The effect of Ru on γ' precipitation behavior and evolution in single crystal superalloys with different Ru contents were investigated by scanning electron microscopy with energy dispersive spectroscopy,3D atomic pr...The effect of Ru on γ' precipitation behavior and evolution in single crystal superalloys with different Ru contents were investigated by scanning electron microscopy with energy dispersive spectroscopy,3D atomic probing,differential scanning calorimetry.The results show that the solvus of the γ' phase decreases gradually with increasing Ru content in the alloys by casting or by the same solution and aging treatments,the alloy with a larger Ru content yields a smaller γ' phase.The addition of Ru increases the growth rate and coarsening rate of the γ' phase.Ru mainly distributes in the γ phase,which causes more Re and Mo partition into the γ' phase,increasing the absolute value of mismatch and the rafting rate of the γ' phase.展开更多
The tidal current duration (TCD) and velocity (TCV) and suspended sediment concentration (SSC) were measured in the dry season in December, 2011 and in the flood season in June, 2012 at the upper part of the Nor...The tidal current duration (TCD) and velocity (TCV) and suspended sediment concentration (SSC) were measured in the dry season in December, 2011 and in the flood season in June, 2012 at the upper part of the North Channel of Changjiang Estuary. They were assimilated with the measured data in 2003, 2004, 2006 and 2007, using the tidal range's proportion conversion. Variations in TCD and TCV, preferential flow and SSC have been calculated. Influences of typical engineering projects such as Qingcaosha fresh water reservoir, Yangtze River Bridge, and land reclamation on the ebb and flood TCD, TCV and SSC in the North Channel for the last 10 years are discussed. The results show that: (1) currently, in the upper part of North Channel, the ebb tide dominates; after the construction of the typical projects, ebb TCD and TCV tends to be larger and the vertical average ebb and flood SSC decrease during the flood season while SSC increases during the dry season; (2) changes in the vertical average TCV are mainly contributed by seasonal runoff variation during the flood season, which is larger in the flood season than that in the dry season; the controlling parameters of increasing ebb TCD and TCV are those large-scale engineering projects in the North Channel; variation in SSC may result mainly from the reduction of basin annual sediment loads, large-scale nearshore projects and so on.展开更多
With the help of FESEM, high resolution electron backscatter diffraction can investigate the grains/subgrains as small as a few tens of nanometers with a good angular resolution (~0.5°). Fast development of EBS...With the help of FESEM, high resolution electron backscatter diffraction can investigate the grains/subgrains as small as a few tens of nanometers with a good angular resolution (~0.5°). Fast development of EBSD speed (up to 1100 patterns per second) contributes that the number of published articles related to EBSD has been increasing sharply year by year. This paper reviews the sample preparation, parameters optimization and analysis of EBSD technique, emphasizing on the investigation of ultrafine grained and nanostructured materials processed by severe plastic deformation (SPD). Detailed and practical parameters of the electropolishing, silica polishing and ion milling have been summarized. It is shown that ion milling is a real universal and promising polishing method for EBSD preparation of almost all materials. There exists a maximum value of indexed points as a function of step size. The optimum step size depends on the magnification and the board resolution/electronic step size. Grains/subgrains and texture, and grain boundary structure are readily obtained by EBSD. Strain and stored energy may be analyzed by EBSD.展开更多
Based on observed temperature data since the 1950s, long-term variability of the summer sharp thermocline in the Yellow Sea Cold Water Mass (YSCWM) and East China Sea Cold Eddy (ECSCE) areas is examined. Relations...Based on observed temperature data since the 1950s, long-term variability of the summer sharp thermocline in the Yellow Sea Cold Water Mass (YSCWM) and East China Sea Cold Eddy (ECSCE) areas is examined. Relationships between the thermocline and atmospheric and oceanic forcing were investigated using multiyear wind, Kuroshio discharge and air temperature data. Results show that: 1) In the YSCWM area, thermocline strength shows about 4-year and 16-year period oscillations. There is high correlation between summer thermocline strength and local atmospheric temperature in summer and the previous winter; 2) In the ECSCE area, interannual oscillation of thermocline strength with about a 4-year period (stronger in El Nifio years) is strongly correlated with that of local wind stress. A transition from weak to strong thermocline during the mid 1970s is consistent with a 1976/1977 climate shift and Kuroshio volume transport; 3) Long-term changes of the thermocline in both regions are mainly determined by deep layer water, especially on the decadal timescale. However, surface water can modify the thermocline on an interannual timescale in the YSCWM area.展开更多
This study examined the rainfall around the middle and lower reaches of the Yangtze River and related atmospheric circulation by using NCEP reanalysis data. The purpose of this study is to analyze their decadal variat...This study examined the rainfall around the middle and lower reaches of the Yangtze River and related atmospheric circulation by using NCEP reanalysis data. The purpose of this study is to analyze their decadal variation and the relationship among rainfall, atmospheric circulation around East Asia and the ENSO episodes. Current results are presented as follows: (1) Very clear increasing trend of the rainfall around the middle and low reaches of the Yangtze River during the Meiyu period and June to July is found in the recent 15 years. Meanwhile, the geopotential height at 500 hPa around the Okhotsk Sea also holds similar increasing trend. It is noticeable that ENSO episodes tend to occur more frequently in the recent 15 years. (2) An index describing East Asian summer monsoon is well correlated with the SST in the Nino-3 region in preceding autumn in the recent 20 years but is not prior to the period. This means that the El Nino phenomenon exerts more impacts on East Asian summer monsoon recently. (3) The warm phase of PDO in the recent 20 years basically coincides with the increasing trend of the atmospheric circulation in East Asia.展开更多
