Objective: To observe the therapeutic effects and adverse effects of "channel-oxygen therapy" for extensive anxiety. Methods: Sixty cases of extensive anxiety patients were treated with "channel-oxygen ...Objective: To observe the therapeutic effects and adverse effects of "channel-oxygen therapy" for extensive anxiety. Methods: Sixty cases of extensive anxiety patients were treated with "channel-oxygen therapy" once daily and continuously for 4 weeks. Neiguan(内关PC 6) and Zusanli(足三里ST 36) were needled in combination with nasal inhalation of oxygen, 30 min each session. The therapeutic effects were assessed by Hamilton Anxiety Scale (HAMA) and the adverse effects by Treatment Emergent Symptom Scale (TESS). Results: Of the 60 cases, 35 were cured, 13 improved and 12 were ineffective, with the effective rate being 80.0% and the cured rate 58.3%. No evident adverse effects were found. Conclusion: The "channel-oxygen therapy" is safe and effective for extensive anxiety.展开更多
A single-axis normal-tracking measurement system is proposed, which can solve the problem of measuring large curved surface. According to Collins formula, the tilt dependent error of the measurement system is studied,...A single-axis normal-tracking measurement system is proposed, which can solve the problem of measuring large curved surface. According to Collins formula, the tilt dependent error of the measurement system is studied, which uses Gaussian beam as the light source. By theoretical analysis and numerical simulation, the influence of the error is presented. The results show that there is the difference between point source and Gaussian beam for differential confocal microscopy. The opti-mal diameter of pinhole can be determined by the mathematical model and the actual parameters of the measurement system. The optimal pinhole diameter of this measurement system is 20 to 35 pm for 633 nm wavelength light source.展开更多
Objective:To evaluate the clinical efficacy of acupuncture in the treatment of anxiety state in patients with primary insomnia(PI).Methods:Randomized controlled trials of acupuncture treatment for PI patients with an ...Objective:To evaluate the clinical efficacy of acupuncture in the treatment of anxiety state in patients with primary insomnia(PI).Methods:Randomized controlled trials of acupuncture treatment for PI patients with an anxiety state in Web of Science,Cochrane Library,PubMed,Excerpta Medica Database(EMBASE),China National Knowledge Infrastructure(CNKI),Wanfang Data Knowledge Service Platform(Wanfang),and Chongqing VIP Database(VIP)were retrieved by computer.The retrieval time was from each database’s inception to December 30,2022.Data extraction and evaluation were performed for the included studies.The Cochrane risk of bias assessment tool was used to assess the risk of bias in each article.Meta-analysis of valid data was performed using the RevMan 5.4 software.If the outcome indicator was a categorical variable,relative risk(RR)was used as the effect size.If it was a continuous variable,mean difference(MD)was used to calculate the effect size.Each effect size was expressed as a 95%confidence interval(CI).P<0.05 was considered to indicate a statistically significant difference.Results:A total of 18 studies were included,comprising a total of 1198 patients.The findings of the meta-analysis showed that electroacupuncture had a significant advantage in improving the Hamilton anxiety scale(HAMA)score than benzodiazepines[MD=-1.61,95%CI(-2.17,-1.06),P<0.001].Acupuncture was superior to sham acupuncture[MD=-14.90,95%CI(-20.39,-9.41),P<0.001]and benzodiazepines[MD=-3.39,95%CI(-4.67,-2.12),P<0.001]in reducing the self-rating anxiety scale(SAS)score.Acupuncture was superior to sham acupuncture in reducing the insomnia severity index(ISI)score[MD=-5.61,95%CI(-6.63,-4.89),P<0.001].Acupuncture was superior to benzodiazepines[MD=0.84,95%CI(-1.42,-0.25),P=0.005]and sham acupuncture[MD=-8.39,95%CI(-8.39,-7.86),P<0.001]in improving the Pittsburgh sleep quality index(PSQI)score.Acupuncture had a better effective rate than benzodiazepines[RR=1.16,95%CI(1.08,1.25),P<0.001]and sham acupuncture[RR=8.94,95%CI(4.63,17.25),P<0.001]in treating PI.Conclusion:Acupuncture or electroacupuncture has certain therapeutic advantages over benzodiazepines and sham acupuncture in the treatment of anxiety in PI patients.However,more high-quality randomized controlled trials are needed for further verification.展开更多
Objective:To discuss the clinical efficacy and plausible mechanism of Tiao Yang Qu Xie(regulating Yang to eliminate pathogenic factors)needling method plus paroxetine in treating mild-to-moderate depression.Methods:Si...Objective:To discuss the clinical efficacy and plausible mechanism of Tiao Yang Qu Xie(regulating Yang to eliminate pathogenic factors)needling method plus paroxetine in treating mild-to-moderate depression.Methods:Sixty-six patients with mild-to-moderate depression were divided into an observation group and a control group using the random number table method,each consisting of 33 cases.Another 25 healthy subjects were recruited as a healthy group.The control group took oral paroxetine tablets for treatment,and the observation group received additional acupuncture treatment 3 times weekly.Both groups underwent 4-week treatment.Before treatment,after 2-week and 4-week treatment,and 2 weeks after treatment(follow-up),the patients were assessed using the Hamilton depression scale-17-item(HAMD-17),self-rating depression scale(SDS),self-rating anxiety scale(SAS),and traditional Chinese medicine(TCM)pattern element identification scale for depression.The two groups each randomly contributed 25 cases to detect the protein content of brain-derived neurotrophic factor(BDNF)before treatment and after 4-week treatment,and compared with the healthy group.Results:After 2-week treatment,the markedly effective and total effective rates were significantly higher in the observation group than in the control group(P<0.05);after 4-week treatment,the observation group significantly surpassed the control group in comparing the markedly effective rate(P<0.05).After 2 and 4 weeks of treatment and at the follow-up,the HAMD-17 total score and sleep disorder factor score were lower in the observation group than in the control group(P<0.05);the anxiety-somatic score was lower in the observation group than in the control group after 2-week treatment(P<0.05).After 2 and 4 weeks of treatment and at the follow-up,the observation group was lower than the control group in comparing the scores of SDS,SAS,and TCM pattern element identification scale for depression(P<0.05).After 4-week treatment,the observation group had an increased serum BDNF protein content,higher than that in the control group(P<0.05)and had no significant difference compared to the healthy group(P>0.05).Conclusion:Compared to the use of oral paroxetine alone,acupuncture plus paroxetine can produce more significant efficacy in treating mild-to-moderate depression and act faster in improving sleep disorder and anxiety-somatic symptoms;increasing the serum BDNF protein content may be a part of the mechanism underlying its antidepressant actions.展开更多
