Icing on the surface of aircraft will not only aggravate its quality and affect flight control,but even cause safety accidents,which is one of the important factors restricting all-weather flight.Bio-inspired anti-ici...Icing on the surface of aircraft will not only aggravate its quality and affect flight control,but even cause safety accidents,which is one of the important factors restricting all-weather flight.Bio-inspired anti-icing surfaces have gained great attention recently due to their low-hysteresis,non-stick properties,slow nucleation rate and low ice adhesion strength.These bio-inspired anti-icing surfaces,such as superhydrophobic surfaces,slippery liquid-infused porous surfaces and quasi-liquid film surfaces,have realized excellent anti-icing performance at various stages of icing.However,for harsh environment,there are still many problems and challenges.From the perspective of bioinspiration,the mechanism of icing nucleation,liquid bounce and ice adhesion has been reviewed together with the application progress and bottleneck issues about anti-icing in view of the process of icing.Subsequently,the reliability and development prospect of active,passive and active-passive integrated anti-icing technology are discussed,respectively.展开更多
In this paper, on the basis of the analysis of the current situation of the mine floor flood and the consultation system study, the overall design and structure, specially, the mechanism of many kinds of method for ma...In this paper, on the basis of the analysis of the current situation of the mine floor flood and the consultation system study, the overall design and structure, specially, the mechanism of many kinds of method for making a strategic decision and reasoning of the system of prevention and control of mine floor flood are introduced. The applied examples are given at last.展开更多
To solve the greasiness and irritation risks brought about by organic sun-screening agents in sunscreen emulsions,in this work,a sunscreen O/W/Si multiple emulsion was prepared by two-step emulsification method,in whi...To solve the greasiness and irritation risks brought about by organic sun-screening agents in sunscreen emulsions,in this work,a sunscreen O/W/Si multiple emulsion was prepared by two-step emulsification method,in which the outer oil phase was silicone oil and the inner oil phase was solid lipid nanoparticles coated with organic sun-screening agent.Several influencing factors on the formation and stability of the emulsion were analyzed,including inorganic salts,the volume fraction of outer oil phase(silicone oil),and the dosage of W/O emulsifier.The in vitro sunscreen performance,water resistance and skin permeability of different types of sunscreen emulsions were further studied.The results showed that the sunscreen O/W/Si multiple emulsion containing 22.5%silicone oil,2.5%emulsifier and 0.2%NaCl had the best stability under the experimental conditions.The SPF value and water resistance of sunscreen O/W/Si multiple emulsion were slightly higher than those of sunscreen W/O emulsion,but significantly higher than those of sunscreen O/W emulsion.Compared with sunscreen W/O emulsion,the in vitro transdermal permeability of organic sun-screening agent in sunscreen O/W/Si multiple emulsion was reduced by approximately 60%,indicative of higher safety and good application prospect in sunscreen cosmetics.展开更多
OBJECTIVE: To explore the role and mechanism of a radiation protection cream(Rp) in the treatment of radiation dermatitis, and to accumulate necessary technical information for a new drug report on Rp.METHODS: High-pe...OBJECTIVE: To explore the role and mechanism of a radiation protection cream(Rp) in the treatment of radiation dermatitis, and to accumulate necessary technical information for a new drug report on Rp.METHODS: High-performance liquid chromatography was used to establish the method of measuring the main effective ingredients of sovereign and adjuvant herbs of Rp drugs, and to formulate the draft quality standards of Rp. A total of 48Sprague-Dawley male rats were randomly divided into the Model,Trolamine cream(Tc), Rp and Blank groups according to a random number table method.The skin of each rat's buttocks was irradiated using an electron linear accelerator to establish an acute radiation dermatitis model. The histological changes were observed under light microscopy and electron microscopy during wound healing and the effect of Rp on rat fibroblast Ku70/80 gene expression was detected at the transcriptional level.RESULTS: Pathological examination revealed that Rp protected the cellular and subcellular structures of skin after irradiation, promoting the proliferation and restoration of collagen fibers. Ku70/80 mRNA expression levels in the Rp and Tc groups were higher than that in the model group(P<0.05).Moreover,The majority of grade radiation dermatitis relative to the Model, Rp and Tc groups for reducing grade Ⅲ and Ⅳ dermatitis efficiency were 85.7%and 69.2%(P<0.05), respectively.The efficacy of Rp group in treating radiation dermatitis was better than the Trolamine cream group by16.5%(P<0.05).CONCLUSION: Compared with Tc, Rp had certain advantages in the efficacy and performance to price ratio.Thus, Rp is considered an effective alternative formulation for the prevention and treatment of radiation dermatitis.展开更多
基金financially supported by the National Natural Science Foundation of China(Nos.T2121003,51725501,51935001,52205297).