Ti5553-xFe (x=0.4, 1.2, 2.0, wt.%) alloys have been designed and fabricated through BE (blended element) sintering to investigate the effect of Fe-addition on athermal ω-phase transformation, α-phase evolution and a...Ti5553-xFe (x=0.4, 1.2, 2.0, wt.%) alloys have been designed and fabricated through BE (blended element) sintering to investigate the effect of Fe-addition on athermal ω-phase transformation, α-phase evolution and age hardening behavior. The results show that the formation of athermal ω-phase is fully suppressed in water-quenched specimens when Fe-addition is up to 2 wt.%. The relevant timescales of α formation during initial stages of aging indicate that incubation time increases with Fe-addition. Further aging results in continuous nucleation and growth of α-phase but finer intragranular α lamellae exhibit in Ti5553-2Fe alloy. In addition, the width and extent of grain boundary α-film increase slightly with incremental Fe-addition, especially in furnace cooling condition. Result of Vickers hardness manifests that Fe-addition leads to a strong hardening effect in both solution and aging treatment. The solid solution strengthening is quantitatively estimated by ab initio calculation based on the Labusch?Nabarro model. The evolution of α-precipitate is rationalized by Gibbs free energy. The prominent hardening effect of Ti5553?2Fe alloy is attributed to both large lattice misfit of β-matrix and fine α-precipitate distribution.展开更多
AIM: To isolate and identify the soybean conglycinin peptides that selectively stimulates the growth of bifidobacteria in vitro, and to investigate the effect of soybean conglycinin peptides on intestinal ecosystem i...AIM: To isolate and identify the soybean conglycinin peptides that selectively stimulates the growth of bifidobacteria in vitro, and to investigate the effect of soybean conglycinin peptides on intestinal ecosystem in vivo. METHODS: Soybean conglycinin was purified from soybean seeds by gel filtration (Sepharose-CL-6B). These proteins were submitted to hydrolysis by pepsin. Several growth-stimulating peptides for bifidobacteria were isolated chromatographically from pepsin hydrolysis of soybean conglycinin and identified by means of matrixassisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF-MS). Parallel to in vitro study, in vivo experiments with soybean conglycinin peptides were performed in mice. Ninety male KM mice were randomly assigned into five groups of 16 mice each, and each group was administered for 21d intragastrically with physiological saline (control), conglycinin, pepsin-treated conglycinin (PTC), the most active fraction which isolated from pepsin-treated conglycinin (P2-PTC) and HCl-full hydrolysis of conglycinin (HCl-FHC), respectively. Intestinal microflora were evaluated by standard microbiologic methods and biochemical assays of cecal content samples after treatment. RESULTS: The results showed that the peptides which were isolated from soybean conglycinin could stimulate the growth of bifidobacteria in vitro, and the molecular mass of purified peptides with MALDI-TOF-MS ranged from 693.32 to 1829.55. Compared with control group, in vivo experiments showed that P2-PTC group decreased cecal pH (7.08±0.08 vs7.21±0.09, P〈0.05) and enterococcicounts (5.38±0.26 log10CFU/g vs 5.78±0.19 log10CFU/g, P〈0.05), significantly increased sIgA level (172.08±35.40 ng/g vs 118.27±33.93 ng/g, P〈0.01) and β-galactosidase activity (1.28±0.23 U/g vs 1.82±0.58 U/g, P〈0.05) CONCLUSION: The results have shown that conglycinin is good source for enzyme-mediated production of peptides which stimulate the growth of bifidobacteria. These peptides are inactive within the sequence of the parent protein but can be released during enzymatic hydrolysis, and in vivo experiments demonstrate that conglycinin peptides may be beneficial for improving gastrointestinal health.展开更多
This study examined the effects of salinity on embryonic development, survival, and growth of the Hong Kong oyster Crassostrea hongkongensis. The embryos, larvae, and juveniles of C. hongkongensis were held in artific...This study examined the effects of salinity on embryonic development, survival, and growth of the Hong Kong oyster Crassostrea hongkongensis. The embryos, larvae, and juveniles of C. hongkongensis were held in artificial seawater at three different salinities(low, 15; medium, 23; and high, 30) to determine the optimum hatchery and nursery conditions for mass production of the seeds. Results showed that the percentage production of straight-hinged larvae from fertilized eggs was significantly lower at the high salinity than at the low- and medium-salinities(P < 0.05). The survival rates of larvae and juveniles differed significantly among the three salinity trials, with the highest survival rate observed at the low salinity(P < 0.05). The shell height of larvae was significantly larger at the low salinity than at the high and medium salinities from days 9 to 15(P < 0.05), whereas that of juveniles was significantly larger at the low salinity than at the high and medium salinities on day 70(P < 0.05). These results indicate that the larvae and juveniles of C. hongkongensis are tolerant to a wide range of salinities(15 to 30), but show better growth and survival at relatively low salinities. Thus, it is recommended to use relatively low salinities in hatchery and nursery systems for improved yields of C. hongkongensis.展开更多
Acromegaly is an insidious endocrine disease character- ized by chronic elevation of growth hormone (GH) and insulin-like growth factor-1 (IGF-1).Ell Persistent excess se- cretion of GH and IGF-1 damages both card...Acromegaly is an insidious endocrine disease character- ized by chronic elevation of growth hormone (GH) and insulin-like growth factor-1 (IGF-1).Ell Persistent excess se- cretion of GH and IGF-1 damages both cardiac structure and function, leading to acromegalic cardiomyopathy, which is one of the most common causes of increased mortality in acromegaly and can result in an average of 10-year reduction in life expectancy.I2'31 In patients with acromegaly, approximately 3% have been reported having a unique cardiomyopathy characterized by biventricular hypertrophy, myocardial necrosis, lymphocytic infiltration, interstitialfibrosis.展开更多
AIM:To determine the expression and clinical significance of transcriptional intermediary factor 1 gamma (TIF1γ),Smad4 and transforming growth factor-beta (TGFβR) across a spectrum representing colorectal cancer (CR...AIM:To determine the expression and clinical significance of transcriptional intermediary factor 1 gamma (TIF1γ),Smad4 and transforming growth factor-beta (TGFβR) across a spectrum representing colorectal cancer (CRC) development.METHODS:Tissue microarrays were prepared from archival paraffin embedded tissue,including 51 colorectal carcinomas,25 tubular adenomas (TA) and 26 HPs,each with matched normal colonic epithelium.Immunohistochemistry was performed using antibodies against TIF1γ,Smad4 and TGFβ RⅡ.The levels of expression were scored semi-quantitatively (score 0-3 or loss and retention for Smad4).RESULTS:Overexpression of TIF1γ was detected in 5/26 (19%) HP;however,it was seen in a significantly higher proportion of neoplasms,15/25 (60%) TAs and 24/51 (47%) CRCs (P<0.05).Normal colonic mucosa,HP,and TAs showed strong Smad4 expression,while its expression was absent in 22/51 (43%) CRCs.Over-expression of TGFβ RⅡ was more commonly seen in neoplasms,13/25 (52%) TAs and 29/51 (57%) CRCs compared to 9/26 (35%) HP (P<0.05).Furthermore,there was a correlation between TIF1γ overexpression and Smad4 loss in CRC (Kendall tau rank correlation value=0.35,P<0.05).The levels of TIF1γ overexpression were significantly higher in stage Ⅲ than in stage Ⅰ and Ⅱ CRC (P<0.05).CONCLUSION:The findings suggest that over-expression of TIF1γ occurs in early stages of colorectal carcinogenesis,is inversely related with Smad4 loss,and may be a prognostic indicator for poor outcome.展开更多
