Drug withdrawal with acupuncture appeared in 1970 s, which is one of the major achievements in modern medicine. The paper reviews the formation and development of acupuncture in drug withdrawal, analyzes its advantage...Drug withdrawal with acupuncture appeared in 1970 s, which is one of the major achievements in modern medicine. The paper reviews the formation and development of acupuncture in drug withdrawal, analyzes its advantages and mechanisms as well as the questions encountered in drug withdrawal. Additionally, some feasible suggestions are provided for the further development of acupuncture in drug withdrawal.展开更多
Objective： To observe the effects of electroacupuncture on withdrawal anxiety in heroin-dependent patients. Methods： Sixty heroin-withdrawal subjects with negative urine morphine were digitally randomized into two g...Objective： To observe the effects of electroacupuncture on withdrawal anxiety in heroin-dependent patients. Methods： Sixty heroin-withdrawal subjects with negative urine morphine were digitally randomized into two groups： acupuncture group in which 30 cases were treated by electroacupuncture and control group in which 30 cases were given no treatment. The patients were assessed by Hamilton anxiety scale before treatment and one week, two weeks and three weeks after treatment. Results： After treatment, the anxiety symptoms of heroin-dependent patients were improved more significantly in the acupuncture group than in the control group （P〈0.01）. Conclusion： Electroacupuncture has good effects on anxiety symptoms and emotions of heroin-dependent patients.展开更多
Objective： To investigate the intervention effect of electroacupuncture on postwithdrawal anxiety and depression of those with heroin dependence. Method： One hundred and twenty heroin dependence cases were randomly ...Objective： To investigate the intervention effect of electroacupuncture on postwithdrawal anxiety and depression of those with heroin dependence. Method： One hundred and twenty heroin dependence cases were randomly allocated into 4 groups, including acupuncture group 1 using Jiaji （Ex-B 2） points and Shenshu （BL 23）, acupuncture group 2 using points in the four limbs, simulation and control groups. Then the SAS and SDS changes were observed before the treatment and 4th, 8th and 10th week after. Result： At the 4th, 8th and 10th week, the SAS and SDS scores in acupuncture group 1 and 2 showed significant differences with the control group （P〈0.01, P〈0.05）. There were significant differences between SAS changes in acupuncture group 1 and 2 but there was no significant difference in SDS changes. Conclusion： Electroacupuncture can improve the post-withdrawal anxiety and depression in heroin addicts. Jiaji （Ex-B 2） points showed significantly better effects in improving anxiety than points in four limbs but no significant difference in improving depression.展开更多
Objective To evaluate the clinical efficacy of acupuncture on depression in nicotine withdrawal. Methods Seventy-four cases of depression after nicotine withdrawal were selected as the subjects in observation and they...Objective To evaluate the clinical efficacy of acupuncture on depression in nicotine withdrawal. Methods Seventy-four cases of depression after nicotine withdrawal were selected as the subjects in observation and they were randomized into an acupuncture group （38 cases） and a western medicine group （36 cases）. In the acupuncture group, acupuncture was applied to Bǎihuì （百会 GV 20）, Yìntáng （印堂 EX-HN 3）, Sānyīnjiāo （三阴交 SP 6）, Tàichōng （太冲 LR 3）, Nèiguān （内关 PC 6） and Hégǔ （合谷 LI 4）. In the western medicine group, Fluoxetine was prescribed for oral administration, once per day. Hamilton Depression Scale （HAMD） was adopted for the evaluation before and after treatment separately and the changes in HAMD score as well as the efficacy were compared before and after treatment. Results HAMD score in either acupuncture group or western medicine group was improved significantly as compared with that before treatment （all P0.05）. The effective rate was 89.5% （34/38） in the acupuncture group and was 91.7% （33/36） in the western medicine group. There was no statistically significant difference between the two groups （all P0.05）. Conclusion The efficacy of acupuncture is similar to that of Fluoxetine in the treatment of depression in nicotine withdrawal.展开更多
Objective： To observe the effect of electro-acupuncture on the relapse to heroin-seeking induced by heroin-related cues after withdrawal from heroin self-administration in rats. Methods： Sixty male Wistar rats were ...Objective： To observe the effect of electro-acupuncture on the relapse to heroin-seeking induced by heroin-related cues after withdrawal from heroin self-administration in rats. Methods： Sixty male Wistar rats were randomized into physiological saline group, withdrawal group A, withdrawal group B, electro-acupuncture （EA） treatment group A and EA treatment group B, with 12 rats in each group. The rats were trained by nose-poke response to self administer heroin （50μg/kg/per infusion） or saline with one daily 4-h session for 14 consecutive days, the session ended after 25 infusions were earned or 4 hours had passed, the reinforcement schedule was a progressive ratio. Then rats in withdrawal group A and withdrawal group B were withdrawn from heroin for 1 week and 2 weeks respectively, and then they were reintroduced to their training chambers for 4-h relapse testing which was induced by heroin-related environmental cues; And rats in EA treatment group A and EA treatment group B were also withdrawn from heroin for 1 week and 2 weeks respectively, during which they were given EA treatment for 20 min daily, then they received relapse testing; In the meantime, rats in saline group were trained with saline instead of heroin for 14 days as control, after 7 days of withdrawal from saline, they received relapse testing. Results： Following 7-8 days of drug training, the rats began to establish the stable intravenous heroin self-administration behavior; For the stable heroin self-administrating rats that received EA treatment, when they were reintroduced to their training chambers, their heroin-seeking behaviors were obviously inhibited, and this inhibitory effect related to the cumulativeness of EA stimulation. Conclusion： The results suggested that EA could prevent relapse to heroin-seeking to a certain extent.展开更多
文摘Drug withdrawal with acupuncture appeared in 1970 s, which is one of the major achievements in modern medicine. The paper reviews the formation and development of acupuncture in drug withdrawal, analyzes its advantages and mechanisms as well as the questions encountered in drug withdrawal. Additionally, some feasible suggestions are provided for the further development of acupuncture in drug withdrawal.