This article discussed the mechanisms and precautions of abdominal acupuncture from three different perspectives. First, the relationship between Shénquè (神阙 CV 8) and zang-fu and eight extra meridians s...This article discussed the mechanisms and precautions of abdominal acupuncture from three different perspectives. First, the relationship between Shénquè (神阙 CV 8) and zang-fu and eight extra meridians stated in the ancient literature explained that the theory of CV 8 as the theoretical core of abdominal acupuncture therapy had literature support and theoretical evidence; second, with emphasis on the diagnosis and treatment based on differentiation of syndromes, four methods for selecting the points, including the ones according to hologram, meridians and collaterals, the Ba-kuo (八 廓) and three energizer, meanwhile, the origin of method selecting the points according to Three Energizer and clinical experience was also addressed; third, some problems about the manipulation of abdominal acupuncture therapy were put forward, such as selection of depth, direction, needle tool, as well as personal ideas and precautions, in order to ensure the clinical effect.展开更多
Objective: To observe the clinical effect of acupuncture and hydro-acupuncture in treating anxiety. Methods: Compare between the therapeutic effect of 186 cases of Three Huang Points of DONG's extra points in treat...Objective: To observe the clinical effect of acupuncture and hydro-acupuncture in treating anxiety. Methods: Compare between the therapeutic effect of 186 cases of Three Huang Points of DONG's extra points in treating anxiety and that of 139 cases by purely Western medicine buspirone. Results: The total effective rate of the treatment group was 91.4%, and the rate of the control group was 93.5%. There was statistical difference of Hamilton Anxiety Scale (HAMA) and Self Rating Anxiety Scale (SAS) scores before and after treatment in both groups (P 〈 0.001), while there was no statistical difference between the two groups (P〉0.05). Conclusion: Acupuncture treatment compared favorably to anti-anxiety drug buspirone. Oral administration of buspirone had different degrees of side effects, .such as dizziness, dry mouth, constipation, difficulty urinating and acidophilus, while there was basically no side effects of acupuncture and the effect of acupuncture was better than buspirone. This was especially suitable for patients who could not take medications for various reasons.展开更多
Objective:To observe the clinical efficacy of acupuncture combined with medication for treatment of post-stroke depression (PSD).Methods:A total of 60 patients with PSD in conformity with the inclusion criteria we...Objective:To observe the clinical efficacy of acupuncture combined with medication for treatment of post-stroke depression (PSD).Methods:A total of 60 patients with PSD in conformity with the inclusion criteria were randomly allocated into a treatment group and a control group,with 30 in each.Those in the treatment group were treated with electroacupuncture combined with medication,and those in the control group were treated with medication alone.Before and after treatment,the patients of the two groups were evaluated by means of function independent measure (FIM) and the World Health Organization quality of life-BREF (WHOQOL-BREF).Results:After the treatments,the changes of FIM scores have statistical significant in both of the two groups (P0.01);and the improvement in the treatment group was more remarkable than that in the control group (P0.01).The differences in the scores in various indexes of WHOQOL-BREF in the patients of the two groups before and after treatments were both statistically significant (P0.01,P0.05).And the change in the treatment group was more remarkable than that in the control group (P0.01,P0.05).Conclusion:Electroacupuncture on Niesanzhen (three points on the bitemporal) as major treatment can improve activities of daily living and quality of life for patients with PSD.展开更多
Objective: To explore the therapeutic effects of scalp acupuncture on sleep disorder induced by preexamination anxiety in the undergraduates.Methods: A total of 60 undergraduates with sleep disorder induced by the f...Objective: To explore the therapeutic effects of scalp acupuncture on sleep disorder induced by preexamination anxiety in the undergraduates.Methods: A total of 60 undergraduates with sleep disorder induced by the final examination anxiety were randomized into three groups, named a control group(20 cases), a traditional acupuncture group(20 cases) and a scalp acupuncture group(20 cases). In the control group, no any treatment was given. In the traditional acupuncture group, acupuncture was given at Sìshéncōng(四神聪EX-HN1), bilateral Shénmén(神门HT 7) and bilateral Sānyīnjiāo(三阴交SP 6). The needles were manipulated with the even-needling technique and retained for 30 min. In the scalp acupuncture group, acupuncture was applied to uppermiddle line of occiput(枕上正中线MS 12), middle line of vertex(顶中线MS 5) and middle line of forehead(额中线MS 1). The needles were manipulated with the even-needling technique and retained for 30 min.The treatment was given once a day and 5 treatments made one course. There were 2 days at interval among the courses. The therapeutic effects were analyzed statistically after 4 courses of treatment. Before and after treatment, the Hamilton anxiety scale(HAMA) and the Pittsburgh sleep quality index(PSQI)were adopted to evaluate the conditions of pre-examination anxiety and sleep in the patients.Results: In comparison of PSQI score, compared with those before treatment, the score in the scalp acupuncture group(12.95 ± 1.76 vs 15.95 ± 1.82) and in the traditional acupuncture group(13.75 ± 1.62 vs15.75±1.86) after 1-week of treatment were reduced(both P0.05). Compared with control group, the score in the scalp acupuncture group(12.95 ± 1.76 vs15.78 ± 2.02) and in the traditional acupuncture group(13.75± 1.62 vs 15.78 ± 2.02) were better(both P〈0.05). The difference was not significant between the scalp acupuncture group