一站两场场间渡线道岔场联电路设计

对一站两场车站场间渡线道岔处的场联电路从故障导向安全的角度出发,在满足《集中联锁结合电路一般原则》(TB/T 2307-2017)对场联电路的技术要求的同时,将场间渡线道岔按照双动集中控制于一车场,将场间渡线道岔中间渡线绝缘作为两车场的运营界面划分,利用在渡线绝缘处设置虚拟信号机的方法,将跨线进路分为两段办理,在保证行车安全的前提下,简化场联电路设计,为同类型的工程设计起一定的参考作用。

简论格雷《墓园挽歌》的间渡性

通过引入间渡性这一概念,分析了英国诗人托马斯.格雷《墓园挽歌》中"新中有旧"即对古典主义的继承和"旧中有新"即对古典主义创作的革新和发展的特征,为解读这首诗歌开辟了新的途径。

乡间渡船

曾多次乘过渡船,在惊涛拍岸的长扛上,在烟波浩渺的太湖上,或在水光潋滟的西湖上,但总的感觉是既喧嚣又淡漠。而在扶贫点怀洪新河上乘渡船,田园诗般的人情味令人沉醉。 怀洪新河处泗洪境内,是淮河支流,也是自然乡界,乡民间交往颇为频繁。河上没有桥。

Effect of intermetallic compounds on heat resistance of hot roll bonded titanium alloy-stainless steel transition joint

The effect of intermetallic compounds on the heat resistance of transition joint was investigated. The experiment of post-weld heat treatment for the hot roll bonded titanium alloy-stainless steel joint using nickels interlayer was carried out, and the interface microstructure evolution due to heat treatment was presented. There was not found significant interdiffusion at stainless steel/nickel interface, when the specimens were heat treated in the temperature range of 600-800 °C for 10 and 30 min, while micro-cracks occurred at the stainless steel/nickel interface heat treated at 700 °C for 30 min. The thickness of intermetallic layers at nickel/titanium alloy interface increased at 600 °C, and micro-cracks occurred at 700 and 800 °C. The micro-cracks occurred between intermetallic layers or between intermetallic layer and nickel interlayer as well. The tensile strength of the transition joint decreased with the increase of heat treatment temperature or holding time.

Thiopurine use associated with reduced B and natural killer cells in inflammatory bowel disease

To identify which blood and mucosal lymphocyte populations are specifically depleted by thiopurine use in vivo.METHODSThe thiopurines azathioprine and 6-mercaptopurine have been a mainstay of inflammatory bowel disease (IBD) therapy for decades, but their mechanism of action in vivo remains obscure. Although thiopurines are lymphotoxic at high doses, and have been reported to cause T cell apoptosis in vitro, their ability to control IBD at lower doses suggests that they may selectively deplete particular lymphocyte populations. Blood cells from 19 IBD patients on a thiopurine, 19 IBD patients not on a thiopurine, and 38 matched healthy control subjects were analyzed by multiple multi-color flow cytometry panels to quantify the immune cell subsets contained therein, both as a percent of cells, and as an absolute cell count. Similar analyses were performed on colon biopsies from 17 IBD patients on a thiopurine, 17 IBD patients not on a thiopurine, and 49 healthy screening colonoscopy recipients.RESULTSComplete blood counts revealed lower lymphocyte, but not monocyte or granulocyte, counts in IBD patients who were taking thiopurines at the time of sampling. This reduction was restricted to CD3-negative lymphocytes, wherein both natural killer (NK) and B cells were significantly reduced among thiopurine recipients. Among CD19+ B cells, the transitional B cells were particularly depleted, being nearly absent in both blood and colon biopsies of thiopurine recipients. No differences were associated with thiopurine use in CD8+ T cells, mucosa-associated invariant T (MAIT) cells, invariant natural killer T (iNKT) cells, gamma/delta T cells, Th1, Th17, regulatory T cells (Tregs) or naïve CD4+ T cells. However, patients with IBD had significantly more circulating FOXP3+, Helios+ Tregs and fewer iNKT and MAIT cells than healthy controls.CONCLUSIONThiopurine use is associated with reduced B and NK cell, but not T cell, subpopulations in the blood of IBD patients.

