针刺刺法之四时宜忌探讨

基于"天人合一"的观点,《素问》提出了因时制宜的治疗原则,并以此指导针刺的治疗。人体在四时气候变化的影响下,会产生不同的适应性变化,而针刺顺应四时,也有相应的刺法,各有不同。

SUMMARY OF CLINICAL STUDY ON ACUPUNCTURE COMBINED WITH EPIDURAL ANESTHESIA FOR CHOLECYSTECTOMY

Objective: TO study clinical effect and anesthetic method of acupuncture anesthesia combined with epidural administration of small dose of anesthetic for cholecystectomy. Methods: A total of 194 cases of cholecystectomy patients were randomly divided into acupuncture combined with epidural anesthesia group (group A, n = 66), acupoint-skin electrical stimulation combined with epidural anesthesia group (group B, n = 63) and simple epidural anesthesia group (group C, n=65). Observations were conducted using single-bland method. Bilateral Neiguan (PC 6) and Zusanli (ST 36) were punctured and stimulated electrically in group A and only stimulated electrically via cutaneous electrodes in group B. Epidural anesthetic used was 1.5% Lidocaine and the anesthetic level was controlled to reach T4-11 . Results: The class-I (excellent) rates of group A, B and C were 75.76%, 60.32% and 13.85% respectively, showing significant differences between group A and C and group B and C (P <0.001). The initial dose, doses of every hour and every case of group A and B were lower than those of group C. The dose of every hour of group C was 36.23% and 3. 75% higher then group A and B respectively (P < 0. 001), suggesting that acupuncture or acupoint-skin electrical stimulation could strengthen anesthetic effect and reduce the dose of epidural anesthetic. During operation, indexes of the life signs as HR, MAP, RR, TV, MV, SpO2 and ECG kept basically stable and all patients in group A passed surgical operation safely. Conclusion: Acupuncture or acupoint-skin electrical stimulation combined with epidural anesthesia can be used as one of the anesthetic methods for cholecystectomy.

Treatment of Chronic Pelvic Inflammation with Acupuncture and TDP Irradiation—A Report of 23 Cases

With electro-acupuncture, red-hot needling and TDP irradiation, we have successfully treated 23 cases of chronic pelvic inflammation. A report follows.

Clinical Experience in Multiple Needling Therapy

The multiple needling therapy refers to the techniques used in acupuncture treatment with multineedles in multi-directions. But, it does not mean that more insertions with more needles would bring about better therapeutic effects.

TREATMENT OF 100 CASES OF ACUTE URTICARIA WITH ELECTROACUPUNCTURE

Objective: To observe the therapeutic effect of clinical treatment of acute urticaria chiefly by electroacupuncture (EA). Methods: A total of 180 outpatients with acute urticaria were randomized into treatment group and control group. 100 cases in the treatment group were treated with EA at Quchi (曲池 LI 11) and Xuehai (血海 SP 10) as the main points which were supplemented with Dazhui (大椎 GV 14), Fengchi (风池 GB 20), Geshu (膈俞 BL 17), Pishu (脾俞 BL 20), etc. 80 cases in the control group were managed by chlorpheniramine maleate and Vitamin C. Results: After 3 days’ treatment, of the 100 and 80 cases in treatment and control groups, 79 and 53 were cured, 10 and 6 markedly effective, 5 and 8 effective, and 6 and 13 failed, with the effective rates being 94.00% and 83.75% respectively. The therapeutic effect of electroacupunture was significantly superior to that of medication(P<0.05). Conclusion: The method of electroacupuncture at Quchi (曲池 LI 11), Xuehai (血海 SP 10),etc. was a more effective therapy for acute urticaria.

EFFECT OF ELECTROACUPUNCTURE OF DUMAI-ACUPOINTS ON CEREBRAL NO AND BLOOD ENDOTHELIN CONTENTS IN RATS WITH ACUTE CEREBRAL ISCHEMIA

Thirty Wistar rats were randomly and evenly divided into control group, cerebral ischemia group and ischemia + electroacupuncture (EA) group. The bilateral common carotid arteries were occluded to induce acute cerebral ischemia. Nitric oxide (NO) and endothelin (ET)contents in the cerebral tissues and blood were measured under normal condition, immediately after ischemia and following EA. Results showed that after acute cerebral ischemia NO and ET contents in the cerebral tissues increased significantly (P<0.01) while serum ET increased and serum NO lowered obviously (P<0.05). Following EA of Baihui (GV 20) and Dazhui (GV 14), both NO and ET in cerebral tissues and serum turned to normal basically. It showed that EA could protect the cerebral tissues from injury induced by ischemia, NO and ET might participate in the modulation process of EA.

