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基于案例引入的模拟间接Coombs实验在医学免疫学实验教学中的应用
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作者 贺亚玲 董冰心 +5 位作者 姜慧娇 刘欢 崔林 李玲 侯隽 陈雪玲 《现代医药卫生》 2024年第S01期137-138,共2页
目的完成Coombs实验需要自身免疫性疾病患者标本,但标本获取并不十分稳定,探索可以替代间接Coombs实验的临床标本和试剂,进行模拟间接Coombs实验,以期让学生掌握Coombs实验的原理和方法,明确临床意义。方法基于案例引入,用模拟临床标本... 目的完成Coombs实验需要自身免疫性疾病患者标本,但标本获取并不十分稳定,探索可以替代间接Coombs实验的临床标本和试剂,进行模拟间接Coombs实验,以期让学生掌握Coombs实验的原理和方法,明确临床意义。方法基于案例引入,用模拟临床标本和试剂,模拟间接Coombs实验方法,用已知抗原的红细胞测定受检血清中相应的不完全抗体。结果实验阳性结果红细胞出现凝集现象,阴性结果红细胞不凝集,这与临床上的Coombs实验结果一致。结论本研究能模拟Coombs实验,具有随时即时性且取材方便、成本低、无污染、实验方法简便,使用量开放,可满足学生反复实验的需要,适合于基层实验教学,并且实验阳性结果传递疾病的信息,便于学生认识临床上自身免疫性疾病。 展开更多
关键词 案例引入 模拟间接Coombs实验 医学免疫学 实验教学 教学应用
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基于WRF模式对华北一次飑线过程中雷电活动的间接和直接模拟研究 被引量:6
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作者 赵鹏国 银燕 +3 位作者 周筠珺 肖辉 康汉青 邓美玲 《气象科学》 北大核心 2017年第3期293-303,共11页
将非感应起电机制和放电参数化方案耦合到WRF模式的Morrison双参数微物理方案中,并在模式中引入了闪电潜势指数LPI,在此基础上模拟了2009年6月16日华北一次飑线过程,讨论模式对闪电活动再现能力。模拟结果显示,模式能够较好地再现雷达... 将非感应起电机制和放电参数化方案耦合到WRF模式的Morrison双参数微物理方案中,并在模式中引入了闪电潜势指数LPI,在此基础上模拟了2009年6月16日华北一次飑线过程,讨论模式对闪电活动再现能力。模拟结果显示,模式能够较好地再现雷达回波和降水分布特征,说明模式对此次飑线过程的宏观和微观特征具有一定的模拟能力。利用计算闪电潜势指数LPI的间接模拟,能够指示出大致的闪电分布特征,但闪电潜势指数LPI分布范围明显大于实际闪电落区;而通过耦合电过程的WRF模式直接输出闪电密度的直接模拟,模拟结果与实际闪电密度分布的对应关系较好,但由于模式中输出的闪电密度为总闪电密度,与观测地闪密度资料相比,模拟的闪电密度偏大。 展开更多
关键词 闪电活动 间接模拟 直接模拟 WRF模式
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混合教学模式在AR双目间接检眼镜模拟器教学中的应用 被引量:1
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作者 范媛媛 张赟 +1 位作者 李海东 郑斌 《中国继续医学教育》 2023年第20期112-117,共6页
目的评估混合教学模式在增强现实技术(augmented reality,AR)双目间接检眼镜模拟器课程中的效果。方法2021年12月—2022年3月,在温州医科大学附属眼视光医院杭州院区眼底病中心轮转的21名住培医生中开展《AR双目间接检眼镜模拟器课程》... 目的评估混合教学模式在增强现实技术(augmented reality,AR)双目间接检眼镜模拟器课程中的效果。方法2021年12月—2022年3月,在温州医科大学附属眼视光医院杭州院区眼底病中心轮转的21名住培医生中开展《AR双目间接检眼镜模拟器课程》,参与者被随机分为混合教学模式教学组(n=11)、对照组(n=10)。混合模式教学组接受线上理论线下操作的混合教学模式,对照组接受常规线下上机操作教学。最终以模拟器机载考核软件评估考试成绩量化教学效果,使用问卷评估对课程的满意度。结果混合模式教学组平均总分高于对照组,差异有统计学意义(P<0.05)。两组学生对课程总体满意度评分差异无统计学意义(P>0.05)。结论应用混合教学模式的试验组成绩优于对照组,考虑与混合教学模式增加学生学习目的性从而提升学习效果有关。在AR双目间接检眼镜模拟器课程的临床培训中混合教学模式是合理、有效的教学策略。 展开更多
关键词 增强现实技术 双目间接检眼镜模拟 线上线下混合模式 教学模式 教学策略 住院医师规范化培训 晕屏
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航空煤油冰点及黏温关系的分子动力学模拟 被引量:9
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作者 陈雪娇 侯磊 李师瑶 《石油科学通报》 2016年第3期493-502,共10页
航空煤油的冰点和黏温特性是衡量煤油低温流动性的重要质量指标。本文以某航空煤油的碳数分布、碳氢质量比、芳香烃饱和烃质量比等参数为依据,建立了5种烃混合的煤油体系模型,进行了分子动力学模拟。根据密度和扩散系数随温度的变化预... 航空煤油的冰点和黏温特性是衡量煤油低温流动性的重要质量指标。本文以某航空煤油的碳数分布、碳氢质量比、芳香烃饱和烃质量比等参数为依据,建立了5种烃混合的煤油体系模型,进行了分子动力学模拟。根据密度和扩散系数随温度的变化预测了煤油体系的冰点,模拟冰点值与实验结果一致;通过计算径向分布函数分析了冰点温度附近煤油体系内部的微观结构,发现同种分子间的聚集是影响煤油冰点温度的主要原因,芳香烃对煤油体系冰点的影响大于链状饱和烃的影响;采用Rouse Model模拟了煤油体系的黏温关系,模拟黏温指数与通过实验拟合的黏温指数相同,模拟黏度随温度的变化趋势与实验结果一致。 展开更多
关键词 航空煤油 分子动力学 冰点 间接模拟 黏温关系
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基于DDS驱动PLL结构的Ka波段频率合成器
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作者 张宾 邵宁修 《企业技术开发(中旬刊)》 2012年第8期137-139,共3页
随着通信技术与信息技术的不断发展,为了使频率资源能够得到充分的应用,现代通信、雷达以及导航系统等,其工作频率已逐渐由微波波段向毫米波波段发展,而毫米波频率合成器作为这些系统的主要部分,其性能好坏与系统的整体性能息息相关。另... 随着通信技术与信息技术的不断发展,为了使频率资源能够得到充分的应用,现代通信、雷达以及导航系统等,其工作频率已逐渐由微波波段向毫米波波段发展,而毫米波频率合成器作为这些系统的主要部分,其性能好坏与系统的整体性能息息相关。另外,随着上述各系统的工作频段逐渐向毫米波波段发展,毫米波频率合成器的需求也得到了急剧的增长。文章将介绍一种单片机控制的主要由直接数字频率合成器(DDS)、锁相环(PLL)以及倍频器等组成的频率合成技术来实现Ka波段频率合成器的方案,以及其电路仿真的设计。 展开更多
关键词 Ka波段频率合成器 DDS PLL 相位噪声 间接模拟式频率合成法
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The Role of the Aerosol Indirect Effect in the Northern Indian Ocean Warming Simulated by CMIP5 Models
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作者 HU Ning LI Li-Juan WANG Bin 《Atmospheric and Oceanic Science Letters》 CSCD 2014年第5期411-416,共6页
