[Objective] This study was conducted to investigate effects of different intercropping modes on growth, yields and economic benefit of cassava and peanut in symbiotic period. [Method] With sole cropping of cassava (M...[Objective] This study was conducted to investigate effects of different intercropping modes on growth, yields and economic benefit of cassava and peanut in symbiotic period. [Method] With sole cropping of cassava (M1) and sole cropping of peanut (M2) as control groups, effects of intercropping of cassava with 1 row, 2 rows and 3 rows of peanut (M3, M4 and M5)on crop growth, yields and economic benefit were studied. [Result] Intercropping affected both growth and yields of cassava and peanut. Growth competition existed between cassava and peanut, and plant heights of cassava and peanut changed similarly. In late stages of intercropping, treatments M1, M2 and M5 showed higher plant heights under no nitrogen application, while treatment M3 and M4 exhibited higher plant heights under nitrogen application; intercropping improved leaf temperature, but no obvious law could be observed among different intercropping treatments; and intercropping improved total dry matter amount, which was the highest in M5 in root expanding stage and on the 30th day of the expanding stage, and the highest in M4 on the 60th day of the expanding stage. Intercropping reduced the yield of single plant, but improved the economic benefit of red upland soil; and under no nitrogen application and nitrogen application, cassava yields decreased by 25.35% and 14.55%, respectively, peanut yields decreased by 28.76% and 52.60%, respectively, while economic benefit increased by 72.90% and 56.82%, respectively. [Conclusion] Compared with sole cropping, interplanting cassava with 1 row, 2 rows or 3 rows of peanut could all improve economic benefit, and the economic benefit increased with number of rows of interplanted peanut increasing.展开更多
Remarkable achievements have been made in China's agricultural development since the late 1970s. Nevertheless, deep-rooted problems are arising from inefficient farming practices. From mid- and long-term perspectives...Remarkable achievements have been made in China's agricultural development since the late 1970s. Nevertheless, deep-rooted problems are arising from inefficient farming practices. From mid- and long-term perspectives, migration of China's agricultural labor will slow and large-scale operation of farmland will accelerate. Although grain supply and demand have maintained a tight balance, new potentials still exist in improving grain production. Under the pressures of resource and environmental constraints, advancing the green and efficient transition of agriculture will become a new trend in China's agricultural development. In this context, the treatment of agricultural pollution, supply-side structural reform and innovation of agricultural subsidy policy are of strategic significance to the transition and upgrade of China's agriculture.展开更多
This study was conducted to investigate the effects of different packaging methods on seed germination and vigor under a long-term bank storage condition, selecting suitable packaging materials and methods, and compre...This study was conducted to investigate the effects of different packaging methods on seed germination and vigor under a long-term bank storage condition, selecting suitable packaging materials and methods, and comprehensively estimate changes in seed vigor of seeds stored with different packaging materials. Hibiscus cannabinus L. seeds were stored in aluminium box, seed box, glass bottle, POlyethylene film bag, sack and kraft paper bag as packaging materials in a, long-term bank and tested for their seeds germinability, electrical conductivity and field seedling rate after 31 years. The results showed that the kenaf seeds with an initial germination rate of 88% exhibited the germination rates over 79.7% after being stored in the 6 packaging materials for 31 years, the germination rates of seeds packaged with paper bag and sack and of those sealed in film bag and aluminium box showed significantly decreased germination rates, while the seeds sealed in seed boxes and glass bottles exhibited non-significant decreases in seed germination rate, and their germination rates were still above 85%. Seed box and glass bottle were the packaging materials most suitable for long-term safe storage of kenaf seeds with a safe storage period long than 31 years.展开更多
The changes of physiological and biochemical indices in jujube fruits during the late development were investigated from 6-year-old jujube trees (Zizyphus jujuba Mill. cv. Lingwuchangzao). The results showed that th...The changes of physiological and biochemical indices in jujube fruits during the late development were investigated from 6-year-old jujube trees (Zizyphus jujuba Mill. cv. Lingwuchangzao). The results showed that the flesh firmness decreased slowly from white-green stage to full-red stage, being significantly related with the developmental maturity of jujube fruits negatively, the correlation coefficient reached -0.980 3^**. The contents of ascorbic acid and titratable acid in jujube fruits were significantly related with the developmental process of jujube fruits negatively or positively, the correlation coef- ficients were -0. 973 1^**and + 0. 974 6^ * * , respectively. The contents of soluble solids, total sugar, and sucrose increased with jujube ripening, while the relative sweetness of jujube fruits showed the same variation pattern, the correlation coefficients were 0. 996 6 ^* * , 0. 988 0^** , and 0. 982 8 ^* * , respectively. Before white-green stage during fruit development, the accumulation of monosaccharide was predominant in jujube fruits, following a fast accumulation of sucrose, indicating that the main component of sugars is sucrose at the crisp-ripe stage. Furthermore, the starch content of the flesh reached the peak at about thirty percentage of jujube maturity, being 51,54 mg/100 g.FW. The respiratory rates varied between 10 mg/( kg.h) and CO2 26 mg/( kg.h) after fruit turning red and before softening, indicating a non-climacteric respiratory type.展开更多