EFFECT OF ELECTROACUPUNCTURE ON RED BLOOD CELL IMMUNE AND T-CELL SUBGROUP IN THE RAT

In the present study, the effect of electroacupuncture (EA) on immune system was observed in the rat by using micro- whole blood direct immunofluorescence staining assay to detect changes of the peripheral blood T lymphocyte subgroup and employing red blood cell (RBC) C 3b receptor- yeast rosette test and red blood cell-IC rosette test to analyze erythrocytic immune function. Results showed that after EA of “Zusanli" (ST 36), CD+ 4, RBC-C 3bRR and RBC-ICR in the peripheral blood of the normal rats increased significantly while CD+ 8 had no any considerable changes and a positive correlation between CD+ 4 and RBC-C 3bRR was found. In immunosuppression model rats, the values of CD+ 4 and RBC-C 3bRR were obviously lower than those of the normal control group while CD+ 8 had no any striking changes; but after EA treatment, there were no evident differences between EA group and normal control group in the above-mentioned indexes. There were also no any significant differences between non-acupoint group and normal control group in those indexes. Results suggest that EA of “Zusanli" (ST 36) can raise T cell immune function and RBC adhesion function in both normal rats and immunosuppression model rats, both of which present a positive correlation.

OBSERVATION ON THE THERAPEUTIC EFFECT OF ENCLOSING NEEDLING UNDER CT ORIENTATION FOR TREATMENT OF ISCHEMIC CEREBRAL STROKE AND ITS INFLUENCE ON PLASMA NO

In the present paper, 61 cases of ischemic cerebral apoplexy were randomly divided into enclosing needling group (n=31) and scalpacupuncture group (n=30). After 30 sessions of treatment, there was a significant difference between the two groups in the therapeutic effect (P<0.05), indicating enclosing needling being superior to scalpacupuncture. Both enclosing needling and scalpacupuncture could lower plasma NO content while the former was more apparent in lowering plasma NO level.

Therapeutic efficacy of swallowing neuromuscular electrical stimulation combined with acupuncture for post-stroke dysphagia

Objective To seek a better therapy for treating post-stroke dysphagia. Methods Patients with stroke and swallowing disorders were randomly divided into ordinary acupuncture group （group A, 58 cases） and swallowing neuromuscular electrical stimulation combined with acupuncture group （group B, 62 cases）. Two-group patients were given the same basic internal medical treatment. In addition, group A was given normal acupuncture treatment with the choice of local points： Junjin （金津 EX-HN 12）, Yuye（玉液 EX-HN 23）, Fengchi （风池 GB 20）, Yifeng （翳风 TE 17）, Lianquan （廉泉 CV 23）, Wangu （完骨 GB 12）. Group B was given swallowing neuromuscular electrical stimulation combined with acupuncture： GB 20, Fengfu （风夜 GV 16）, TE 17, Yiming （翳明 EX-HN 14）, Yamen （哑门 GV 15）, Tianrong（天容 SI 17）, Tianchuang （天窗 SI 16）, CV 23, the uniform reinforcing-reducing manipulation was used; EX- HN 12, EX-HN 13, the piercing and blood-letting method （1-2 mL blood） was used; at the same time, the swallowing neuromuscular electrical stimulation therapy device was used to electrically stimulate the nerves and muscles in the throat and neck at specific output pulse current （50-100 Hz）. Treatment was made twice a day, 30 minutes each time. Two weeks after the treatment, the patients were assessed in symptoms improvement and clinical efficacy. Results The total effective rate in group B was 91.4% and 75.8% in group A; in the total efficiency comparison in both groups, χ^2=5.232, P〈0.05. The difference in improvement of symptoms with post-stroke dysphagia treated with above mentioned combination treatment was statistically significant between both groups （P〈0.05）. Conclusion The above mentioned swallowing neuromuscular electrical stimulation combined with acupuncture treatment has a better clinical effect when compared with ordinary acupuncture.