This paper shows that there are two different phases in economics. These are the primal and dual problems. In the primal problem phase, capital expenditures of private corporations grow, creating an impetus towards th...This paper shows that there are two different phases in economics. These are the primal and dual problems. In the primal problem phase, capital expenditures of private corporations grow, creating an impetus towards the maximization of profits. In this case, as Adam Smith once wrote, the "invisible hand of God" works to lead the economy to a significant growth. This paper defines the concept of economic growth, bubble economy and destruction of bubble economy. And this paper describes why bubble economy occurs and crashes. In the process, this paper shows that primal economy exists before bubble economy and dual economy exists after destruction of bubble economy.展开更多
Planting date is a critical component of soybean [Glycine max (L.) Merr.] production, under dry land conditions in the Southeastern Coastal Plain. The objectives of this study were to 1. Evaluate the effect of plant...Planting date is a critical component of soybean [Glycine max (L.) Merr.] production, under dry land conditions in the Southeastern Coastal Plain. The objectives of this study were to 1. Evaluate the effect of planting date on plant leaf area index (LAI) and normalized difference vegetation index (NDVI) at 60 and 90 days after planting (DAP), plant height and grain yield, and 2. Determine the optimum planting period by integrating the responses from vegetation growth to yield for soybean maturity group (MG) IV-VIII under dry land conditions in the Southeastern Coastal Plain. Planting dates were scheduled about 14-days intervals from late April to mid-July (2008) or late July (2009). Greatest grain yield for MG IV was obtained from planting in around mid-May in both years. The yield was greater for MG V planted in May and greater for MG VI-VIII planted in late April and May, but started to decline for planting in early June. Plant LAI and NDVI at 60 DAP were affected by both planting date and precipitation, but were poorly correlated with grain yield. However, plant LAI and NDVI were well correlated with yield and were greater for May planting dates at 90 DAP. These indiccs declined for soybean planted after May. Mature plant height decreased more rapidly with delayed planting. These results indicate that plant growth and yield decreased after May planting. Optimum planting period for all MGs was early to mid-May.展开更多
The turbidity maximum zone(TMZ) is one of the most important regions in an estuary.However,the high concentration of suspended material makes it difficult to measure the partial pressure of CO_2(pCO_2) in these region...The turbidity maximum zone(TMZ) is one of the most important regions in an estuary.However,the high concentration of suspended material makes it difficult to measure the partial pressure of CO_2(pCO_2) in these regions.Therefore,very little data is available on the pCO_2 levels in TMZs.To relatively accurately evaluate the CO_2 flux in an example estuary,we studied the TMZ and surrounding area in the Changjiang(Yangtze) River estuary.From seasonal cruises during February,August,November 2010,and May 2012,the pCO_2 in the TMZ and surrounding area was calculated from pH and total alkalinity(TA)measured in situ,from which the CO_2 flux was calculated.Overall,the TMZ and surrounding area acted as a source of atmosphere CO_2 in February and November,and as a sink in May and August.The average FCO_2was-9,-16,5,and 5 mmol/(m^2·d) in May,August,November,and February,respectively.The TMZ's role as a source or sink of atmosphere CO_2 was quite different to the outer estuary.In the TMZ and surrounding area,suspended matter,phytoplankton,and pH were the main factors controlling the FCO_2,but here the influence of temperature,salinity,and total alkalinity on the FCO_2 was weak.Organic carbon decomposition in suspended matter was the main reason for the region acting as a CO_2 source in winter,and phytoplankton production was the main reason the region was a CO_2 sink in summer.展开更多
AIM:To compare rifaximin and insulin-like growth factor(IGF)-1 treatment of hyperammonemia and brain edema in cirrhotic rats with portal occlusion.METHODS:Rats with CCl4-induced cirrhosis with ascites plus portal vein...AIM:To compare rifaximin and insulin-like growth factor(IGF)-1 treatment of hyperammonemia and brain edema in cirrhotic rats with portal occlusion.METHODS:Rats with CCl4-induced cirrhosis with ascites plus portal vein occlusion and controls were randomized into six groups:Cirrhosis;Cirrhosis + IGF-1;Cirrhosis + rifaximin;Controls;Controls + IGF-1;and Controls + rifaximin.An oral glutamine-challenge test was performed,and plasma and cerebral ammonia,glucose,bilirubin,transaminases,endotoxemia,brain water content and ileocecal cultures were measured and liver histology was assessed.RESULTS:Rifaximin treatment significantly reduced bacterial overgrowth and endotoxemia compared with cirrhosis groups,and improved some liver function parameters(bilirubin,alanine aminotransferase and aspartate aminotransferase).These effects were associated with a significant reduction in cerebral water content.Blood and cerebral ammonia levels,and area-underthe-curve values for oral glutamine-challenge tests were similar in rifaximin-treated cirrhotic rats and control group animals.By contrast,IGF-1 administration failed to improve most alterations observed in cirrhosis.CONCLUSION:By reducing gut bacterial overgrowth,only rifaximin was capable of normalizing plasma and brain ammonia and thereby abolishing low-grade brain edema,alterations associated with hepatic encephalopathy.展开更多