The surge in China's local government debt has made various sectors of society pay closer attention to the situation. First of all, four types of debt relations must be clarified: the relationship between asset and ...The surge in China's local government debt has made various sectors of society pay closer attention to the situation. First of all, four types of debt relations must be clarified: the relationship between asset and non-asset debt, the difference between long- term and short-term debt, the difference between debt in the form of bonds and debt in the form of bank loans, and the difference between debt listed in government budgets and other government debt. The development of long-term bonds is a fairly good choice for China to upgrade its consumption structure, accelerate urbanization, transform its economic development patterns, and meanwhile, to alleviate the mismatch between the financial powers of local governments and their administrative responsibilities.展开更多
AIM: To evaluate hepatic recurrence and prognostic factors for survival in patients with surgically resected hilar cholangiocarcinoma in a single institution over the last 13 years. METHODS: From 1994 to 2007, all p...AIM: To evaluate hepatic recurrence and prognostic factors for survival in patients with surgically resected hilar cholangiocarcinoma in a single institution over the last 13 years. METHODS: From 1994 to 2007, all patients with hilar cholangiocarcinoma referred to a surgical clinic were evaluated. Demographic data, tumor characteristics, and outcome were analyzed retrospectively. Outcome was compared in patients who underwent additional liver resection with resection of the tumor. RESULTS: Of the 69 patients submitted to laparotomy for tumor resection, curative resection (Ro resection) was performed in 40 patients, and palliative resection in 29. Thirty-one patients had only duct resection, and 38 patients had combined duct resection with liver resection including 34 total or part caudate lobes. Curative rates with the combined hepatectomy were significantly improved compared with those without additional hepatectomy (27/38 vs 13/31; X^2 = 5.94, P 〈 0.05). Concomitant liver resection was associated with a decreased incidence of initial recurrence in liver one year after surgery (11/38 vs 23/31; X^2 = 13.98, P 〈 0.01). The 3-year survival rate after Ro resection was 30.7% and was 10.5% for palliative resection. R0 resection improved the 3-year survival rate (30.7% vs 10.5%; X^2 = 12.47, P 〈 0.01).CONCLUSION: Hepatectomy, especially including the caudate lobe combined with bile duct resection should be considered standard treatment to cure hilar cholangiocarcinoma.展开更多
The objectives of the present study were to evaluate the yolk-sac and oil globule absorption and point of no return (PNR) ofpikeperch (Sander lucioperca L.) larvae. Artificial propagation ofpikeperch was performed...The objectives of the present study were to evaluate the yolk-sac and oil globule absorption and point of no return (PNR) ofpikeperch (Sander lucioperca L.) larvae. Artificial propagation ofpikeperch was performed at (15±2)℃. Yolk-sac absorption, oil globule absorption, larval growth and the first initial feeding rate were observed to analyze the early growth and to determine the PNR of pikeperch larvae. The total length of newly hatched (0 day after hatching, DAH) pikeperch larvae was (4.25±0.22) mm and the volume of the yolk-sac and the oil globule was (0.30±0.12)mm^3 and (5.14±2.28) 10-2 mm^3 respectively. The yolk-sac and the oil globule were exhausted at 11 DAH and 14 DAH, respectively. Pikeperch larvae began feeding at 8 DAH with an initial feeding rate about 10.0%. From 9 to 14 DAH, the initial feeding rate increased rapidly, and reached its highest (about 82.7%) at 14 DAH. It declined thereafter, 48.9% at 15 DAH and 35.6% at 16 DAH, thus the pikeperch larvae reached PNR by 15-16 DAH. The appropriate first feeding time for the pikeperch larvae is 11-12 DAH, when the initial feeding rate is higher than half of the maximum initial feeding rate.展开更多
AIMTo evaluate complications and management outcomes of retained long-term plastic biliary stents.METHODSEndoscopic plastic biliary stent placement was performed in 802 patients at Yeungnam University Hospital between...AIMTo evaluate complications and management outcomes of retained long-term plastic biliary stents.METHODSEndoscopic plastic biliary stent placement was performed in 802 patients at Yeungnam University Hospital between January 2000 and December 2014. Follow-up loss with a subsequently forgotten stent for more than 12 mo occurred in 38 patients. We retrospectively examined the cause of biliary stent insertion, status of stents, complications associated with biliary stents and management outcomes of long-term plastic biliary stents. Continuous variables were analyzed using the t test. Observed frequencies in subsets of the study population were compared using Fisher’s exact test and χ<sup>2</sup> tests. Statistical significance was defined as P < 0.05 (two-tailed).RESULTSMean age of patients was 73.7 ± 12 years and male-to-female ratio was 2.2:1. Indications of plastic biliary stent insertion were bile duct stones (63.2%, 24/38) and benign bile duct stricture (52.6%, 20/38). Mean duration of retained plastic stent was 22.6 ± 12.2 mo, and in 10 cases (26.3%), stents were retained for more than 24 mo. Common bile duct (CBD) stones or sludge were found in most cases (92.1%, 35/38). The most common complication was acute cholangitis (94.7%, 36/38). Stent removal by endoscopic approach was successfully performed in 92.1% (35/38) of the cases. In 3 cases, an additional plastic stent was inserted alongside the previous stent due to failure of the stent removal. Endoscopic removal of bile duct stones was successful in 73.7% (28/38) of the cases. When patients were divided into two groups by duration of stent placement (12 to 24 mo vs over 24 mo), there were no differences in the development of cholangitis, presence of biliary stones, and success rate of endoscopic removal of stones and biliary stents.CONCLUSIONThe most common complication of retained long-term plastic biliary stents was acute cholangitis associated with CBD stones. Endoscopic management was successfully performed in most cases.展开更多
