The artificial endocrine pancreas is a feedback control instrument that regulates insulin delivery on a minute-by-minute basis according to measured blood glucose levels. Only one type of bedsidetype artificial endocr...The artificial endocrine pancreas is a feedback control instrument that regulates insulin delivery on a minute-by-minute basis according to measured blood glucose levels. Only one type of bedsidetype artificial endocrine pancreas is now available in Japan: STG-22 (Nikkiso Co. Ltd., Japan). In the insulin infusion algorithm, insulin is infused on the basis ofits proportional and derivative actions, to blood glucose concentrations with a constant time delay. The bedside-type artificial endocrine pancreas has been proven to be useful not only as a therapeutic tool for diabetes mellitus, but also as an elegant research tool for investigating the pathophysiology of the disease, by using the euglycemic hyperinsulinemic glucose clamp technique. The wearable type of closed-loop system has been developed recently. The breakthrough is the establishment of a needle-type glucose sensor. The development of closed-loop glycemic control systems that enable long-term physiological regulation has focused on implantable devices. Much effort has been expended to realize these devices.展开更多
Aiming at closed-loop water system, by the method that shutting certain subcircuit, and solving the piping network, computing flow deviation of other subcircuits, then analyzing the rules of variation of stability wit...Aiming at closed-loop water system, by the method that shutting certain subcircuit, and solving the piping network, computing flow deviation of other subcircuits, then analyzing the rules of variation of stability with various factors, following conclusions are obtained： When reducing the resistance in main pipes, increasing resistance of subcircuits, system stability can be improved. Centralized regulation by changing power has no influence on system stability; centralized regulation by changing resistances will decrease system stability. Pump characteristics curve influences system stability, stability of the flat characteristic is superior to the steep one. For direct return system （DRS）, the stability of subcircuit which is farthest from the heat source is the worst. For reverse return system （RRS）, the stability of subcircuit in the middle of the pipe-network has the worst stability. Overall, stability of RRS is inferior to that of DRS.展开更多
A path following controller is proposed to force an underactuated surface ship which is suffering from disturbance to follow a predefined path.The controller is based on analytic model predictive control and unscented...A path following controller is proposed to force an underactuated surface ship which is suffering from disturbance to follow a predefined path.The controller is based on analytic model predictive control and unscented Kalman filter(UKF) techniques.The analytic model predictive control provides a systematic method to get appropriate controller parameters to guarantee the stability of the closed-loop system,and the well-defined relative degree is guaranteed by introducing output-redefinition.The UKF is used to estimate the states and uncertain parameters due to time-varying added mass matrices.With help of the proposed UKF-based controller,the underactuated ship with time-varying parameters can follow a desired straight path.Simulation results are presented to demonstrate the effectiveness of the proposed controller.展开更多
文摘The artificial endocrine pancreas is a feedback control instrument that regulates insulin delivery on a minute-by-minute basis according to measured blood glucose levels. Only one type of bedsidetype artificial endocrine pancreas is now available in Japan: STG-22 (Nikkiso Co. Ltd., Japan). In the insulin infusion algorithm, insulin is infused on the basis ofits proportional and derivative actions, to blood glucose concentrations with a constant time delay. The bedside-type artificial endocrine pancreas has been proven to be useful not only as a therapeutic tool for diabetes mellitus, but also as an elegant research tool for investigating the pathophysiology of the disease, by using the euglycemic hyperinsulinemic glucose clamp technique. The wearable type of closed-loop system has been developed recently. The breakthrough is the establishment of a needle-type glucose sensor. The development of closed-loop glycemic control systems that enable long-term physiological regulation has focused on implantable devices. Much effort has been expended to realize these devices.
文摘Aiming at closed-loop water system, by the method that shutting certain subcircuit, and solving the piping network, computing flow deviation of other subcircuits, then analyzing the rules of variation of stability with various factors, following conclusions are obtained： When reducing the resistance in main pipes, increasing resistance of subcircuits, system stability can be improved. Centralized regulation by changing power has no influence on system stability; centralized regulation by changing resistances will decrease system stability. Pump characteristics curve influences system stability, stability of the flat characteristic is superior to the steep one. For direct return system （DRS）, the stability of subcircuit which is farthest from the heat source is the worst. For reverse return system （RRS）, the stability of subcircuit in the middle of the pipe-network has the worst stability. Overall, stability of RRS is inferior to that of DRS.
基金the National Natural Science Foundation of China (No. 50779033)the National High Technology Research and Development Program (863) of China (No. 2007AA11Z250)
文摘A path following controller is proposed to force an underactuated surface ship which is suffering from disturbance to follow a predefined path.The controller is based on analytic model predictive control and unscented Kalman filter(UKF) techniques.The analytic model predictive control provides a systematic method to get appropriate controller parameters to guarantee the stability of the closed-loop system,and the well-defined relative degree is guaranteed by introducing output-redefinition.The UKF is used to estimate the states and uncertain parameters due to time-varying added mass matrices.With help of the proposed UKF-based controller,the underactuated ship with time-varying parameters can follow a desired straight path.Simulation results are presented to demonstrate the effectiveness of the proposed controller.