and the traditional acupuncture group(P0.05). In 2 and 4 weeks of treatment, as well as 1 week after treatment termination, compared with the control group at the same time point, the scores in the scalp acupuncture group(in 2-week treatment: 8.95 ± 1.88 vs 15.94 ± 1.89, in4-week treatment: 5.95 ± 1.05 vs 16.5 ± 1.95, 1 week after treatment termination: 4.7 ± 0.77 vs 9.78 ± 2.10)and the traditional acupuncture group(in 2-week treatment: 11.15 ± 1.31 vs 15.94 ± 1.89, in 4-week treatment: 8.05 ± 0.89 vs 16.5 ±1.95, 1 week after treatment termination: 6.25 ± 0.85 vs 9.78 ±2.10) were all lower(all P0.05) separately. The scores in the scalp acupuncture group were superior to the traditional acupuncture group(all P0.05). In comparison of HAMD score, compared with those before treatment, the score in the scalp acupuncture group(22.4 ± 5.31 vs 25.2 ± 6.18) and in the traditional acupuncture group(22.4 ± 5.31 vs 25 ±5.97) after 1-week of treatment were reduced(both P〈0.05).Compared with control group, the score in the scalp acupuncture group(22.4± 5.31 vs 23.28 ±5.53)and in the traditional acupuncture group(22.4± 5.31 vs 23.28 ±5.53) were better(both P〈0.05). The difference was not significant between the scalp acupuncture group and the traditional acupuncture group(P0.05). In 2 and 4 weeks of treatment, as well as 1 week after treatment termination, compared with the control group at the same time point, the scores in the scalp acupuncture group(in2-week treatment: 18.5 ±4.56 vs 24.22 ± 5.22, in 4-week treatment: 5.8 ±3.52 vs 21.22 ± 6.7,1 week after treatment termination: 4.55 ± 2.72 vs 11.78 ± 9.36) and the traditional acupuncture group(in 2-week treatment: 17.5 ± 4.59 vs 24.22 ± 5.22, in 4-week treatment: 6.95 ± 3.33 vs 21.22 ± 6.7, 1 week after treatment termination: 5.8 ± 2.76 vs 11.78 ± 9.36) were all lower(all P〈0.05) separately. The scores in the scalp acupuncture group were superior to the traditional acupuncture group(all P〈0.05). In 4-week treatment and 1 week after treatment termination, compared with control group, the total effective rates in the traditional acupuncture group(in 4-week treatment: 95% vs 11%, 1 week after treatment termination: 100% vs 83.33%, both P〈0.05) and the scalp acupuncture group(in 4-week treatment: 95% vs 11%, 1 week after treatment termination: 100% vs 83.33%, both P〈0.05) were better and the difference was not significant between the traditional acupuncture group and the scalp acupuncture group(both P0.05).Conclusion: Both scalp acupuncture and traditional acupuncture therapies are effective on sleep disorder induced by pre-examination anxiety in the undergraduates. The scalp acupuncture therapy achieves the better effects on the instant relief of symptoms.展开更多
Objective: To observe the comprehensive curative effect of acupuncture manipulation of regulating governor vessel and unblocking brain for post stroke depression associated with anxiety.Methods: Sixty-four patients ...Objective: To observe the comprehensive curative effect of acupuncture manipulation of regulating governor vessel and unblocking brain for post stroke depression associated with anxiety.Methods: Sixty-four patients with post stroke depression associated with anxiety were randomly divided into 2 groups according to the random numbers generated by spss16.0 software, the group of acupuncture manipulation of regulating governor vessel and unblocking brain(group A) and medication group(group B), with 32 patients in each group. Acupuncture manipulation of regulating governor vessel and unblocking brain was performed in group A.Bǎihuì(百会GV 20), Shéntíng(神庭GV 24), Yǎmén(哑门GV 15) and Dànzhōng(膻中CV 17), Gānshū(肝俞BL 18). Xīnshū(心俞BL 15). Shènshū(肾俞BL 23),Tàichōng(太冲LR 3), Tàixī(太溪KI 3), Shénmén(神门HT 7) and Nèiguān(内关PC 6) were selected. The treatment was conducted for once a day, and 5 times a week. Escitalopram oxalate tablets were given orally to the patients in group B for once a day. The treatment was conducted for 8 consecutive weeks in each group. The scores of Hamilton depression scale(HAMD), Hamilton anxiety scale(HAMA), Barthel index(BI) and Fugl-Meyer assessment(FMA) in the two groups before and after treatment were compared.Results: Comparison with the same group before treatment, HAMD score and HAMA sore in the two groups after treatment for 4 weeks and 8 weeks were all obviously lower than that in the same group before treatment(all P〈0.01); after treatment for 8 weeks, B1 score and FMA score in the two groups were all significantly higher than that in the same group before treatment(all P〈0.01). Comparison between two groups after treatment. HAMD score and HAMA sore in group A after treatment for 4 weeks were significantly lower than that in group B(both P〈0.05); only the HAMA sore in group A after treatment for 8 weeks was lower than that in group B(P〈0.05), and there was no significant difference in HAMD score in the two groups(P〉0.05); after treatment for 8 weeks, FMA score in group A was obviously higher than that in group B(P〈0.05), and there was no significant difference in BI score in the two groups(P〉 0.05).Conclusion: The curative effect of acupuncture manipulation of regulating governor vessel and unblocking brain on the anxiety state and motor function of the patients with post stroke depression is superior to that of escitalopram. With regard to the improvement of depression, this acupuncture manipulation was provided with the characteristic of rapid onset, and its long-term efficacy is equivalent to that of escitalopram. In terms of the improvement of activities of daily living, the curative effect of the two methods is equally well.展开更多
Objective: To observe the clinical efficacy of combined acupuncture and psychological desensitization therapy for anxiety in those with heroin addiction. Methods: All 90 cases were randomly allocated into a treatmen...Objective: To observe the clinical efficacy of combined acupuncture and psychological desensitization therapy for anxiety in those with heroin addiction. Methods: All 90 cases were randomly allocated into a treatment group (45 cases) and a control group (45 cases). Cases in the treatment group received 30 min of combined acupuncture and psychological desensitization therapy for each treatment, twice a week and 8 weeks in total, whereas cases in the control group received no treatment. After that, the anxiety score and state were observed. In addition, the mental state prior to and after cue-elicited heroin craving was evaluated. Results: The total and standard scores of anxiety in the treatment group were significantly reduced compared to the control group (P〈0.05), coupled with a significant reduction of heroin craving (P〈0.01). Conclusion: Combined acupuncture and psychological desensitization can alleviate anxiety and inhibit the short-term heroin craving.展开更多