The insulin-like growth factors Ⅰ and Ⅱ (IGF-Ⅰ and IGF-Ⅱ) are important proteins involved in fish growth and develop- ment. Here, we report the isolation of IGF-Ⅱ and expression analysis of IGFs in turbot Scoph...The insulin-like growth factors Ⅰ and Ⅱ (IGF-Ⅰ and IGF-Ⅱ) are important proteins involved in fish growth and develop- ment. Here, we report the isolation of IGF-Ⅱ and expression analysis of IGFs in turbot Scophthalmus maximus, aiming to clarify their function in embryonic and larval development of fish. The deduced IGF-Ⅱ gene is 808 bp in full length, which encodes a protein of 219 amino acids and is 93% similar with that ofParalichthys olicaceus in amino acid sequence. The tissue abundance and the ex- pression pattern of IGFs in a turbot at early development stages were investigated via reverse transcription-polymer chain reaction. Result showed that the IGF-Ⅰ and IGF-Ⅱ genes were widely expressed in tissues of S. maximus. IGF-Ⅰ was detected in all tissues ex- cept intestines with the highest level in liver, while IGF-Ⅱ transcript presented in all tissues except muscle. At the stages of embry- onic and larval development, the mRNA levels of IGFs sharply increased from the stage of unfertilized egg to post larva, followed by a decrease with larval development. However, there was an increase in IGF-Ⅰ at the embryonic stage and IGF-Ⅱ at the gastrula stage, respectively. These results suggested that IGFs play important roles in cell growth and division of the turbot. Our study provides reference data for further investigation of growth regulation in turbot, which can guarantee better understanding of the physiological role that IGFs play in fish.展开更多
The length-weight relationship and allometric growth patterns of hatchery-reared Chinese loach, Paramisgurnus dabryanus(Dabry de Thiersant, 1872), were determined from hatching to 60 days after hatching. A best power ...The length-weight relationship and allometric growth patterns of hatchery-reared Chinese loach, Paramisgurnus dabryanus(Dabry de Thiersant, 1872), were determined from hatching to 60 days after hatching. A best power model was estimated for the length-weight relationship during the early life stages. Positive allometric growth for the head segment, trunk length, tail length and eye diameter was also found in the early life stages, while body depth, tail depth, tail fi n length, pectoral fi n length and barbel length displayed a negative coeffi cient. During the subsequent early developmental stage, the growth coeffi cients showed a clear and common tendency towards isometry for all measured body ratios. The allometric growth changes in Chinese loach during the early stage are possibly the result of selective organogenesis directed towards survival priorities.展开更多
Crohn's disease (CD) is a chronic relapsing and remitting autoinflammatory disorder of the gastrointestinal tract that has many intestinal and extraintestinal complications. The purpose of treatment is long-term re...Crohn's disease (CD) is a chronic relapsing and remitting autoinflammatory disorder of the gastrointestinal tract that has many intestinal and extraintestinal complications. The purpose of treatment is long-term remission, reduction of complications, and improvement of patients' quality of life. In many cases, this can be quite challenging and it is necessary to have a well thought out management strategy. We present the case of a 38-year-old woman with fistulizing CD that manifested as diffuse abdominal pain and bloody diarrhea accompanied by arthralgia. In addition, there were ulcerative lesions surrounded by cutaneous inflammation and erythema on her extremities, indicative of pyoderma gangrenosum. The patient was treated with high doses of parenteral methylprednisolone without any improvement and was started on adalimumab. A positive response to adalimumab therapy was observed: after 2 mo of therapy, the ulcerative skin lesion healed completely and the enterogastric fistula was closed affcer 5 mo adalimumab treatment. Adalimumab might be a suitable initial as well as maintenance therapy in patients with complicated CD.展开更多
The SOX2 protein is an important transcription factor functioning during the early development of animals. In this study, we isolated a full-length c DNA sequence of scallop Chlamys farreri sox2, Cf-sox2 which was 219...The SOX2 protein is an important transcription factor functioning during the early development of animals. In this study, we isolated a full-length c DNA sequence of scallop Chlamys farreri sox2, Cf-sox2 which was 2194 bp in length with a 981 bp open reading frame encoding 327 amino acids. With real-time PCR analysis, it was detected that Cf-sox2 was expressed in unfertilized oocytes, fertilized eggs and all the tested embryos and larvae. The expression level increased significantly(P < 0.01) in embryos from 2-cell to blastula, and then decreased significantly(P < 0.01) and reached the minimum in umbo larva. Moreover, location of the Cfsox2 expression was revealed using whole mount in situ hybridization technique. Positive hybridization signal could be detected in the central region of unfertilized oocytes and fertilized eggs, and then strong signals dispersed throughout the embryos from 2-cell to gastrula. During larval development, the signals were concentrated and strong signals were restricted to 4 regions of viscera mass in veliger larva. In umbo larva, weak signals could be detected in regions where presumptive visceral and pedal ganglia may be formed. The expression pattern of Cf-sox2 during embryogenesis was similar to that of mammal sox2, which implied that Cf-SOX2 may participate in the regulation of early development of C. farreri.展开更多