The well-known Three Gorges Dam(TGD) within the Yangtze catchment launched its operation in 2003. The effect of the TGD operation on the sediment size on the East China Sea shelf is rarely known. High resolution(0.5 c...The well-known Three Gorges Dam(TGD) within the Yangtze catchment launched its operation in 2003. The effect of the TGD operation on the sediment size on the East China Sea shelf is rarely known. High resolution(0.5 cm sampling) grain size analysis and 137 Cs and 210 Pb dating of the DH8-1 core were conducted with core collected from the distal part of a main sink for the modern Yangtze sediment entering the sea, the Min-Zhe Coastal Mud Deposits(MZCMD) on the inner East China Sea shelf. The 137 Cs dating results show that the core DH8-1 formed during 1946–2012 with a mean deposition rate of 0.65 cm yr^(-1), indicating that the 0.5 cm sampling for grain size analysis in this local area could reflect environmental changes generally on a one-year time scale. The mean grain size of DH8-1 core sediment that deposited after 2003 is significantly larger than that deposited during 1988–2002. After ruling out other possible factors, we infer that the sediment coarsening of DH8-1 core after 2003 is attributed to the TGD operation which causes the erosion of the Yangtze subaqueous delta. Specifically, the TGD operation significantly intensifies the declining trend of the Yangtze sediment loads to the sea despite no decreased water discharge, which results in extensive erosion of the Yangtze subaqueous delta. The relatively coarse sediment of the subaqueous delta is eroded and resuspended by ocean dynamics and then transported by coastal current, finally depositing on the MZCMD area. In addition, the general sediment fining of core DH8-1 that deposited during 1988–2002, comparing with 1946–1987, is mainly caused by dam construction and soil and water conservation within the Yangtze catchment. Our findings are helpful for better understanding the effects of such a huge dam as the TGD on a sediment sink like the MZCMD of such a large river as the Yangtze River.展开更多
The decadal variation of the intensity of the interannual opposite connection (seesaw) between the Somali and Australian cross-equatorial flows (CEFs) is investigated. During the period prior to the mid-1960s, and...The decadal variation of the intensity of the interannual opposite connection (seesaw) between the Somali and Australian cross-equatorial flows (CEFs) is investigated. During the period prior to the mid-1960s, and after the early-2000s, the intensity of the interannual seesaw connection is significantly weaker relative to the period between. Such interdecadal shifts in the interannual seesaw intensity bear a resemblance to the decadal shift in ENSO's strength, and can be further attributed to the phase transition of the Atlantic Multidecadal Oscillation (AMO). When the AMO is in a positive phase, the ENSO amplitude reduces and the seesaw strength becomes weakened, and vice versa.The historical simulation outputs of the CMIP5 models are used to verify the connection, and a similar result was obtained. Thus, the notion that the intensity of the interannual opposite connection (seesaw) between the CEFs is modulated by the AMO is robust.展开更多
Television as one of the popular culture media plays an important role in the development of students' personality and knowledge because it provides countless information and entertainment that can enhance their know...Television as one of the popular culture media plays an important role in the development of students' personality and knowledge because it provides countless information and entertainment that can enhance their knowledge as the viewers. This study was conducted to give an idea whether television viewing and parental attention can assist students to take a decision of choosing major at the senior high school. This study used descriptive method which analyzed the correlation among television viewing, parental attention, and the students' motivation to choose a major. The sample of this study consisted of 100 students of the state senior high school in Malang, East Java. The finding shows that there is no correlation among television viewing, parental attention, and the students' motivation to choose major at the senior high school. In other words, the possibility of choosing the major can be attributed to some other factors such as interest, talent, aspiration, and other expectation to achieve their goals展开更多
Irrigation with reclaimed water is an important way to deal with water shortage of agricultural production and solve the problem of sewage pollution. The response of crop antioxidant enzyme system is an early-warning ...Irrigation with reclaimed water is an important way to deal with water shortage of agricultural production and solve the problem of sewage pollution. The response of crop antioxidant enzyme system is an early-warning indicator of environmental factors changes. Compared with raw wastewater and used fresh water as controls, this research studied peroxides (POD), superoxide dismutase (SOD) activities and malondialdehyde (MDA) content in leaves from maize (Zea mays L.) and soybean (Phaseolus vulgaris L.) with pot culture under irrigating with reclaimed water which with secondary and third treatment. The results showed that secondary reclaimed water had some adverse effects on antioxidant system of maize in seedling stage, and the influence decreased in later stage of maize; effect of the third reclaimed water on antioxidant system of maize was not significant. Irrigation with reclaimed water has little influence on antioxidant system of soybean in seedling and reaping stage, but it could bring some oxidative stress in blossom stage. As a result, irrigating maize with second or third reclaimed water is safe to the growth of maize and soybean, but it is suggested that second reclaimed water should not be used in seedling stage of maize and reclaimed water should not be used in the second stage of soybean.展开更多
The anthropogenic CO column content in the atmosphere is derived from measurements with infrared grating spectrometers in Beijing,China,and Moscow,Russia,during 1992–2012.Some specific variation characteristics and l...The anthropogenic CO column content in the atmosphere is derived from measurements with infrared grating spectrometers in Beijing,China,and Moscow,Russia,during 1992–2012.Some specific variation characteristics and long-term variation trends of the CO column content in the atmosphere in these regions are discussed.An evident variation trend of anthropogenic CO in the atmosphere for the Beijing region is not observed during 1992–2012,while for the Moscow region,it decreases yearly by about 1.4% for the same period.High CO concentrations appear quite frequently in Beijing,but much less frequently in Moscow,except during the natural fire events in summer 2010.From back trajectory analysis,the high CO concentration observed in Beijing can be attributed to the intensive CO emission sources in its surrounding areas.展开更多
基金Project(U1037601) supported by the National Natural Science Foundation of China
文摘The effect of Ru on γ' precipitation behavior and evolution in single crystal superalloys with different Ru contents were investigated by scanning electron microscopy with energy dispersive spectroscopy,3D atomic probing,differential scanning calorimetry.The results show that the solvus of the γ' phase decreases gradually with increasing Ru content in the alloys by casting or by the same solution and aging treatments,the alloy with a larger Ru content yields a smaller γ' phase.The addition of Ru increases the growth rate and coarsening rate of the γ' phase.Ru mainly distributes in the γ phase,which causes more Re and Mo partition into the γ' phase,increasing the absolute value of mismatch and the rafting rate of the γ' phase.