Objective: To investigate the efficacy of acupuncture in cooperation with moxibustion for treating anxiety. Methods: A treatment group of 42 anxiety patients was treated by acupuncture in cooperation with moxibustio...Objective: To investigate the efficacy of acupuncture in cooperation with moxibustion for treating anxiety. Methods: A treatment group of 42 anxiety patients was treated by acupuncture in cooperation with moxibustion and a control group of 45 anxiety patients, with Western medicine. Results: The total efficacy rate was 92.9% in the treatment group and 71.1% in the control group. There was a significant difference between the two groups (P〈0.01). Conclusion: The effect was significantly better in the treatment group than in the control group. Acupuncture and moxibustion has no side effects and dependence.展开更多
Objective: To observe the clinical effect of acupuncture in treating chronic fatigue syndrome and its effect on anxiety. Methods: Ninety patients who accord with the inclusion criteria were divided into 2 groups, 45...Objective: To observe the clinical effect of acupuncture in treating chronic fatigue syndrome and its effect on anxiety. Methods: Ninety patients who accord with the inclusion criteria were divided into 2 groups, 45 patients in the treatment group received acupuncture therapy, and 45 patients in the control group received medicine therapy. The anxiety state was evaluated with Self-rating Anxiety Scale (SAS) before and after treatments in the two groups. Results: SAS scores of the CFS patients in the two groups decreased after treatment (P〈0.01). There was no statistical difference of the SAS score between the two groups (P〉0.05). Conclusion: Both acupuncture and medicine treatments could improve the anxiety symptoms of CFS patient.展开更多
Objective:To evaluate the clinical efficacy of the Governor Vessel-unblocking and mind-regulating acupuncture method plus repetitive transcranial magnetic stimulation(rTMS)in the treatment of post-stroke insomnia.Meth...Objective:To evaluate the clinical efficacy of the Governor Vessel-unblocking and mind-regulating acupuncture method plus repetitive transcranial magnetic stimulation(rTMS)in the treatment of post-stroke insomnia.Methods:A total of 72 patients with post-stroke insomnia were randomly divided into 2 groups,with 36 cases in each group.The control group received rTMS treatment with a frequency of 1 Hz and a motion threshold value of 90%.The observation group received acupuncture with Governor Vessel-unblocking and mind-regulating method based on the rTMS treatment of the control group.The points were Baihui(GV 20),Shenting(GV 24),Yintang(GV 29),Fengfu(GV 16),Sishencong(EX-HN I),Shenmen(HT I),Sanyinjiao(SP 6);Shenmai(BL 62)and Zhaohai(Kl 6).The treatment was performed once a day for 5 d a week followed by 2 d of rest for 4 weeks.The improvements of Pittsburgh sleep quality index(PSQI),self-rating anxiety scale(SAS)and self-rating depression scale(SDS)scores were observed after treatment,and the clinical efficacy was compared between the two groups.Results:After 4 weeks of treatment,the PSQI,SAS,and SDS scores of the two groups were all reduced,and the intra-group differences were statistically significant(all P<0.001).After treatment,the three scores in the observation group were all lower than those in the control group,and the differences between the two groups were statistically significant(P<0.05,P<0.05,P<0.001).There was a statistically significant difference between the observation group and the control group comparing the clinical efficacy(P<0.05).Conclusion:The therapeutic effect of the Governor Vessel-unblocking and mind-regulating acupuncture method plus rTMS in treating post-stroke insomnia is better than rTMS alone,and it can better improve the anxiety and depression of patients.展开更多
Objective: To observe the effect of electroacupuncture (EA) and herbal cake-partitioned moxibustion on anxiety and depression in patients with Crohn's disease (CD) in remission. Methods: Sixty CD cases were ran...Objective: To observe the effect of electroacupuncture (EA) and herbal cake-partitioned moxibustion on anxiety and depression in patients with Crohn's disease (CD) in remission. Methods: Sixty CD cases were randomly allocated into an EA group (n=30) and an herbal cake-partitioned moxibustion group (n=30) using the random number table by the ratio of 1:1. In addition, 30 healthy subjects were included in a control group. Bilateral Tianshu (ST 25), Qihai (CV 6) and Zhongwan (CV 12) were used in the EA and herbal cake- partitioned moxibustion groups. The treatment was done 3 times a week, for a total of 12 weeks. The efficacy was evaluated using self-rating anxiety scale (SAS), self-rating depression scale (SDS) and traditional Chinese medicine (TCM) symptom scores. Results: Before treatment, the SAS and SDS scores in CD patients were remarkably higher than those in healthy subjects. After EA or herbal cake-partitioned moxibustion treatment, the SAS and SDS scores were significantly decreased in both groups, showing significant intra-group differences (P〈0.05); the symptom scores of abdominal pain (severity, frequency and duration), bowel sounds/flatus and general fatigue were significantly decreased, showing significant intra-group differences (P〈0.05); however, there were no between-group statistical differences (P〉0.05). Conclusion: Both EA and herbal cake-partitioned moxibustion can significantly decrease abnormally high SAS and SDS scores in CD patients as well as TCM symptom scores. The two therapies share similar effects in alleviating common symptoms and improving anxiety and depression.展开更多
文摘Objective: To observe the therapeutic effects and adverse effects of "channel-oxygen therapy" for extensive anxiety. Methods: Sixty cases of extensive anxiety patients were treated with "channel-oxygen therapy" once daily and continuously for 4 weeks. Neiguan(内关PC 6) and Zusanli(足三里ST 36) were needled in combination with nasal inhalation of oxygen, 30 min each session. The therapeutic effects were assessed by Hamilton Anxiety Scale (HAMA) and the adverse effects by Treatment Emergent Symptom Scale (TESS). Results: Of the 60 cases, 35 were cured, 13 improved and 12 were ineffective, with the effective rate being 80.0% and the cured rate 58.3%. No evident adverse effects were found. Conclusion: The "channel-oxygen therapy" is safe and effective for extensive anxiety.