TOWARDS the end of last year, a Chinese magazine released a list of the country’s buzzwords of 2006. It was no surprise that "Innovation" ranked third. That year witnessed a nationwide campaign of sci-tech innova...TOWARDS the end of last year, a Chinese magazine released a list of the country’s buzzwords of 2006. It was no surprise that "Innovation" ranked third. That year witnessed a nationwide campaign of sci-tech innovation that reached unprecedented heat. And this time, the flames spread inland, to places like the frontier province of Yunnan.展开更多
Using a homogenized daily maximum temperature(T_(max))dataset across China,this study characterized the spatiotemporal variation of the onset date of extreme hot days in a year(i.e.,FirstEHD)during 1960-2018.Inhomogen...Using a homogenized daily maximum temperature(T_(max))dataset across China,this study characterized the spatiotemporal variation of the onset date of extreme hot days in a year(i.e.,FirstEHD)during 1960-2018.Inhomogeneous trends of FirstEHD over China during 1960-2018 can be found,with the advanced trend of FirstEHD over most parts in China,while a number of stations in North-Central China(NC)show the delayed trend of FirstEHD.Moreover,there exist interdecadal changes of FirstEHD trend,with a remarkable difference in the trend magnitude before and after the 1990s over South China(SC),and the sign of trend can even reverse from negative to positive after the 1990s in Xinjiang(XJ)and Yangtze River Basin(YR),and from positive to negative in NC.The overall trends of FirstEHD over NC,YR,and XJ during 1960-2018 are dominated by the trends before the 1990s,while they are dominated by the sharp advance after the 1990s over SC.It is further found that the trend of FirstEHD can generally be explained by the long-term trend in T_(max) over most parts of China,but the contribution from T_(max) variabilities is also non-negligible and can even account for more than 75% of the overall trend over NC.The possible factors responsible for the decadal changes in FirstEHD trends are also discussed.展开更多
Three pod lengths ( 10 cm, 10–20 cm and 20 cm) and 13 pre-sowing treatments were considered with four dates of collection (9 February, 19 February, 1 March and 11 March) to investigate their effect on germination...Three pod lengths ( 10 cm, 10–20 cm and 20 cm) and 13 pre-sowing treatments were considered with four dates of collection (9 February, 19 February, 1 March and 11 March) to investigate their effect on germination rate and growth of seedlings of Albizia lebbeck (L.) Benth. at Pundibari, West Bengal, India. The best time of pod collection was on 19 February as the germination rate of the seeds collected on this date was 92.5% without requiring any pre-sowing treatments. This clearly indicated that the seeds collected on 19 February were non-dormant, viable and physiologically mature. Significantly better seedling growth was also obtained when the seeds were sown on 19 February which was extracted from pods of length 10-20 cm. Application of thio-urea as a pre-treatment did not significantly enhanced seed germination rate, but its application in lower concentration (100 μL·L-1) resulted in better seedling growth and development.展开更多
MyoD, Myf5, and myogenin are myogenic regulatory factors that play important roles during myogenesis. It is thought that MyoD and Myf5 are required for myogenic determination, while myogenin is important for terminal ...MyoD, Myf5, and myogenin are myogenic regulatory factors that play important roles during myogenesis. It is thought that MyoD and Myf5 are required for myogenic determination, while myogenin is important for terminal differentiation and lineage maintenance. To better understand the function of myogenic regulatory factors in muscle development of flounder, an important economic fish in Asia, real-time quantitative RT-PCR was used to characterize the expression patterns of MyoD, Myf5, and myogenin at early stages of embryo development, and in different tissues of the adult flounder. The results show that, MyJ5 is the first gene to be expressed during the early stages of flounder development, followed by MyoD and myogenin. The expressions ofMyf5, MyoD, and myogenin at the early stages have a common characteristic: expression gradually increased to a peak level, and then gradually decreased to an extremely low level. In the adult flounder, the expression of the three genes in muscle is much higher than that in other tissues, indicating that they are important for muscle growth and maintenance of grown fish. During embryonic stages, the expression level of MyoD might serve an important role in the balance between muscle cell differentiation and proliferation. When the MyoD expression is over 30% of its highest level, the muscle cells enter the differentiation stage.展开更多
Many researchers have concluded that longer life expectancies prompt increased investment in education,as a prolonged labor supply raises the rate of return on education.Besides explaining the empirical evidence behin...Many researchers have concluded that longer life expectancies prompt increased investment in education,as a prolonged labor supply raises the rate of return on education.Besides explaining the empirical evidence behind this conclusion(at an absolute level),there is another issue to be discussed:does time spent studying and working increase proportionally with higher longevity? Building on an extended life-cycle model,this paper shows that prolonged life expectancy will cause individuals to increase their time in education but may not warrant rises in labor input.Later we show that higher improvement rate of longevity rather than initial life expectancy will promote economic growth,even we exclude the mechanism of human capital formation,and only consider growth effects of higher improvement rate of life expectancy from physical capital investment.展开更多