USE OF PULSE TRANSIT TIME AS A MEASURE OF AUTONOMIC AROUSALS IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA

Objective To evaluate the feasibility of pulse transit time (PTT) arousals as an index of sleep fragmentation in patients with obstructive sleep apnea hypopnea syndrome (OSAHS). Methods Individuals referred for evaluation of possible OSAHS underwent overnight polysomnography (PSG). Three conventional indices of sleep fragmentation [electroencephalography (EEG) arousals, apnea/hypopnea index (AHI), oxygen desaturation index (ODI)], PTT arousals, and Epworth sleepiness scale (ESS) were compared. Results PTT arousals were positively correlated with EEG arousals (r= 0.746, P<0.001), AHI (r= 0.786, P<0.001), and ODI (r= 0.665, P<0.001), respectively. But, both PTT arousals and EEG arousals had no correlation with ESS (r= 0.432, P=0.201; r= 0.196, P=0.591, respectively). Conclusion PTT arousals are correlated well with other standard measures estimating severity of OSAHS and potentially a non-invasive marker with which to measure the sleep fragmentation in patients with OSAHS.

Diffusion bonding of Al 7075 and Mg AZ31 alloys:Process parameters, microstructural analysis and mechanical properties

Al 7075 and Mg AZ31 alloys were joined by diffusion bonding method. Joining process was performed in pressure range of 10-35 MPa at temperatures of 430-450 ℃ for 60 min under a vacuum of 13.3 MPa. The microstructure evaluation, phase analysis and distribution of elements at the interface were done using scanning electron microscopy （SEM）, energy-dispersive X-ray spectroscopy （EDS） and X-ray diffraction （XRD）. The pressure of 25 MPa was determined as the optimum pressure in which the minimum amount of plastic deformation takes place at the joint. Different reaction layers containing intermetallic compounds, such as Al12Mg17, Al3Mg2 andα（Al） solid solution, were observed, in interfacial transition zone （ITZ）. Thickness of layers was increased with increasing the operating temperature. According to the results, diffusion of aluminum atoms into magnesium alloy was more and the interface movement towards the Al alloy was observed. The maximum bond strength of 38 MPa was achieved at the temperature of 440 ℃ and pressure of 25 MPa. Fractography studies indicated that the brittle fracture originated from Al3Mg2 phase.

Next Generation Internet and IPv6 Transition

IPv4 address space has been exhausted since2011.The problem will be solved by moving forward to the next-generation Internet based on IPv6.Smooth transition from IPv4 to IPv6is the key to deciding whether the next-generation Internet is successful.IPv6-transition,hence,has been become the focus of both industry and academia.

Reflections on the management of agricultural economy in transition time of agricultural economy

In recent years, although farmers＇ income from agriculture is declining year by year, but the agricultural one is still the most important source of income. Factors determining the size of the total agricultural income are two sides： one is agricultural prices and the other is agricultural production. Obviously, because enhancements of China agricultural production capacity and several price increases of agricultural products, market saturation occurs in China＇ s major agricultural products and the price is close to or above the average level of international market. Simply relying on production increase and price hike has no longer satisfied growth needs of agricultural income.

Criteria for intermittent and continuous disturbance transition of ERA interaction with shaped charge jet

There are two interaction mechanisms between shaped charge jet and thin flying plate driven by explosion, that is, the intermittent and continuous disturbance. Determination of the transition criteria for the intermittent and continuous disturbance is of importance for the penetration calculation of the escaping jet and the design of ERA(explosive reactive armour). In this paper a new criteria was presented based on the analysis of interaction process, and the effects of NATO angle and thickness of flying plate on the disturbance frequency were discussed. It is shown that the critical shaped charge jet velocity increases with the plate thickness and NATO angle, especially increases drastically between 45° and 60°.

