The aim of our study was to explore the value of second-line treatment for advanced non-small cell lung cancer (NSCLC). One patient with metastatic adenocarcinoma of NSCLC was given second-line treatment of pemertrexe...The aim of our study was to explore the value of second-line treatment for advanced non-small cell lung cancer (NSCLC). One patient with metastatic adenocarcinoma of NSCLC was given second-line treatment of pemertrexed/cisplatin. Follow-up was made to observe progression free survival (PFS) and survival time. She was given 4 cycles first-line treatment of recombinant human endostatin plus gemcitabine/cisplatin previously; the efficacy was CR and PFS was 10.2 months. After the 5th cycle treatment of pemetrexed/cisplatin, the efficacy of the primary tumor was CR, and bone metastases was stable. PFS was 6.6 months, and the patient has been survival for 22 months. Quality of life (QOL) of the patient was improved. When advanced NSCLC is recurrence or metastasis, starting second-line treatment of pemetrexed/cisplatin timely can prolong survival time and improve QOL.展开更多
By studying the algorithms of single pattern matching, five factors that have effect on time complexity of the algorithm are analyzed. The five factors are： sorting the characters of pattern string in an increasing o...By studying the algorithms of single pattern matching, five factors that have effect on time complexity of the algorithm are analyzed. The five factors are： sorting the characters of pattern string in an increasing order of using frequency, utilizing already-matched pattern suffix information, utilizing already-matched pattern prefix information, utilizing the position factor which is absorbed from quick search algorithm, and utilizing the continue-skip idea which is originally proposed by this paper. Combining all the five factors, a new single pattern matching algorithm is implemented. It＇s proven by the experiment that the efficiency of new algorithm is the best of all algorithms.展开更多
文摘The aim of our study was to explore the value of second-line treatment for advanced non-small cell lung cancer (NSCLC). One patient with metastatic adenocarcinoma of NSCLC was given second-line treatment of pemertrexed/cisplatin. Follow-up was made to observe progression free survival (PFS) and survival time. She was given 4 cycles first-line treatment of recombinant human endostatin plus gemcitabine/cisplatin previously; the efficacy was CR and PFS was 10.2 months. After the 5th cycle treatment of pemetrexed/cisplatin, the efficacy of the primary tumor was CR, and bone metastases was stable. PFS was 6.6 months, and the patient has been survival for 22 months. Quality of life (QOL) of the patient was improved. When advanced NSCLC is recurrence or metastasis, starting second-line treatment of pemetrexed/cisplatin timely can prolong survival time and improve QOL.
基金the National Natural Science Foundation of China (Nos. 60502032 and 60672068)
文摘By studying the algorithms of single pattern matching, five factors that have effect on time complexity of the algorithm are analyzed. The five factors are： sorting the characters of pattern string in an increasing order of using frequency, utilizing already-matched pattern suffix information, utilizing already-matched pattern prefix information, utilizing the position factor which is absorbed from quick search algorithm, and utilizing the continue-skip idea which is originally proposed by this paper. Combining all the five factors, a new single pattern matching algorithm is implemented. It＇s proven by the experiment that the efficiency of new algorithm is the best of all algorithms.