文摘The tidal current duration (TCD) and velocity (TCV) and suspended sediment concentration (SSC) were measured in the dry season in December, 2011 and in the flood season in June, 2012 at the upper part of the North Channel of Changjiang Estuary. They were assimilated with the measured data in 2003, 2004, 2006 and 2007, using the tidal range's proportion conversion. Variations in TCD and TCV, preferential flow and SSC have been calculated. Influences of typical engineering projects such as Qingcaosha fresh water reservoir, Yangtze River Bridge, and land reclamation on the ebb and flood TCD, TCV and SSC in the North Channel for the last 10 years are discussed. The results show that: (1) currently, in the upper part of North Channel, the ebb tide dominates; after the construction of the typical projects, ebb TCD and TCV tends to be larger and the vertical average ebb and flood SSC decrease during the flood season while SSC increases during the dry season; (2) changes in the vertical average TCV are mainly contributed by seasonal runoff variation during the flood season, which is larger in the flood season than that in the dry season; the controlling parameters of increasing ebb TCD and TCV are those large-scale engineering projects in the North Channel; variation in SSC may result mainly from the reduction of basin annual sediment loads, large-scale nearshore projects and so on.
基金Project (192450/I30) supported by the Norwegian Research Council under the Strategic University Program
文摘With the help of FESEM, high resolution electron backscatter diffraction can investigate the grains/subgrains as small as a few tens of nanometers with a good angular resolution (~0.5°). Fast development of EBSD speed (up to 1100 patterns per second) contributes that the number of published articles related to EBSD has been increasing sharply year by year. This paper reviews the sample preparation, parameters optimization and analysis of EBSD technique, emphasizing on the investigation of ultrafine grained and nanostructured materials processed by severe plastic deformation (SPD). Detailed and practical parameters of the electropolishing, silica polishing and ion milling have been summarized. It is shown that ion milling is a real universal and promising polishing method for EBSD preparation of almost all materials. There exists a maximum value of indexed points as a function of step size. The optimum step size depends on the magnification and the board resolution/electronic step size. Grains/subgrains and texture, and grain boundary structure are readily obtained by EBSD. Strain and stored energy may be analyzed by EBSD.
基金Supported by the Knowledge Innovation Program of Chinese Academy of Sciences (No. KZCX2-YW-Q11-02)the Strategic Priority Research Program of Chinese Academy of Sciences (No. XDA05090404)the National Natural Science Foundation of China (No. 41106026)
文摘Based on observed temperature data since the 1950s, long-term variability of the summer sharp thermocline in the Yellow Sea Cold Water Mass (YSCWM) and East China Sea Cold Eddy (ECSCE) areas is examined. Relationships between the thermocline and atmospheric and oceanic forcing were investigated using multiyear wind, Kuroshio discharge and air temperature data. Results show that: 1) In the YSCWM area, thermocline strength shows about 4-year and 16-year period oscillations. There is high correlation between summer thermocline strength and local atmospheric temperature in summer and the previous winter; 2) In the ECSCE area, interannual oscillation of thermocline strength with about a 4-year period (stronger in El Nifio years) is strongly correlated with that of local wind stress. A transition from weak to strong thermocline during the mid 1970s is consistent with a 1976/1977 climate shift and Kuroshio volume transport; 3) Long-term changes of the thermocline in both regions are mainly determined by deep layer water, especially on the decadal timescale. However, surface water can modify the thermocline on an interannual timescale in the YSCWM area.
基金Research Fund for Tropical Oceans Project 973 of the Ministry of Science and Technology(2004CB418300) No. 2002DIB20067 from the Ministry of Science and Technology.
文摘This study examined the rainfall around the middle and lower reaches of the Yangtze River and related atmospheric circulation by using NCEP reanalysis data. The purpose of this study is to analyze their decadal variation and the relationship among rainfall, atmospheric circulation around East Asia and the ENSO episodes. Current results are presented as follows: (1) Very clear increasing trend of the rainfall around the middle and low reaches of the Yangtze River during the Meiyu period and June to July is found in the recent 15 years. Meanwhile, the geopotential height at 500 hPa around the Okhotsk Sea also holds similar increasing trend. It is noticeable that ENSO episodes tend to occur more frequently in the recent 15 years. (2) An index describing East Asian summer monsoon is well correlated with the SST in the Nino-3 region in preceding autumn in the recent 20 years but is not prior to the period. This means that the El Nino phenomenon exerts more impacts on East Asian summer monsoon recently. (3) The warm phase of PDO in the recent 20 years basically coincides with the increasing trend of the atmospheric circulation in East Asia.
