In order to understand the effect of geometric parameters and axial magnetic field on buoyant-thermocapillary convection during detached solidification, a series of threedimensional numerical simulations were conducte...In order to understand the effect of geometric parameters and axial magnetic field on buoyant-thermocapillary convection during detached solidification, a series of threedimensional numerical simulations were conducted by the finite-difference method. The results indicate that the stable flow is observed when the Marangoni number (Ma) is small; however, when the value of Ma increases and exceeds a threshold value, the stable steady flow transits to be unstable flow. As the height of the melt increases, the flow is enhanced at first and then gets weakened. As the width of gap decreases gradually, the strength of flow is enhanced. The approach of using axial magnetic field is an effective way to suppress the buoyant-thermocapillary convection. As the magnetic field strength increases, the inhibition is enhanced. The critical Marangoni number increases slightly with a greater melt height, a narrower width of gap, and a more strength of magnetic field.展开更多
Objective: To elongate human nerve axon in cultu re and search for suitable support matrices for peripheral nervous system trans plantation. Methods: Human embryo cortical neuronal cells,seeded on poly ( D,L-lactide-c...Objective: To elongate human nerve axon in cultu re and search for suitable support matrices for peripheral nervous system trans plantation. Methods: Human embryo cortical neuronal cells,seeded on poly ( D,L-lactide-co-glycolide) (PLGA) membrane scaffolds,were elongated with a se lf-made neuro-axon extending device. The growth and morphological changes of n euron axons were observed to measure axolemmal permeability after elongation. Ne urofilament protein was stained by immunohistochemical technique.Results: Human embryo neuron axon could be elongated and cultur ed on the PLGA membrane and retain their normal form and function. Conclusions: Three dimensional scaffolds with elongated neuron axon have the basic characteristics of artificial nerves,indicating a fundement al theory of nerve repair with elongated neuron axon.展开更多
基金Project(51076173)supported by the National Natural Science Foundation of China
文摘In order to understand the effect of geometric parameters and axial magnetic field on buoyant-thermocapillary convection during detached solidification, a series of threedimensional numerical simulations were conducted by the finite-difference method. The results indicate that the stable flow is observed when the Marangoni number (Ma) is small; however, when the value of Ma increases and exceeds a threshold value, the stable steady flow transits to be unstable flow. As the height of the melt increases, the flow is enhanced at first and then gets weakened. As the width of gap decreases gradually, the strength of flow is enhanced. The approach of using axial magnetic field is an effective way to suppress the buoyant-thermocapillary convection. As the magnetic field strength increases, the inhibition is enhanced. The critical Marangoni number increases slightly with a greater melt height, a narrower width of gap, and a more strength of magnetic field.
文摘Objective: To elongate human nerve axon in cultu re and search for suitable support matrices for peripheral nervous system trans plantation. Methods: Human embryo cortical neuronal cells,seeded on poly ( D,L-lactide-co-glycolide) (PLGA) membrane scaffolds,were elongated with a se lf-made neuro-axon extending device. The growth and morphological changes of n euron axons were observed to measure axolemmal permeability after elongation. Ne urofilament protein was stained by immunohistochemical technique.Results: Human embryo neuron axon could be elongated and cultur ed on the PLGA membrane and retain their normal form and function. Conclusions: Three dimensional scaffolds with elongated neuron axon have the basic characteristics of artificial nerves,indicating a fundement al theory of nerve repair with elongated neuron axon.