基金Supported by Youth Innovation Fund of Jiangxi Sciences of Agricultural Sciences(2013CQN010)Earmarked Fund for China Agriculture Research System(CARS-12-jxyzq)~~
文摘[Objective] This study was conducted to investigate effects of different intercropping modes on growth, yields and economic benefit of cassava and peanut in symbiotic period. [Method] With sole cropping of cassava (M1) and sole cropping of peanut (M2) as control groups, effects of intercropping of cassava with 1 row, 2 rows and 3 rows of peanut (M3, M4 and M5)on crop growth, yields and economic benefit were studied. [Result] Intercropping affected both growth and yields of cassava and peanut. Growth competition existed between cassava and peanut, and plant heights of cassava and peanut changed similarly. In late stages of intercropping, treatments M1, M2 and M5 showed higher plant heights under no nitrogen application, while treatment M3 and M4 exhibited higher plant heights under nitrogen application; intercropping improved leaf temperature, but no obvious law could be observed among different intercropping treatments; and intercropping improved total dry matter amount, which was the highest in M5 in root expanding stage and on the 30th day of the expanding stage, and the highest in M4 on the 60th day of the expanding stage. Intercropping reduced the yield of single plant, but improved the economic benefit of red upland soil; and under no nitrogen application and nitrogen application, cassava yields decreased by 25.35% and 14.55%, respectively, peanut yields decreased by 28.76% and 52.60%, respectively, while economic benefit increased by 72.90% and 56.82%, respectively. [Conclusion] Compared with sole cropping, interplanting cassava with 1 row, 2 rows or 3 rows of peanut could all improve economic benefit, and the economic benefit increased with number of rows of interplanted peanut increasing.
文摘Remarkable achievements have been made in China's agricultural development since the late 1970s. Nevertheless, deep-rooted problems are arising from inefficient farming practices. From mid- and long-term perspectives, migration of China's agricultural labor will slow and large-scale operation of farmland will accelerate. Although grain supply and demand have maintained a tight balance, new potentials still exist in improving grain production. Under the pressures of resource and environmental constraints, advancing the green and efficient transition of agriculture will become a new trend in China's agricultural development. In this context, the treatment of agricultural pollution, supply-side structural reform and innovation of agricultural subsidy policy are of strategic significance to the transition and upgrade of China's agriculture.
文摘This study was conducted to investigate the effects of different packaging methods on seed germination and vigor under a long-term bank storage condition, selecting suitable packaging materials and methods, and comprehensively estimate changes in seed vigor of seeds stored with different packaging materials. Hibiscus cannabinus L. seeds were stored in aluminium box, seed box, glass bottle, POlyethylene film bag, sack and kraft paper bag as packaging materials in a, long-term bank and tested for their seeds germinability, electrical conductivity and field seedling rate after 31 years. The results showed that the kenaf seeds with an initial germination rate of 88% exhibited the germination rates over 79.7% after being stored in the 6 packaging materials for 31 years, the germination rates of seeds packaged with paper bag and sack and of those sealed in film bag and aluminium box showed significantly decreased germination rates, while the seeds sealed in seed boxes and glass bottles exhibited non-significant decreases in seed germination rate, and their germination rates were still above 85%. Seed box and glass bottle were the packaging materials most suitable for long-term safe storage of kenaf seeds with a safe storage period long than 31 years.
基金Natural Science Foundation of Ningxia Hui Autonomous Region(B1007)~~
文摘The changes of physiological and biochemical indices in jujube fruits during the late development were investigated from 6-year-old jujube trees (Zizyphus jujuba Mill. cv. Lingwuchangzao). The results showed that the flesh firmness decreased slowly from white-green stage to full-red stage, being significantly related with the developmental maturity of jujube fruits negatively, the correlation coefficient reached -0.980 3^**. The contents of ascorbic acid and titratable acid in jujube fruits were significantly related with the developmental process of jujube fruits negatively or positively, the correlation coef- ficients were -0. 973 1^**and + 0. 974 6^ * * , respectively. The contents of soluble solids, total sugar, and sucrose increased with jujube ripening, while the relative sweetness of jujube fruits showed the same variation pattern, the correlation coefficients were 0. 996 6 ^* * , 0. 988 0^** , and 0. 982 8 ^* * , respectively. Before white-green stage during fruit development, the accumulation of monosaccharide was predominant in jujube fruits, following a fast accumulation of sucrose, indicating that the main component of sugars is sucrose at the crisp-ripe stage. Furthermore, the starch content of the flesh reached the peak at about thirty percentage of jujube maturity, being 51,54 mg/100 g.FW. The respiratory rates varied between 10 mg/( kg.h) and CO2 26 mg/( kg.h) after fruit turning red and before softening, indicating a non-climacteric respiratory type.
