肺表面活性蛋白C(surfactant protein C,SP-C)基因是目前被发现的唯一仅在肺泡Ⅱ型上皮细胞中表达的肺表面活性蛋白基因,其蛋白表达产物SP-C是构成肺表面活性物质的小分子疏水性蛋白之一,具有调节肺泡液-气界表面张力、维持肺表面活性...肺表面活性蛋白C(surfactant protein C,SP-C)基因是目前被发现的唯一仅在肺泡Ⅱ型上皮细胞中表达的肺表面活性蛋白基因,其蛋白表达产物SP-C是构成肺表面活性物质的小分子疏水性蛋白之一,具有调节肺泡液-气界表面张力、维持肺表面活性膜的稳定及参与肺器官局部防御体系等重要的生理功能。SP-C基因异常可造成SP-C结构变化和功能丧失,从而导致各种婴幼儿肺疾病,其中,肺间质性疾病(in- terstitial lung disease,ILD)的发病与SP-C基因突变的关系尤为密切。展开更多
The radial basis function （RBF） interpolation approach proposed by Freedman is used to solve inverse problems encountered in well-logging and other petrophysical issues. The approach is to predict petrophysical prop...The radial basis function （RBF） interpolation approach proposed by Freedman is used to solve inverse problems encountered in well-logging and other petrophysical issues. The approach is to predict petrophysical properties in the laboratory on the basis of physical rock datasets, which include the formation factor, viscosity, permeability, and molecular composition. However, this approach does not consider the effect of spatial distribution of the calibration data on the interpolation result. This study proposes a new RBF interpolation approach based on the Freedman＇s RBF interpolation approach, by which the unit basis functions are uniformly populated in the space domain. The inverse results of the two approaches are comparatively analyzed by using our datasets. We determine that although the interpolation effects of the two approaches are equivalent, the new approach is more flexible and beneficial for reducing the number of basis functions when the database is large, resulting in simplification of the interpolation function expression. However, the predicted results of the central data are not sufficiently satisfied when the data clusters are far apart.展开更多
In this paper, we study the asymptotic behavior of the solutions to the initial boundary value problem for unipolar drift diffusion equations for semiconductors. Under the proper assumptions on doping profile and init...In this paper, we study the asymptotic behavior of the solutions to the initial boundary value problem for unipolar drift diffusion equations for semiconductors. Under the proper assumptions on doping profile and initial value, we prove that the smooth solutions to these evolutionary problems tend to the unique stationary solution exponentially as time tends to infinity.展开更多
Based on the general solution of piezoelectric media and the extended Cerruti solution for tangential point forces acted on the surface of transversely isotropic piezoelectric half-space (Ding and Chen, 2001), the ele...Based on the general solution of piezoelectric media and the extended Cerruti solution for tangential point forces acted on the surface of transversely isotropic piezoelectric half-space (Ding and Chen, 2001), the electro-elastic fields in a transversely isotropic piezoelectric half-space caused by a circular flat bonded punch under torsion loading, which is called Reissner-Sagoci problem, are evaluated by first evaluating the displacement functions within the contact region and then differentiating them. All the coupling electro-elastic fields are expressed by elementary functions and are convenient to be used. Numerical results are finally presented.展开更多
The development of long linear structures such as roads, rail roads, tunnels, canals and pipelines often has unique engineering geology challenges. These include geological modeling, the identification of material str...The development of long linear structures such as roads, rail roads, tunnels, canals and pipelines often has unique engineering geology challenges. These include geological modeling, the identification of material strength and support factors, stability and risk issues, material excavation characteristics and the proposal of techniques for overcoming geotechnical problems, which are normally assessed as part of the conventional engineering geological investigation. An additional factor that is becoming increasingly important but is seldom included in investigations is the sustainability of the geotechnical inputs, in contrast to the sustainability of the project which is generally included. Sustainability issues revolve around the non-renewable nature of most construction resources and there is no doubt that the injudicious use of these construction materials and construction water is not sustainable in the long term: it is thus essential that the engineering geo-logical investigation should take cognizance of such issues and be adapted to provide the design engineer with the information that will maximize the sustainability options. This will also require a closer on-going relation-ship between the engineering geologist and the design engineer. This paper highlights significant sustainability issues (note that these differ from conventional environmental issues) and suggests some mitigating solutions. The sustainability issues discussed include primarily material and water usage, with some reference to energy conservation (mostly through alternative material usage and processing techniques and transportation).展开更多
