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蛋白质O-GlcNAc糖基化及其细胞生物学功能 被引量:6
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作者 杨新颖 李静 耿美玉 《细胞生物学杂志》 CSCD 2007年第5期682-686,共5页
糖基化是蛋白质翻译后修饰的一项重要内容,大多数蛋白质糖基化发生在细胞膜表面,且糖链结构复杂。而发生在细胞浆与细胞核内的、单个O-GlcNAc修饰的蛋白质糖基化现象,因其独特的细胞定位、糖链连接方式以及重要的生物学调控作用而日益... 糖基化是蛋白质翻译后修饰的一项重要内容,大多数蛋白质糖基化发生在细胞膜表面,且糖链结构复杂。而发生在细胞浆与细胞核内的、单个O-GlcNAc修饰的蛋白质糖基化现象,因其独特的细胞定位、糖链连接方式以及重要的生物学调控作用而日益成为糖生物学领域研究的热点。现对蛋白质O-GlcNAc修饰及其细胞生物学功能研究进展情况进行综述。 展开更多
关键词 O-GLCNAC O-磷酸化 OGT O-GLCNACASE 阴-阳学说
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A novel understanding about oxidization of glucose in term of Wuxing TCM theory 被引量:4
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作者 Fang Hui Li Shengjie +2 位作者 Zhu Qiuhong Pan Huiyun Xiao Dangsheng 《World Journal of Integrated Traditional and Western Medicine》 2016年第1期31-36,共6页
Yin-yang theory and Wuxing theory are the core parts of Traditional Chinese Medicine(TCM). Most of researches on Wuxing theory are based on the paradigm of TCM or Traditional Chinese Culture. It is an evitable chall... Yin-yang theory and Wuxing theory are the core parts of Traditional Chinese Medicine(TCM). Most of researches on Wuxing theory are based on the paradigm of TCM or Traditional Chinese Culture. It is an evitable challenge to interpret Wuxing theory in the term of biomolecular, biochemistry, stem cell and so on. The oxidation of glucose is the important pathway in cell and there are five basic factors which will be responsible for the undergoing of this reaction. The relationships among these factors are similar to Wuxing theory just like inter-promotion and inter-restraint. So, this understanding on Wuxing theory maybe take some advancement for the modernization of TCM. 展开更多
关键词 Wuxing theory Oxidation Metabolism Inter-promotion Inter-restraint System biology.
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