文摘The surge in China's local government debt has made various sectors of society pay closer attention to the situation. First of all, four types of debt relations must be clarified: the relationship between asset and non-asset debt, the difference between long- term and short-term debt, the difference between debt in the form of bonds and debt in the form of bank loans, and the difference between debt listed in government budgets and other government debt. The development of long-term bonds is a fairly good choice for China to upgrade its consumption structure, accelerate urbanization, transform its economic development patterns, and meanwhile, to alleviate the mismatch between the financial powers of local governments and their administrative responsibilities.
基金Professor Development Fund of Fujian Medical University
文摘AIM: To evaluate hepatic recurrence and prognostic factors for survival in patients with surgically resected hilar cholangiocarcinoma in a single institution over the last 13 years. METHODS: From 1994 to 2007, all patients with hilar cholangiocarcinoma referred to a surgical clinic were evaluated. Demographic data, tumor characteristics, and outcome were analyzed retrospectively. Outcome was compared in patients who underwent additional liver resection with resection of the tumor. RESULTS: Of the 69 patients submitted to laparotomy for tumor resection, curative resection (Ro resection) was performed in 40 patients, and palliative resection in 29. Thirty-one patients had only duct resection, and 38 patients had combined duct resection with liver resection including 34 total or part caudate lobes. Curative rates with the combined hepatectomy were significantly improved compared with those without additional hepatectomy (27/38 vs 13/31; X^2 = 5.94, P 〈 0.05). Concomitant liver resection was associated with a decreased incidence of initial recurrence in liver one year after surgery (11/38 vs 23/31; X^2 = 13.98, P 〈 0.01). The 3-year survival rate after Ro resection was 30.7% and was 10.5% for palliative resection. R0 resection improved the 3-year survival rate (30.7% vs 10.5%; X^2 = 12.47, P 〈 0.01).CONCLUSION: Hepatectomy, especially including the caudate lobe combined with bile duct resection should be considered standard treatment to cure hilar cholangiocarcinoma.
基金Supported by the Science Fund of Jiangsu Province(No.BY2015039-10)the Fund of Jiangsu Province Collaborative Center of Regional Modern Agriculture&Environmental Protection(No.HSXT219)the Science Fund of Changshu Science and Technology Bureau,China(No.CN201408)
文摘The objectives of the present study were to evaluate the yolk-sac and oil globule absorption and point of no return (PNR) ofpikeperch (Sander lucioperca L.) larvae. Artificial propagation ofpikeperch was performed at (15±2)℃. Yolk-sac absorption, oil globule absorption, larval growth and the first initial feeding rate were observed to analyze the early growth and to determine the PNR of pikeperch larvae. The total length of newly hatched (0 day after hatching, DAH) pikeperch larvae was (4.25±0.22) mm and the volume of the yolk-sac and the oil globule was (0.30±0.12)mm^3 and (5.14±2.28) 10-2 mm^3 respectively. The yolk-sac and the oil globule were exhausted at 11 DAH and 14 DAH, respectively. Pikeperch larvae began feeding at 8 DAH with an initial feeding rate about 10.0%. From 9 to 14 DAH, the initial feeding rate increased rapidly, and reached its highest (about 82.7%) at 14 DAH. It declined thereafter, 48.9% at 15 DAH and 35.6% at 16 DAH, thus the pikeperch larvae reached PNR by 15-16 DAH. The appropriate first feeding time for the pikeperch larvae is 11-12 DAH, when the initial feeding rate is higher than half of the maximum initial feeding rate.
基金Supported by 2015 Yeungnam University Research Grant,No.215A380205
文摘AIMTo evaluate complications and management outcomes of retained long-term plastic biliary stents.METHODSEndoscopic plastic biliary stent placement was performed in 802 patients at Yeungnam University Hospital between January 2000 and December 2014. Follow-up loss with a subsequently forgotten stent for more than 12 mo occurred in 38 patients. We retrospectively examined the cause of biliary stent insertion, status of stents, complications associated with biliary stents and management outcomes of long-term plastic biliary stents. Continuous variables were analyzed using the t test. Observed frequencies in subsets of the study population were compared using Fisher’s exact test and χ<sup>2</sup> tests. Statistical significance was defined as P < 0.05 (two-tailed).RESULTSMean age of patients was 73.7 ± 12 years and male-to-female ratio was 2.2:1. Indications of plastic biliary stent insertion were bile duct stones (63.2%, 24/38) and benign bile duct stricture (52.6%, 20/38). Mean duration of retained plastic stent was 22.6 ± 12.2 mo, and in 10 cases (26.3%), stents were retained for more than 24 mo. Common bile duct (CBD) stones or sludge were found in most cases (92.1%, 35/38). The most common complication was acute cholangitis (94.7%, 36/38). Stent removal by endoscopic approach was successfully performed in 92.1% (35/38) of the cases. In 3 cases, an additional plastic stent was inserted alongside the previous stent due to failure of the stent removal. Endoscopic removal of bile duct stones was successful in 73.7% (28/38) of the cases. When patients were divided into two groups by duration of stent placement (12 to 24 mo vs over 24 mo), there were no differences in the development of cholangitis, presence of biliary stones, and success rate of endoscopic removal of stones and biliary stents.CONCLUSIONThe most common complication of retained long-term plastic biliary stents was acute cholangitis associated with CBD stones. Endoscopic management was successfully performed in most cases.