Sufferers of breast cancer are often plagued by various psychological problems. Mastectomy, which has a serious influence on the female sex characteristics, can bring about especially serious psychological problems. T...Sufferers of breast cancer are often plagued by various psychological problems. Mastectomy, which has a serious influence on the female sex characteristics, can bring about especially serious psychological problems. These problems affect not only the patients’ quality of life but also the beginning, development, and end of the disease. This paper reviewed the relationships between the patients’ personal factors, the disease itself, treatment factors, and other socio-psychological factors and psychological conditions so as to provide new ideas for the psychological intervention on breast cancer patients, comprehensive clinical diagnosis and treatment, and prevention and cure.展开更多
This paper deals with two parabolic initial-boundary value problems in multidimensional domain. The first problem describes the situation where the spherical medium is static and the nonlinear reaction takes place onl...This paper deals with two parabolic initial-boundary value problems in multidimensional domain. The first problem describes the situation where the spherical medium is static and the nonlinear reaction takes place only at a single point. We show that under some conditions, the solution blows up in finite time and the blow-up set is the whole spherical medium. When the spherical medium is allowed to move in a special space, we investigate another parabolic initial-boundary value problem. It is proved that the blow-up can be avoided if the acceleration of the motion satisfies certain conditions.展开更多
The quality problem of the concrete body and backwall grouting of shaft lining must be taken into consideration during the engineering construction of the shaft. Detection and evaluation are needed to determine the pa...The quality problem of the concrete body and backwall grouting of shaft lining must be taken into consideration during the engineering construction of the shaft. Detection and evaluation are needed to determine the parameters such as the location and depth of drilling. The record of elastic wave can be gained through laying the surveying lines of the ring and ver- tical direction in the shaft lining by the elastic wave method. And specifically, through analyzing the different parameters of seismic attribute such as the velocity of high frequency reflection wave, amplitude and frequency, the abnormal range on the wall or under the wall can be forecasted. The concrete quality of shallow layer in the shaft lining can be evaluated through the velocity of surfer wave. Using the evaluating technique of comprehensive frequency and the phase feature of waveform, the basic features such as inner construction, wall back filling and failure depth of shaft lining can be interpreted from qualitatively to half quantitatively, and the interpreting section can be drawn. The results show that the detection effect for the shaft quality is significant by elastic wave technique, and the delineation of abnormal areas is accurate. Its guidance function is better for pro- duction.展开更多
基金supported by the National Science and Technology Major Projects(No.2011ZX05020-008)Well Logging Advanced Technique and Application Basis Research Project of Petrochina Company(No.2011A-3901)
文摘The radial basis function （RBF） interpolation approach proposed by Freedman is used to solve inverse problems encountered in well-logging and other petrophysical issues. The approach is to predict petrophysical properties in the laboratory on the basis of physical rock datasets, which include the formation factor, viscosity, permeability, and molecular composition. However, this approach does not consider the effect of spatial distribution of the calibration data on the interpolation result. This study proposes a new RBF interpolation approach based on the Freedman＇s RBF interpolation approach, by which the unit basis functions are uniformly populated in the space domain. The inverse results of the two approaches are comparatively analyzed by using our datasets. We determine that although the interpolation effects of the two approaches are equivalent, the new approach is more flexible and beneficial for reducing the number of basis functions when the database is large, resulting in simplification of the interpolation function expression. However, the predicted results of the central data are not sufficiently satisfied when the data clusters are far apart.