Modern and ancient knowledge about “deqi ” and analysis on the researches in recent 10 years

Objective With the development of science of acupuncture and moxibustion, people have, in the knowledge of ＂deqi＂, developed from subjective level to the quantitative level, and discovered many factors influencing the ＂deqi＂ of acupuncture. In this report, the relationship between ＂deqi＂ and these factors was explored in terms of different acupuncture methods and quantity and depth of stimulus. Methods Ancient literature about ＂deqi＂, as well as related literature for clinical and basic research on ＂deqi＂ in recent 10 years were systematically collected. Results （1） Cerebral functional imaging technology and the scale of ＂deqi＂ were the most common quantitative indexes for ＂deqi＂ in recent 10 years. （2） There were many factors influencing ＂deqi＂ in acupuncture, which involved personal physiological status, nature of disease, anatomical features under the acupoint, different acupuncture methods, quantity and depth of stimulus, etc. Different acupuncture methods, quantity and depth of stimulus would bring different influences on and mechanisms of ＂deqi＂. Conclusion （1） ＂Deqi＂ is not equal to needling sensation; （2） recessive needling sensation should be re-recognized; （3） the sensation of doctor should be paid attention; （4） The meaning of ＂deqi＂ should be re-defined and re-understood.

Clinical efficacy of opposing needling in the treatment of migraine with the symptom of ascendant hyperactivity of liver yang and its effect on NO level in plasma of patients

Objective To observe the clinical efficacy of opposing needling for the treatment of migraine with the symptom of hyperactivity of liver yang type and its effect on NO level in plasma of patients. Methods Atotal of 60 migraine patients with the symptom of hyperactivity of liver yang who met the inclusive criteria were randomly divided into a opposing needling group （group A） and a routine acupuncture group （group B） by using SPSS 15.0 software according to the registration order with 30 patients in each group. Patients in group A were treated with opposing needling. Taich6ng （太冲 LR 3）, Zhongzhu （中渚 TE 3）, ZOlfnqi （足临泣 GB 41） and QiOxu （丘墟 GB 40） in the uninjured side were selected. After deqi, reducing method was used. Then Taixi （太溪 KI 3） in the uninjured side was selected. After deqi, rein forcing method was used. Needles were retained for 30 rain. Patients in group B were treated with routine acupuncture. Local Ash point, Sishncong （ 四神聪EX-HN1）, Yifeng （翳风 TE 17）, Fengchi （风池 GB 20）, Sizhukong （丝竹空 TE 23）, Shuaigu （率谷GB 8）, Hegu （合谷 LI 4） and LiEque （列缺 LU 7） were selected. After puncturing, reducing method was used routinely and needles were retained for 30 rain. After 2 weeks treatment, migraine specific quality of life questionnaire （MSQ）, visual analogue scale （VAS） and nitric oxide （NO） level in plasma of patients in two groups were observed. Results After treatment, the MSQ, VAS and NO of two groups were significantly improved compared with those before treatment. After treatment, score of MSQ functional limitation was 73.41±10.22 in group A and 60.95 ± 10.15 in group B; the score of MSQ dysfunction was 86.11 ±8.22 in group A and 75.45±8.34 in group B; score of MSQ emotion was 80.51±10.16 in group A and 75.01± 10.20 in group B. The improvements of group A were superior to those of group B, and the differences were all statistically significant （all P〈0.05）. After treatment, the VAS score was 0.93 ± 1.25 in group A and 2.17± 1.70 in group B. The improvement of group A was superior to that of group B, and the difference was statistically significant （P〈0.05）. After treatment, blood plasma NO level was （42.15 ± 16.15） μmol/L in group A and （62.76±15.17） μmol/L in group B. The improvement of group A was superior to that of group B, and the difference was statistically significant （P〈0.05）. Overall response rate was 86.7% （26/30） in group A and 53.3% （16/30） in group B, and the difference between two groups was statistically significant （P〈0.05）. Conclusion Opposing needling is an effective method for the treatment of migraine with the symptom of hyperactivity of liver yong. Its mechanism is to regulate the generation of NO in migraine patients, and improve the relaxation and contraction of cerebral vascular smooth muscle, so as to adjust the cerebral circulation.