基金Quantity Dissemination and Quality Safety Project of AQSIQ(No.ALC1501)National Key Scientific Instrument and Equipment Development Projects,China(No.2013YQ170539)
文摘A single-axis normal-tracking measurement system is proposed, which can solve the problem of measuring large curved surface. According to Collins formula, the tilt dependent error of the measurement system is studied, which uses Gaussian beam as the light source. By theoretical analysis and numerical simulation, the influence of the error is presented. The results show that there is the difference between point source and Gaussian beam for differential confocal microscopy. The opti-mal diameter of pinhole can be determined by the mathematical model and the actual parameters of the measurement system. The optimal pinhole diameter of this measurement system is 20 to 35 pm for 633 nm wavelength light source.
文摘Objective:To evaluate the clinical efficacy of acupuncture in the treatment of anxiety state in patients with primary insomnia(PI).Methods:Randomized controlled trials of acupuncture treatment for PI patients with an anxiety state in Web of Science,Cochrane Library,PubMed,Excerpta Medica Database(EMBASE),China National Knowledge Infrastructure(CNKI),Wanfang Data Knowledge Service Platform(Wanfang),and Chongqing VIP Database(VIP)were retrieved by computer.The retrieval time was from each database’s inception to December 30,2022.Data extraction and evaluation were performed for the included studies.The Cochrane risk of bias assessment tool was used to assess the risk of bias in each article.Meta-analysis of valid data was performed using the RevMan 5.4 software.If the outcome indicator was a categorical variable,relative risk(RR)was used as the effect size.If it was a continuous variable,mean difference(MD)was used to calculate the effect size.Each effect size was expressed as a 95%confidence interval(CI).P<0.05 was considered to indicate a statistically significant difference.Results:A total of 18 studies were included,comprising a total of 1198 patients.The findings of the meta-analysis showed that electroacupuncture had a significant advantage in improving the Hamilton anxiety scale(HAMA)score than benzodiazepines[MD=-1.61,95%CI(-2.17,-1.06),P<0.001].Acupuncture was superior to sham acupuncture[MD=-14.90,95%CI(-20.39,-9.41),P<0.001]and benzodiazepines[MD=-3.39,95%CI(-4.67,-2.12),P<0.001]in reducing the self-rating anxiety scale(SAS)score.Acupuncture was superior to sham acupuncture in reducing the insomnia severity index(ISI)score[MD=-5.61,95%CI(-6.63,-4.89),P<0.001].Acupuncture was superior to benzodiazepines[MD=0.84,95%CI(-1.42,-0.25),P=0.005]and sham acupuncture[MD=-8.39,95%CI(-8.39,-7.86),P<0.001]in improving the Pittsburgh sleep quality index(PSQI)score.Acupuncture had a better effective rate than benzodiazepines[RR=1.16,95%CI(1.08,1.25),P<0.001]and sham acupuncture[RR=8.94,95%CI(4.63,17.25),P<0.001]in treating PI.Conclusion:Acupuncture or electroacupuncture has certain therapeutic advantages over benzodiazepines and sham acupuncture in the treatment of anxiety in PI patients.However,more high-quality randomized controlled trials are needed for further verification.
