In the past ^68Ge （Germanium-68） was purified with toxic organic solvents in liquid-liquid extractions making the product unacceptable by the FDA （food and drug Administration） for human use. The authors report in...In the past ^68Ge （Germanium-68） was purified with toxic organic solvents in liquid-liquid extractions making the product unacceptable by the FDA （food and drug Administration） for human use. The authors report initial studies utilizing three or four columns consisting of sequences of AG 1, AG50, Chelex 100 and/or Sephadex G25 resins. Five purification methods were examined and a separation consisting of the sequence： AG 1-Chelex100-Sephedex G25 provided 87% recovery of germanium. Fractionation of the elution resulted in high germanium concentrations.展开更多
文摘In the past ^68Ge （Germanium-68） was purified with toxic organic solvents in liquid-liquid extractions making the product unacceptable by the FDA （food and drug Administration） for human use. The authors report initial studies utilizing three or four columns consisting of sequences of AG 1, AG50, Chelex 100 and/or Sephadex G25 resins. Five purification methods were examined and a separation consisting of the sequence： AG 1-Chelex100-Sephedex G25 provided 87% recovery of germanium. Fractionation of the elution resulted in high germanium concentrations.