Treatment of 85 patients with dysphagia after stroke with deep needling at local glossopharyngeum

Objective To observe the clinical efficacy of deep needling at local glossopharyngeum in treatment of dysphagia after stroke. Methods Deep needling at local glossopharyngeum was applied in 85 patients with dysphagia after stroke. Firstly, quick prick was conducted on lingual surface（mainly at the side of paralysis lingualis）, Jīnjīn（金津 EX-HN 12） and Yùyè（玉液 EX-HN 13） under the tongue; secondly, filiform needle with the length of 75 mm was used to perform quick prick at posterior wall of pharynx at the affected side about three or four times, and then the needle was removed rapidly. Filiform needle with the length of 75 mm was inserted perpendicularly at Liánquán（廉泉 CV 23） towards root of tongue; after deqi, the needle was pushed towards root of tongue in the depth of 60–70 mm, and the needle was retained for 30 min. Meanwhile, the patient was asked to swallow, and the feeling of abnormal deglutition without pain was considered as most appropriate. During needle retention, twirling for reinforcement was applied for two times. The manipulation was conducted once daily, and six days was considered as one course of treatment. Between two courses, one day was free of treatment; and there were four courses in total. Kubota＇s drinking water test evaluation scale was applied to assess the efficacy after the treatment for two weeks and four weeks. Results The score of Kubota＇s drinking water test at the early stage of treatment was 5.08 ± 2.28, the score of evaluation of treatment with deep needling at local glossopharyngeum after treatment for two weeks was 4.56 ± 2.32, and the total effective rate was 89.4%; the score of evaluation after treatment for four weeks was 2.80 ± 2.12, and the total effective rate was 95.3%. Compare before the treatment, the score of Kubota＇s drinking water test was reduced after treatment for two and four weeks（P〈0.05, P〈0.01）. Conclusion Deep needling at local glossopharyngeum in treatment of dysphagia after stroke has good effect.

Observation on therapeutic effects of postoperative enteroparalysis treated with acupuncture

Objective To verify the clinical efficacy of postoperative enteroparalysis treated with acupuncture. Methods One hundred and seven cases of postoperative enteroparalysis were divided into three groups. In group A, 35 cases were immediately treated with acupuncture when routine fasting, gastrointestinal decompression and support treatment were applied at same time; Neiguam （内关 PC 6）, Zusatnli （足三里 ST 36） and Shatngjuxu （上巨虚 ST 37） were selected. In group B, 36 cases were treated by western medicine routine therapy, such as enema, Domperidone or Mosapride with oral administration. In group C, 36 cases were treated with acupuncture as well after 5 days ineffective treatment of western medicine routine therapy; the acupoint selection was as same as that in group A. The curative effect was evaluated after 3 weeks treatment. Results The effective rate of 97.1% （34/35） in group A was superior to that of 58.3% （21/36） in group B and 80.6% （29/36） in group C （both P〈0.05）. The treatment days of cured patients in group A were obviously shorter than that of group B and C （both P〈0.05）. Conclusion Postoperative enteroparalysis can be effectively treated by acupuncture, and the effect will be better with early intervention of acupuncture.

Clinical efficacy of acupuncture at “five spirits acupoints” in treatment of insomnia

Objective To observe the clinical efficacy of acupuncture at ＂five spirits acupoints＂ in treatment of insomnia. Methods The insomnia patients conforming to the diagnostic criteria were included into the study of ＂five spirits acupoints＂, and statistical analysis was conducted over the 65 patients who completed the courses of treatment. Shéntíng（神庭 GV 24）, Běnshén（本神 GB 13）, Sìshéncōng（四神聪 EX-HN 1）, Shéndào（神道 GV 11） and Shénmén（神门 HT 7） were selected. Manipulation： perpendicular insertion was conducted at GV 11 and HT 7, and transverse insertion was conducted at GV 24, GB 13 and EX-HN 1, with the acupuncture depth of 10–15 mm. Even reinforcing and reducing method was applied. Needles were retained at all the selected acupoints, except GV 11, for 25 min. The treatment was conducted every other day, and treatment for 10 times was considered as one course of treatment. After one course, the changes of PSQI, the time to fall asleep, sleep time and soporific dosage were observed before and after treatment. Results According to the comparison before and after treatment, the mean deviation of PSQI, the time to fall asleep, sleep time and soporific dosage were 10.02±1.75,（0.7±0.5） h,（2.1±1.5） h and（10.3±2.5） mg, respectively, all P〈0.05, and the differences were all significant. Conclusion Acupuncture at ＂five spirits acupoints＂ in treatment of insomnia can improve patients’ sleep quality, shorten the time to fall asleep, prolong the actual sleep time, and reduce soporific dosage. With few acupoints selected, superficial needling and small stimulation, acupuncture at ＂five spirits acupoints＂ has better efficacy and is easy to be accepted by patients.

