penetrating Cooling)] manipulations on motion and balance of the lower limbs in patients with subacute combined degeneration of the spinal cord (SCD). Methods:A total of 100 SCD cases were randomly allocated into an observation group and a control group by their visit sequence, 50 cases in each group. On the basis of Western medical treatment, cases in the observation group were also treated with acupuncture therapy plus complex reinforcing-reducing manipulation; whereas cases in the control group were only treated with the same Western medical treatment as those in the observation group. Before and 2 months after treatment, kinematic parameters including muscle force, muscle tone and range of motion of the hip and knee joints were measured. In addition, balancing parameters including the path length of center of pressure (COP), peripheral area, COP path length per unit area and rectangular area were also measured before and after treatment. Results:After treatment, there were statistical intra-group differences in COP path length, peripheral area, COP path length per unit area, left-right offset, rectangular area, coefficient of stability and coefficient of weight distribution (P〈0.01). There were statistical inter-group differences in muscle force, muscle tone and range of motion of hip and knee joints (P〈0.01). The total effective rate was 83.3% in the observation group, versus 60.0% in the control group, showing a statistical difference (P〈0.05). Conclusion:Complex reinforcing-reducing manipulations can improve the lower limb motion and balance in SCD patients. 展开更多
关键词 Acupuncture Therapy Method of Reinforcing-reducing Vitamin B12 Deficiency
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Effect of complex reinforcing-reducing manipulations on hip and knee flexion and extension angles after surgery of gluteus maximus contracture
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作者 郑德松 赵岩 +2 位作者 李旗 田福玲 韩丑萍 《Journal of Acupuncture and Tuina Science》 CSCD 2015年第1期58-62,共5页
Objective: To observe the effect of complex reinforcing-reducing manipulations of acupuncture on flexion and extension angles of hip and knee in patients after surgical treatment of gluteus maximus contracture. 〈br... Objective: To observe the effect of complex reinforcing-reducing manipulations of acupuncture on flexion and extension angles of hip and knee in patients after surgical treatment of gluteus maximus contracture. 〈br〉 Methods: A total of 66 cases following surgery of gluteus maximus contracture were randomly allocated into an observation group and a control group by the random digits table, 33 in each group. In addition to basic treatment, cases in the observation group were treated with reducing manipulation [Tou T ian Liang (Heaven-penetrating Cooling)] on Zhibian (BL 54), Huantiao (GB 30) and Juliao (GB 29) on the affected side and reinforcing manipulation [Shao Shan Huo (Mountain-burning Fire)] on Biguan (ST 31), Futu (ST 32), Zusanli (ST 36), Fenglong (ST 40), Xuehai (SP 10), Diji (SP 8) and Yanglingquan (GB 34). Patients in the control group only received the same basic treatment as the observation group. The treatment was done once a day, 30 d for a course and a 1-week interval between two courses. Then the flexion and extension angles of hip and knee were evaluated using the Lokomat full automatic robot gait evaluation system after 3 courses of treatment. 〈br〉 Results:There were intra-group statistical differences in hip flexion angle on foot followed (HFA-FF), the maximum of hip flexion angle (MAX-HFA), the maximum of hip extension angle (MAX-HEA), knee flexion angle on foot followed (KFA-FF), the maximum of knee flexion angle on stance phase (MAX-KFA-TP) and the maximum of knee flexion angle on swing phase (MAX-KFA-WP) in the observation group and in HFA-FF, MAX-HEA and KFA-FF in the control group (P&lt;0.05). There were between-group statistical differences in HFA-FF, MAX-HFA, MAX-HEA, KFA-FF and MAX-KFA-TP (P&lt;0.05). 〈br〉 Conclusion: The complex reinforcing-reducing manipulations of acupuncture can effectively improve the hip/knee functions following surgery of gluteus maximus contracture. 展开更多
关键词 Acupuncture Therapy Method of Reinforcing-reducing
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