The northern Indian Ocean (NIO) experienced a decadal-scale persistent warming from 1950 to 2000, which has influenced both regional and global climate. Because the NIO is a region susceptible to aerosols emis- sion... The northern Indian Ocean (NIO) experienced a decadal-scale persistent warming from 1950 to 2000, which has influenced both regional and global climate. Because the NIO is a region susceptible to aerosols emis- sion changes, and there are still large uncertainties in the representation of the aerosol indirect effect (ALE) in CMIP5 (Coupled Model Intercomparison Project Phase 5) models, it is necessary to investigate the role of the AIE in the NIO warming simulated by these models. In this study, the authors select seven CMIP5 models with both the aerosol direct and indirect effects to investigate their performance in simulating the basin-wide decadal-scale NIO warming. The results show that the decreasing trend of the downwelling shortwave flux (FSDS) at the surface has the major damping effect on the SST increasing trend, which counteracts the warming effect of greenhouse gases (GHGs). The FSDS decreasing trend is mostly contrib- uted by the decreasing trend of cloudy-sky surface downwelling shortwave flux (FSDSCL), a metric used to measure the strength of the AIE, and partly by the clear-sky surface downwelling shortwave flux (FSDSC). Models with a relatively weaker AIE can simulate well the SST increasing trend, as compared to observation. In contrast, models with a relatively stronger AIE produce a much smaller magnitude of the increasing trend, indicat- ing that the strength of the AIE in these models may be overestimated in the NIO. 展开更多
关键词 Indian Ocean warming aerosol indirect ef-fect CMIP5
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Eulerian–Lagrangian simulation of bubble coalescence in bubbly flow using the spring-dashpot model 被引量:1
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作者 Jing Xue Feiguo Chen +1 位作者 Ning Yang Wei Ge 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2017年第3期249-256,共8页
The Eulerian–Lagrangian simulation of bubbly flow has the advantage of tracking the motion of bubbles in continuous fluid, and hence the position and velocity of each bubble could be accurately acquired. Previous sim... The Eulerian–Lagrangian simulation of bubbly flow has the advantage of tracking the motion of bubbles in continuous fluid, and hence the position and velocity of each bubble could be accurately acquired. Previous simulation usually used the hard-sphere model for bubble–bubble interactions, assuming that bubbles are rigid spheres and the collisions between bubbles are instantaneous. The bubble contact time during collision processes is not directly taken into account in the collision model. However, the contact time is physically a prerequisite for bubbles to coalesce, and should be long enough for liquid film drainage. In this work we applied the spring-dashpot model to model the bubble collisions and the bubble contact time, and then integrated the spring-dashpot model with the film drainage model for coalescence and a bubble breakage model. The bubble contact time is therefore accurately recorded during the collisions. We investigated the performance of the spring-dashpot model and the effect of the normal stiffness coefficient on bubble coalescence in the simulation.The results indicate that the spring-dashpot model together with the bubble coalescence and breakage model could reasonably reproduce the two-phase flow field, bubble coalescence and bubble size distribution. The influence of normal stiffness coefficient on simulation is also discussed. 展开更多
关键词 Bubble column Spring-dashpot model CoalescenceBreak-up Bubble size distribution
