以"acupuncture"为主题词及自由词在Pub Med数据库对《New England Journal of Medicine》《The Journal of the American Medical Association》《The Lancet》和《British Medicine Journal》进行检索。检索范围从2005年1月...以"acupuncture"为主题词及自由词在Pub Med数据库对《New England Journal of Medicine》《The Journal of the American Medical Association》《The Lancet》和《British Medicine Journal》进行检索。检索范围从2005年1月—2015年9月,纳入针灸临床试验,对针刺干预手段进行提取并按照"针刺临床试验干预措施报告标准"(Standards of Reporting Interventions in Clinical Trials of Acupuncture,STRICTA)对其针刺细节进行分析。结果表明,即使在高影响因子医学杂志上发表的针灸临床试验文献报告,在针刺细节方面仍然存在诸多不足,这将在一定程度上影响针刺临床疗效评价的客观性,也将直接影响到针刺疗法的国际评价和推广运用。展开更多
目的:评价针刺治疗单纯性肥胖随机对照试验(RCT)的中英文文献报告质量。方法:检索国家知识基础设施数据库(CNKI)、中国生物医学文献数据库(CBM)、中国学术期刊数据库(CSPD)、中文科技期刊数据库(CCD)、Web of Science、PubMed、Embase、...目的:评价针刺治疗单纯性肥胖随机对照试验(RCT)的中英文文献报告质量。方法:检索国家知识基础设施数据库(CNKI)、中国生物医学文献数据库(CBM)、中国学术期刊数据库(CSPD)、中文科技期刊数据库(CCD)、Web of Science、PubMed、Embase、CENTRAL中有关针刺治疗单纯性肥胖的RCT,检索时间2010年1月1日至2020年8月1日,用临床试验报告的统一标准(CONSORT)声明和针刺临床试验干预措施报告(STRICTA)标准中的条目进行文献报告质量评价,对中英文文献进行对比。结果:最终纳入中文文献26篇,英文文献8篇。中、英文文献CONSORT条目报告率分别是33.89%和49.66%。中、英文文献STRICTA条目报告百分比分别是56.11%和66.18%。结论:针刺治疗单纯性肥胖的RCT报告质量较低,且中英文报告质量水平在各方面有不同程度差异。今后研究者需要进一步学习CONSORT声明和STRICTA标准,并提高临床试验设计水平,加强RCT的报告质量。展开更多
The role of allergy in atopic dermatitis is controversial. The atopy patch test (APT) has been used to investigate the association between atopic dermatitis and aeroallergen allergy.To determine the proportion of pati...The role of allergy in atopic dermatitis is controversial. The atopy patch test (APT) has been used to investigate the association between atopic dermatitis and aeroallergen allergy.To determine the proportion of patients with atopic dermatitis with positive patch tests to common local aeroallergens and to compare this to controls with and without respiratory atopy, we performed APT, skin- prick tests (SPT) and IgE radioallergosorbent tests (RAST) on 73 patients with atopic dermatitis and on 38 nonatopic controls (13 with and 25 without respiratory atopy). The allergens used were house dust mite, cat dander, Bermuda grass and German cockroach. Only the APT for house dust mite showed a significant difference between the two groups. APT for house dust mite correlated with the RAST test, while APT for cat fur correlated with the SPT. The APT may be useful to evaluate aeroallergens in atopic dermatitis,but further work is needed to make it more reliable.展开更多
Patients with atopic dermatitis (AD) often have increased skin sensitivity and this symptom often worsens during stress. We sought to find out whether patients with AD had stinging,andto identify the pathocausal neuro...Patients with atopic dermatitis (AD) often have increased skin sensitivity and this symptom often worsens during stress. We sought to find out whether patients with AD had stinging,andto identify the pathocausal neuroimmune mechanisms, including the role of stress. In all, 25 patients with AD with histories of stress worsening were tested using a stinger test. Skin biopsy specimens were processed for immunohistochemistry. Stress inquiries and salivary cortisol tests were performed. In all, 16 patients were stinger-positive and 9 were negative. The stingerpositive papillary dermis had an increased number of mast cells, vasoactive intestinal polypeptide-positive fibers,and a tendency to a higher number of substance P- positive nerve fibers, but a decrease of calcitonin gene- related peptide fibers. Patients who were stinger- positive had a tendency to lower salivary cortisol. The majority of patients with AD experience stinging. Substance P, calcitonin gene-related peptide, vasoactive intestinal polypeptide, and mast cells may have a pathocausal role, as might chronic stress.展开更多