MR study of acupoint and nonacupoint on the impacts of brain functional connectivity

Objective To observe the impacts of acupoint and nonacupoint on brain functional connectivity so as to explore the basis of function specificity of acupoint. Methods Twenty-one healthy volunteers were selected and randomized into acupoint group （12 cases） and nonacupoint group （9 cases）. Acupuncture was applied to bilateral Zusanli （足三里 ST 36） and the site 3 to 4 mm lateral to Zusanli （足三里 ST 36） respectively on the subjects. Rotation needling technique was adopted. MRI was conducted before and 25 min after acupuncture respectively. Bilateral cingular gyrus was taken as seed point to analyze the situations of brain function connectivity in acupoint group and nonacupoint group. Results Brain functional connectivity presented extensively in either acupoint group or nonacupoint group. In comparison between acupoint group and nonacupoint group, in acupoint group, enhanced functional connectivity displayed in bilateral tonsillar, right cerebellar dentate nuclei, bilateral cerebellar uvula, left cerebellar declive, right cerebellar nodule, left inferior frontal gyrus, bilateral middle temporal gyrus, bilateral paracentral Iobule, left cingular gyrus, right superior temporal gyrus, right anterior cingular gyrus and other regions, as well as posterior cingular gyrus. But brain connectivity in bilateral medial frontal gyrus, right inferior frontal gyrus, right cingular gyrus was weakened as compared with nonacupoint group. Conclusion The brain regions with functional connectivity induced are mostly same between acupoint and nonacupoint. But, the strength of brain functional connectivity in acupoint group is higher in overall than that in nonacupoint group.

Traditional Chinese acupuncture manipulations and “dry needling”

In this paper, the authors studied the manipulation of ＂dry needling＂, reviewed Chinese ancient and modern literature of acupuncture-moxibustion, and found that ＂dry needling＂ is very similar to triple needling, superficial needling, joint valley needling, surround needling, and other traditional Chinese acupuncture- moxibustion manipulations; even if in modern China, before and after the invention of ＂dry needling＂, some unique therapies, such as oblique insertion therapy at Ashi point, sliver needling, Fu＇s subcutaneous needling, and long-round needling, were also invented. It can be seen that ＂dry needling＂ therapy is actually a kind of differentiation of traditional Chinese acupuncture- moxibustion in the international communication. The spread of traditional Chinese acupuncture-moxibustion in the West is the basis for the invention of ＂dry needling＂ therapy, and ＂dry needling＂ therapy develops and enriches traditional Chinese acupuncture-moxibustion.

Effect of warm joint needling plus rehabilitation on the balance function and quality of life of patients with spastic hemiplegia after ischemic cerebral stroke

Objective： To observe the effect of warm joint needling plus rehabilitation techniques on the balance function and quality of life （QOL） of patients with spastic hemiplegia after ischemic cerebral stroke. Methods： Ninety patients with spastic hemiplegia after ischemic cerebral stroke were randomized into a rehabilitation group, a warm joint needling group and an observation group, with 30 cases in each group. The rehabilitation group was intervened by Bobath therapy, the warm joint needling group was treated with joint needling on the affected side plus warm needling, and the observation group was given the same rehabilitation treatment as the rehabilitation group together with the same warm joint needling as the warm joint needling group. The three groups were treated once another day, 1 month as a treatment course for 6 months. Before the treatment, and respectively after 2-week, 1-month, 3-month, and 6-month treatment, the modified Ashworth scale （MAS） was used to measure the anti-spasm ability of the lower limb, the Berg balance scale （BBS） was adopted to evaluate the balance function, and the stroke-specific quality of life scale （SS-QOL） was employed to estimate the QOL. Results： After 3-month and 6-month treatment, the lower-limb MAS scores in the observation group were significantly better than those in the rehabilitation group and the warm joint needling group （all P〈0.05）. After 1-month, B-month and 6-month treatment, the BBS scores in the observation group were significantly better than those in the rehabilitation group and the warm joint needling group （all P〈0.05）. After 2-week, 1-month, 3-month and 6-month treatment, the SS-QOL scores in the observation group were markedly better than those in the rehabilitation group and the warm joint needling group （all P〈0.05）. Conclusion： Warm joint needling plus rehabilitation can effectively improve the lower-limb spasticity state, balance function and QOL in patients with spastic hemiplegia after ischemic cerebral stroke.