基金Projects(51671158,51871176,51621063)supported by the National Natural Science Foundation of ChinaProject(2014CB644003)supported by the National Basic Research Program of China+1 种基金Project(PB2018008)supported by the 111 Project 2.0,ChinaProject(2018JM5098)supported by the Natural Science Basic Research Plan in Shaanxi Province of China
文摘Ti5553-xFe (x=0.4, 1.2, 2.0, wt.%) alloys have been designed and fabricated through BE (blended element) sintering to investigate the effect of Fe-addition on athermal ω-phase transformation, α-phase evolution and age hardening behavior. The results show that the formation of athermal ω-phase is fully suppressed in water-quenched specimens when Fe-addition is up to 2 wt.%. The relevant timescales of α formation during initial stages of aging indicate that incubation time increases with Fe-addition. Further aging results in continuous nucleation and growth of α-phase but finer intragranular α lamellae exhibit in Ti5553-2Fe alloy. In addition, the width and extent of grain boundary α-film increase slightly with incremental Fe-addition, especially in furnace cooling condition. Result of Vickers hardness manifests that Fe-addition leads to a strong hardening effect in both solution and aging treatment. The solid solution strengthening is quantitatively estimated by ab initio calculation based on the Labusch?Nabarro model. The evolution of α-precipitate is rationalized by Gibbs free energy. The prominent hardening effect of Ti5553?2Fe alloy is attributed to both large lattice misfit of β-matrix and fine α-precipitate distribution.
基金Supported by the National Key Basic Research Development Program of China, 973 Program, No. 2004CB117505
文摘AIM: To isolate and identify the soybean conglycinin peptides that selectively stimulates the growth of bifidobacteria in vitro, and to investigate the effect of soybean conglycinin peptides on intestinal ecosystem in vivo. METHODS: Soybean conglycinin was purified from soybean seeds by gel filtration (Sepharose-CL-6B). These proteins were submitted to hydrolysis by pepsin. Several growth-stimulating peptides for bifidobacteria were isolated chromatographically from pepsin hydrolysis of soybean conglycinin and identified by means of matrixassisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF-MS). Parallel to in vitro study, in vivo experiments with soybean conglycinin peptides were performed in mice. Ninety male KM mice were randomly assigned into five groups of 16 mice each, and each group was administered for 21d intragastrically with physiological saline (control), conglycinin, pepsin-treated conglycinin (PTC), the most active fraction which isolated from pepsin-treated conglycinin (P2-PTC) and HCl-full hydrolysis of conglycinin (HCl-FHC), respectively. Intestinal microflora were evaluated by standard microbiologic methods and biochemical assays of cecal content samples after treatment. RESULTS: The results showed that the peptides which were isolated from soybean conglycinin could stimulate the growth of bifidobacteria in vitro, and the molecular mass of purified peptides with MALDI-TOF-MS ranged from 693.32 to 1829.55. Compared with control group, in vivo experiments showed that P2-PTC group decreased cecal pH (7.08±0.08 vs7.21±0.09, P〈0.05) and enterococcicounts (5.38±0.26 log10CFU/g vs 5.78±0.19 log10CFU/g, P〈0.05), significantly increased sIgA level (172.08±35.40 ng/g vs 118.27±33.93 ng/g, P〈0.01) and β-galactosidase activity (1.28±0.23 U/g vs 1.82±0.58 U/g, P〈0.05) CONCLUSION: The results have shown that conglycinin is good source for enzyme-mediated production of peptides which stimulate the growth of bifidobacteria. These peptides are inactive within the sequence of the parent protein but can be released during enzymatic hydrolysis, and in vivo experiments demonstrate that conglycinin peptides may be beneficial for improving gastrointestinal health.
基金supported by grants from the National Natural Science Foundation of China (31172403)the National Basic Research Program of China (2010CB126406)
文摘This study examined the effects of salinity on embryonic development, survival, and growth of the Hong Kong oyster Crassostrea hongkongensis. The embryos, larvae, and juveniles of C. hongkongensis were held in artificial seawater at three different salinities(low, 15; medium, 23; and high, 30) to determine the optimum hatchery and nursery conditions for mass production of the seeds. Results showed that the percentage production of straight-hinged larvae from fertilized eggs was significantly lower at the high salinity than at the low- and medium-salinities(P < 0.05). The survival rates of larvae and juveniles differed significantly among the three salinity trials, with the highest survival rate observed at the low salinity(P < 0.05). The shell height of larvae was significantly larger at the low salinity than at the high and medium salinities from days 9 to 15(P < 0.05), whereas that of juveniles was significantly larger at the low salinity than at the high and medium salinities on day 70(P < 0.05). These results indicate that the larvae and juveniles of C. hongkongensis are tolerant to a wide range of salinities(15 to 30), but show better growth and survival at relatively low salinities. Thus, it is recommended to use relatively low salinities in hatchery and nursery systems for improved yields of C. hongkongensis.
文摘Acromegaly is an insidious endocrine disease character- ized by chronic elevation of growth hormone (GH) and insulin-like growth factor-1 (IGF-1).Ell Persistent excess se- cretion of GH and IGF-1 damages both cardiac structure and function, leading to acromegalic cardiomyopathy, which is one of the most common causes of increased mortality in acromegaly and can result in an average of 10-year reduction in life expectancy.I2'31 In patients with acromegaly, approximately 3% have been reported having a unique cardiomyopathy characterized by biventricular hypertrophy, myocardial necrosis, lymphocytic infiltration, interstitialfibrosis.
