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胸部手术后硬膜外腔自控镇痛治疗的临床观察 被引量:2
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作者 黄文起 黑子清 +2 位作者 陈宇 吴昌彬 肖亮灿 《中山大学学报(医学科学版)》 CAS CSCD 1998年第S1期88-89,共2页
目的:研究胸部手术病人术后有效的镇痛方式。方法:采用硬膜外腔自控镇痛技术(PCA),观察吗啡0.12mg/(kg·d)、芬太尼10μg/(kg·d)硬膜外腔用药对胸科手术后镇痛效果。结果:吗啡和芬太尼在72h... 目的:研究胸部手术病人术后有效的镇痛方式。方法:采用硬膜外腔自控镇痛技术(PCA),观察吗啡0.12mg/(kg·d)、芬太尼10μg/(kg·d)硬膜外腔用药对胸科手术后镇痛效果。结果:吗啡和芬太尼在72h内硬膜外腔持续用药,镇痛效果满意,呼吸循环无明显变化。结论:吗啡和芬太尼硬膜外腔用药,能产生安全。 展开更多
关键词 镇痛.硬膜外腔/方法 镇痛.病人控制/方法 胸部疾病/外科学 吗啡/治疗应用 芬太尼/治疗应用
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潜伏期硬膜外分娩镇痛在子痫前期患者中的应用 被引量:23
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作者 李莉 吕艳 崔洪艳 《中华围产医学杂志》 CAS CSCD 北大核心 2019年第2期113-117,共5页
目的探讨潜伏期硬膜外分娩镇痛对于子痫前期患者母婴安全性的影响。方法对2016年8月至2017年7月在天津市中心妇产科医院自愿接受分娩镇痛的单胎、头位的80例子痫前期患者进行前瞻性研究,根据随机数码表法分为活跃期组(宫口≥4cm时实施... 目的探讨潜伏期硬膜外分娩镇痛对于子痫前期患者母婴安全性的影响。方法对2016年8月至2017年7月在天津市中心妇产科医院自愿接受分娩镇痛的单胎、头位的80例子痫前期患者进行前瞻性研究,根据随机数码表法分为活跃期组(宫口≥4cm时实施硬膜外分娩镇痛)和潜伏期组(产妇临产后即实施分娩镇痛),每组40例。于镇痛前及镇痛后产程的不同时点,采用视觉模拟评分(visual analogue score,VAS)对产妇进行疼痛评估。于临产后及胎儿娩出后分别抽取产妇静脉血,采用酶联免疫吸附法(enzyme-linked immunosorbent assay,ELISA)检测血清皮质醇和血浆促肾上腺素皮质激素(adrenocorticotropic hormone,ACTH)浓度。采用t检验或χ2检验对数据进行统计分析。结果(1)潜伏期组产妇第一产程时间[(521.3±103.5)与(570.3±116.2)min,t=0.366],给予镇痛药物即刻、宫口开至2及3cm时VAS评分[分别为(4.1±1.1)与(7.3±1.2)分,(3.5±0.9)与(7.6±1.7)分,(3.7±0.7)与(8.1±1.4)分,t值分别为4.387、9.652及5.321]及宫口开至2、3cm时平均动脉压[分别为(98.3±9.1)与(125.3±10.6)mmHg(1mmHg=0.133kPa),(98.6±10.4)与(127.5±9.6)mmHg,t值分别为8.014及5.496],剖宫产率[15.0%(6/40)与27.5%(11/40),χ^2=4.012]均低于活跃期组(P值均<0.05)。(2)潜伏期组和活跃期组产妇胎儿娩出后血清皮质醇[分别为(457±79)与(233±55)nmol/L,(565±76)与(231±64)nmol/L,t值分别为5.126及6.028]和血浆ACTH浓度[分别为(71±16)与(39±10)pg/ml,(81±14)与(38±11)pg/ml,t值分别为6.028及5.984]均高于临产后(P值均<0.05)。潜伏期组产妇胎儿娩出后血清皮质醇和血浆ACTH浓度均低于活跃期组(t值分别为5.009和3.862,P值均<0.05)。结论潜伏期硬膜外分娩镇痛可安全用于子痫前期产妇,尽早、尽快地缓解产痛,降低产妇的应激反应,维持产妇循环稳定。 展开更多
关键词 子痫前期 镇痛.硬膜外 镇痛 产程 自然分娩 产程 第一
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连续硬膜外自控镇痛对剖宫产术后产妇恢复及血清泌乳素的影响 被引量:7
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作者 唐萍 《中国医师进修杂志》 2011年第33期31-33,共3页
目的探讨连续硬膜外自控镇痛对剖宫产术后产妇恢复及血清泌乳素的影响。方法将86例行剖宫产术产妇按随机数字表法分为两组,观察组43例采用连续硬膜外自控镇痛,对照组43例采用哌替啶肌肉注射,比较两组的镇痛效果及血清泌乳素水平变化... 目的探讨连续硬膜外自控镇痛对剖宫产术后产妇恢复及血清泌乳素的影响。方法将86例行剖宫产术产妇按随机数字表法分为两组,观察组43例采用连续硬膜外自控镇痛,对照组43例采用哌替啶肌肉注射,比较两组的镇痛效果及血清泌乳素水平变化。结果观察组镇痛优良率[79.1%(34/43)]明显高于对照组[20.9%(9/43)](P〈0.05)。观察组术后泌乳素水平[(542.17±46.75)μg/L]较术前[(351.13±20.92)μg/L]明显升高(P〈0.05),且明显高于对照组术后[(362.12±24.33)μg/L](P〈0.05)。观察组的初乳时间[(15.21±3.26)h]明显早于对照组[(21.16±4.78)h](P〈0.05)。结论连续硬膜外自控镇痛对剖宫产术后产妇进行镇痛,可以达到良好的镇痛效果,有利于产妇的恢复,促进血清泌乳素的分泌,值得临床推广应用。 展开更多
关键词 镇痛.硬膜外 剖宫产术 催乳素
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A comparison of maternal fear of childbirth,labor pain intensity and intrapartum analgesic consumption between primiparas and multiparas:A cross-sectional study 被引量:10
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作者 Yongfang Deng Yan Lin +5 位作者 Liyuan Yang Qiuxia Liang Bailing Fu Huixian Li Huizhu Zhang Yan Liu 《International Journal of Nursing Sciences》 CSCD 2021年第4期380-387,I0002,共9页