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Numerical and Experimental Study of Steel Space Truss with Stamped Connection
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作者 Cleirton Andre Silva de Freitas Luciano Mendes Bezerra Ramon Saleno Yure Costa Silva 《Journal of Civil Engineering and Architecture》 2011年第6期494-504,共11页
Tubular section members made of steel are common in space trusses. There are several types of connections to attach these members. The most popular is the staking end-flattened connection. The reduced cost and the fas... Tubular section members made of steel are common in space trusses. There are several types of connections to attach these members. The most popular is the staking end-flattened connection. The reduced cost and the fast assemblage of the truss are among the advantages of the staking end-flattened connection on 3D trusses. However, such connections present disadvantages like eccentricities and stiffness weakening of the tubular members. In this work, based on computer simulations and experimental lab tests on prototypes, small changes on the staking end-flattened connections such as reinforcement and eccentricity correction are evaluated. The results show an increase of 68% for local collapse and 17% for global collapse in the truss load carrying capacity when the suggested changes proposed in this article are used for the staking end-flattened connections. 展开更多
关键词 Truss load capacity space trusses end-flattened connections explosion.
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Clinical observation on tuina plus Baixiao moxibustion for temporomandibular joint dysfunction syndrome 被引量:2
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作者 Ding Chun-hua Zhang Qing Wei Hong-qin 《Journal of Acupuncture and Tuina Science》 CSCD 2019年第6期445-450,共6页
Objective:To observe the clinical effect of tuina plus Baixiao moxibustion in the treatment of temporomandibular joint dysfunction syndrome(TJDS).Methods:A total of 70 TJDS patients who met the inclusion criteria were... Objective:To observe the clinical effect of tuina plus Baixiao moxibustion in the treatment of temporomandibular joint dysfunction syndrome(TJDS).Methods:A total of 70 TJDS patients who met the inclusion criteria were randomized into an observation group and a control group by flipping a coin,with 35 cases in each group.Patients in the observation group were treated with tuina plus Baixiao moxibustion,while patients in the control group received oral intake of diclofenac potassium(75 mg/pill),1 pill after every dinner.Both tuina and Baixiao moxibustion were done once a day during treatment.The therapeutic evaluation was evaluated after 10 treatments in both groups.The maximum mouth opening distanee and visual analog scale(VAS)were observed before and after treatment,and the therapeutic efficacy was also compared.Results:After treatment,the maximum mouth opening distanee and VAS improved in both groups(all P<0.05);both items in the observation group were superior to those in the control group(both P<00.05).The total effective rate was 91.4%in the observation group,versus 74.3%in the control group,and the between-group comparison of the total effective rate showed statistical significanee(P<0.05).Conclusion:Tuina plus Baixiao moxibustion can effectively improve TJDS patient's temporomandibular joint function and alleviate pain,with better efficacy than oral intake of diclofenac potassium. 展开更多
关键词 TUINA MASSAGE Moxibustion Therapy Indirect Moxibustion Moxa Cone Moxibustion Baixiao Moxibustion Visual Analog Scale Temporomandibular Joint Dysfunotion Syndrome
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