介绍"针刺临床试验干预措施报告标准"(standards for reporting interventions in clinical trials of acupuncture,STRICTA)的临床应用情况,并提出改进意见。STRICTA已广泛应用于针刺临床试验设计、文献撰写及文献质量评价...介绍"针刺临床试验干预措施报告标准"(standards for reporting interventions in clinical trials of acupuncture,STRICTA)的临床应用情况,并提出改进意见。STRICTA已广泛应用于针刺临床试验设计、文献撰写及文献质量评价等各个环节。针对当前STRICTA版本,建议完善"选取穴位的定位标准及定位方法""进针的角度和方向""受试者是否曾接受过针刺"条目,突出辨证论治、择时施治、择期施针的个性化治疗方案,以更好地体现中医辨证施治等传统特色,提升文献的临床利用价值。展开更多
文摘以"acupuncture"为主题词及自由词在Pub Med数据库对《New England Journal of Medicine》《The Journal of the American Medical Association》《The Lancet》和《British Medicine Journal》进行检索。检索范围从2005年1月—2015年9月,纳入针灸临床试验,对针刺干预手段进行提取并按照"针刺临床试验干预措施报告标准"(Standards of Reporting Interventions in Clinical Trials of Acupuncture,STRICTA)对其针刺细节进行分析。结果表明,即使在高影响因子医学杂志上发表的针灸临床试验文献报告,在针刺细节方面仍然存在诸多不足,这将在一定程度上影响针刺临床疗效评价的客观性,也将直接影响到针刺疗法的国际评价和推广运用。
文摘目的:评价针刺治疗单纯性肥胖随机对照试验(RCT)的中英文文献报告质量。方法:检索国家知识基础设施数据库(CNKI)、中国生物医学文献数据库(CBM)、中国学术期刊数据库(CSPD)、中文科技期刊数据库(CCD)、Web of Science、PubMed、Embase、CENTRAL中有关针刺治疗单纯性肥胖的RCT,检索时间2010年1月1日至2020年8月1日,用临床试验报告的统一标准(CONSORT)声明和针刺临床试验干预措施报告(STRICTA)标准中的条目进行文献报告质量评价,对中英文文献进行对比。结果:最终纳入中文文献26篇,英文文献8篇。中、英文文献CONSORT条目报告率分别是33.89%和49.66%。中、英文文献STRICTA条目报告百分比分别是56.11%和66.18%。结论:针刺治疗单纯性肥胖的RCT报告质量较低,且中英文报告质量水平在各方面有不同程度差异。今后研究者需要进一步学习CONSORT声明和STRICTA标准,并提高临床试验设计水平,加强RCT的报告质量。
文摘The role of allergy in atopic dermatitis is controversial. The atopy patch test (APT) has been used to investigate the association between atopic dermatitis and aeroallergen allergy.To determine the proportion of patients with atopic dermatitis with positive patch tests to common local aeroallergens and to compare this to controls with and without respiratory atopy, we performed APT, skin- prick tests (SPT) and IgE radioallergosorbent tests (RAST) on 73 patients with atopic dermatitis and on 38 nonatopic controls (13 with and 25 without respiratory atopy). The allergens used were house dust mite, cat dander, Bermuda grass and German cockroach. Only the APT for house dust mite showed a significant difference between the two groups. APT for house dust mite correlated with the RAST test, while APT for cat fur correlated with the SPT. The APT may be useful to evaluate aeroallergens in atopic dermatitis,but further work is needed to make it more reliable.
文摘Patients with atopic dermatitis (AD) often have increased skin sensitivity and this symptom often worsens during stress. We sought to find out whether patients with AD had stinging,andto identify the pathocausal neuroimmune mechanisms, including the role of stress. In all, 25 patients with AD with histories of stress worsening were tested using a stinger test. Skin biopsy specimens were processed for immunohistochemistry. Stress inquiries and salivary cortisol tests were performed. In all, 16 patients were stinger-positive and 9 were negative. The stingerpositive papillary dermis had an increased number of mast cells, vasoactive intestinal polypeptide-positive fibers,and a tendency to a higher number of substance P- positive nerve fibers, but a decrease of calcitonin gene- related peptide fibers. Patients who were stinger- positive had a tendency to lower salivary cortisol. The majority of patients with AD experience stinging. Substance P, calcitonin gene-related peptide, vasoactive intestinal polypeptide, and mast cells may have a pathocausal role, as might chronic stress.
文摘介绍"针刺临床试验干预措施报告标准"(standards for reporting interventions in clinical trials of acupuncture,STRICTA)的临床应用情况,并提出改进意见。STRICTA已广泛应用于针刺临床试验设计、文献撰写及文献质量评价等各个环节。针对当前STRICTA版本,建议完善"选取穴位的定位标准及定位方法""进针的角度和方向""受试者是否曾接受过针刺"条目,突出辨证论治、择时施治、择期施针的个性化治疗方案,以更好地体现中医辨证施治等传统特色,提升文献的临床利用价值。
