期刊文献+
共找到3篇文章
< 1 >
每页显示 20 50 100
密闭环境中二氯甲烷毒性的短期试验研究 被引量:3
1
作者 于庆祥 张恒太 +1 位作者 李秀英 魏永嘉 《航天医学与医学工程》 CAS CSCD 1995年第1期37-41,共5页
密闭环境下,小鼠吸入3500mg/m3、1750mg/m3、875mg/m3三种浓度的二氯甲烷气体,连续染毒8昼夜。结果表明:密闭环境本身对小鼠无影响。二氯甲烷毒性短期试验可使小鼠心、肝和肺脏体重量比升高,肾脏体重量... 密闭环境下,小鼠吸入3500mg/m3、1750mg/m3、875mg/m3三种浓度的二氯甲烷气体,连续染毒8昼夜。结果表明:密闭环境本身对小鼠无影响。二氯甲烷毒性短期试验可使小鼠心、肝和肺脏体重量比升高,肾脏体重量比降低,肝细胞出现水泡变性,心肌出现颗粒变性,并引起免疫器官萎缩,外周T淋巴细胞减少,抗体分泌细胞减少等变化。在这些变化中,有的达到统计学的显著水平,并出现明显的浓度-效应关系。 展开更多
关键词 二氯甲烷 闭密环境 免疫毒理 航空航天医学
下载PDF
Physiological responses of people in working faces of deep underground mines 被引量:5
2
作者 You Bo Wu Chao +1 位作者 Li Ji Liao Huimin 《International Journal of Mining Science and Technology》 SCIE EI 2014年第5期683-688,共6页
The research studied the influences of high temperature, high pressure, high humidity, noise and other harmful factors in mining conditions on the people health and safety, and investigated the impacts of confined env... The research studied the influences of high temperature, high pressure, high humidity, noise and other harmful factors in mining conditions on the people health and safety, and investigated the impacts of confined environmental on human physiology factors, including temperature, humidity, noise, pressure,toxic and harmful gases in terms of environmental characteristics in underground mines and an artificial intelligence system for simulation of the environment in a confined space of deep mines. Our results show that the systolic pressure, diastolic pressure, mean pressure, heart rate, respiratory rate, typing test speed and memory level percentage are negatively correlated with temperature value, and positively correlated with humidity value; the human temperature and weight are positively correlated with temperature value, and negatively correlated with humidity value. This research lays the foundation for the study of interaction between the deep confined space environment and safety behavior. 展开更多
关键词 Deep mine Confined space High temperature and high humidity Simulation experiment Human physiological index
下载PDF
Genotoxicity testing for radon exposure: Dolichopoda (Orthoptera, Rhaphidophoridae) as potential bio-indicator of confined environments
3
作者 Bianca GUSTAVINO Roberta MESCHINI +3 位作者 Giulia FRANZETTI Paolo GRATTON Giuliana ALLEGRUCCI Valerio SBORDONI 《Current Zoology》 SCIE CAS CSCD 2014年第2期299-307,共9页
Radon represents the major source of natural radioactivity in confined environments. Despite the clear evidence of a direct association between residential exposure and human lung cancer provided by case-control studi... Radon represents the major source of natural radioactivity in confined environments. Despite the clear evidence of a direct association between residential exposure and human lung cancer provided by case-control studies, results relating indoor exposure and genotoxic/mutagenic effect induction are still contradictory. The present study attempts to estimate the genotoxic effects induced by exposure to radioactive radon in wild cricket populations sampled from caves where varying concentrations of radon are present. Cave crickets are also tested as possible bio-indicator organisms of genotoxic potential of contaminated residential and confined environments. Six caves in Central Italy are considered covering a broad spectrum of radon radioactivity concentration (221-26,000 Bq/m3). Dolichopoda specimens were sampled from each cave; both haemocytes and brain cells taken from individuals were tested for responsiveness to DNA damage induced by radon through the Comet assay. Specimens from the least radioactive cave, housed in controlled conditions for 60 days before analysis, were used as control group. Statistically significant increase of DNA damage was found in all groups of individuals from each cave, for both cell types. Very low values of all Comet parameters were found in control group individuals, which gave indications of a good responsiveness of the organism to the variable environmental levels of radioactive contamination. Results indicate that cave crickets represent a reliable tool for the detection of genotoxic potential induced by radioactive contamination of confined environments and can be proposed as a possible bio-indicator system for air (-radioactive) pollution related to indoor exposure [Current Zoology 60 (2): 299-307, 2014]. 展开更多
关键词 High-LET natural-radioactivity Indoor exposure Cave crickets DNA primary damage Comet assay
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部