基金Supported by Department of Pathology Research Fund,NYU School of Medicine,New York,NY 10016,United States
文摘AIM:To determine the expression and clinical significance of transcriptional intermediary factor 1 gamma (TIF1γ),Smad4 and transforming growth factor-beta (TGFβR) across a spectrum representing colorectal cancer (CRC) development.METHODS:Tissue microarrays were prepared from archival paraffin embedded tissue,including 51 colorectal carcinomas,25 tubular adenomas (TA) and 26 HPs,each with matched normal colonic epithelium.Immunohistochemistry was performed using antibodies against TIF1γ,Smad4 and TGFβ RⅡ.The levels of expression were scored semi-quantitatively (score 0-3 or loss and retention for Smad4).RESULTS:Overexpression of TIF1γ was detected in 5/26 (19%) HP;however,it was seen in a significantly higher proportion of neoplasms,15/25 (60%) TAs and 24/51 (47%) CRCs (P<0.05).Normal colonic mucosa,HP,and TAs showed strong Smad4 expression,while its expression was absent in 22/51 (43%) CRCs.Over-expression of TGFβ RⅡ was more commonly seen in neoplasms,13/25 (52%) TAs and 29/51 (57%) CRCs compared to 9/26 (35%) HP (P<0.05).Furthermore,there was a correlation between TIF1γ overexpression and Smad4 loss in CRC (Kendall tau rank correlation value=0.35,P<0.05).The levels of TIF1γ overexpression were significantly higher in stage Ⅲ than in stage Ⅰ and Ⅱ CRC (P<0.05).CONCLUSION:The findings suggest that over-expression of TIF1γ occurs in early stages of colorectal carcinogenesis,is inversely related with Smad4 loss,and may be a prognostic indicator for poor outcome.
文摘This paper shows that there are two different phases in economics. These are the primal and dual problems. In the primal problem phase, capital expenditures of private corporations grow, creating an impetus towards the maximization of profits. In this case, as Adam Smith once wrote, the "invisible hand of God" works to lead the economy to a significant growth. This paper defines the concept of economic growth, bubble economy and destruction of bubble economy. And this paper describes why bubble economy occurs and crashes. In the process, this paper shows that primal economy exists before bubble economy and dual economy exists after destruction of bubble economy.
文摘Planting date is a critical component of soybean [Glycine max (L.) Merr.] production, under dry land conditions in the Southeastern Coastal Plain. The objectives of this study were to 1. Evaluate the effect of planting date on plant leaf area index (LAI) and normalized difference vegetation index (NDVI) at 60 and 90 days after planting (DAP), plant height and grain yield, and 2. Determine the optimum planting period by integrating the responses from vegetation growth to yield for soybean maturity group (MG) IV-VIII under dry land conditions in the Southeastern Coastal Plain. Planting dates were scheduled about 14-days intervals from late April to mid-July (2008) or late July (2009). Greatest grain yield for MG IV was obtained from planting in around mid-May in both years. The yield was greater for MG V planted in May and greater for MG VI-VIII planted in late April and May, but started to decline for planting in early June. Plant LAI and NDVI at 60 DAP were affected by both planting date and precipitation, but were poorly correlated with grain yield. However, plant LAI and NDVI were well correlated with yield and were greater for May planting dates at 90 DAP. These indiccs declined for soybean planted after May. Mature plant height decreased more rapidly with delayed planting. These results indicate that plant growth and yield decreased after May planting. Optimum planting period for all MGs was early to mid-May.
基金Supported by the Strategic Priority Research Program of Chinese Academy of Sciences(No.XDA05030402)the National Natural Science Foundation of China(Nos.U1406403,41121064,41376092)the Public Science and Technology Research Funds Projects of Ocean(No.200905012-9)
文摘The turbidity maximum zone(TMZ) is one of the most important regions in an estuary.However,the high concentration of suspended material makes it difficult to measure the partial pressure of CO_2(pCO_2) in these regions.Therefore,very little data is available on the pCO_2 levels in TMZs.To relatively accurately evaluate the CO_2 flux in an example estuary,we studied the TMZ and surrounding area in the Changjiang(Yangtze) River estuary.From seasonal cruises during February,August,November 2010,and May 2012,the pCO_2 in the TMZ and surrounding area was calculated from pH and total alkalinity(TA)measured in situ,from which the CO_2 flux was calculated.Overall,the TMZ and surrounding area acted as a source of atmosphere CO_2 in February and November,and as a sink in May and August.The average FCO_2was-9,-16,5,and 5 mmol/(m^2·d) in May,August,November,and February,respectively.The TMZ's role as a source or sink of atmosphere CO_2 was quite different to the outer estuary.In the TMZ and surrounding area,suspended matter,phytoplankton,and pH were the main factors controlling the FCO_2,but here the influence of temperature,salinity,and total alkalinity on the FCO_2 was weak.Organic carbon decomposition in suspended matter was the main reason for the region acting as a CO_2 source in winter,and phytoplankton production was the main reason the region was a CO_2 sink in summer.
基金Supported by A grant from the Instituto de Salud CarlosTM,PI051371,PI080809
文摘AIM:To compare rifaximin and insulin-like growth factor(IGF)-1 treatment of hyperammonemia and brain edema in cirrhotic rats with portal occlusion.METHODS:Rats with CCl4-induced cirrhosis with ascites plus portal vein occlusion and controls were randomized into six groups:Cirrhosis;Cirrhosis + IGF-1;Cirrhosis + rifaximin;Controls;Controls + IGF-1;and Controls + rifaximin.An oral glutamine-challenge test was performed,and plasma and cerebral ammonia,glucose,bilirubin,transaminases,endotoxemia,brain water content and ileocecal cultures were measured and liver histology was assessed.RESULTS:Rifaximin treatment significantly reduced bacterial overgrowth and endotoxemia compared with cirrhosis groups,and improved some liver function parameters(bilirubin,alanine aminotransferase and aspartate aminotransferase).These effects were associated with a significant reduction in cerebral water content.Blood and cerebral ammonia levels,and area-underthe-curve values for oral glutamine-challenge tests were similar in rifaximin-treated cirrhotic rats and control group animals.By contrast,IGF-1 administration failed to improve most alterations observed in cirrhosis.CONCLUSION:By reducing gut bacterial overgrowth,only rifaximin was capable of normalizing plasma and brain ammonia and thereby abolishing low-grade brain edema,alterations associated with hepatic encephalopathy.