文摘Objective:To discuss the clinical efficacy and plausible mechanism of Tiao Yang Qu Xie(regulating Yang to eliminate pathogenic factors)needling method plus paroxetine in treating mild-to-moderate depression.Methods:Sixty-six patients with mild-to-moderate depression were divided into an observation group and a control group using the random number table method,each consisting of 33 cases.Another 25 healthy subjects were recruited as a healthy group.The control group took oral paroxetine tablets for treatment,and the observation group received additional acupuncture treatment 3 times weekly.Both groups underwent 4-week treatment.Before treatment,after 2-week and 4-week treatment,and 2 weeks after treatment(follow-up),the patients were assessed using the Hamilton depression scale-17-item(HAMD-17),self-rating depression scale(SDS),self-rating anxiety scale(SAS),and traditional Chinese medicine(TCM)pattern element identification scale for depression.The two groups each randomly contributed 25 cases to detect the protein content of brain-derived neurotrophic factor(BDNF)before treatment and after 4-week treatment,and compared with the healthy group.Results:After 2-week treatment,the markedly effective and total effective rates were significantly higher in the observation group than in the control group(P<0.05);after 4-week treatment,the observation group significantly surpassed the control group in comparing the markedly effective rate(P<0.05).After 2 and 4 weeks of treatment and at the follow-up,the HAMD-17 total score and sleep disorder factor score were lower in the observation group than in the control group(P<0.05);the anxiety-somatic score was lower in the observation group than in the control group after 2-week treatment(P<0.05).After 2 and 4 weeks of treatment and at the follow-up,the observation group was lower than the control group in comparing the scores of SDS,SAS,and TCM pattern element identification scale for depression(P<0.05).After 4-week treatment,the observation group had an increased serum BDNF protein content,higher than that in the control group(P<0.05)and had no significant difference compared to the healthy group(P>0.05).Conclusion:Compared to the use of oral paroxetine alone,acupuncture plus paroxetine can produce more significant efficacy in treating mild-to-moderate depression and act faster in improving sleep disorder and anxiety-somatic symptoms;increasing the serum BDNF protein content may be a part of the mechanism underlying its antidepressant actions.
文摘This article discussed the mechanisms and precautions of abdominal acupuncture from three different perspectives. First, the relationship between Shénquè (神阙 CV 8) and zang-fu and eight extra meridians stated in the ancient literature explained that the theory of CV 8 as the theoretical core of abdominal acupuncture therapy had literature support and theoretical evidence; second, with emphasis on the diagnosis and treatment based on differentiation of syndromes, four methods for selecting the points, including the ones according to hologram, meridians and collaterals, the Ba-kuo (八 廓) and three energizer, meanwhile, the origin of method selecting the points according to Three Energizer and clinical experience was also addressed; third, some problems about the manipulation of abdominal acupuncture therapy were put forward, such as selection of depth, direction, needle tool, as well as personal ideas and precautions, in order to ensure the clinical effect.
文摘Objective: To observe the clinical effect of acupuncture and hydro-acupuncture in treating anxiety. Methods: Compare between the therapeutic effect of 186 cases of Three Huang Points of DONG's extra points in treating anxiety and that of 139 cases by purely Western medicine buspirone. Results: The total effective rate of the treatment group was 91.4%, and the rate of the control group was 93.5%. There was statistical difference of Hamilton Anxiety Scale (HAMA) and Self Rating Anxiety Scale (SAS) scores before and after treatment in both groups (P 〈 0.001), while there was no statistical difference between the two groups (P〉0.05). Conclusion: Acupuncture treatment compared favorably to anti-anxiety drug buspirone. Oral administration of buspirone had different degrees of side effects, .such as dizziness, dry mouth, constipation, difficulty urinating and acidophilus, while there was basically no side effects of acupuncture and the effect of acupuncture was better than buspirone. This was especially suitable for patients who could not take medications for various reasons.
基金supported by Science and Technology Development Project of Traditional Chinese Medicine of Shandong Province (2007z002-3)
文摘Objective:To observe the clinical efficacy of acupuncture combined with medication for treatment of post-stroke depression (PSD).Methods:A total of 60 patients with PSD in conformity with the inclusion criteria were randomly allocated into a treatment group and a control group,with 30 in each.Those in the treatment group were treated with electroacupuncture combined with medication,and those in the control group were treated with medication alone.Before and after treatment,the patients of the two groups were evaluated by means of function independent measure (FIM) and the World Health Organization quality of life-BREF (WHOQOL-BREF).Results:After the treatments,the changes of FIM scores have statistical significant in both of the two groups (P0.01);and the improvement in the treatment group was more remarkable than that in the control group (P0.01).The differences in the scores in various indexes of WHOQOL-BREF in the patients of the two groups before and after treatments were both statistically significant (P0.01,P0.05).And the change in the treatment group was more remarkable than that in the control group (P0.01,P0.05).Conclusion:Electroacupuncture on Niesanzhen (three points on the bitemporal) as major treatment can improve activities of daily living and quality of life for patients with PSD.
