Based on the model of the two calcium stores developed by Goldbeter, the influence of external magnetic field on the calcium concentration has been discussed. We believe that the cell membrane is a major site of inter...Based on the model of the two calcium stores developed by Goldbeter, the influence of external magnetic field on the calcium concentration has been discussed. We believe that the cell membrane is a major site of interaction for extremely-low-frequency (ELF) electromagnetic fields, and the permeability of ions can be changed with the changing electromagnetic fields. It is shown that magnetic field initiates intraeellular calcium oscillation with a threshold in flux density, and that the calcium oscillations do not occur if the density of magnetic field is below the threshold. The results of theoretical calculation are consistent with that of the experiment. The intracellular free calcium concentrations of different cells exposed to the same magnetic fields are different from each other. It is indicated that the different behaviors such as oscillation, rise and invariability of calcium concentration are associated with the sort of cells.展开更多
基金supported by National Natural Science Foundation of Foundation under Grant No.C2007000026the Research Fond for the Doctoral Program of Higher Education under Grant No.20060080001
文摘Based on the model of the two calcium stores developed by Goldbeter, the influence of external magnetic field on the calcium concentration has been discussed. We believe that the cell membrane is a major site of interaction for extremely-low-frequency (ELF) electromagnetic fields, and the permeability of ions can be changed with the changing electromagnetic fields. It is shown that magnetic field initiates intraeellular calcium oscillation with a threshold in flux density, and that the calcium oscillations do not occur if the density of magnetic field is below the threshold. The results of theoretical calculation are consistent with that of the experiment. The intracellular free calcium concentrations of different cells exposed to the same magnetic fields are different from each other. It is indicated that the different behaviors such as oscillation, rise and invariability of calcium concentration are associated with the sort of cells.