基金Shanghai Municipal Education Commission(CZ0523)Shanghai Leading Academic Discipline Project(T0302)
文摘Objective： To observe the effects of electroacupuncture on withdrawal anxiety in heroin-dependent patients. Methods： Sixty heroin-withdrawal subjects with negative urine morphine were digitally randomized into two groups： acupuncture group in which 30 cases were treated by electroacupuncture and control group in which 30 cases were given no treatment. The patients were assessed by Hamilton anxiety scale before treatment and one week, two weeks and three weeks after treatment. Results： After treatment, the anxiety symptoms of heroin-dependent patients were improved more significantly in the acupuncture group than in the control group （P〈0.01）. Conclusion： Electroacupuncture has good effects on anxiety symptoms and emotions of heroin-dependent patients.
基金National Natural Science Foundation of China(30271637)
文摘Objective： To investigate the intervention effect of electroacupuncture on postwithdrawal anxiety and depression of those with heroin dependence. Method： One hundred and twenty heroin dependence cases were randomly allocated into 4 groups, including acupuncture group 1 using Jiaji （Ex-B 2） points and Shenshu （BL 23）, acupuncture group 2 using points in the four limbs, simulation and control groups. Then the SAS and SDS changes were observed before the treatment and 4th, 8th and 10th week after. Result： At the 4th, 8th and 10th week, the SAS and SDS scores in acupuncture group 1 and 2 showed significant differences with the control group （P〈0.01, P〈0.05）. There were significant differences between SAS changes in acupuncture group 1 and 2 but there was no significant difference in SDS changes. Conclusion： Electroacupuncture can improve the post-withdrawal anxiety and depression in heroin addicts. Jiaji （Ex-B 2） points showed significantly better effects in improving anxiety than points in four limbs but no significant difference in improving depression.
基金Supported by Scienfic and Research Project of the Health Bureau, Foshan, Guangdong: 2011497
文摘Objective To evaluate the clinical efficacy of acupuncture on depression in nicotine withdrawal. Methods Seventy-four cases of depression after nicotine withdrawal were selected as the subjects in observation and they were randomized into an acupuncture group （38 cases） and a western medicine group （36 cases）. In the acupuncture group, acupuncture was applied to Bǎihuì （百会 GV 20）, Yìntáng （印堂 EX-HN 3）, Sānyīnjiāo （三阴交 SP 6）, Tàichōng （太冲 LR 3）, Nèiguān （内关 PC 6） and Hégǔ （合谷 LI 4）. In the western medicine group, Fluoxetine was prescribed for oral administration, once per day. Hamilton Depression Scale （HAMD） was adopted for the evaluation before and after treatment separately and the changes in HAMD score as well as the efficacy were compared before and after treatment. Results HAMD score in either acupuncture group or western medicine group was improved significantly as compared with that before treatment （all P0.05）. The effective rate was 89.5% （34/38） in the acupuncture group and was 91.7% （33/36） in the western medicine group. There was no statistically significant difference between the two groups （all P0.05）. Conclusion The efficacy of acupuncture is similar to that of Fluoxetine in the treatment of depression in nicotine withdrawal.
基金Supported by the National Nature Science Foundation （30271637） and the State Administration of TCM （02-03LQ05）
文摘Objective： To observe the effect of electro-acupuncture on the relapse to heroin-seeking induced by heroin-related cues after withdrawal from heroin self-administration in rats. Methods： Sixty male Wistar rats were randomized into physiological saline group, withdrawal group A, withdrawal group B, electro-acupuncture （EA） treatment group A and EA treatment group B, with 12 rats in each group. The rats were trained by nose-poke response to self administer heroin （50μg/kg/per infusion） or saline with one daily 4-h session for 14 consecutive days, the session ended after 25 infusions were earned or 4 hours had passed, the reinforcement schedule was a progressive ratio. Then rats in withdrawal group A and withdrawal group B were withdrawn from heroin for 1 week and 2 weeks respectively, and then they were reintroduced to their training chambers for 4-h relapse testing which was induced by heroin-related environmental cues; And rats in EA treatment group A and EA treatment group B were also withdrawn from heroin for 1 week and 2 weeks respectively, during which they were given EA treatment for 20 min daily, then they received relapse testing; In the meantime, rats in saline group were trained with saline instead of heroin for 14 days as control, after 7 days of withdrawal from saline, they received relapse testing. Results： Following 7-8 days of drug training, the rats began to establish the stable intravenous heroin self-administration behavior; For the stable heroin self-administrating rats that received EA treatment, when they were reintroduced to their training chambers, their heroin-seeking behaviors were obviously inhibited, and this inhibitory effect related to the cumulativeness of EA stimulation. Conclusion： The results suggested that EA could prevent relapse to heroin-seeking to a certain extent.
