A cross point assignment algorithm is proposed under consideration of very long nets (LCPA).It is to consider not only the cost of connection between cross points and pins and the exclusive cost among cross points on ...A cross point assignment algorithm is proposed under consideration of very long nets (LCPA).It is to consider not only the cost of connection between cross points and pins and the exclusive cost among cross points on the boundary of a global routing cell,but also the cost of displacement among cross points of the same net.The experiment results show that the quality and speed in the following detailed routing are improved obviously,especially for very long nets.展开更多
AIM: To investigate the effect of vascular endothelial growth factor (VEGF) transfection on hepatic sinusoidal capillarization. METHODS: Enhanced green fluorescent protein (EGFP)/ VEGF transfection was confirmed by im...AIM: To investigate the effect of vascular endothelial growth factor (VEGF) transfection on hepatic sinusoidal capillarization. METHODS: Enhanced green fluorescent protein (EGFP)/ VEGF transfection was confirmed by immunofluorescence microscopy and immunohistoche-mistry both in primary hepatocytes and in normal liver. Cirrhotic rats were generated by thioacetamide (TAA) administration and then divided into a treatment group, which received injections of 400 μg of plasmid DNA encoding an EGFP- VEGF fusion protein, and a blank group, which received an equal amount of normal saline through the portal vein. The portal vein pressure was measured in the normal and cirrhotic state, in treated and blank groups. The average number of fenestrae per hepatic sinusoid was determined using transmission electron microscopy (TEM), while the relative abundance of VEGF transcripts was examined by Gene array. RESULTS: Green fluorescent protein was observed in the cytoplasms of liver cells under immunofluorescence microscopy 24 h after transfection with EGFP/VEGF plasmid in vitro. Staining with polyclonal antibodies against VEGF illustrated that hepatocytes expressedimmunodetectable VEGF both in vitro and in vitro. There were significant differences in the number of fenestrae and portal vein pressures between normal and cirrhotic rats (7.40 ± 1.71 vs 2.30 ± 1.16 and 9.32 ± 0.85 cmH2O vs 17.92 ± 0.90 cmH2O, P < 0.01), between cirrhotic and treated rats (2.30 ± 1.16 cmH2O vs 4.60 ± 1.65 and 17.92 ± 0.90 cmH2O vs 15.52 ± 0.93 cmH2O, P < 0.05) and between the treatment group and the blank group (4.60 ± 1.65 cmH2O vs 2.10 ± 1.10 cmH2O and 15.52 ± 0.93 cmH2O vs 17.26 ± 1.80 cmH2O, P < 0.05). Gene- array analysis revealed that the relative abundance of transcripts of VEGF family members decreased in the cirrhotic state and increased after transfection. CONCLUSION: Injection of a plasmid encoding VEGF through the portal vein is an effective method to induce the formation of fenestrae and decrease portal vein pressure in cirrhotic rats. Therefore, it may be a good choice for treating hepatic cirrhosis and portal hypertension.展开更多
In the knitting industry the measurements of the stitch density and the stitch length are usually done manually, which may lead to lower efficiency and less definition and also bring subjective ideas into the test res...In the knitting industry the measurements of the stitch density and the stitch length are usually done manually, which may lead to lower efficiency and less definition and also bring subjective ideas into the test results. In order to improve the effect we can measure with Digital Image Processing Techniques. A piece of sample is scanned into computer and changed into a digital image, which is processed with media filtering. To acquire the power spectrum, the image in the spatial domain is converted into the frequency domain. Picking up the characteristic points describing the stitch density and the stitch length separately in the power spectra and reconstructing them, the values of the stitch density and the stitch length could be calculated. When measuring the stitch length, we should establish a geometric model of the stitch based en the digital image processing, which provides a method to transform the stitch length in the two-dimensien space into the three-dimensien space and to measure the value of the stitch length more accurately. This method also provides a new way to measure the stitch length without damaging the fabric.展开更多
By constructing a Gray map, a class of constacyclic codes over ring R = R+ vR is studied. Using cyclic codes and negacyclic codes of length p^s over ring R, the structure of (1 - 2v)-constacyclic codes and dual cod...By constructing a Gray map, a class of constacyclic codes over ring R = R+ vR is studied. Using cyclic codes and negacyclic codes of length p^s over ring R, the structure of (1 - 2v)-constacyclic codes and dual codes of length p^s over ring R are given, the Gray images of (1 - 2v)-constacyclic codes in a particular case are also studied. It is shown that linear codes of length pS over ring R are (1 -2v)-constacyclic codes if and only if their Gray images are distance-invariant cyclic codes of length 2p^s over ring R.展开更多
文摘A cross point assignment algorithm is proposed under consideration of very long nets (LCPA).It is to consider not only the cost of connection between cross points and pins and the exclusive cost among cross points on the boundary of a global routing cell,but also the cost of displacement among cross points of the same net.The experiment results show that the quality and speed in the following detailed routing are improved obviously,especially for very long nets.