Integrated Statistical and Engineering Process Control Based on Smooth Transition Autoregressive Model

Traditional studies on integrated statistical process control and engineering process control (SPC-EPC) are based on linear autoregressive integrated moving average (ARIMA) time series models to describe the dynamic noise of the system.However,linear models sometimes are unable to model complex nonlinear autocorrelation.To solve this problem,this paper presents an integrated SPC-EPC method based on smooth transition autoregressive (STAR) time series model,and builds a minimum mean squared error (MMSE) controller as well as an integrated SPC-EPC control system.The performance of this method for checking the trend and sustained shift is analyzed.The simulation results indicate that this integrated SPC-EPC control method based on STAR model is effective in controlling complex nonlinear systems.

Advances and challenges in palladium-catalyzed intermolecular selective allylic C–H functionalization of alkenes

During the past decade, there was increased interest in the functionalization of the allylic C-H bond of alkenes. As opposed to traditional Trost-Tsuji reactions, this strategy avoids the prefunctionalization of the alkene. Many transi- tion metals have been used to promote such processes, and palladium has proved to be one of the best catalysts as it offers great advantages from the point of view of substrate scope and selectivity. Therefore, many groundbreaking re- suits obtained with Pd-catalyzed processes have been re- ported, including allylic C-H oxygenation, amination, al- kylation, and other transformations, which have been well documented in reviews [1].

The Ferry Cover Problem on Regular Graphs and Small-Degree Graphs

The ferry problem may be viewed as generalizations of the classical wolf-goatcabbage puzzle. The ferry cover problem is to determine the minimum required boat capacity to safely transport n items represented by a conflict graph. The Alcuin number of a conflict graph is the smallest capacity of a boat for which the graph possesses a feasible ferry schedule. In this paper the authors determine the Alcuin number of regular graphs and graphs with maximum degree at most five.

Fabrication of tunable hierarchical MXene@AuNPs nanocomposites constructed by self-reduction reactions with enhanced catalytic performances

MXene, a new type of two-dimensional layered transition metal carbide material differing from graphene, demonstrates intriguing chemical/physical properties and wide applications in recent years. Here, the preparation of the self-assembled MXene-gold nanoparticles （MXene@AuNPs） nanocomposites with tunable sizes is reported. The nano- composites are obtained via the self-reduction reactions of MXene material in a HAuCI4 solution at room temperature. The sizes of the Au particles can be well-controlled by reg- ulating the self-reduction reaction time. They can greatly in- fluence the catalytic behaviors of the MXene@AuNPs composites. MXene@AuNPs composites with optimized re- duction time show high catalytic performances and good cycle stability for model catalytic reactions of nRro-compounds, such as 2-nitrophenol and 4-nitrophenol. This work demon- strates a new approach for the preparation of tunable MXene- based self-assembled composites.

Large eddy simulation of unsteady transitional flow on the low-pressure turbine blade

The aim of this paper is to predict the phenomenon of laminar separation, transition and reattachment in a low-pressure turbine （LPT）. Self-developed large eddy simulation program of compressible N-S equations was used to describe the flow structures of T 106A LPT blade profile at Reynolds number of 1.1×10^5 based on the exit isentropic velocity and chord length. The com- putational results show the distributions of time-averaged wall-static pressure coefficient and mean skin-friction coefficient on the blade surface. The locations of laminar separation and reattachment points occur around 87% and 98% axial chord, which agree well with experiment data. The two-dimensional shear layer is gradually unstable along the downstream half of the suc- tion side as a result of the spanwise fluctuation and the roll up of shear layer via Kelvin-Helmholtz （KH） instability. Three-dimensional motions appear near 84% axial chord which later triggers spanwise vortexes and streamwise vortexes, leading to transition to turbulence in the separation bubble. Through introducing the concept of dissipation function, the high loss mainly comes from the places where strong shear layer and intense fluctuation exist. Furthermore, the separation region is only an accumulation center of the low-energy fluid rather than an area of loss source.