基金supported by the National Key Technologies R & D Program of China (Grant No. 2011BAD13B03)
文摘The insulin-like growth factors Ⅰ and Ⅱ (IGF-Ⅰ and IGF-Ⅱ) are important proteins involved in fish growth and develop- ment. Here, we report the isolation of IGF-Ⅱ and expression analysis of IGFs in turbot Scophthalmus maximus, aiming to clarify their function in embryonic and larval development of fish. The deduced IGF-Ⅱ gene is 808 bp in full length, which encodes a protein of 219 amino acids and is 93% similar with that ofParalichthys olicaceus in amino acid sequence. The tissue abundance and the ex- pression pattern of IGFs in a turbot at early development stages were investigated via reverse transcription-polymer chain reaction. Result showed that the IGF-Ⅰ and IGF-Ⅱ genes were widely expressed in tissues of S. maximus. IGF-Ⅰ was detected in all tissues ex- cept intestines with the highest level in liver, while IGF-Ⅱ transcript presented in all tissues except muscle. At the stages of embry- onic and larval development, the mRNA levels of IGFs sharply increased from the stage of unfertilized egg to post larva, followed by a decrease with larval development. However, there was an increase in IGF-Ⅰ at the embryonic stage and IGF-Ⅱ at the gastrula stage, respectively. These results suggested that IGFs play important roles in cell growth and division of the turbot. Our study provides reference data for further investigation of growth regulation in turbot, which can guarantee better understanding of the physiological role that IGFs play in fish.
基金Supported by the National Key Technology Research and Development Program of China(Nos.2012BAD25B08,2012BAD25B00)
文摘The length-weight relationship and allometric growth patterns of hatchery-reared Chinese loach, Paramisgurnus dabryanus(Dabry de Thiersant, 1872), were determined from hatching to 60 days after hatching. A best power model was estimated for the length-weight relationship during the early life stages. Positive allometric growth for the head segment, trunk length, tail length and eye diameter was also found in the early life stages, while body depth, tail depth, tail fi n length, pectoral fi n length and barbel length displayed a negative coeffi cient. During the subsequent early developmental stage, the growth coeffi cients showed a clear and common tendency towards isometry for all measured body ratios. The allometric growth changes in Chinese loach during the early stage are possibly the result of selective organogenesis directed towards survival priorities.
文摘Crohn's disease (CD) is a chronic relapsing and remitting autoinflammatory disorder of the gastrointestinal tract that has many intestinal and extraintestinal complications. The purpose of treatment is long-term remission, reduction of complications, and improvement of patients' quality of life. In many cases, this can be quite challenging and it is necessary to have a well thought out management strategy. We present the case of a 38-year-old woman with fistulizing CD that manifested as diffuse abdominal pain and bloody diarrhea accompanied by arthralgia. In addition, there were ulcerative lesions surrounded by cutaneous inflammation and erythema on her extremities, indicative of pyoderma gangrenosum. The patient was treated with high doses of parenteral methylprednisolone without any improvement and was started on adalimumab. A positive response to adalimumab therapy was observed: after 2 mo of therapy, the ulcerative skin lesion healed completely and the enterogastric fistula was closed affcer 5 mo adalimumab treatment. Adalimumab might be a suitable initial as well as maintenance therapy in patients with complicated CD.
基金supported by the National High Technology Research and Development Program of China(863 Program)(2012AA10A402)
文摘The SOX2 protein is an important transcription factor functioning during the early development of animals. In this study, we isolated a full-length c DNA sequence of scallop Chlamys farreri sox2, Cf-sox2 which was 2194 bp in length with a 981 bp open reading frame encoding 327 amino acids. With real-time PCR analysis, it was detected that Cf-sox2 was expressed in unfertilized oocytes, fertilized eggs and all the tested embryos and larvae. The expression level increased significantly(P < 0.01) in embryos from 2-cell to blastula, and then decreased significantly(P < 0.01) and reached the minimum in umbo larva. Moreover, location of the Cfsox2 expression was revealed using whole mount in situ hybridization technique. Positive hybridization signal could be detected in the central region of unfertilized oocytes and fertilized eggs, and then strong signals dispersed throughout the embryos from 2-cell to gastrula. During larval development, the signals were concentrated and strong signals were restricted to 4 regions of viscera mass in veliger larva. In umbo larva, weak signals could be detected in regions where presumptive visceral and pedal ganglia may be formed. The expression pattern of Cf-sox2 during embryogenesis was similar to that of mammal sox2, which implied that Cf-SOX2 may participate in the regulation of early development of C. farreri.