基金Supported by National Students' Program for Innovation and Entrepreneurship Training:201410199052~~
文摘Objective: To explore the therapeutic effects of scalp acupuncture on sleep disorder induced by preexamination anxiety in the undergraduates.Methods: A total of 60 undergraduates with sleep disorder induced by the final examination anxiety were randomized into three groups, named a control group(20 cases), a traditional acupuncture group(20 cases) and a scalp acupuncture group(20 cases). In the control group, no any treatment was given. In the traditional acupuncture group, acupuncture was given at Sìshéncōng(四神聪EX-HN1), bilateral Shénmén(神门HT 7) and bilateral Sānyīnjiāo(三阴交SP 6). The needles were manipulated with the even-needling technique and retained for 30 min. In the scalp acupuncture group, acupuncture was applied to uppermiddle line of occiput(枕上正中线MS 12), middle line of vertex(顶中线MS 5) and middle line of forehead(额中线MS 1). The needles were manipulated with the even-needling technique and retained for 30 min.The treatment was given once a day and 5 treatments made one course. There were 2 days at interval among the courses. The therapeutic effects were analyzed statistically after 4 courses of treatment. Before and after treatment, the Hamilton anxiety scale(HAMA) and the Pittsburgh sleep quality index(PSQI)were adopted to evaluate the conditions of pre-examination anxiety and sleep in the patients.Results: In comparison of PSQI score, compared with those before treatment, the score in the scalp acupuncture group(12.95 ± 1.76 vs 15.95 ± 1.82) and in the traditional acupuncture group(13.75 ± 1.62 vs15.75±1.86) after 1-week of treatment were reduced(both P0.05). Compared with control group, the score in the scalp acupuncture group(12.95 ± 1.76 vs15.78 ± 2.02) and in the traditional acupuncture group(13.75± 1.62 vs 15.78 ± 2.02) were better(both P〈0.05). The difference was not significant between the scalp acupuncture group and the traditional acupuncture group(P0.05). In 2 and 4 weeks of treatment, as well as 1 week after treatment termination, compared with the control group at the same time point, the scores in the scalp acupuncture group(in 2-week treatment: 8.95 ± 1.88 vs 15.94 ± 1.89, in4-week treatment: 5.95 ± 1.05 vs 16.5 ± 1.95, 1 week after treatment termination: 4.7 ± 0.77 vs 9.78 ± 2.10)and the traditional acupuncture group(in 2-week treatment: 11.15 ± 1.31 vs 15.94 ± 1.89, in 4-week treatment: 8.05 ± 0.89 vs 16.5 ±1.95, 1 week after treatment termination: 6.25 ± 0.85 vs 9.78 ±2.10) were all lower(all P0.05) separately. The scores in the scalp acupuncture group were superior to the traditional acupuncture group(all P0.05). In comparison of HAMD score, compared with those before treatment, the score in the scalp acupuncture group(22.4 ± 5.31 vs 25.2 ± 6.18) and in the traditional acupuncture group(22.4 ± 5.31 vs 25 ±5.97) after 1-week of treatment were reduced(both P〈0.05).Compared with control group, the score in the scalp acupuncture group(22.4± 5.31 vs 23.28 ±5.53)and in the traditional acupuncture group(22.4± 5.31 vs 23.28 ±5.53) were better(both P〈0.05). The difference was not significant between the scalp acupuncture group and the traditional acupuncture group(P0.05). In 2 and 4 weeks of treatment, as well as 1 week after treatment termination, compared with the control group at the same time point, the scores in the scalp acupuncture group(in2-week treatment: 18.5 ±4.56 vs 24.22 ± 5.22, in 4-week treatment: 5.8 ±3.52 vs 21.22 ± 6.7,1 week after treatment termination: 4.55 ± 2.72 vs 11.78 ± 9.36) and the traditional acupuncture group(in 2-week treatment: 17.5 ± 4.59 vs 24.22 ± 5.22, in 4-week treatment: 6.95 ± 3.33 vs 21.22 ± 6.7, 1 week after treatment termination: 5.8 ± 2.76 vs 11.78 ± 9.36) were all lower(all P〈0.05) separately. The scores in the scalp acupuncture group were superior to the traditional acupuncture group(all P〈0.05). In 4-week treatment and 1 week after treatment termination, compared with control group, the total effective rates in the traditional acupuncture group(in 4-week treatment: 95% vs 11%, 1 week after treatment termination: 100% vs 83.33%, both P〈0.05) and the scalp acupuncture group(in 4-week treatment: 95% vs 11%, 1 week after treatment termination: 100% vs 83.33%, both P〈0.05) were better and the difference was not significant between the traditional acupuncture group and the scalp acupuncture group(both P0.05).Conclusion: Both scalp acupuncture and traditional acupuncture therapies are effective on sleep disorder induced by pre-examination anxiety in the undergraduates. The scalp acupuncture therapy achieves the better effects on the instant relief of symptoms.
基金Supported by Project of Hebei Provincial Science and Technology Department:Clinical study of the acupuncture manipulation of regulating governor vessel andunblocking brain for treatment of dominant diseases of acupuncture-moxibustion":14277706D~~
文摘Objective: To observe the comprehensive curative effect of acupuncture manipulation of regulating governor vessel and unblocking brain for post stroke depression associated with anxiety.Methods: Sixty-four patients with post stroke depression associated with anxiety were randomly divided into 2 groups according to the random numbers generated by spss16.0 software, the group of acupuncture manipulation of regulating governor vessel and unblocking brain(group A) and medication group(group B), with 32 patients in each group. Acupuncture manipulation of regulating governor vessel and unblocking brain was performed in group A.Bǎihuì(百会GV 20), Shéntíng(神庭GV 24), Yǎmén(哑门GV 15) and Dànzhōng(膻中CV 17), Gānshū(肝俞BL 18). Xīnshū(心俞BL 15). Shènshū(肾俞BL 23),Tàichōng(太冲LR 3), Tàixī(太溪KI 3), Shénmén(神门HT 7) and Nèiguān(内关PC 6) were selected. The treatment was conducted for once a day, and 5 times a week. Escitalopram oxalate tablets were given orally to the patients in group B for once a day. The treatment was conducted for 8 consecutive weeks in each group. The scores of Hamilton depression scale(HAMD), Hamilton anxiety scale(HAMA), Barthel index(BI) and Fugl-Meyer assessment(FMA) in the two groups before and after treatment were compared.Results: Comparison with the same group before treatment, HAMD score and HAMA sore in the two groups after treatment for 4 weeks and 8 weeks were all obviously lower than that in the same group before treatment(all P〈0.01); after treatment for 8 weeks, B1 score and FMA score in the two groups were all significantly higher than that in the same group before treatment(all P〈0.01). Comparison between two groups after treatment. HAMD score and HAMA sore in group A after treatment for 4 weeks were significantly lower than that in group B(both P〈0.05); only the HAMA sore in group A after treatment for 8 weeks was lower than that in group B(P〈0.05), and there was no significant difference in HAMD score in the two groups(P〉0.05); after treatment for 8 weeks, FMA score in group A was obviously higher than that in group B(P〈0.05), and there was no significant difference in BI score in the two groups(P〉 0.05).Conclusion: The curative effect of acupuncture manipulation of regulating governor vessel and unblocking brain on the anxiety state and motor function of the patients with post stroke depression is superior to that of escitalopram. With regard to the improvement of depression, this acupuncture manipulation was provided with the characteristic of rapid onset, and its long-term efficacy is equivalent to that of escitalopram. In terms of the improvement of activities of daily living, the curative effect of the two methods is equally well.