基金the National Natural Science Foundation of China for its financial support (Nos. 41376052, 41030856, 40906024)
文摘The well-known Three Gorges Dam(TGD) within the Yangtze catchment launched its operation in 2003. The effect of the TGD operation on the sediment size on the East China Sea shelf is rarely known. High resolution(0.5 cm sampling) grain size analysis and 137 Cs and 210 Pb dating of the DH8-1 core were conducted with core collected from the distal part of a main sink for the modern Yangtze sediment entering the sea, the Min-Zhe Coastal Mud Deposits(MZCMD) on the inner East China Sea shelf. The 137 Cs dating results show that the core DH8-1 formed during 1946–2012 with a mean deposition rate of 0.65 cm yr^(-1), indicating that the 0.5 cm sampling for grain size analysis in this local area could reflect environmental changes generally on a one-year time scale. The mean grain size of DH8-1 core sediment that deposited after 2003 is significantly larger than that deposited during 1988–2002. After ruling out other possible factors, we infer that the sediment coarsening of DH8-1 core after 2003 is attributed to the TGD operation which causes the erosion of the Yangtze subaqueous delta. Specifically, the TGD operation significantly intensifies the declining trend of the Yangtze sediment loads to the sea despite no decreased water discharge, which results in extensive erosion of the Yangtze subaqueous delta. The relatively coarse sediment of the subaqueous delta is eroded and resuspended by ocean dynamics and then transported by coastal current, finally depositing on the MZCMD area. In addition, the general sediment fining of core DH8-1 that deposited during 1988–2002, comparing with 1946–1987, is mainly caused by dam construction and soil and water conservation within the Yangtze catchment. Our findings are helpful for better understanding the effects of such a huge dam as the TGD on a sediment sink like the MZCMD of such a large river as the Yangtze River.
基金supported by the National Key Basic Research Program of China[grant number 973 Program,2015CB453202]the National Natural Science Foundation of China[grant number 41375085],[grant number 41421004]
文摘The decadal variation of the intensity of the interannual opposite connection (seesaw) between the Somali and Australian cross-equatorial flows (CEFs) is investigated. During the period prior to the mid-1960s, and after the early-2000s, the intensity of the interannual seesaw connection is significantly weaker relative to the period between. Such interdecadal shifts in the interannual seesaw intensity bear a resemblance to the decadal shift in ENSO's strength, and can be further attributed to the phase transition of the Atlantic Multidecadal Oscillation (AMO). When the AMO is in a positive phase, the ENSO amplitude reduces and the seesaw strength becomes weakened, and vice versa.The historical simulation outputs of the CMIP5 models are used to verify the connection, and a similar result was obtained. Thus, the notion that the intensity of the interannual opposite connection (seesaw) between the CEFs is modulated by the AMO is robust.
文摘Television as one of the popular culture media plays an important role in the development of students' personality and knowledge because it provides countless information and entertainment that can enhance their knowledge as the viewers. This study was conducted to give an idea whether television viewing and parental attention can assist students to take a decision of choosing major at the senior high school. This study used descriptive method which analyzed the correlation among television viewing, parental attention, and the students' motivation to choose a major. The sample of this study consisted of 100 students of the state senior high school in Malang, East Java. The finding shows that there is no correlation among television viewing, parental attention, and the students' motivation to choose major at the senior high school. In other words, the possibility of choosing the major can be attributed to some other factors such as interest, talent, aspiration, and other expectation to achieve their goals
基金This paper was supported by the National High Technology Research and Development Program of China (863 Program, No. 2006AA100205) and National Natural Science Foundation of China (No. 50679080)
文摘Irrigation with reclaimed water is an important way to deal with water shortage of agricultural production and solve the problem of sewage pollution. The response of crop antioxidant enzyme system is an early-warning indicator of environmental factors changes. Compared with raw wastewater and used fresh water as controls, this research studied peroxides (POD), superoxide dismutase (SOD) activities and malondialdehyde (MDA) content in leaves from maize (Zea mays L.) and soybean (Phaseolus vulgaris L.) with pot culture under irrigating with reclaimed water which with secondary and third treatment. The results showed that secondary reclaimed water had some adverse effects on antioxidant system of maize in seedling stage, and the influence decreased in later stage of maize; effect of the third reclaimed water on antioxidant system of maize was not significant. Irrigation with reclaimed water has little influence on antioxidant system of soybean in seedling and reaping stage, but it could bring some oxidative stress in blossom stage. As a result, irrigating maize with second or third reclaimed water is safe to the growth of maize and soybean, but it is suggested that second reclaimed water should not be used in seedling stage of maize and reclaimed water should not be used in the second stage of soybean.
基金supported in part by the Strategic Priority Research Program of the Chinese Academy of Sciences (Grant No.XDA05100300)the National Basic Research Program of China (Grant No.2013CB955801)+1 种基金the National Natural Science Foundation of China (Grant No.41175030)the Russian Foundation for Basic Research (Grant No.13-05-00956)
文摘The anthropogenic CO column content in the atmosphere is derived from measurements with infrared grating spectrometers in Beijing,China,and Moscow,Russia,during 1992–2012.Some specific variation characteristics and long-term variation trends of the CO column content in the atmosphere in these regions are discussed.An evident variation trend of anthropogenic CO in the atmosphere for the Beijing region is not observed during 1992–2012,while for the Moscow region,it decreases yearly by about 1.4% for the same period.High CO concentrations appear quite frequently in Beijing,but much less frequently in Moscow,except during the natural fire events in summer 2010.From back trajectory analysis,the high CO concentration observed in Beijing can be attributed to the intensive CO emission sources in its surrounding areas.