信息网络涉烟监管长效协作机制探析

当前,信息网络涉烟监管已成为烟草专卖管理的重点和难点问题。构建和完善信息网络涉烟监管长效协作机制,有力维护国家烟草专卖制度、保护消费者合法权益,显得尤为重要。本文从阐释长效协作机制的涵义及意义入手,分析了机制的现状及问题,提出完善机制建设的措施建议。

rmhTNF-α Combined with Cisplatin Inhibits Proliferation of A549 Cell Line In Vitro

Objective To explore the inhibitory effect of recombinant mutant human tumor necrosis factor-α(rmhTNF-α) in combination with cisplatin on human lung adenocarcinoma cell line A549. Methods Human lung adenocarcinoma cell line A549 was treated with varying concentrations of rmhTNF-α(0.38, 0.75, 1.50, 6.00 and 12.00 IU/ml) or cisplatin(3.91, 7.81, 15.63, 31.25 and 62.50 μg/ml) for 24 hours. Viable cell number was analyzed by using crystal violet staining. The inhibitory rates of A549 cells growth by the two drugs were calculated. For analyzing whether there was a synergistic effect of rmhTNF-α with cisplatin, A549 cells were treated with 0.75 IU/ml rmhTNF-α and increased concentrations of cisplatin. Results rmhTNF-α or cisplatin inhibited the growth of A549 cell lines in a dose-dependent manner. The inhibitory effect of rmhTNF-α combined with cisplatin was significantly greater than cisplatin alone at the same concentration(all P<0.01). Conclusion rmhTNF-α combined with cisplatin might have synergistic inhibitory effect on human lung adenocarcinoma cell line A549.

多措并举 推动婴幼儿早期发展工作高质量深入发展

河北省大名县委、县政府高度重视儿童早期发展工作,将儿童早期发展工作与乡村振兴战略紧密连接,明确全县儿童早期发展总体目标和阶段性任务,建立县委、县政府主导,卫生健康部门牵头,宣传、财政、教育、民政、妇联等有关部门长效协作机制,由大名县妇幼保健院负责具体项目实施并组建儿童早期发展专家组,对全县婴幼儿早期发展工作者进行带教和培训。县委、县政府多次印发有关婴幼儿早期发展工作的文件,明确作为国家项目试点县项目的具体工作措施,为国家项目试点县项目深入开展奠定坚实基础。