文摘TOWARDS the end of last year, a Chinese magazine released a list of the country’s buzzwords of 2006. It was no surprise that "Innovation" ranked third. That year witnessed a nationwide campaign of sci-tech innovation that reached unprecedented heat. And this time, the flames spread inland, to places like the frontier province of Yunnan.
基金funded by the National Key Research and De-velopment Program of China[Grant number 2017YFA0604304]the National Natural Science Foundation of China[Grant number 41661144032].
文摘Using a homogenized daily maximum temperature(T_(max))dataset across China,this study characterized the spatiotemporal variation of the onset date of extreme hot days in a year(i.e.,FirstEHD)during 1960-2018.Inhomogeneous trends of FirstEHD over China during 1960-2018 can be found,with the advanced trend of FirstEHD over most parts in China,while a number of stations in North-Central China(NC)show the delayed trend of FirstEHD.Moreover,there exist interdecadal changes of FirstEHD trend,with a remarkable difference in the trend magnitude before and after the 1990s over South China(SC),and the sign of trend can even reverse from negative to positive after the 1990s in Xinjiang(XJ)and Yangtze River Basin(YR),and from positive to negative in NC.The overall trends of FirstEHD over NC,YR,and XJ during 1960-2018 are dominated by the trends before the 1990s,while they are dominated by the sharp advance after the 1990s over SC.It is further found that the trend of FirstEHD can generally be explained by the long-term trend in T_(max) over most parts of China,but the contribution from T_(max) variabilities is also non-negligible and can even account for more than 75% of the overall trend over NC.The possible factors responsible for the decadal changes in FirstEHD trends are also discussed.
文摘Three pod lengths ( 10 cm, 10–20 cm and 20 cm) and 13 pre-sowing treatments were considered with four dates of collection (9 February, 19 February, 1 March and 11 March) to investigate their effect on germination rate and growth of seedlings of Albizia lebbeck (L.) Benth. at Pundibari, West Bengal, India. The best time of pod collection was on 19 February as the germination rate of the seeds collected on this date was 92.5% without requiring any pre-sowing treatments. This clearly indicated that the seeds collected on 19 February were non-dormant, viable and physiologically mature. Significantly better seedling growth was also obtained when the seeds were sown on 19 February which was extracted from pods of length 10-20 cm. Application of thio-urea as a pre-treatment did not significantly enhanced seed germination rate, but its application in lower concentration (100 μL·L-1) resulted in better seedling growth and development.
基金Supported by the Key Laboratory of Experimental Marine Biology,Academia Sinica,Qingdao,Chinathe National High Technology Research and Development Program of China(863 Program)(No.2006AA10AA402)+1 种基金the National Basic Research Program of China(973Program)(Nos.2004CB117402,2010CB126304)the National Natural Science Foundation of China(No.30871929)
文摘MyoD, Myf5, and myogenin are myogenic regulatory factors that play important roles during myogenesis. It is thought that MyoD and Myf5 are required for myogenic determination, while myogenin is important for terminal differentiation and lineage maintenance. To better understand the function of myogenic regulatory factors in muscle development of flounder, an important economic fish in Asia, real-time quantitative RT-PCR was used to characterize the expression patterns of MyoD, Myf5, and myogenin at early stages of embryo development, and in different tissues of the adult flounder. The results show that, MyJ5 is the first gene to be expressed during the early stages of flounder development, followed by MyoD and myogenin. The expressions ofMyf5, MyoD, and myogenin at the early stages have a common characteristic: expression gradually increased to a peak level, and then gradually decreased to an extremely low level. In the adult flounder, the expression of the three genes in muscle is much higher than that in other tissues, indicating that they are important for muscle growth and maintenance of grown fish. During embryonic stages, the expression level of MyoD might serve an important role in the balance between muscle cell differentiation and proliferation. When the MyoD expression is over 30% of its highest level, the muscle cells enter the differentiation stage.
基金the POS DOC Research Fund(Grant No. 05646997) which is sponsored by the Shorenstein AsiaPacific Research Center at Stanford University
文摘Many researchers have concluded that longer life expectancies prompt increased investment in education,as a prolonged labor supply raises the rate of return on education.Besides explaining the empirical evidence behind this conclusion(at an absolute level),there is another issue to be discussed:does time spent studying and working increase proportionally with higher longevity? Building on an extended life-cycle model,this paper shows that prolonged life expectancy will cause individuals to increase their time in education but may not warrant rises in labor input.Later we show that higher improvement rate of longevity rather than initial life expectancy will promote economic growth,even we exclude the mechanism of human capital formation,and only consider growth effects of higher improvement rate of life expectancy from physical capital investment.