文摘Icing on the surface of aircraft will not only aggravate its quality and affect flight control,but even cause safety accidents,which is one of the important factors restricting all-weather flight.Bio-inspired anti-icing surfaces have gained great attention recently due to their low-hysteresis,non-stick properties,slow nucleation rate and low ice adhesion strength.These bio-inspired anti-icing surfaces,such as superhydrophobic surfaces,slippery liquid-infused porous surfaces and quasi-liquid film surfaces,have realized excellent anti-icing performance at various stages of icing.However,for harsh environment,there are still many problems and challenges.From the perspective of bioinspiration,the mechanism of icing nucleation,liquid bounce and ice adhesion has been reviewed together with the application progress and bottleneck issues about anti-icing in view of the process of icing.Subsequently,the reliability and development prospect of active,passive and active-passive integrated anti-icing technology are discussed,respectively.
文摘In this paper, on the basis of the analysis of the current situation of the mine floor flood and the consultation system study, the overall design and structure, specially, the mechanism of many kinds of method for making a strategic decision and reasoning of the system of prevention and control of mine floor flood are introduced. The applied examples are given at last.
文摘To solve the greasiness and irritation risks brought about by organic sun-screening agents in sunscreen emulsions,in this work,a sunscreen O/W/Si multiple emulsion was prepared by two-step emulsification method,in which the outer oil phase was silicone oil and the inner oil phase was solid lipid nanoparticles coated with organic sun-screening agent.Several influencing factors on the formation and stability of the emulsion were analyzed,including inorganic salts,the volume fraction of outer oil phase(silicone oil),and the dosage of W/O emulsifier.The in vitro sunscreen performance,water resistance and skin permeability of different types of sunscreen emulsions were further studied.The results showed that the sunscreen O/W/Si multiple emulsion containing 22.5%silicone oil,2.5%emulsifier and 0.2%NaCl had the best stability under the experimental conditions.The SPF value and water resistance of sunscreen O/W/Si multiple emulsion were slightly higher than those of sunscreen W/O emulsion,but significantly higher than those of sunscreen O/W emulsion.Compared with sunscreen W/O emulsion,the in vitro transdermal permeability of organic sun-screening agent in sunscreen O/W/Si multiple emulsion was reduced by approximately 60%,indicative of higher safety and good application prospect in sunscreen cosmetics.
基金Supported by the Science and Technology Development Project of Jinan(No.201121057)
文摘OBJECTIVE: To explore the role and mechanism of a radiation protection cream(Rp) in the treatment of radiation dermatitis, and to accumulate necessary technical information for a new drug report on Rp.METHODS: High-performance liquid chromatography was used to establish the method of measuring the main effective ingredients of sovereign and adjuvant herbs of Rp drugs, and to formulate the draft quality standards of Rp. A total of 48Sprague-Dawley male rats were randomly divided into the Model,Trolamine cream(Tc), Rp and Blank groups according to a random number table method.The skin of each rat's buttocks was irradiated using an electron linear accelerator to establish an acute radiation dermatitis model. The histological changes were observed under light microscopy and electron microscopy during wound healing and the effect of Rp on rat fibroblast Ku70/80 gene expression was detected at the transcriptional level.RESULTS: Pathological examination revealed that Rp protected the cellular and subcellular structures of skin after irradiation, promoting the proliferation and restoration of collagen fibers. Ku70/80 mRNA expression levels in the Rp and Tc groups were higher than that in the model group(P<0.05).Moreover,The majority of grade radiation dermatitis relative to the Model, Rp and Tc groups for reducing grade Ⅲ and Ⅳ dermatitis efficiency were 85.7%and 69.2%(P<0.05), respectively.The efficacy of Rp group in treating radiation dermatitis was better than the Trolamine cream group by16.5%(P<0.05).CONCLUSION: Compared with Tc, Rp had certain advantages in the efficacy and performance to price ratio.Thus, Rp is considered an effective alternative formulation for the prevention and treatment of radiation dermatitis.