Observation on lower-reinforcing and upper- reducing acupuncture method for hyperplasia of mammary gland and its influence on estradiol and progesterone

Objective： To observe the clinical effect of lower-reinforcing and upper-reducing acupuncture method for hyperplasia of mammary gland （HMG） and its influence on estradiol （E2） and progesterone （P）. Methods： A randomized, single-blinded and controlled trial was conducted. A total of 124 cases conforming to the inclusion criteria were randomized by random number table into a treatment group and a control group, with 62 cases in each group. Patients in both groups received acupuncture therapy at the same acupoints, while patients in the treatment group received lower-reinforcing and upper-reducing method, and patients in the control group received even reinforcing-reducing manipulation. The treatment started around 10 d before menstruation and was conducted every other day. Patients received 5 treatments in each menstruation cycle for consecutive 3 cycles. The levels of E2, P and E2/P and clinical efficacy were measured before and after treatment. Results： After treatment, the breast lump size, pain intensity and concomitant symptoms score in both groups were substantially lower than those before treatment, showing statistical significances （all P〈0.01）, and the improvement in the treatment group was higher than that in the control group, and the between-group comparisons showed statistical significances （all P〈0.01）. After treatment, the overall effective rate was 91.9% in the treatment group, higher than 72.6% in the control group, and the between-group comparison showed a statistical significance （P〈0.01）. After treatment, levels of E2, P and E2/P value showed no statistical significance when compared with those before treatment in the two groups （all P〉0.05）. Conclusion： Lower-reinforcing and upper-reducing acupuncture method can effectively alleviate clinical symptoms and signs in HMG patients, and produce a better effect than even reinforcing-reducing manipulation. The majority of HMG patients＇ E2, P level and E2/P value were not beyond the normal ranges; therefore, acupuncture showed no substantial influence on E2 and P levels and E2/P value.

Guiding Role of Muscle Region Theory in Acupuncture Anesthesia

As a part of acupuncture system, acupuncture anesthesia can promote the development of acupuncture theory. Muscle region is also a part of acupuncture system and plays a guiding role in clinical application of acupuncture anesthesia. The correlation between the distribution of muscle regions and nerves acts as the substantial foundation of the guiding role. At the same time, acupuncture anesthesia has been promoting the continuous development of muscle region theory. The cyclic development relation between the two （practice-theory-practice） is consistent with the dialectical development view.

Electroacupuncture plus external application of Chinese medicine for knee osteoarthritis

Objective： To reveal the action mechanism and efficacy of electroacupuncture（EA） plus external application of Wei Ling Xian（Radix Clematidis） extract in treating knee osteoarthritis（KOA）, for providing theoretical evidence and novel plan for the treatment of KOA. Methods： Totally 284 inpatients were divided into an EA group and an observation group by the random number table, 142 cases in each group. The EA group was intervened by EA, ultrashort waves, and oral administration of Glucosamine Hydrochloride capsules; while the observation group was by external application of Wei Ling Xian（Radix Clematidis） extract at topical area in addition to the treatment given to the EA group. The intervention lasted 14 d in both groups. X-ray examination of knee joint was ordered before and after treatment, as well as the detection of positive expression of matrix metalloproteinase-1（MMP-1） in cartilage of knee joint, hyaluronic acid（HA） and interleukin-1β（IL-1β） in the inflammatory effusion; the Western Ontario and McM aster Universities osteoarthritis index（WOMAC） and visual analogue scale（VAS） were adopted to evaluate the clinical efficacy. Results： In the observation group, the X-ray examination result of knee joint was significantly improved, the positive expressions of MMP-1 and IL-1β content were significantly decreased, the level of HA was increased, WOMAC and VAS scores dropped, and the total effective rate was 91.5%, which were significantly different from those in the EA group（P〈0.05）. Conclusion： EA plus external application of Wei Ling Xian（Radix Clematidis） extract can produce a more significant efficacy in treating KOA compared to ordinary EA treatment.