基金The National Natural Science Fundation of China, No. 30300341The Natural Science Fundation of Shandong Province, No. Y2004Z12
文摘AIM: To investigate the effect of vascular endothelial growth factor (VEGF) transfection on hepatic sinusoidal capillarization. METHODS: Enhanced green fluorescent protein (EGFP)/ VEGF transfection was confirmed by immunofluorescence microscopy and immunohistoche-mistry both in primary hepatocytes and in normal liver. Cirrhotic rats were generated by thioacetamide (TAA) administration and then divided into a treatment group, which received injections of 400 μg of plasmid DNA encoding an EGFP- VEGF fusion protein, and a blank group, which received an equal amount of normal saline through the portal vein. The portal vein pressure was measured in the normal and cirrhotic state, in treated and blank groups. The average number of fenestrae per hepatic sinusoid was determined using transmission electron microscopy (TEM), while the relative abundance of VEGF transcripts was examined by Gene array. RESULTS: Green fluorescent protein was observed in the cytoplasms of liver cells under immunofluorescence microscopy 24 h after transfection with EGFP/VEGF plasmid in vitro. Staining with polyclonal antibodies against VEGF illustrated that hepatocytes expressedimmunodetectable VEGF both in vitro and in vitro. There were significant differences in the number of fenestrae and portal vein pressures between normal and cirrhotic rats (7.40 ± 1.71 vs 2.30 ± 1.16 and 9.32 ± 0.85 cmH2O vs 17.92 ± 0.90 cmH2O, P < 0.01), between cirrhotic and treated rats (2.30 ± 1.16 cmH2O vs 4.60 ± 1.65 and 17.92 ± 0.90 cmH2O vs 15.52 ± 0.93 cmH2O, P < 0.05) and between the treatment group and the blank group (4.60 ± 1.65 cmH2O vs 2.10 ± 1.10 cmH2O and 15.52 ± 0.93 cmH2O vs 17.26 ± 1.80 cmH2O, P < 0.05). Gene- array analysis revealed that the relative abundance of transcripts of VEGF family members decreased in the cirrhotic state and increased after transfection. CONCLUSION: Injection of a plasmid encoding VEGF through the portal vein is an effective method to induce the formation of fenestrae and decrease portal vein pressure in cirrhotic rats. Therefore, it may be a good choice for treating hepatic cirrhosis and portal hypertension.
文摘In the knitting industry the measurements of the stitch density and the stitch length are usually done manually, which may lead to lower efficiency and less definition and also bring subjective ideas into the test results. In order to improve the effect we can measure with Digital Image Processing Techniques. A piece of sample is scanned into computer and changed into a digital image, which is processed with media filtering. To acquire the power spectrum, the image in the spatial domain is converted into the frequency domain. Picking up the characteristic points describing the stitch density and the stitch length separately in the power spectra and reconstructing them, the values of the stitch density and the stitch length could be calculated. When measuring the stitch length, we should establish a geometric model of the stitch based en the digital image processing, which provides a method to transform the stitch length in the two-dimensien space into the three-dimensien space and to measure the value of the stitch length more accurately. This method also provides a new way to measure the stitch length without damaging the fabric.
基金supported by the National Natural Science Foundation of China under Grant No.61370089
文摘By constructing a Gray map, a class of constacyclic codes over ring R = R+ vR is studied. Using cyclic codes and negacyclic codes of length p^s over ring R, the structure of (1 - 2v)-constacyclic codes and dual codes of length p^s over ring R are given, the Gray images of (1 - 2v)-constacyclic codes in a particular case are also studied. It is shown that linear codes of length pS over ring R are (1 -2v)-constacyclic codes if and only if their Gray images are distance-invariant cyclic codes of length 2p^s over ring R.