Objectives:To describe and compare fear of childbirth and in-labor pain intensity between primiparas and multiparas and explore the association between the amount of actual pain relief and fear of childbirth.Methods:A... Objectives:To describe and compare fear of childbirth and in-labor pain intensity between primiparas and multiparas and explore the association between the amount of actual pain relief and fear of childbirth.Methods:A convenience sampling method was used.A total of 260 women undergoing spontaneous or induced labor,including 97 primiparas and 163 multiparas,were recruited in a large academic specialized hospital in Guangzhou,China,from February 2018 to August 2019.The clinical data of maternal and neonatal were extracted from a structured electronic medical record system.Other demographic information,such as employment and family monthly income,was collected by a questionnaire.The Numeric Rating Scale(NRS)and the Chinese version of the Childbirth Attitude Questionnaire(C-CAQ)were applied to assess maternal in-labor pain intensity and fear of childbirth.The analgesic consumption and the frequency of manual boluses as rescue analgesia were stored and collected from the analgesia pump.Results:Eighty-two(84.5%)primiparas and ninety-nine(60.7%)multiparas received epidural analgesia(P<0.001).In the epidural subgroup,the primiparous average fear of childbirth(36.46±10.93)was higher than that of the multiparas(32.06±10.23)(P¼0.007).However,multiparas reported more intense in-labor pain[8.0(8.0,9.0)vs.8.0(7.0,8.0)],had more successful manual boluses per hour[2.68(1.65,3.85)vs.1.77(0.90,2.47)],more hourly analgesic consumption[23.00(16.00,28.25)vs.17.24(11.52,21.36)mL]and more average analgesic consumption[0.35(0.24,0.45)vs.0.26(0.19,0.35)mL/(h$kg)]than the primiparas(P<0.05).Spearman’s correlation analysis showed that the maximum in-labor pain was weakly positively correlated with fear of childbirth(r¼0.09)(P<0.05),hourly analgesic consumption(r¼0.16)(P<0.01)and average analgesic consumption(r¼0.17)(P<0.05).No statistically significant association was uncovered between analgesic consumption and maternal fear of childbirth.Conclusions:Fear of childbirth is a potential predictor of labor pain intensity.Further study is needed to explore its role and value in pain management during delivery.Parity is not a determinant of pain relief use and should not be a preconceived preference of obstetric care team members to determine the distribution of epidural analgesia,especially when analgesia resources are insufficient. 展开更多
关键词 Epidural analgesia FEAR Labor pain Obstetrics and gynecology department of the hospital Parity PARTURITION
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CLINICAL EFFECTS OF ROPIVACAINE MESYLATE IN EPIDURAL ANESTHESIA AND ANALGESIA 被引量:1
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作者 Jian-qingXu BoZhu Tie-huYe 《Chinese Medical Sciences Journal》 CAS CSCD 2005年第1期70-73, ,共4页
关键词 epidural anesthesia postoperative analgesia ropivacaine mesylate ropivacaine hydrochloride
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