文摘Objective: To observe the clinical efficacy of combined acupuncture and psychological desensitization therapy for anxiety in those with heroin addiction. Methods: All 90 cases were randomly allocated into a treatment group (45 cases) and a control group (45 cases). Cases in the treatment group received 30 min of combined acupuncture and psychological desensitization therapy for each treatment, twice a week and 8 weeks in total, whereas cases in the control group received no treatment. After that, the anxiety score and state were observed. In addition, the mental state prior to and after cue-elicited heroin craving was evaluated. Results: The total and standard scores of anxiety in the treatment group were significantly reduced compared to the control group (P〈0.05), coupled with a significant reduction of heroin craving (P〈0.01). Conclusion: Combined acupuncture and psychological desensitization can alleviate anxiety and inhibit the short-term heroin craving.
文摘Objective: To investigate the efficacy of acupuncture in cooperation with moxibustion for treating anxiety. Methods: A treatment group of 42 anxiety patients was treated by acupuncture in cooperation with moxibustion and a control group of 45 anxiety patients, with Western medicine. Results: The total efficacy rate was 92.9% in the treatment group and 71.1% in the control group. There was a significant difference between the two groups (P〈0.01). Conclusion: The effect was significantly better in the treatment group than in the control group. Acupuncture and moxibustion has no side effects and dependence.
基金supported by Guangdong Province Science and Technology Plan Project(K2060032)
文摘Objective: To observe the clinical effect of acupuncture in treating chronic fatigue syndrome and its effect on anxiety. Methods: Ninety patients who accord with the inclusion criteria were divided into 2 groups, 45 patients in the treatment group received acupuncture therapy, and 45 patients in the control group received medicine therapy. The anxiety state was evaluated with Self-rating Anxiety Scale (SAS) before and after treatments in the two groups. Results: SAS scores of the CFS patients in the two groups decreased after treatment (P〈0.01). There was no statistical difference of the SAS score between the two groups (P〉0.05). Conclusion: Both acupuncture and medicine treatments could improve the anxiety symptoms of CFS patient.
文摘Objective:To evaluate the clinical efficacy of the Governor Vessel-unblocking and mind-regulating acupuncture method plus repetitive transcranial magnetic stimulation(rTMS)in the treatment of post-stroke insomnia.Methods:A total of 72 patients with post-stroke insomnia were randomly divided into 2 groups,with 36 cases in each group.The control group received rTMS treatment with a frequency of 1 Hz and a motion threshold value of 90%.The observation group received acupuncture with Governor Vessel-unblocking and mind-regulating method based on the rTMS treatment of the control group.The points were Baihui(GV 20),Shenting(GV 24),Yintang(GV 29),Fengfu(GV 16),Sishencong(EX-HN I),Shenmen(HT I),Sanyinjiao(SP 6);Shenmai(BL 62)and Zhaohai(Kl 6).The treatment was performed once a day for 5 d a week followed by 2 d of rest for 4 weeks.The improvements of Pittsburgh sleep quality index(PSQI),self-rating anxiety scale(SAS)and self-rating depression scale(SDS)scores were observed after treatment,and the clinical efficacy was compared between the two groups.Results:After 4 weeks of treatment,the PSQI,SAS,and SDS scores of the two groups were all reduced,and the intra-group differences were statistically significant(all P<0.001).After treatment,the three scores in the observation group were all lower than those in the control group,and the differences between the two groups were statistically significant(P<0.05,P<0.05,P<0.001).There was a statistically significant difference between the observation group and the control group comparing the clinical efficacy(P<0.05).Conclusion:The therapeutic effect of the Governor Vessel-unblocking and mind-regulating acupuncture method plus rTMS in treating post-stroke insomnia is better than rTMS alone,and it can better improve the anxiety and depression of patients.
基金supported by National Basic Research Program of China 973 Program(No.2015CB554501,No.2009CB522900)Shanghai Rising-star Program(No.16QA1403400)the Program for New Century Excellent Talents in University of Ministry of Education(No.NCET-13-0907)~~
文摘Objective: To observe the effect of electroacupuncture (EA) and herbal cake-partitioned moxibustion on anxiety and depression in patients with Crohn's disease (CD) in remission. Methods: Sixty CD cases were randomly allocated into an EA group (n=30) and an herbal cake-partitioned moxibustion group (n=30) using the random number table by the ratio of 1:1. In addition, 30 healthy subjects were included in a control group. Bilateral Tianshu (ST 25), Qihai (CV 6) and Zhongwan (CV 12) were used in the EA and herbal cake- partitioned moxibustion groups. The treatment was done 3 times a week, for a total of 12 weeks. The efficacy was evaluated using self-rating anxiety scale (SAS), self-rating depression scale (SDS) and traditional Chinese medicine (TCM) symptom scores. Results: Before treatment, the SAS and SDS scores in CD patients were remarkably higher than those in healthy subjects. After EA or herbal cake-partitioned moxibustion treatment, the SAS and SDS scores were significantly decreased in both groups, showing significant intra-group differences (P〈0.05); the symptom scores of abdominal pain (severity, frequency and duration), bowel sounds/flatus and general fatigue were significantly decreased, showing significant intra-group differences (P〈0.05); however, there were no between-group statistical differences (P〉0.05). Conclusion: Both EA and herbal cake-partitioned moxibustion can significantly decrease abnormally high SAS and SDS scores in CD patients as well as TCM symptom scores. The two therapies share similar effects in alleviating common symptoms and improving anxiety and depression.