文摘In this paper, we study the asymptotic behavior of the solutions to the initial boundary value problem for unipolar drift diffusion equations for semiconductors. Under the proper assumptions on doping profile and initial value, we prove that the smooth solutions to these evolutionary problems tend to the unique stationary solution exponentially as time tends to infinity.
文摘Based on the general solution of piezoelectric media and the extended Cerruti solution for tangential point forces acted on the surface of transversely isotropic piezoelectric half-space (Ding and Chen, 2001), the electro-elastic fields in a transversely isotropic piezoelectric half-space caused by a circular flat bonded punch under torsion loading, which is called Reissner-Sagoci problem, are evaluated by first evaluating the displacement functions within the contact region and then differentiating them. All the coupling electro-elastic fields are expressed by elementary functions and are convenient to be used. Numerical results are finally presented.
文摘The development of long linear structures such as roads, rail roads, tunnels, canals and pipelines often has unique engineering geology challenges. These include geological modeling, the identification of material strength and support factors, stability and risk issues, material excavation characteristics and the proposal of techniques for overcoming geotechnical problems, which are normally assessed as part of the conventional engineering geological investigation. An additional factor that is becoming increasingly important but is seldom included in investigations is the sustainability of the geotechnical inputs, in contrast to the sustainability of the project which is generally included. Sustainability issues revolve around the non-renewable nature of most construction resources and there is no doubt that the injudicious use of these construction materials and construction water is not sustainable in the long term: it is thus essential that the engineering geo-logical investigation should take cognizance of such issues and be adapted to provide the design engineer with the information that will maximize the sustainability options. This will also require a closer on-going relation-ship between the engineering geologist and the design engineer. This paper highlights significant sustainability issues (note that these differ from conventional environmental issues) and suggests some mitigating solutions. The sustainability issues discussed include primarily material and water usage, with some reference to energy conservation (mostly through alternative material usage and processing techniques and transportation).
文摘Sufferers of breast cancer are often plagued by various psychological problems. Mastectomy, which has a serious influence on the female sex characteristics, can bring about especially serious psychological problems. These problems affect not only the patients’ quality of life but also the beginning, development, and end of the disease. This paper reviewed the relationships between the patients’ personal factors, the disease itself, treatment factors, and other socio-psychological factors and psychological conditions so as to provide new ideas for the psychological intervention on breast cancer patients, comprehensive clinical diagnosis and treatment, and prevention and cure.
基金Supported by the Innovation Project for University Prominent Research Talents of Henan (2003KJCX008)
文摘This paper deals with two parabolic initial-boundary value problems in multidimensional domain. The first problem describes the situation where the spherical medium is static and the nonlinear reaction takes place only at a single point. We show that under some conditions, the solution blows up in finite time and the blow-up set is the whole spherical medium. When the spherical medium is allowed to move in a special space, we investigate another parabolic initial-boundary value problem. It is proved that the blow-up can be avoided if the acceleration of the motion satisfies certain conditions.
文摘The quality problem of the concrete body and backwall grouting of shaft lining must be taken into consideration during the engineering construction of the shaft. Detection and evaluation are needed to determine the parameters such as the location and depth of drilling. The record of elastic wave can be gained through laying the surveying lines of the ring and ver- tical direction in the shaft lining by the elastic wave method. And specifically, through analyzing the different parameters of seismic attribute such as the velocity of high frequency reflection wave, amplitude and frequency, the abnormal range on the wall or under the wall can be forecasted. The concrete quality of shallow layer in the shaft lining can be evaluated through the velocity of surfer wave. Using the evaluating technique of comprehensive frequency and the phase feature of waveform, the basic features such as inner construction, wall back filling and failure depth of shaft lining can be interpreted from qualitatively to half quantitatively, and the interpreting section can be drawn. The results show that the detection effect for the shaft quality is significant by elastic wave technique, and the delineation of abnormal areas is accurate. Its guidance function is better for pro- duction.
